Sabine Wilhelm

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Motor inhibition in trichotillomania and obsessive-compulsive disorder
    Antje Bohne
    Massachusetts General Hospital Harvard Medical School, OCD Clinic, Simches Research Building, 2nd Floor, 185 Cambridge Street, Boston, MA 02114, USA
    J Psychiatr Res 42:141-50. 2008
  2. ncbi request reprint Modular cognitive-behavioral therapy for body dysmorphic disorder: a randomized controlled trial
    Sabine Wilhelm
    Massachusetts General Hospital and Harvard Medical School Electronic address
    Behav Ther 45:314-27. 2014
  3. pmc Randomized trial of behavior therapy for adults with Tourette syndrome
    Sabine Wilhelm
    Massachusetts General Hospital Harvard Medical School, Boston, 02114, USA
    Arch Gen Psychiatry 69:795-803. 2012
  4. ncbi request reprint Prevalence of body dysmorphic disorder in patients with anxiety disorders
    S Wilhelm
    OCD Clinic and Research Unit, Massachusetts General Hospital, Charlestown 02129, USA
    J Anxiety Disord 11:499-502. 1997
  5. ncbi request reprint Habit reversal versus supportive psychotherapy for Tourette's disorder: a randomized controlled trial
    Sabine Wilhelm
    Massachusett General Hospital, MA 02129, USA
    Am J Psychiatry 160:1175-7. 2003
  6. ncbi request reprint Challenges in treating obsessive-compulsive disorder: introduction
    Sabine Wilhelm
    Department of Psychiatry, Massachusetts General Hospital, Building 149, 13th Street, Charlestown, MA 02129, USA
    J Clin Psychol 60:1127-32. 2004
  7. ncbi request reprint Augmentation of behavior therapy with D-cycloserine for obsessive-compulsive disorder
    Sabine Wilhelm
    Obsessive Compulsive Disorder Clinic, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Psychiatry 165:335-41; quiz 409. 2008
  8. pmc Modular cognitive-behavioral therapy for body dysmorphic disorder
    Sabine Wilhelm
    Massachusetts General Hospital, Boston, MA 02114, USA
    Behav Ther 42:624-33. 2011
  9. ncbi request reprint Self-injurious skin picking: clinical characteristics and comorbidity
    S Wilhelm
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, USA
    J Clin Psychiatry 60:454-9. 1999
  10. ncbi request reprint Cognitive behavior group therapy for body dysmorphic disorder: a case series
    S Wilhelm
    Massachusetts General Hospital, Charlestown, USA
    Behav Res Ther 37:71-5. 1999

Detail Information

Publications64

  1. ncbi request reprint Motor inhibition in trichotillomania and obsessive-compulsive disorder
    Antje Bohne
    Massachusetts General Hospital Harvard Medical School, OCD Clinic, Simches Research Building, 2nd Floor, 185 Cambridge Street, Boston, MA 02114, USA
    J Psychiatr Res 42:141-50. 2008
    ..There was no evidence for motor inhibition deficits in OCD. Based on our data, a subgroup of TTM sufferers seems to be characterized by motor inhibition deficits...
  2. ncbi request reprint Modular cognitive-behavioral therapy for body dysmorphic disorder: a randomized controlled trial
    Sabine Wilhelm
    Massachusetts General Hospital and Harvard Medical School Electronic address
    Behav Ther 45:314-27. 2014
    ..Patient satisfaction was high, with a mean CSI score of 87.3% (SD=12.8%) at posttreatment. CBT-BDD appears to be a feasible, acceptable, and efficacious treatment that warrants more rigorous investigation. ..
  3. pmc Randomized trial of behavior therapy for adults with Tourette syndrome
    Sabine Wilhelm
    Massachusetts General Hospital Harvard Medical School, Boston, 02114, USA
    Arch Gen Psychiatry 69:795-803. 2012
    ..Medications for tics are often effective but can cause adverse effects. Behavior therapy may offer an alternative but has not been examined in a large-scale controlled trial in adults...
  4. ncbi request reprint Prevalence of body dysmorphic disorder in patients with anxiety disorders
    S Wilhelm
    OCD Clinic and Research Unit, Massachusetts General Hospital, Charlestown 02129, USA
    J Anxiety Disord 11:499-502. 1997
    ..In all cases, onset of social phobia preceded onset of BDD. Our findings draw attention to the prevalence of BDD in patients with social phobia. The potential etiologic significance of our findings is discussed...
  5. ncbi request reprint Habit reversal versus supportive psychotherapy for Tourette's disorder: a randomized controlled trial
    Sabine Wilhelm
    Massachusett General Hospital, MA 02129, USA
    Am J Psychiatry 160:1175-7. 2003
    ..The authors investigated the efficacy of habit reversal for Tourette's disorder, which is characterized by multiple motor and vocal tics...
  6. ncbi request reprint Challenges in treating obsessive-compulsive disorder: introduction
    Sabine Wilhelm
    Department of Psychiatry, Massachusetts General Hospital, Building 149, 13th Street, Charlestown, MA 02129, USA
    J Clin Psychol 60:1127-32. 2004
    ..The final article describes pharmacotherapy for OCD. All articles feature case vignettes and provide practitioners with clinical recommendations...
  7. ncbi request reprint Augmentation of behavior therapy with D-cycloserine for obsessive-compulsive disorder
    Sabine Wilhelm
    Obsessive Compulsive Disorder Clinic, Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Psychiatry 165:335-41; quiz 409. 2008
    ..This study examined whether d-cycloserine, a partial agonist at the N-methyl-D-aspartate (NMDA) glutamatergic receptor, enhances the efficacy of behavior therapy for obsessive-compulsive disorder (OCD)...
  8. pmc Modular cognitive-behavioral therapy for body dysmorphic disorder
    Sabine Wilhelm
    Massachusetts General Hospital, Boston, MA 02114, USA
    Behav Ther 42:624-33. 2011
    ..To our knowledge, this represents the first test of a broadly applicable, individual psychosocial treatment for BDD...
  9. ncbi request reprint Self-injurious skin picking: clinical characteristics and comorbidity
    S Wilhelm
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, USA
    J Clin Psychiatry 60:454-9. 1999
    ..The authors examined the demographics, phenomenology, and associated psychopathology in a series of 31 subjects with this problem...
  10. ncbi request reprint Cognitive behavior group therapy for body dysmorphic disorder: a case series
    S Wilhelm
    Massachusetts General Hospital, Charlestown, USA
    Behav Res Ther 37:71-5. 1999
    ..This finding adds to a nascent literature documenting the potential efficacy of short-term cognitive-behavior therapy for patients suffering from BDD...
  11. pmc Role of medial cortical networks for anticipatory processing in obsessive-compulsive disorder
    Kristina T Ciesielski
    Department of Radiology, MGH MIT HMS A A Martinos Center for Biomedical Imaging, Massachusetts General Hospital and McLean Hospital, Harvard Medical School, Charlestown, Massachusetts, USA
    Hum Brain Mapp 33:2125-34. 2012
    ....
  12. ncbi request reprint Visuospatial abilities, memory, and executive functioning in trichotillomania and obsessive-compulsive disorder
    Antje Bohne
    Massachusetts General Hospital Harvard Medical School, OCD Clinic, Charlestown, MA 02129, USA
    J Clin Exp Neuropsychol 27:385-99. 2005
    ..Other executive functions, as well as memory and visuospatial abilities were unimpaired in TTM and OCD. Our data suggest that TTM and OCD are characterized by different patterns of neuropsychological dysfunction...
  13. ncbi request reprint Prevalence of symptoms of body dysmorphic disorder and its correlates: a cross-cultural comparison
    Antje Bohne
    Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA
    Psychosomatics 43:486-90. 2002
    ..Body image concerns and preoccupation were significantly greater in American than in German students, although the prevalence of probable body dysmorphic disorder was not...
  14. ncbi request reprint Cognitive retraining for organizational impairment in obsessive-compulsive disorder
    Ulrike Buhlmann
    Department of Psychiatry OCD Clinic, Massachusetts General Hospital, Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA
    Psychiatry Res 144:109-16. 2006
    ..These findings support a distinction in OCD between failure to utilize a strategy and incapacity to implement a strategy...
  15. ncbi request reprint Skin picking in German students. Prevalence, phenomenology, and associated characteristics
    Antje Bohne
    Massachusetts General Hospital, Harvard Medical School, USA
    Behav Modif 26:320-39. 2002
    ..6%). About 20% (n = 26) ate the picked tissue afterward. Results suggest SP is an underrecognized problem that occurs on a continuum ranging from mild to severe with generally stable clinical characteristics across cultures...
  16. ncbi request reprint Functional magnetic resonance imaging study of regional brain activation during implicit sequence learning in obsessive-compulsive disorder
    Scott L Rauch
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129, USA
    Biol Psychiatry 61:330-6. 2007
    ..Here, we used the SRT and functional magnetic resonance imaging (fMRI) to replicate prior results in a larger sample and to test for relationships between regional activation and OCD symptom dimensions...
  17. ncbi request reprint Open-label escitalopram treatment for pathological skin picking
    Nancy J Keuthen
    Massachusetts General Hospital Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA
    Int Clin Psychopharmacol 22:268-74. 2007
    ..These results suggest that escitalopram can be an effective agent in reducing pathological skin picking. The lack of medication response in a subset of our sample suggests the possibility of pathological skin picking subtypes...
  18. ncbi request reprint Need for speed: evaluating slopes of OCD recovery in behavior therapy enhanced with d-cycloserine
    Gregory S Chasson
    Massachusetts General Hospital Harvard Medical School, Boston, MA 02114, USA
    Behav Res Ther 48:675-9. 2010
    ..Ultimately, DCS may provide a means for curtailing treatment costs, decreasing treatment dropout and refusal rates, and enhancing access to care...
  19. pmc Predictors of treatment outcome in modular cognitive therapy for obsessive-compulsive disorder
    Gail Steketee
    Boston University Schoolof Social Work, 264 Bay State Road, Boston, MA 02215, USA
    Depress Anxiety 28:333-41. 2011
    ..The present study sought to identify predictors of outcome for a comprehensive cognitive therapy (CT) developed for patients with obsessive-compulsive disorder (OCD)...
  20. ncbi request reprint Cognitive inhibition in trichotillomania and obsessive-compulsive disorder
    Antje Bohne
    Massachusetts General Hospital, Harvard Medical School, OCD Clinic, 9th Floor, 149 Thirteenth Street, Charlestown, MA 02129, USA
    Behav Res Ther 43:923-42. 2005
    ..In conclusion, although attention was disproportionately directed towards negative information in both disorders, cognitive inhibition deficits appeared specific to OCD...
  21. ncbi request reprint Cognitive-behavior therapy for self-injurious skin picking. A case series
    Thilo Deckersbach
    Harvard Medical School, Cognitive Behavior Therapy Program, Obsessive Compulsive Disorder Clinic, Psychiatric Neuroscience Program, Massachusetts General Hospital, USA
    Behav Modif 26:361-77. 2002
    ..In the current article, the authors describe the implementation and outcome of cognitive-behavior therapy for three patients with severe self-injurious skin picking, two of which had psychiatric comorbidity...
  22. ncbi request reprint Comorbid posttraumatic stress disorder: impact on treatment outcome for obsessive-compulsive disorder
    Beth S Gershuny
    OCD Clinic and Research Unit, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, 02129, USA
    Am J Psychiatry 159:852-4. 2002
    ..The study tested the effect of comorbid posttraumatic stress disorder (PTSD) on behavior therapy outcome for obsessive-compulsive disorder (OCD)...
  23. ncbi request reprint Prevalence of body dysmorphic disorder in a German college student sample
    Antje Bohne
    Massachusetts General Hospital East Harvard Medical School, OCD Clinic, 149 Thirteenth Street, Charlestown, MA 02129, USA
    Psychiatry Res 109:101-4. 2002
    ..One student with BDD also reported severe skin picking. In conclusion, BDD is a common psychiatric disorder in college students...
  24. ncbi request reprint The relationship between perceived social support and severity of body dysmorphic disorder symptoms: the role of gender
    Luana Marques
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Rev Bras Psiquiatr 33:238-44. 2011
    ..To address this gap in the literature, the present study aims to examine the association between three domains of perceived social support (i.e., family, friends, and significant others) and severity of body dysmorphic disorder symptoms...
  25. ncbi request reprint Habit reversal versus supportive psychotherapy in Tourette's disorder: a randomized controlled trial and predictors of treatment response
    Thilo Deckersbach
    OCD Clinic Psychiatric Neuroscience Division, Department of Psychiatry, 149 2611, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Behav Res Ther 44:1079-90. 2006
    ..Assessments of response inhibition may be of value for predicting treatment response to HR...
  26. doi request reprint Correlates of quality of life and functional disability in individuals with body dysmorphic disorder
    Luana Marques
    Massachusetts General Hospital Department of Psychiatry and Harvard Medical School, Boston, MA 02114, USA
    Psychosomatics 52:245-54. 2011
    ..The present study was designed to examine sociodemographic and clinical correlates of quality of life and disability (work, social, and family) in a sample of individuals with moderately severe BDD symptoms...
  27. ncbi request reprint Facial attractiveness ratings and perfectionism in body dysmorphic disorder and obsessive-compulsive disorder
    Ulrike Buhlmann
    Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, United States
    J Anxiety Disord 22:540-7. 2008
    ..These findings mostly support cognitive-behavioral models of BDD that suggest that individuals with BDD exhibit perfectionistic thinking and maladaptive attractiveness beliefs...
  28. doi request reprint Clinical considerations for the treatment of body dysmorphic disorder with cognitive-behavioral therapy
    Ulrike Buhlmann
    Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Body Image 5:39-49. 2008
    ..The aim of this review is to provide a treatment aid to clinicians by offering specific recommendations for improved care based on the available literature as well as our clinical experience...
  29. ncbi request reprint Dissociation between MEG alpha modulation and performance accuracy on visual working memory task in obsessive compulsive disorder
    Kristina T Ciesielski
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA
    Hum Brain Mapp 28:1401-14. 2007
    ....
  30. doi request reprint Reality monitoring in patients with body dysmorphic disorder
    Hannah E Reese
    Harvard University, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Behav Ther 42:387-98. 2011
    ..The results suggest that impairments in reality monitoring do not contribute to the development or maintenance of appearance-related beliefs in BDD...
  31. ncbi request reprint A study of parallel implicit and explicit information processing in patients with obsessive-compulsive disorder
    Thilo Deckersbach
    Department of Psychiatry, Massachusetts General Hospital East, Building 149, 13th Street, 9th Floor, Charlestown, MA 02129, USA
    Am J Psychiatry 159:1780-2. 2002
    ..Neuroimaging data suggest that during implicit learning, OCD patients use neural systems normally active during explicit learning to compensate for striatal dysfunction...
  32. doi request reprint Body dysmorphic symptoms: phenomenology and ethnicity
    Luana Marques
    Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Body Image 8:163-7. 2011
    ..Although most clinical features of BDD appear similar across ethnic groups, results showed some differences in body parts and behaviors between Caucasians and Asian Americans with BDD symptoms...
  33. doi request reprint Deficits in conditioned fear extinction in obsessive-compulsive disorder and neurobiological changes in the fear circuit
    Mohammed R Milad
    Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Charlestown 02129, USA
    JAMA Psychiatry 70:608-18; quiz 554. 2013
    ..Elevated fear and anxiety are common characteristics of this disorder. The neurobiology of fear regulation and consolidation of safety memories have not been examined in this patient population...
  34. ncbi request reprint Emotion recognition bias for contempt and anger in body dysmorphic disorder
    Ulrike Buhlmann
    Body Dysmorphic Disorder Clinic, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA
    J Psychiatr Res 40:105-11. 2006
    ..Perceiving others as rejecting might reinforce concerns about one's personal perceived ugliness and social desirability...
  35. ncbi request reprint A diffusion tensor imaging study of white matter in obsessive-compulsive disorder
    Paul A Cannistraro
    Psychiatric Neuroimaging Research Program, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    Depress Anxiety 24:440-6. 2007
    ..This could explain why surgically severing these tracts is therapeutic. Additional studies are needed to replicate these findings and to clarify their pathological and clinical significance...
  36. ncbi request reprint Body dysmorphic disorder and obsessive-compulsive disorder: similarities, differences and the classification debate
    Anne Chosak
    OCD and Related Disorders Program, Simches Research Building, Massachusetts General Hospital, 185 Cambridge Street, Boston MA 02114, USA
    Expert Rev Neurother 8:1209-18. 2008
    ..This article describes the association between obsessive-compulsive disorder and body dysmorphic disorder as evidenced by the emerging literature, and presents theoretical and clinical implications of this association...
  37. ncbi request reprint Is age at symptom onset associated with severity of memory impairment in adults with obsessive-compulsive disorder?
    A Henin
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129 2060, USA
    Am J Psychiatry 158:137-9. 2001
    ..Age at onset is a potentially important marker for neurobiological features of obsessive-compulsive disorder (OCD). This study examined the relationship between age at symptom onset and memory impairment in adults with OCD...
  38. pmc The phenomenology of self-reported body dysmorphic disorder by proxy
    Jennifer L Greenberg
    Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Body Image 10:243-6. 2013
    ..Most avoided social/occupational activities, including contact with the POC. The impact of BDDBP was profound, particularly on relationships. Findings may help elucidate diagnostic criteria, course, and treatment...
  39. doi request reprint Treatment utilization and barriers to treatment engagement among people with body dysmorphic symptoms
    Luana Marques
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    J Psychosom Res 70:286-93. 2011
    ..The present study sought to examine rates and patterns of treatment utilization as well as barriers to treatment among individuals with body dysmorphic symptoms...
  40. ncbi request reprint Physiologic responses to loud tones in individuals with obsessive-compulsive disorder
    Ulrike Buhlmann
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Psychosom Med 69:166-72. 2007
    ..To determine if individuals with obsessive-compulsive disorder (OCD) are characterized by larger eyeblink and/or autonomic responses to sudden, loud (startling) tones...
  41. ncbi request reprint Amygdala responses to human faces in obsessive-compulsive disorder
    Paul A Cannistraro
    Psychiatric Neuroimaging Research Program, Department of Psychiatry, Massachusetts General Hospital, Building 149, Thirteenth Street, Charlestown, MA 02129, USA
    Biol Psychiatry 56:916-20. 2004
    ..To assess the amygdala response to emotional faces in obsessive-compulsive disorder (OCD) using functional magnetic resonance imaging (fMRI)...
  42. ncbi request reprint The prevalence of body dysmorphic disorder: a population-based survey
    Winfried Rief
    Brigham and Women s Hospital Harvard Medical School, Boston, MA, USA
    Psychol Med 36:877-85. 2006
    ..Well designed studies on its prevalence and on base rates for diagnostic criteria are rare. Therefore this study aimed to reveal prevalence rates of BDD in the general population and to examine clinical features associated with BDD...
  43. ncbi request reprint Selective processing of emotional information in body dysmorphic disorder
    Ulrike Buhlmann
    University of Marburg, Germany
    J Anxiety Disord 16:289-98. 2002
    ..Results suggest that BDD may indeed be related to anxiety disorders such as social phobia...
  44. doi request reprint Facial asymmetry detection in patients with body dysmorphic disorder
    Hannah E Reese
    Harvard University, Cambridge, MA, USA
    Behav Res Ther 48:936-40. 2010
    ..Taken together, our results do not support a heightened perceptual ability or evaluative preference for symmetry among individuals with BDD...
  45. ncbi request reprint The Skin Picking Scale: scale construction and psychometric analyses
    N J Keuthen
    Department of Psychiatry, Massachusetts General Hospital, Charlestown, MA 02129 2060, USA
    J Psychosom Res 50:337-41. 2001
    ..This paper reports on the development of the Skin Picking Scale (SPS), a six-item paper-and-pencil measure for the assessment of skin picking...
  46. ncbi request reprint Strategic processing and episodic memory impairment in obsessive compulsive disorder
    C R Savage
    Department of Psychiatry, Massachusetts General Hospital, Charlestown 02129 2060, USA
    Neuropsychology 14:141-51. 2000
    ..Therefore, verbal and nonverbal episodic memory deficits in OCD are affected by impaired strategic processing. Results are consistent with neurobiological models proposing frontal-striatal system dysfunction in OCD...
  47. ncbi request reprint Expression of AE2 anion exchanger in mouse intestine
    S L Alper
    Molecular Medicine and Renal Units, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Am J Physiol 277:G321-32. 1999
    ..These localization studies will aid in the interpretation of anion exchanger function measured in epithelial sheets, isolated cells, and membrane vesicles...
  48. ncbi request reprint The Skin Picking Impact Scale (SPIS): scale development and psychometric analyses
    N J Keuthen
    Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown 02129 2060, USA
    Psychosomatics 42:397-403. 2001
    ..Sensitivity and specificity analyses indicate that a scale cutoff score of 7 optimally discriminates individuals with self-injurious skin picking from those with non-self-injurious skin picking...
  49. ncbi request reprint Barriers to treatment and service utilization in an internet sample of individuals with obsessive-compulsive symptoms
    Luana Marques
    Obsessive Compulsive and Related Disorders Program, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Depress Anxiety 27:470-5. 2010
    ..This study examined rates of treatment utilization and barriers to treatment in an internet sample of individuals with self-reported OCD...
  50. ncbi request reprint Emotion recognition deficits in body dysmorphic disorder
    Ulrike Buhlmann
    Department of Psychiatry, OCD Clinic, Massachusetts General Hospital and Harvard Medical School, 13th Street, Charlestown, MA 02129, USA
    J Psychiatr Res 38:201-6. 2004
    ..Perceiving others as angry and rejecting might reinforce concerns about one's personal ugliness and social desirability...
  51. ncbi request reprint Prevalence of body dysmorphic disorder in a community sample of women
    M W Otto
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Am J Psychiatry 158:2061-3. 2001
    ..In a large population-based study, the authors examined the prevalence and correlates of body dysmorphic disorder, a debilitating and chronic condition characterized by an imagined defect in appearance...
  52. doi request reprint Recent advances in research on cognition and emotion in OCD: a review
    Amanda W Calkins
    Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
    Curr Psychiatry Rep 15:357. 2013
    ..g., anxiety and disgust sensitivity) relate to the development and maintenance of OCD. We discuss the clinical implications of this research...
  53. doi request reprint Traumatic experiences in individuals with body dysmorphic disorder
    Ulrike Buhlmann
    Massachusetts General Hospital and Harvard Medical School, 185 Cambridge Street, Boston, MA 02114, USA
    J Nerv Ment Dis 200:95-8. 2012
    ..Surprisingly, there was no significant group difference in reports of emotional abuse in early life. This study provides preliminary evidence of the importance of examining abuse as a potential risk factor in the development of BDD...
  54. pmc Regulation of AE2-mediated Cl- transport by intracellular or by extracellular pH requires highly conserved amino acid residues of the AE2 NH2-terminal cytoplasmic domain
    A K Stewart
    Department of Medicine, Harvard Medical School, Molecular Medicine and Renal Units, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Gen Physiol 120:707-22. 2002
    ..Conserved, individual amino acid residues of the AE2 cytoplasmic domain contribute to independent regulation of anion exchange activity by pH(o) as well as pH(i)...
  55. pmc Dissociable genetic contributions to error processing: a multimodal neuroimaging study
    Yigal Agam
    Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America Athinoula A Martinos Center for Biomedical Imaging, Harvard Medical School, Charlestown, Massachusetts, United States of America
    PLoS ONE 9:e101784. 2014
    ..Here, we tested the hypothesis that these two error markers also have different genetic mediation...
  56. ncbi request reprint Anhedonia in obsessive-compulsive disorder: beyond comorbid depression
    Amitai Abramovitch
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA Electronic address
    Psychiatry Res 216:223-9. 2014
    ..Future research is needed to address the unique interface between anhedonia and reward responsiveness in OCD. Potential clinical implications are discussed. ..
  57. ncbi request reprint The cytoplasmic C-terminal fragment of polycystin-1 regulates a Ca2+-permeable cation channel
    D H Vandorpe
    Molecular Medicine and Renal Units, Beth Israel Deaconess Medical Center, Department of Medicine, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Biol Chem 276:4093-101. 2001
    ..Dysregulation of these or similar channels in autosomal dominant polycystic kidney disease may contribute to cyst formation or expansion...
  58. ncbi request reprint Perceived teasing experiences in body dysmorphic disorder
    Ulrike Buhlmann
    Massachusetts General Hospital and Harvard Medical School, Boston MA 02114, United States
    Body Image 4:381-5. 2007
    ..The group comprising individuals with BDD reported more appearance- and competency-related teasing than did control participants. This study provides preliminary evidence for the association between perceived teasing and BDD...
  59. pmc Body dysmorphic disorder: treating an underrecognized disorder
    Katharine A Phillips
    Butler Hospital, 345 Blackstone Blvd, Providence, RI 02906, USA
    Am J Psychiatry 165:1111-8. 2008
  60. ncbi request reprint Severe obsessive-compulsive disorder with and without body dysmorphic disorder: clinical correlates and implications
    S Evelyn Stewart
    McLean Hospital Obsessive Compulsive Disorder Institute, Belmont, MA, USA
    Ann Clin Psychiatry 20:33-8. 2008
    ..This exploratory study systematically examined prevalence and clinical correlates of Body Dysmorphic Disorder (BDD) comorbidity in an inpatient Obsessive-Compulsive Disorder (OCD) population...
  61. ncbi request reprint Do dysfunctional beliefs play a role in all types of obsessive-compulsive disorder?
    Steven Taylor
    Department of Psychiatry, University of British Columbia, 2255 Wesbrook Mall, Vancouver, BC V6T 2A1, Canada
    J Anxiety Disord 20:85-97. 2006
    ..These results are consistent with the view that dysfunctional beliefs may play a role in only some types of OCD...
  62. ncbi request reprint A critical evaluation of obsessive-compulsive disorder subtypes: symptoms versus mechanisms
    Dean McKay
    Department of Psychology, Fordham University, 441 East Fordham Road, Bronx, NY 10458 5198, USA
    Clin Psychol Rev 24:283-313. 2004
    ..The research is critically examined and implications for treatment are discussed. Recommendations for future investigations are offered...
  63. ncbi request reprint No disgust recognition deficit in obsessive-compulsive disorder
    Holly A Parker
    Department of Psychology, Harvard University, 33 Kirkland Street, Cambridge, MA 02138, USA
    J Behav Ther Exp Psychiatry 35:183-92. 2004
    ..Sprengelmeyer, Young, Pundt et al. (1997) reported a similar disgust recognition deficit in patients with obsessive-compulsive disorder (OCD)--an anxiety disorder associated with basal ganglia abnormality...
  64. ncbi request reprint Pathologic hairpulling, skin picking, and nail biting
    Antje Bohne
    Institute of Psychology I, University of Muenster, Muenster, Germany
    Ann Clin Psychiatry 17:227-32. 2005
    ..To date, HP, SP, and NB have received little attention in the psychiatric literature despite being widespread behaviors...

Research Grants10

  1. CBT Treatment Development for Body Dysmorphic Disorder
    Sabine Wilhelm; Fiscal Year: 2006
    ..abstract_text> ..
  2. COGNITIVE THERAPY IN OBSESSSIVE-COMPULSIVE DISORDER
    Sabine Wilhelm; Fiscal Year: 2002
    ..Using a combined sample of 30 patients we will study the influence of a small number of possible predictors of posttest outcome. ..
  3. Behavior Therapy for Adults with Tourette Syndrome
    Sabine Wilhelm; Fiscal Year: 2009
    ..The Informatics group at Yale University will provide data management services. ..
  4. Behavior Therapy for Adults with Tourette Syndrome
    Sabine Wilhelm; Fiscal Year: 2007
    ..The Informatics group at Yale University will provide data management services. ..
  5. Pharmacotherapy Prevention in Body Dysmorphic Disorder
    Sabine Wilhelm; Fiscal Year: 2007
    ..This study will yield unique and clinically important data, and will fill gaps in knowledge about this relatively common, severe, and understudied illness. ..
  6. Behavior Therapy for Adults with Tourette Syndrome
    Sabine Wilhelm; Fiscal Year: 2006
    ..The Informatics group at Yale University will provide data management services. ..
  7. Pharmacotherapy Prevention in Body Dysmorphic Disorder
    Sabine Wilhelm; Fiscal Year: 2006
    ..This study will yield unique and clinically important data, and will fill gaps in knowledge about this relatively common, severe, and understudied illness. ..
  8. Behavior Therapy for Adults with Tourette Syndrome
    Sabine Wilhelm; Fiscal Year: 2005
    ..The Informatics group at Yale University will provide data management services. ..
  9. Pharmacotherapy Relapse Prevention in Body Dysmorphic Disorder
    Sabine Wilhelm; Fiscal Year: 2009
    ..This study will yield unique and clinically important data, and will fill gaps in knowledge about this relatively common, severe, and understudied illness. ..