Walter Willett

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Long-term intake of vitamins and carotenoids and odds of early age-related cortical and posterior subcapsular lens opacities
    Allen Taylor
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 75:540-9. 2002
  2. doi request reprint Current evidence on healthy eating
    Walter C Willett
    Department of Nutrition, School of Public Health, Harvard University, Boston, Massachusetts 02115, USA
    Annu Rev Public Health 34:77-95. 2013
  3. doi request reprint Dietary fats and coronary heart disease
    W C Willett
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Intern Med 272:13-24. 2012
  4. pmc The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide
    Monica H Carlsen
    Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
    Nutr J 9:3. 2010
  5. ncbi request reprint Overview and perspective in human nutrition
    Walter C Willett
    Harvard School of Public Health, Department of Nutrition, 665 Huntington Avenue, Boston, MA 02115, USA
    Asia Pac J Clin Nutr 17:1-4. 2008
  6. ncbi request reprint The role of dietary n-6 fatty acids in the prevention of cardiovascular disease
    Walter C Willett
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Cardiovasc Med (Hagerstown) 8:S42-5. 2007
  7. ncbi request reprint Merging and emerging cohorts: not worth the wait
    Walter C Willett
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Nature 445:257-8. 2007
  8. ncbi request reprint Assessment of questionnaire validity for measuring total fat intake using plasma lipid levels as criteria
    W Willett
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 154:1107-12. 2001
  9. ncbi request reprint Not the time to abandon the food frequency questionnaire: point
    Walter C Willett
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 15:1757-8. 2006
  10. ncbi request reprint Cancer prevention and early detection
    Walter Willett
    Harvard School of Public Health Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 12:252s. 2003

Research Grants

  1. Risk Factors for Breast Cancer in Younger Nurses
    Walter Willett; Fiscal Year: 2007
  2. Risk Factors for Breast Cancer in Younger Nurses
    Walter Willett; Fiscal Year: 2007
  3. DIETARY ETILOGIES OF HEART DISEASE AND CANCER
    Walter Willett; Fiscal Year: 1999
  4. TRAINING GRANT IN ACADEMIC NUTRITION
    Walter Willett; Fiscal Year: 2007
  5. Cysteine, Related Gene Variants and Breast Cancer Risk
    Walter Willett; Fiscal Year: 2007
  6. Cysteine, Related Gene Variants and Breast Cancer Risk
    Walter Willett; Fiscal Year: 2009
  7. Risk Factors for Breast Cancer in Younger Nurses
    Walter Willett; Fiscal Year: 2009
  8. Cysteine, Related Gene Variants and Breast Cancer Risk
    Walter C Willett; Fiscal Year: 2010
  9. Prospective Studies of Diet and Cancer in Men and Wonen
    Walter Willett; Fiscal Year: 2006
  10. Risk Factors for Breast Cancer in Younger Nurses
    Walter Willett; Fiscal Year: 2006

Collaborators

Detail Information

Publications124 found, 100 shown here

  1. ncbi request reprint Long-term intake of vitamins and carotenoids and odds of early age-related cortical and posterior subcapsular lens opacities
    Allen Taylor
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 75:540-9. 2002
    ..Proper nutrition appears to protect against cataracts. Few studies have related nutrition to the odds of developing cortical or posterior subcapsular (PSC) cataracts...
  2. doi request reprint Current evidence on healthy eating
    Walter C Willett
    Department of Nutrition, School of Public Health, Harvard University, Boston, Massachusetts 02115, USA
    Annu Rev Public Health 34:77-95. 2013
    ..This article briefly summarizes major findings from recent years bearing on these issues...
  3. doi request reprint Dietary fats and coronary heart disease
    W C Willett
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    J Intern Med 272:13-24. 2012
    ....
  4. pmc The total antioxidant content of more than 3100 foods, beverages, spices, herbs and supplements used worldwide
    Monica H Carlsen
    Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Oslo, Norway
    Nutr J 9:3. 2010
    ..This database is intended for use in a wide range of nutritional research, from in vitro and cell and animal studies, to clinical trials and nutritional epidemiological studies...
  5. ncbi request reprint Overview and perspective in human nutrition
    Walter C Willett
    Harvard School of Public Health, Department of Nutrition, 665 Huntington Avenue, Boston, MA 02115, USA
    Asia Pac J Clin Nutr 17:1-4. 2008
    ..These findings have substantial relevance for many populations in Asia, where incidence of type 2 diabetes is rising rapidly...
  6. ncbi request reprint The role of dietary n-6 fatty acids in the prevention of cardiovascular disease
    Walter C Willett
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Cardiovasc Med (Hagerstown) 8:S42-5. 2007
    ..Reductions of linoleic acid to "improve" this ratio would likely increase rates of cardiovascular disease and diabetes...
  7. ncbi request reprint Merging and emerging cohorts: not worth the wait
    Walter C Willett
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Nature 445:257-8. 2007
  8. ncbi request reprint Assessment of questionnaire validity for measuring total fat intake using plasma lipid levels as criteria
    W Willett
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 154:1107-12. 2001
    ..These data provide additional evidence that informative measurements of dietary fat can be obtained by carefully constructed food frequency questionnaires...
  9. ncbi request reprint Not the time to abandon the food frequency questionnaire: point
    Walter C Willett
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 15:1757-8. 2006
  10. ncbi request reprint Cancer prevention and early detection
    Walter Willett
    Harvard School of Public Health Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 12:252s. 2003
  11. ncbi request reprint The Mediterranean diet: science and practice
    Walter C Willett
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Public Health Nutr 9:105-10. 2006
    ..To provide an overview of research relevant to the Mediterranean diet...
  12. ncbi request reprint Fish: balancing health risks and benefits
    Walter C Willett
    Harvard School of Public Health, Harvard University, Boston, Massachusetts 02115, USA
    Am J Prev Med 29:320-1. 2005
  13. ncbi request reprint Dietary pattern analysis for the evaluation of dietary guidelines
    Walter C Willett
    Harvard School of Public Health, Department of Nutrition, 665 Huntington Avenue, Boston, MA 02115, USA
    Asia Pac J Clin Nutr 17:75-8. 2008
    ..These analyses suggest that dietary guidelines should be evaluated for their ability to predict the occurrence of major illness, and that such analyses can help refine these guidelines...
  14. ncbi request reprint The search for truth must go beyond statistics
    Walter C Willett
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Epidemiology 19:655-6; discussion 657-8. 2008
    ..In other applications, epidemiology will be most successful when it is closely integrated with other areas of human biology...
  15. ncbi request reprint Balancing life-style and genomics research for disease prevention
    Walter C Willett
    Departments of Epidemiology and Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Science 296:695-8. 2002
    ..Thus, a balanced approach should provide the best data to make informed choices about the most effective means to prevent disease...
  16. ncbi request reprint Glycemic index, glycemic load, and risk of type 2 diabetes
    Walter Willett
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 76:274S-80S. 2002
    ....
  17. ncbi request reprint Fruit and vegetable intake and risk of major chronic disease
    Hsin Chia Hung
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Natl Cancer Inst 96:1577-84. 2004
    ..We evaluated the relationship between fruit and vegetable intake and the incidence of cardiovascular disease and cancer and of deaths from other causes in two prospective cohorts...
  18. ncbi request reprint Changes in caffeine intake and long-term weight change in men and women
    Esther Lopez-Garcia
    Department of Nutrition, Harvard School of Public Health, Cambridge, MA, USA
    Am J Clin Nutr 83:674-80. 2006
    ..The long-term effects of caffeine intake on weight have not been examined prospectively...
  19. ncbi request reprint Prospective study of major dietary patterns and stroke risk in women
    Teresa T Fung
    Department of Nutrition, Simmons College, 300 The Fenway, Boston, MA 02115, USA
    Stroke 35:2014-9. 2004
    ..Many foods have been suggested to influence the risk of stroke. However, no previous studies have examined the relationship between overall dietary patterns and risk of stroke...
  20. ncbi request reprint Vitamins and carotenoids intake and the risk of basal cell carcinoma of the skin in women (United States)
    Teresa T Fung
    Department of Nutrition, Simmons College, Boston, MA 02115, USA
    Cancer Causes Control 13:221-30. 2002
    ..We examined prospectively intakes of vitamins A. C, and E, folate, and specific carotenoids in relation to the risk of basal cell carcinoma of the skin (BCC) in women...
  21. ncbi request reprint Prospective study of dietary fat and risk of cataract extraction among US women
    Minyi Lu
    Nutritional Epidemiology Program, Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Epidemiol 161:948-59. 2005
    ..89, 95% CI: 0.81, 0.98; p(trend) = 0.01). The authors' findings suggest that higher intake of long-chain omega-3 fatty acid (eicosapentaenoic acid and docosahexaenoic acid) and consumption of fish may modestly reduce the risk of cataract...
  22. ncbi request reprint Purine-rich foods, dairy and protein intake, and the risk of gout in men
    Hyon K Choi
    Rheumatology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    N Engl J Med 350:1093-103. 2004
    ..Similarly, the possibility that the consumption of dairy products has a role in protecting against gout has been raised by metabolic studies. We prospectively investigated the association of these dietary factors with new cases of gout...
  23. ncbi request reprint Dietary fat and meat intake in relation to risk of type 2 diabetes in men
    Rob M van Dam
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Diabetes Care 25:417-24. 2002
    ..To examine dietary fat and meat intake in relation to risk of type 2 diabetes...
  24. ncbi request reprint Preconception homocysteine and B vitamin status and birth outcomes in Chinese women
    Alayne G Ronnenberg
    Departments of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 76:1385-91. 2002
    ..The associations between homocysteine, B vitamin status, and pregnancy outcomes have not been examined prospectively...
  25. pmc Sweetened beverage consumption and risk of coronary heart disease in women
    Teresa T Fung
    Department of Nutrition, Simmons College, Boston, MA 02115, USA
    Am J Clin Nutr 89:1037-42. 2009
    ..Previous studies have linked full-calorie sugar-sweetened beverages (SSBs) with greater weight gain and an increased risk of type 2 diabetes...
  26. pmc Prospective study of dietary patterns and chronic obstructive pulmonary disease among US women
    Raphaelle Varraso
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 86:488-95. 2007
    ..Although many foods and nutrients are associated with lung function or symptoms of chronic obstructive pulmonary disease (COPD), the relation between overall diet and newly diagnosed COPD is not known...
  27. pmc Lack of association between dietary protein intake and risk of stroke among middle-aged men
    Sarah Rosner Preis
    Departments of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 91:39-45. 2010
    ..Prospective cohort studies in Japanese populations have shown an inverse association between dietary protein and stroke risk. However, this association has not been examined among any study populations of US men...
  28. ncbi request reprint Carbohydrate intake and glycemic index in relation to the odds of early cortical and nuclear lens opacities
    Chung Jung Chiu
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 81:1411-6. 2005
    ..Animal studies suggest a role for dietary carbohydrate in cataractogenesis. However, few published human studies have evaluated associations between carbohydrate nutrition and lens opacification...
  29. pmc Physical activity in relation to long-term weight maintenance after intentional weight loss in premenopausal women
    Rania A Mekary
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Obesity (Silver Spring) 18:167-74. 2010
    ..Increased PA, particularly high intensity activities, is associated with better maintenance of weight loss. The benefits of activity were greater among overweight/obese than normal weight women...
  30. ncbi request reprint The association between magnesium intake and fasting insulin concentration in healthy middle-aged women
    Teresa T Fung
    Department of Nutrition, Simmons College, 300 The Fenway, Boston, MA 02215, USA
    J Am Coll Nutr 22:533-8. 2003
    ..We assessed the association between magnesium intake and fasting insulin levels in a large cohort of women...
  31. ncbi request reprint Folate, vitamin B6, and B12 intakes in relation to risk of stroke among men
    Ka He
    Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA
    Stroke 35:169-74. 2004
    ..However, the effects of intakes of these vitamins on risk of stroke are still uncertain. This study examines intakes of folate, vitamin B6, and B12 in relation to risk of ischemic and hemorrhagic stroke...
  32. ncbi request reprint Body iron stores and their determinants in healthy postmenopausal US women
    Jian meng Liu
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Am J Clin Nutr 78:1160-7. 2003
    ..Data on the determinants of body iron stores in middle-aged women are sparse...
  33. ncbi request reprint Dietary patterns, meat intake, and the risk of type 2 diabetes in women
    Teresa T Fung
    Department of Nutrition, Simmons College, Boston, Mass 02115, USA
    Arch Intern Med 164:2235-40. 2004
    ..To examine the association between major dietary patterns and risk of type 2 diabetes mellitus in a cohort of women...
  34. ncbi request reprint Dietary fat is not a major determinant of body fat
    Walter C Willett
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Am J Med 113:47S-59S. 2002
    ..Diets high in fat do not appear to be the primary cause of the high prevalence of excess body fat in our society, and reductions in fat will not be a solution...
  35. ncbi request reprint Dietary glycemic index and carbohydrate in relation to early age-related macular degeneration
    Chung Jung Chiu
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA
    Am J Clin Nutr 83:880-6. 2006
    ..Several dietary factors have been linked to age-related maculopathy (ARM), the early form of age-related macular degeneration, and there is reason to think that dietary carbohydrate may play a role in the development of ARM...
  36. ncbi request reprint Preconception folate and vitamin B(6) status and clinical spontaneous abortion in Chinese women
    Alayne G Ronnenberg
    Department of Environmental Health, Program for Population Genetics, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Obstet Gynecol 100:107-13. 2002
    ..To assess the association between preconception homocysteine and B vitamin status and risk of clinical spontaneous abortion in women from Anqing, China...
  37. ncbi request reprint Blood levels of long-chain polyunsaturated fatty acids, aspirin, and the risk of colorectal cancer
    Megan N Hall
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Cancer Epidemiol Biomarkers Prev 16:314-21. 2007
    ..Aspirin also inhibits the cyclooxygenase-2 enzyme and may share with n-3 fatty acids a potential mechanism to decrease the risk of colorectal cancer...
  38. pmc Point-of-purchase price and education intervention to reduce consumption of sugary soft drinks
    Jason P Block
    Department of Population Medicine, Harvard Medical School, Boston, MA 02215, USA
    Am J Public Health 100:1427-33. 2010
    ..We investigated whether a price increase on regular (sugary) soft drinks and an educational intervention would reduce their sales...
  39. ncbi request reprint Low-carbohydrate-diet score and the risk of coronary heart disease in women
    Thomas L Halton
    Departments of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 355:1991-2002. 2006
    ..Low-carbohydrate diets have been advocated for weight loss and to prevent obesity, but the long-term safety of these diets has not been determined...
  40. ncbi request reprint Alcohol intake and risk of incident gout in men: a prospective study
    Hyon K Choi
    Rheumatology Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Lancet 363:1277-81. 2004
    ..Additionally, potential differences in risk of gout posed by different alcoholic beverages have not been assessed...
  41. ncbi request reprint The association between fruit and vegetable consumption and peripheral arterial disease
    Hsin Chia Hung
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Epidemiology 14:659-65. 2003
    ..In this study, we evaluated the association of consumption of fruits and vegetables with peripheral arterial disease...
  42. pmc Bidirectional association between depression and type 2 diabetes mellitus in women
    An Pan
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Arch Intern Med 170:1884-91. 2010
    ..Although it has been hypothesized that the diabetes-depression relation is bidirectional, few studies have addressed this hypothesis in a prospective setting...
  43. ncbi request reprint Dietary patterns and the risk of postmenopausal breast cancer
    Teresa T Fung
    Department of Nutrition, Simmons College, Boston, MA 02115, USA
    Int J Cancer 116:116-21. 2005
    ..However, a Western-type diet may elevate risk of breast cancer among smokers, and a prudent diet may protect against estrogen receptive-negative tumors...
  44. ncbi request reprint Assessment of a dietary questionnaire in cancer patients receiving cytotoxic chemotherapy
    Jeffrey A Meyerhardt
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 23:8453-60. 2005
    ..Although several comprehensive dietary questionnaires have been validated and calibrated in healthy populations, similar studies have not been performed among cancer patients...
  45. ncbi request reprint Alcohol drinking patterns and risk of type 2 diabetes mellitus among younger women
    S Goya Wannamethee
    Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA
    Arch Intern Med 163:1329-36. 2003
    ..To examine the relationship between alcohol consumption and the incidence of type 2 diabetes mellitus among relatively young and middle-aged women...
  46. ncbi request reprint Prospective weight change and colon cancer risk in male US health professionals
    Lau Caspar Thygesen
    Department of Nutrition, Harvard School of Public Health, Boston, USA
    Int J Cancer 123:1160-5. 2008
    ..5. Our results add support that overweight and obesity are modifiable risk factors for colon cancer among men and suggest that weight has an important influence on colon cancer risk even in later life...
  47. pmc Pattern of dietary carbohydrate intake among urbanized adult Nigerians
    Sally N Akarolo-Anthony
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Int J Food Sci Nutr 64:292-9. 2013
    ..Our study showed that parboiled long grain white rice is now the most commonly consumed carbohydrate by urbanized Nigerians. Other traditional carbohydrate foods are still consumed frequently and remain quite popular...
  48. pmc Dietary flavonoid intakes and risk of type 2 diabetes in US men and women
    Nicole M Wedick
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 95:925-33. 2012
    ..Data from mechanistic studies support a beneficial effect of specific flavonoids on insulin sensitivity. However, few studies have evaluated the relation between intakes of different flavonoid subclasses and type 2 diabetes...
  49. ncbi request reprint Longitudinal study on the role of body size in premenopausal breast cancer
    Karin B Michels
    Department of Obstetrics and Gynecology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Arch Intern Med 166:2395-402. 2006
    ..A high body mass index (BMI) has been related to a reduced risk of breast cancer in premenopausal women. The mechanisms underlying this association have not been elucidated...
  50. pmc Body fatness at young ages and risk of breast cancer throughout life
    Heather J Baer
    Brigham and Women s Hospital, Boston, Massachusetts 02120, USA
    Am J Epidemiol 171:1183-94. 2010
    ..86 and RR = 0.92, respectively; P(heterogeneity) = 0.03). Body fatness at young ages has a strong and independent inverse relation to breast cancer risk throughout life...
  51. ncbi request reprint Dietary carotenoids and risk of lung cancer in a pooled analysis of seven cohort studies
    Satu Mannisto
    Harvard School of Public Health, Department of Nutrition, Boston, Massachusetts, USA
    Cancer Epidemiol Biomarkers Prev 13:40-8. 2004
    ..Although smoking is the strongest risk factor for lung cancer, greater intake of foods high in beta-cryptoxanthin, such as citrus fruit, may modestly lower the risk...
  52. ncbi request reprint Potato and french fry consumption and risk of type 2 diabetes in women
    Thomas L Halton
    Department of Nutrition and Epidemiology, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02215, USA
    Am J Clin Nutr 83:284-90. 2006
    ..Potatoes, a high glycemic form of carbohydrate, are hypothesized to increase insulin resistance and risk of type 2 diabetes...
  53. ncbi request reprint Glycemic index, glycemic load, and carbohydrate intake in relation to risk of distal colorectal adenoma in women
    Kyungwon Oh
    Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 13:1192-8. 2004
    ..Our findings do not support the hypothesis that a high glycemic index diet, a high glycemic load diet, or high carbohydrate intake overall are associated with risk of colorectal adenoma...
  54. pmc Population-level changes in folate intake by age, gender, and race/ethnicity after folic acid fortification
    Tanya G K Bentley
    Faculty of Arts and Sciences, Harvard University, Cambridge, Mass, USA
    Am J Public Health 96:2040-7. 2006
    ..We sought to quantify the impact of the 1998 US Food and Drug Administration (FDA) folic acid fortification policy by estimating folate intake at the population level...
  55. pmc Lactation and incidence of premenopausal breast cancer: a longitudinal study
    Alison M Stuebe
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, School of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Arch Intern Med 169:1364-71. 2009
    ..Findings from observational studies suggest an inverse association between lactation and premenopausal breast cancer risk, but results are inconsistent, and data from large prospective cohort studies are lacking...
  56. ncbi request reprint Early life risk factors in cancer: the relation of birth weight to adult obesity
    Nicole M Leong
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Int J Cancer 103:789-91. 2003
    ..76). These data suggest that both low and high birth weights are associated with higher adult BMI and support the hypothesis that fetal experience may influence adult obesity with potential consequences for risk of several major cancers...
  57. pmc Obesity as compared with physical activity in predicting risk of coronary heart disease in women
    Tricia Y Li
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 113:499-506. 2006
    ..The comparative importance of physical inactivity and obesity as predictors of coronary heart disease (CHD) risk remains unsettled...
  58. ncbi request reprint Whole-grain intake and the risk of type 2 diabetes: a prospective study in men
    Teresa T Fung
    Programs in Nutrition, Simmons College, Boston, MA 02115, USA
    Am J Clin Nutr 76:535-40. 2002
    ..Certain dietary components may play a role in the prevention of type 2 diabetes...
  59. pmc Intake of fiber and nuts during adolescence and incidence of proliferative benign breast disease
    Xuefen Su
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, 3rd Floor, Boston, MA 02115, USA
    Cancer Causes Control 21:1033-46. 2010
    ..We examined the association between adolescent fiber intake and proliferative BBD, a marker of increased breast cancer risk, in the Nurses' Health Study II...
  60. ncbi request reprint Tooth loss and dietary intake
    Hsin Chia Hung
    Department of Epidemiology, Harvard School of Public Health, Boston, USA
    J Am Dent Assoc 134:1185-92. 2003
    ..Several studies have reported that impaired dentition status is associated with poor nutritional intake. However, most of these studies are cross-sectional and thus are unable to clarify the temporal sequence...
  61. ncbi request reprint Antioxidant intake and primary open-angle glaucoma: a prospective study
    Jae H Kang
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, 181 Longwood Avenue, Boston, MA 02115, USA
    Am J Epidemiol 158:337-46. 2003
    ..97 (95% CI: 0.62, 1.52) for vitamin E, and 1.11 (95% CI: 0.82, 1.51) for vitamin A. In conclusion, the authors did not observe any strong associations between antioxidant consumption and the risk of primary open-angle glaucoma...
  62. ncbi request reprint Intake of zinc and antioxidant micronutrients and early age-related maculopathy lesions
    Martha Savaria Morris
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts 02111, USA
    Ophthalmic Epidemiol 14:288-98. 2007
    ..Results of observational and intervention studies have been inconsistent...
  63. ncbi request reprint A prospective study of trans fatty acids in erythrocytes and risk of coronary heart disease
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Circulation 115:1858-65. 2007
    ..We assessed the hypothesis that higher trans fatty acid contents in erythrocytes were associated with an elevated risk of CHD in a nested case-control study among US women...
  64. ncbi request reprint Weight status, abdominal adiposity, diabetes, and early age-related lens opacities
    Paul F Jacques
    Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging and Tufts University School of Nutrition Science and Policy, Tufts University, Boston, MA 02111, USA
    Am J Clin Nutr 78:400-5. 2003
    ..The association between weight status and the risk of lens opacities has received little attention...
  65. pmc Long-chain omega-3 fatty acids, fish intake, and the risk of type 2 diabetes mellitus
    Manas Kaushik
    Departments of Nutrition, Harvard Medical School and Brigham and Women s Hospital, Boston, MA, USA
    Am J Clin Nutr 90:613-20. 2009
    ..The role of long-chain omega-3 (n-3) fatty acids (LCFAs) in the development of T2DM remains unresolved. Objective: We examined the association between dietary LCFAs and incidence of T2DM in 3 prospective cohorts of women and men...
  66. ncbi request reprint Dietary linolenic acid intake is positively associated with five-year change in eye lens nuclear density
    Minyi Lu
    Nutritional Epidemiology Program, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Am Coll Nutr 26:133-40. 2007
    ..The present study was designed to examine the associations between dietary fat and the change in nuclear lens opacification over five years...
  67. ncbi request reprint Mercury and the risk of coronary heart disease in men
    Kazuko Yoshizawa
    Department of Nutrition, Harvard School of Public Health, Boston, USA
    N Engl J Med 347:1755-60. 2002
    ..A high dietary intake of mercury from consumption of fish has been hypothesized to increase the risk of coronary heart disease...
  68. ncbi request reprint Body mass index and mortality among US male physicians
    Umed A Ajani
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Ann Epidemiol 14:731-9. 2004
    ..To assess the relationship between body mass index and mortality in a population homogeneous in educational attainment and socioeconomic status...
  69. ncbi request reprint Breastfeeding during infancy and the risk of cardiovascular disease in adulthood
    Janet W Rich-Edwards
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts 02215, USA
    Epidemiology 15:550-6. 2004
    ..Only 2 studies have evaluated the relation between having been breastfed and the risk of adult cardiovascular events...
  70. ncbi request reprint The association between tooth loss and coronary heart disease in men and women
    Hsin Chia Hung
    Harvard School of Public Health, Boston, MA 02115, USA
    J Public Health Dent 64:209-15. 2004
    ..This paper evaluates the relation of tooth loss to incidence of coronary heart disease in two large cohort studies...
  71. ncbi request reprint Nut consumption and decreased risk of sudden cardiac death in the Physicians' Health Study
    Christine M Albert
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Ave E, Boston, MA 02215 1204, USA
    Arch Intern Med 162:1382-7. 2002
    ..Since components of nuts may have antiarrhythmic properties, part of the benefit may be due to a reduction in sudden cardiac death...
  72. ncbi request reprint Dietary fat intake and early age-related lens opacities
    Minyi Lu
    Nutritional Epidemiology Program and the Center for Ophthalmic Research, Department of Ophthalmology, Harvard Medical School and Brigham and Women s Hospital, Boston, MA, USA
    Am J Clin Nutr 81:773-9. 2005
    ..Dietary fat may affect lens cell membrane composition and function, which are related to age-related cataract...
  73. ncbi request reprint Dietary patterns and risk for type 2 diabetes mellitus in U.S. men
    Rob M van Dam
    Harvard School of Public Health, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts 02115, USA
    Ann Intern Med 136:201-9. 2002
    ..The role of diet in the development of type 2 diabetes mellitus remains unsettled...
  74. ncbi request reprint Coffee consumption and risk for type 2 diabetes mellitus
    Eduardo Salazar-Martinez
    Harvard School of Public Health, Channing Laboratory, Harvard Medical School, and Brigham and Women s Hospital, Boston, Massachusetts 02215, USA
    Ann Intern Med 140:1-8. 2004
    ..In small, short-term studies, acute administration of caffeine decreases insulin sensitivity and impairs glucose tolerance...
  75. ncbi request reprint Vitamin D intake and risk of incident hypertension: results from three large prospective cohort studies
    John P Forman
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Hypertension 46:676-82. 2005
    ..We conclude that higher intake of vitamin D is not associated with a lower risk of incident hypertension...
  76. ncbi request reprint Fruits and vegetables and ovarian cancer risk in a pooled analysis of 12 cohort studies
    Anita Koushik
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:2160-7. 2005
    ..Associations for total fruits and vegetables were similar for different histologic types. These results suggest that fruit and vegetable consumption in adulthood has no important association with the risk of ovarian cancer...
  77. ncbi request reprint Habitual caffeine intake and the risk of hypertension in women
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    JAMA 294:2330-5. 2005
    ..Caffeine acutely increases blood pressure, but the association between habitual consumption of caffeinated beverages and incident hypertension is uncertain...
  78. ncbi request reprint Fruits, vegetables and lung cancer: a pooled analysis of cohort studies
    Stephanie A Smith-Warner
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Int J Cancer 107:1001-11. 2003
    ..However, we cannot rule out the possibility that our results are due to residual confounding by smoking. The primary focus for reducing lung cancer incidence should continue to be smoking prevention and cessation...
  79. ncbi request reprint Calibration of a semi-quantitative food frequency questionnaire in early pregnancy
    Wafaie W Fawzi
    Department of Nutrition, Harvard School of Public Health and Harvard Pilgrim Health Care, Boston, MA
    Ann Epidemiol 14:754-62. 2004
    ..We assessed the validity of a semi-quantitative food frequency questionnaire (FFQ) among pregnant women...
  80. pmc Fructose-rich beverages and risk of gout in women
    Hyon K Choi
    Section of Rheumatology and Clinical Epidemiology Unit, Boston University School of Medicine, 650 Albany St, Ste 200, Boston, MA 02118, USA
    JAMA 304:2270-8. 2010
    ..Fructose-rich beverages such as sugar-sweetened soda and orange juice can increase serum uric acid levels and, thus, the risk of gout, but prospective data on the relationship are limited...
  81. ncbi request reprint Non-communicable diseases in sub-Saharan Africa: what we know now
    Shona Dalal
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Int J Epidemiol 40:885-901. 2011
    ....
  82. pmc Phobic anxiety is associated with higher serum concentrations of adipokines and cytokines in women with diabetes
    Aoife M Brennan
    Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes Care 32:926-31. 2009
    ..We aimed to determine whether associations of phobic anxiety with several known markers of CVD might be contributors...
  83. ncbi request reprint Prospective study of the association of changes in dietary intake, physical activity, alcohol consumption, and smoking with 9-y gain in waist circumference among 16 587 US men
    Pauline Koh-Banerjee
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 78:719-27. 2003
    ..Although it is known that abdominal obesity increases the risk of chronic diseases, prospective data examining the relation between lifestyle factors and the accumulation of abdominal adipose tissue are sparse...
  84. ncbi request reprint Changes in whole-grain, bran, and cereal fiber consumption in relation to 8-y weight gain among men
    Pauline Koh-Banerjee
    Department of Nutrition, Harvard School of Public Health, Boston, USA
    Am J Clin Nutr 80:1237-45. 2004
    ....
  85. ncbi request reprint High prevalence of hyperhomocysteinemia in Chinese adults is associated with low folate, vitamin B-12, and vitamin B-6 status
    Ling Hao
    Institute of Reproductive and Child Health, Peking University, Beijing 100083, China, and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Nutr 137:407-13. 2007
    ..Low plasma concentrations of folate, vitamins B-12 and B-6, older age, being male, and living in urban areas were all independently associated with elevated tHcy, with low folate as the strongest determinant...
  86. ncbi request reprint Dietary fat and risk of lung cancer in a pooled analysis of prospective studies
    Stephanie A Smith-Warner
    Harvard School of Public Health, Department of Nutrition, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 11:987-92. 2002
    ..These data do not support an important relation between fat or cholesterol intakes and lung cancer risk. The means to prevent this important disease remains avoidance of smoking...
  87. ncbi request reprint Changes in body weight and body fat distribution as risk factors for clinical diabetes in US men
    Pauline Koh-Banerjee
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Am J Epidemiol 159:1150-9. 2004
    ..5 cm. Our findings underscore the critical importance of maintaining weight and waist to reduce the risk of diabetes...
  88. ncbi request reprint Dairy consumption and risk of type 2 diabetes mellitus in men: a prospective study
    Hyon K Choi
    Department of Medicine, Massachusetts General Hospital, Boston, Mass 02114, USA
    Arch Intern Med 165:997-1003. 2005
    ..While a strong inverse association has been reported between dairy consumption and the insulin resistance syndrome among young obese adults, the relation between dairy intake and type 2 diabetes is unknown...
  89. ncbi request reprint A prospective study of breast size and premenopausal breast cancer incidence
    Aaron S Kusano
    Department of Epidemiology, Harvard School of Public Health, and Obstetrics and Gynecology Epidemiology Center, Brigham and Women s Hospital, Boston, MA 02115, USA
    Int J Cancer 118:2031-4. 2006
    ..Stratifying by BMI at age 18 at a cutoff point of 21 kg/m2 gave similar results. Larger bra cup size at a young age is associated with a higher incidence of premenopausal breast cancer, though this association is limited to leaner women...
  90. pmc Longitudinal study of birth weight and adult body mass index in predicting risk of coronary heart disease and stroke in women
    Janet W Rich-Edwards
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Avenue, Boston, MA 02215, USA
    BMJ 330:1115. 2005
    ..To determine whether birth weight and adult body size interact to predict coronary heart disease in women, as has been observed for men. To determine whether birth weight and adult body size interact to predict risk of stroke...
  91. ncbi request reprint A symposium and workshop report from the Global Nutrition and Epidemiologic Transition Initiative: nutrition transition and the global burden of type 2 diabetes
    Josiemer Mattei
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Br J Nutr 108:1325-35. 2012
    ....
  92. ncbi request reprint Lessons from dietary studies in Adventists and questions for the future
    Walter Willett
    Harvard School of Public Health and the Harvard Medical School, Boston, MA 02115, USA
    Am J Clin Nutr 78:539S-543S. 2003
    ..Resolution of these issues is needed to provide optimal guidance regarding healthy diets, and the newly funded Adventist Health Study will contribute importantly in this effort...
  93. pmc Meat mutagens and breast cancer in postmenopausal women--a cohort analysis
    Kana Wu
    Department of Nutrition, Harvard School of Public Health, and Department of Medicine, Brigham and Women s Hospital, 665 Huntington Avenue, Building 2, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 19:1301-10. 2010
    ..Mutagenic compounds produced when meats are cooked at high temperatures have been hypothesized to increase risk of breast cancer...
  94. pmc Fluorescent oxidation products and risk of coronary heart disease: a prospective study in women
    Majken K Jensen
    Department of Nutrition, Harvard School of Public Health, Boston, MA
    J Am Heart Assoc 2:e000195. 2013
    ..The objective of this study is to determine whether measures of FlOPs are associated with risk of CHD in women over an extended follow-up period...
  95. ncbi request reprint Plasma carotenoids and tocopherols and risk of myocardial infarction in a low-risk population of US male physicians
    A Elisabeth Hak
    Department of Epidemiology, Harvard School of Public Health, Channing Laboratory, 181 Longwood Ave, Boston, Mass 02115 5804, USA
    Circulation 108:802-7. 2003
    ..Increased intake of carotenoids and vitamin E may protect against myocardial infarction (MI). However, prospective data on blood levels of carotenoids other than beta-carotene and vitamin E (tocopherol) and risk of MI are sparse...
  96. ncbi request reprint Comparison of bioelectrical impedance and BMI in predicting obesity-related medical conditions
    Kamali Willett
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Obesity (Silver Spring) 14:480-90. 2006
    ..To determine the relative validity of specific bioelectrical impedance analysis (BIA) prediction equations and BMI as predictors of physiologically relevant general adiposity...
  97. ncbi request reprint Walking and leisure-time activity and risk of hip fracture in postmenopausal women
    Diane Feskanich
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    JAMA 288:2300-6. 2002
    ..Walking is the most common activity among older adults, and evidence suggests that it can increase femoral bone density and reduce fracture risk...
  98. pmc Prospective study of dietary patterns and chronic obstructive pulmonary disease among US men
    Raphaelle Varraso
    Department of Nutrition, Harvard School of Public Health, 655 Huntington Avenue, Boston, Massachusetts 02115, USA
    Thorax 62:786-91. 2007
    ..Because foods are consumed together and nutrients may interact, dietary patterns are an alternative way of characterising diet. A study was undertaken to assess the relation between dietary patterns and newly diagnosed COPD in men...
  99. pmc Prospective study of pre-gravid sugar-sweetened beverage consumption and the risk of gestational diabetes mellitus
    Liwei Chen
    Department of Epidemiology, School of Public Health, Louisiana State University Health Science Center, New Orleans, Louisiana, USA
    Diabetes Care 32:2236-41. 2009
    ..Studies on SSB consumption and glucose intolerance among pregnant women, however, are lacking. We therefore examined the association between regular SSB consumption before pregnancy and the risk of gestational diabetes mellitus (GDM)...
  100. ncbi request reprint Endogenous sex hormones, breast cancer risk, and tamoxifen response: an ancillary study in the NSABP Breast Cancer Prevention Trial (P-1)
    Mary S Beattie
    Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, CA, USA
    J Natl Cancer Inst 98:110-5. 2006
    ..The purpose of this study was to determine whether sex hormone levels were associated with breast cancer risk and with response to tamoxifen in a high-risk population...
  101. ncbi request reprint A new proposed guidance system for beverage consumption in the United States
    Barry M Popkin
    Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27516 3997, USA
    Am J Clin Nutr 83:529-42. 2006
    ..The Panel recommends that the consumption of beverages with no or few calories should take precedence over the consumption of beverages with more calories...

Research Grants26

  1. Risk Factors for Breast Cancer in Younger Nurses
    Walter Willett; Fiscal Year: 2007
    ..abstract_text> ..
  2. Risk Factors for Breast Cancer in Younger Nurses
    Walter Willett; Fiscal Year: 2007
    ..abstract_text> ..
  3. DIETARY ETILOGIES OF HEART DISEASE AND CANCER
    Walter Willett; Fiscal Year: 1999
    ....
  4. TRAINING GRANT IN ACADEMIC NUTRITION
    Walter Willett; Fiscal Year: 2007
    ..The Principal Investigator, Dr Walter Willett, and Co-Principal Investigator, Dr W Allan Walker, have established strong and vigorous pre- and postdoctoral ..
  5. Cysteine, Related Gene Variants and Breast Cancer Risk
    Walter Willett; Fiscal Year: 2007
    ....
  6. Cysteine, Related Gene Variants and Breast Cancer Risk
    Walter Willett; Fiscal Year: 2009
    ....
  7. Risk Factors for Breast Cancer in Younger Nurses
    Walter Willett; Fiscal Year: 2009
    ..Already, this study has identified multiple potentially modifiable risk factors for breast cancer in young women, and the extended follow-up should provide further information on the prevention of this and other important diseases. ..
  8. Cysteine, Related Gene Variants and Breast Cancer Risk
    Walter C Willett; Fiscal Year: 2010
    ....
  9. Prospective Studies of Diet and Cancer in Men and Wonen
    Walter Willett; Fiscal Year: 2006
    ..abstract_text> ..
  10. Risk Factors for Breast Cancer in Younger Nurses
    Walter Willett; Fiscal Year: 2006
    ..abstract_text> ..
  11. DIETARY ETILOGIES OF HEART DISEASE AND CANCER
    Walter Willett; Fiscal Year: 2000
    ....
  12. RISK FACTORS FOR BREAST CANCER AMONG YOUNGER NURSES
    Walter Willett; Fiscal Year: 2000
    ..In addition to the above aims, the NHS II provides the exposure data and initial case identification to examine many other important outcomes among young women. ..
  13. DIETARY ETILOGIES OF HEART DISEASE AND CANCER
    Walter Willett; Fiscal Year: 2001
    ....
  14. RISK FACTORS FOR BREAST CANCER AMONG YOUNGER NURSES
    Walter Willett; Fiscal Year: 2001
    ..In addition to the above aims, the NHS II provides the exposure data and initial case identification to examine many other important outcomes among young women. ..
  15. RISK FACTORS FOR BREAST CANCER AMONG YOUNGER NURSES
    Walter Willett; Fiscal Year: 2002
    ..In addition to the above aims, the NHS II provides the exposure data and initial case identification to examine many other important outcomes among young women. ..
  16. RISK FACTORS FOR BREAST CANCER AMONG YOUNGER NURSES
    Walter Willett; Fiscal Year: 2003
    ..In addition to the above aims, the NHS II provides the exposure data and initial case identification to examine many other important outcomes among young women. ..
  17. Risk Factors for Breast Cancer in Younger Nurses
    Walter Willett; Fiscal Year: 2004
    ..abstract_text> ..
  18. Risk Factors for Breast Cancer in Younger Nurses
    Walter Willett; Fiscal Year: 2005
    ..abstract_text> ..
  19. Risk Factors for Breast Cancer in Younger Nurses
    Walter Willett; Fiscal Year: 2006
    ..abstract_text> ..
  20. PROSPECTIVE STUDIES OF DIET AND CANCER IN MEN AND WOMEN
    Walter Willett; Fiscal Year: 2007
    ..The findings will contribute importantly to the prevention and prognosis of major cancers of men and women. ..
  21. Risk Factors for Breast Cancer in Younger Nurses
    Walter C Willett; Fiscal Year: 2010
    ..Already, this study has identified multiple potentially modifiable risk factors for breast cancer in young women, and the extended follow-up should provide further information on the prevention of this and other important diseases. ..