Research Topics
| Thomas J WhitfordSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Schizophrenia, myelination, and delayed corollary discharges: a hypothesisThomas J Whitford
Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, 1249 Boylston Street, Boston, MA 02215, USA
Schizophr Bull 38:486-94. 2012..The article concludes with a discussion of the implications of the theory and some testable predictions which may form a worthwhile basis for future research...
Corpus callosum abnormalities and their association with psychotic symptoms in patients with schizophreniaThomas J Whitford
Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
Biol Psychiatry 68:70-7. 2010....
Electrophysiological and diffusion tensor imaging evidence of delayed corollary discharges in patients with schizophreniaT J Whitford
Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, 1249 Boylston Street, Boston, MA 02215, USA
Psychol Med 41:959-69. 2011..The nature of these abnormalities is unknown. This study investigated whether SZ patients experience CDs that are abnormally delayed in their arrival at the sensory cortex...
Fiber geometry in the corpus callosum in schizophrenia: evidence for transcallosal misconnectionThomas J Whitford
Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Schizophr Res 132:69-74. 2011..Structural abnormalities in the callosal fibers connecting the heteromodal association areas of the prefrontal and temporoparietal cortices bilaterally have been suggested to play a role in the etiology of schizophrenia...
Hearing voices: a role of interhemispheric auditory connectivity?Christoph Mulert
Department of Psychiatry, Psychiatry Neuroimaging Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
World J Biol Psychiatry 13:153-8. 2012..Combining diffusion tensor imaging (DTI) and fibre tractography provides a unique opportunity to visualize and quantify entire fibre bundles...
Stochastic tractography study of Inferior Frontal Gyrus anatomical connectivity in schizophreniaMarek Kubicki
Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
Neuroimage 55:1657-64. 2011..However, due to technical challenges, anatomical connectivity abnormalities within this network and their involvement in clinical and cognitive deficits have not been studied...
Diffusion tensor imaging of anterior commissural fibers in patients with schizophreniaHongyoon Choi
Department of Psychiatry, Psychiatry Neuroimaging Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
Schizophr Res 130:78-85. 2011....
Predicting inter-hemispheric transfer time from the diffusion properties of the corpus callosum in healthy individuals and schizophrenia patients: a combined ERP and DTI studyThomas J Whitford
Psychiatry Neuroimaging Laboratory, Brigham and Women s Hospital, HarvardMedical School, Boston, MA 02215, USA
Neuroimage 54:2318-29. 2011..The present study investigated whether or not these IHTT abnormalities could be underpinned by structural damage to the visual fibers of the corpus callosum...
Longitudinal loss of gray matter volume in patients with first-episode schizophrenia: DARTEL automated analysis and ROI validationTakeshi Asami
Laboratory of Neuroscience, Clinical Neuroscience Division, Department of Psychiatry, Boston Veterans Affairs Healthcare System, Brockton Division, Harvard Medical School, Brockton, Massachusetts, USA
Neuroimage 59:986-96. 2012..Importantly, these reductions are directly associated with a worse clinical course. Congruence with ROI analyses suggests the promise of this longitudinal VBM methodology...
Abnormalities of middle longitudinal fascicle and disorganization in patients with schizophreniaTakeshi Asami
Laboratory of Neuroscience, Clinical Neuroscience Division, Department of Psychiatry, Boston Veterans Affairs Healthcare System, Brockton Division, Harvard Medical School, Brockton, MA, USA
Schizophr Res 143:253-9. 2013..While deficits of these functions are core clinical features of schizophrenia, no study has investigated the structural abnormalities of MdLF in schizophrenia...
Structural neuroimaging in schizophrenia: from methods to insights to treatmentsMartha E Shenton
Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, 1249 Boylston Street Boston, MA 02215, USA
Dialogues Clin Neurosci 12:317-32. 2010..We then review future prospects that need to be explored and pursued in order to translate our current knowledge into an understanding of the neurobiology of schizophrenia, which can then be translated into novel treatments...
