- Wnt signaling: relevance to beta-cell biology and diabetesHannah J Welters
Joslin Diabetes Center and Department of Medicine, Harvard Medical School, 1 Joslin Place, Boston, MA 02215, USA
Trends Endocrinol Metab 19:349-55. 2008..Together, these studies point towards a role for Wnt signaling in the pathogenesis of type 2 diabetes, highlighting the importance of further investigation of this pathway to develop new therapies for this disease...
- Molecular pathways underlying the pathogenesis of pancreatic alpha-cell dysfunctionDan Kawamori
Department of Cellular and Molecular Physiology, Joslin Diabetes Center, and Department of Medicine, Harvard Medical School, Boston, MA, USA
Adv Exp Med Biol 654:421-45. 2010..Therefore, understanding the molecular mechanism of how glucagon secretion is regulated is critical for treating the alpha-cell dysfunction observed in diabetes...