Research Topics
Species | J WeuveSummaryAffiliation: Harvard University Country: USA Publications
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Publications
The effects of outpatient geriatric evaluation and management on caregiver burdenJ L Weuve
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
Gerontologist 40:429-36. 2000..7% vs 38.5%, p = .034). The findings suggest that GEM helps protect the informal caregivers of high-risk older people from the increases in burden that often accompany advancing age...
Exposure to phthalates in neonatal intensive care unit infants: urinary concentrations of monoesters and oxidative metabolitesJennifer Weuve
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
Environ Health Perspect 114:1424-31. 2006....- Physical activity, including walking, and cognitive function in older womenJennifer Weuve
Department of Epidemiology, Harvard School of Public Health, Boston, Mass 02215, USA
JAMA 292:1454-61. 2004..Physical activity may help maintain cognitive function in older adults... - Delta-aminolevulinic acid dehydratase polymorphism and the relation between low level lead exposure and the Mini-Mental Status Examination in older men: the Normative Aging StudyJ Weuve
Department of Environmental Health, Harvard School of Public Health, Landmark Center, Boston, MA 02215, USA
Occup Environ Med 63:746-53. 2006..To determine whether a polymorphism the in delta-aminolevulinic acid dehydratase (ALAD) gene modifies the neurotoxicity of lead in older adults... - High-sensitivity C-reactive protein and cognitive function in older womenJennifer Weuve
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Epidemiology 17:183-9. 2006..Inflammatory processes may be involved in the development of dementia, although findings from epidemiologic studies directly examining inflammatory markers and dementia or its precursor, impaired cognitive function, are inconsistent... - Lead burden and psychiatric symptoms and the modifying influence of the delta-aminolevulinic acid dehydratase (ALAD) polymorphism: the VA Normative Aging StudyPradeep Rajan
Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA
Am J Epidemiol 166:1400-8. 2007..004). These results augment evidence of a deleterious association between lead and psychiatric symptoms... - Modifying effects of the HFE polymorphisms on the association between lead burden and cognitive declineFlorence T Wang
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
Environ Health Perspect 115:1210-5. 2007..As iron and lead promote oxidative damage, and hemochromatosis (HFE) gene polymorphisms increase body iron burden, HFE variant alleles may modify the lead burden and cognitive decline relationship... - Use of di(2-ethylhexyl) phthalate-containing medical products and urinary levels of mono(2-ethylhexyl) phthalate in neonatal intensive care unit infantsRonald Green
Department of Environmental Health, Harvard School of Public Health, Boston, MA 02215, USA
Environ Health Perspect 113:1222-5. 2005..1 times those among infants in the low exposure group (p = 0.03). CONCLUSION: Intensive use of DEHP-containing medical devices in NICU infants results in higher exposure to DEHP as reflected by elevated urinary levels of MEHP... - Cumulative lead exposure and tooth loss in men: the normative aging studyManish Arora
Environmental and Occupational Medicine and Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
Environ Health Perspect 117:1531-4. 2009..Individuals previously exposed to lead remain at risk because of endogenous release of lead stored in their skeletal compartments. However, it is not known if long-term cumulative lead exposure is a risk factor for tooth loss... - Association of environmental cadmium exposure with periodontal disease in U.S. adultsManish Arora
Population Oral Health, Faculty of Dentistry, Westmead Centre for Oral Health, University of Sydney, Sydney, New South Wales, Australia
Environ Health Perspect 117:739-44. 2009..Cadmium adversely affects bone remodeling, and it is therefore possible that environmental Cd exposure may be a risk factor for periodontal-disease-related bone loss... - Cumulative exposure to lead in relation to cognitive function in older womenJennifer Weuve
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
Environ Health Perspect 117:574-80. 2009..Recent data indicate that chronic low-level exposure to lead is associated with accelerated declines in cognition in older age, but this has not been examined in women... 
Methodological challenges in causal research on racial and ethnic patterns of cognitive trajectories: measurement, selection, and biasM Maria Glymour
Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02115, USA
Neuropsychol Rev 18:194-213. 2008..For each, we describe how to recognize when such biases may be relevant and some possible analytic or design approaches to remediating these biases...- Interaction of the delta-aminolevulinic acid dehydratase polymorphism and lead burden on cognitive function: the VA normative aging studyPradeep Rajan
Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA
J Occup Environ Med 50:1053-61. 2008..We evaluated the modifying influence of a delta-aminolevulinic acid dehydratase (ALAD) polymorphism on the relation between lead burden and cognition among older men... - Association of environmental cadmium exposure with pediatric dental cariesManish Arora
Environmental and Occupational Medicine and Epidemiology, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02215, USA
Environ Health Perspect 116:821-5. 2008..Although animal experiments have shown that cadmium exposure results in severe dental caries, limited epidemiologic data are available on this issue... - Social ties and cognitive recovery after stroke: does social integration promote cognitive resilience?M Maria Glymour
Columbia University Mailman School of Public Health, New York, NY 10032, USA
Neuroepidemiology 31:10-20. 2008..Understanding this association may help us identify strategies to improve stroke recovery and help elucidate the etiology of dementia... - Cumulative community-level lead exposure and pulse pressure: the normative aging studyTodd Perlstein
Division of Cardiology, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Environ Health Perspect 115:1696-700. 2007..Lead accumulates in the vasculature and is associated with vascular oxidative stress, which can promote functional and structural vascular disease... - Breast cancer, birth cohorts, and Epstein-Barr virus: methodological issues in exploring the "hygiene hypothesis" in relation to breast cancer, Hodgkin's disease, and stomach cancerNancy Krieger
Department of Health and Social Behavior, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Cancer Epidemiol Biomarkers Prev 12:405-11. 2003..One methodological implication is that tests of the hygiene hypothesis must take into account birth cohort effects and age at incidence of the outcomes under study; age-standardized cross-sectional analyses may be misleading... - Postmenopausal hormone therapy and risk of cognitive decline in community-dwelling aging womenJae H Kang
Channing Lab, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Neurology 63:101-7. 2004..However, questions remain, including the effect of longer duration or of hormone therapy initiated at younger ages... - When is baseline adjustment useful in analyses of change? An example with education and cognitive changeM Maria Glymour
Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02215, USA
Am J Epidemiol 162:267-78. 2005..In some cases, change-score analyses without baseline adjustment provide unbiased causal effect estimates when baseline-adjusted estimates are biased... - Cadmium exposure in association with history of stroke and heart failureJunenette L Peters
Department of Environmental Health, Harvard School of Public Health, Landmark Center, P O Box 15697, 401 Park Drive, Boston, MA 02215, USA
Environ Res 110:199-206. 2010..It is unclear whether environmental cadmium exposure is associated with cardiovascular disease, although recent data suggest associations with myocardial infarction and peripheral arterial disease... - Serum total bilirubin level, prevalent stroke, and stroke outcomes: NHANES 1999-2004Todd S Perlstein
Department of Medicine, Cardiovascular Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
Am J Med 121:781-788.e1. 2008..Clinical data addressing the association of bilirubin with stroke are not available. We hypothesized that higher bilirubin levels would be associated with reduced stroke prevalence and improved stroke outcomes... - Maternal lead exposure and the secondary sex ratioJohn F Jarrell
Harvard School of Public Health, Harvard University, Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Hum Reprod 21:1901-6. 2006..A reduction in the secondary sex ratio may be associated with exposure to environmental toxicants. Little data exists relating this outcome to lead exposure, a well-known reproductive toxicant... - Red blood cell distribution width and mortality risk in a community-based prospective cohortTodd S Perlstein
Department of Medicine, Harvard Medical School, Brigham and Women s Hospital, Boston, MA 02115, USA
Arch Intern Med 169:588-94. 2009..It is unknown whether RDW is associated with mortality in the general population or whether this association is specific to CVD...