Thomas J Whitford

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Schizophrenia, myelination, and delayed corollary discharges: a hypothesis
    Thomas J Whitford
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, 1249 Boylston Street, Boston, MA 02215, USA
    Schizophr Bull 38:486-94. 2012
  2. pmc Corpus callosum abnormalities and their association with psychotic symptoms in patients with schizophrenia
    Thomas J Whitford
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    Biol Psychiatry 68:70-7. 2010
  3. pmc Electrophysiological and diffusion tensor imaging evidence of delayed corollary discharges in patients with schizophrenia
    T J Whitford
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, 1249 Boylston Street, Boston, MA 02215, USA
    Psychol Med 41:959-69. 2011
  4. pmc Fiber geometry in the corpus callosum in schizophrenia: evidence for transcallosal misconnection
    Thomas J Whitford
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Schizophr Res 132:69-74. 2011
  5. doi request reprint Hearing voices: a role of interhemispheric auditory connectivity?
    Christoph Mulert
    Department of Psychiatry, Psychiatry Neuroimaging Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    World J Biol Psychiatry 13:153-8. 2012
  6. pmc Abnormalities of middle longitudinal fascicle and disorganization in patients with schizophrenia
    Takeshi Asami
    Laboratory of Neuroscience, Clinical Neuroscience Division, Department of Psychiatry, Boston Veterans Affairs Healthcare System, Brockton Division, Harvard Medical School, Brockton, MA, USA
    Schizophr Res 143:253-9. 2013
  7. pmc Stochastic tractography study of Inferior Frontal Gyrus anatomical connectivity in schizophrenia
    Marek Kubicki
    Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Neuroimage 55:1657-64. 2011
  8. pmc Diffusion tensor imaging of anterior commissural fibers in patients with schizophrenia
    Hongyoon Choi
    Department of Psychiatry, Psychiatry Neuroimaging Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    Schizophr Res 130:78-85. 2011
  9. pmc Predicting inter-hemispheric transfer time from the diffusion properties of the corpus callosum in healthy individuals and schizophrenia patients: a combined ERP and DTI study
    Thomas J Whitford
    Psychiatry Neuroimaging Laboratory, Brigham and Women s Hospital, HarvardMedical School, Boston, MA 02215, USA
    Neuroimage 54:2318-29. 2011
  10. doi request reprint Globally and locally reduced MRI gray matter volumes in neuroleptic-naive men with schizotypal personality disorder: association with negative symptoms
    Takeshi Asami
    Laboratory of Neuroscience, Clinical Neuroscience Division, Department of Psychiatry, Boston Veterans Affairs Healthcare System, Brockton Division, Brockton, MA 02301, USA
    JAMA Psychiatry 70:361-72. 2013

Detail Information

Publications12

  1. pmc Schizophrenia, myelination, and delayed corollary discharges: a hypothesis
    Thomas J Whitford
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, 1249 Boylston Street, Boston, MA 02215, USA
    Schizophr Bull 38:486-94. 2012
    ..The article concludes with a discussion of the implications of the theory and some testable predictions which may form a worthwhile basis for future research...
  2. pmc Corpus callosum abnormalities and their association with psychotic symptoms in patients with schizophrenia
    Thomas J Whitford
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    Biol Psychiatry 68:70-7. 2010
    ....
  3. pmc Electrophysiological and diffusion tensor imaging evidence of delayed corollary discharges in patients with schizophrenia
    T J Whitford
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, 1249 Boylston Street, Boston, MA 02215, USA
    Psychol Med 41:959-69. 2011
    ..The nature of these abnormalities is unknown. This study investigated whether SZ patients experience CDs that are abnormally delayed in their arrival at the sensory cortex...
  4. pmc Fiber geometry in the corpus callosum in schizophrenia: evidence for transcallosal misconnection
    Thomas J Whitford
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Schizophr Res 132:69-74. 2011
    ..Structural abnormalities in the callosal fibers connecting the heteromodal association areas of the prefrontal and temporoparietal cortices bilaterally have been suggested to play a role in the etiology of schizophrenia...
  5. doi request reprint Hearing voices: a role of interhemispheric auditory connectivity?
    Christoph Mulert
    Department of Psychiatry, Psychiatry Neuroimaging Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    World J Biol Psychiatry 13:153-8. 2012
    ..Combining diffusion tensor imaging (DTI) and fibre tractography provides a unique opportunity to visualize and quantify entire fibre bundles...
  6. pmc Abnormalities of middle longitudinal fascicle and disorganization in patients with schizophrenia
    Takeshi Asami
    Laboratory of Neuroscience, Clinical Neuroscience Division, Department of Psychiatry, Boston Veterans Affairs Healthcare System, Brockton Division, Harvard Medical School, Brockton, MA, USA
    Schizophr Res 143:253-9. 2013
    ..While deficits of these functions are core clinical features of schizophrenia, no study has investigated the structural abnormalities of MdLF in schizophrenia...
  7. pmc Stochastic tractography study of Inferior Frontal Gyrus anatomical connectivity in schizophrenia
    Marek Kubicki
    Department of Psychiatry, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Neuroimage 55:1657-64. 2011
    ..However, due to technical challenges, anatomical connectivity abnormalities within this network and their involvement in clinical and cognitive deficits have not been studied...
  8. pmc Diffusion tensor imaging of anterior commissural fibers in patients with schizophrenia
    Hongyoon Choi
    Department of Psychiatry, Psychiatry Neuroimaging Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
    Schizophr Res 130:78-85. 2011
    ....
  9. pmc Predicting inter-hemispheric transfer time from the diffusion properties of the corpus callosum in healthy individuals and schizophrenia patients: a combined ERP and DTI study
    Thomas J Whitford
    Psychiatry Neuroimaging Laboratory, Brigham and Women s Hospital, HarvardMedical School, Boston, MA 02215, USA
    Neuroimage 54:2318-29. 2011
    ..The present study investigated whether or not these IHTT abnormalities could be underpinned by structural damage to the visual fibers of the corpus callosum...
  10. doi request reprint Globally and locally reduced MRI gray matter volumes in neuroleptic-naive men with schizotypal personality disorder: association with negative symptoms
    Takeshi Asami
    Laboratory of Neuroscience, Clinical Neuroscience Division, Department of Psychiatry, Boston Veterans Affairs Healthcare System, Brockton Division, Brockton, MA 02301, USA
    JAMA Psychiatry 70:361-72. 2013
    ..Thus, there is need for a whole-brain comparison to resolve inconsistencies and provide hitherto generally absent data on the association between GMV and symptoms...
  11. pmc Longitudinal loss of gray matter volume in patients with first-episode schizophrenia: DARTEL automated analysis and ROI validation
    Takeshi Asami
    Laboratory of Neuroscience, Clinical Neuroscience Division, Department of Psychiatry, Boston Veterans Affairs Healthcare System, Brockton Division, Harvard Medical School, Brockton, Massachusetts, USA
    Neuroimage 59:986-96. 2012
    ..Importantly, these reductions are directly associated with a worse clinical course. Congruence with ROI analyses suggests the promise of this longitudinal VBM methodology...
  12. pmc Structural neuroimaging in schizophrenia: from methods to insights to treatments
    Martha E Shenton
    Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women s Hospital, 1249 Boylston Street Boston, MA 02215, USA
    Dialogues Clin Neurosci 12:317-32. 2010
    ..We then review future prospects that need to be explored and pursued in order to translate our current knowledge into an understanding of the neurobiology of schizophrenia, which can then be translated into novel treatments...