Roger Weiss

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Reasons for opioid use among patients with dependence on prescription opioids: The role of chronic pain
    Roger D Weiss
    McLean Hospital, 115 Mill St, Belmont, MA 02478, United States Harvard Medical School, 25 Shattuck St, Boston, MA, 02115, United States Electronic address
    J Subst Abuse Treat 47:140-5. 2014
  2. ncbi request reprint Who benefits from additional drug counseling among prescription opioid-dependent patients receiving buprenorphine-naloxone and standard medical management?
    Roger D Weiss
    McLean Hospital, Belmont, MA, United States Harvard Medical School, Boston, MA, United States Electronic address
    Drug Alcohol Depend 140:118-22. 2014
  3. pmc A multi-site, two-phase, Prescription Opioid Addiction Treatment Study (POATS): rationale, design, and methodology
    Roger D Weiss
    Division of Alcohol and Drug Abuse, McLean Hospital, 115 Mill Street, Belmont, MA 02478, United States
    Contemp Clin Trials 31:189-99. 2010
  4. ncbi request reprint Combining psychosocial treatment with pharmacotherapy for alcohol dependence
    Roger D Weiss
    Alcohol and Drug Abuse Treatment Program, McLean Hospital, Belmont, MA 02478, USA
    J Clin Psychopharmacol 26:S37-42. 2006
  5. ncbi request reprint Adherence to pharmacotherapy in patients with alcohol and opioid dependence
    Roger D Weiss
    Alcohol and Drug Abuse Treatment Program, McLean Hospital, Belmont, MA 02478 9106, USA
    Addiction 99:1382-92. 2004
  6. ncbi request reprint Treating patients with bipolar disorder and substance dependence: lessons learned
    Roger D Weiss
    Alcohol and Drug Abuse Treatment Program, McLean Hospital, Belmont, MA 02478, USA
    J Subst Abuse Treat 27:307-12. 2004
  7. ncbi request reprint The effect of 12-step self-help group attendance and participation on drug use outcomes among cocaine-dependent patients
    Roger D Weiss
    Department of Psychiatry, Harvard Medical School, Boston, MA 02115, USA
    Drug Alcohol Depend 77:177-84. 2005
  8. ncbi request reprint Group therapy for substance use disorders: what do we know?
    Roger D Weiss
    Department of Psychiatry, Harvard Medical School, MA, USA
    Harv Rev Psychiatry 12:339-50. 2004
  9. pmc A "community-friendly" version of integrated group therapy for patients with bipolar disorder and substance dependence: a randomized controlled trial
    Roger D Weiss
    Department of Psychiatry, Harvard Medical School, Boston, MA 02115, USA
    Drug Alcohol Depend 104:212-9. 2009
  10. ncbi request reprint Does recovery from substance use disorder matter in patients with bipolar disorder?
    Roger D Weiss
    Department of Psychiatry, Harvard Medical School, Boston, USA
    J Clin Psychiatry 66:730-5; quiz 808-9. 2005

Research Grants

Detail Information

Publications91

  1. ncbi request reprint Reasons for opioid use among patients with dependence on prescription opioids: The role of chronic pain
    Roger D Weiss
    McLean Hospital, 115 Mill St, Belmont, MA 02478, United States Harvard Medical School, 25 Shattuck St, Boston, MA, 02115, United States Electronic address
    J Subst Abuse Treat 47:140-5. 2014
    ..Results highlight the importance of physical pain as a reason for opioid use among patients with chronic pain. ..
  2. ncbi request reprint Who benefits from additional drug counseling among prescription opioid-dependent patients receiving buprenorphine-naloxone and standard medical management?
    Roger D Weiss
    McLean Hospital, Belmont, MA, United States Harvard Medical School, Boston, MA, United States Electronic address
    Drug Alcohol Depend 140:118-22. 2014
    ..However, research with other substance-dependent populations shows that subgroups of participants may benefit from a treatment although the entire population does not...
  3. pmc A multi-site, two-phase, Prescription Opioid Addiction Treatment Study (POATS): rationale, design, and methodology
    Roger D Weiss
    Division of Alcohol and Drug Abuse, McLean Hospital, 115 Mill Street, Belmont, MA 02478, United States
    Contemp Clin Trials 31:189-99. 2010
    ..POATS was developed to determine what benefit, if any, EMM offers over SMM in short-term and longer-term treatment paradigm. This paper describes the rationale and design of the study...
  4. ncbi request reprint Combining psychosocial treatment with pharmacotherapy for alcohol dependence
    Roger D Weiss
    Alcohol and Drug Abuse Treatment Program, McLean Hospital, Belmont, MA 02478, USA
    J Clin Psychopharmacol 26:S37-42. 2006
    ..Ongoing research examining the optimal combinations of medications with different psychosocial treatments for alcohol dependence may further inform the field...
  5. ncbi request reprint Adherence to pharmacotherapy in patients with alcohol and opioid dependence
    Roger D Weiss
    Alcohol and Drug Abuse Treatment Program, McLean Hospital, Belmont, MA 02478 9106, USA
    Addiction 99:1382-92. 2004
    ..This paper presents a review of issues related to medication adherence in patients with these substance use disorders...
  6. ncbi request reprint Treating patients with bipolar disorder and substance dependence: lessons learned
    Roger D Weiss
    Alcohol and Drug Abuse Treatment Program, McLean Hospital, Belmont, MA 02478, USA
    J Subst Abuse Treat 27:307-12. 2004
    ..Therapeutic aspects involved in addressing these themes are discussed...
  7. ncbi request reprint The effect of 12-step self-help group attendance and participation on drug use outcomes among cocaine-dependent patients
    Roger D Weiss
    Department of Psychiatry, Harvard Medical School, Boston, MA 02115, USA
    Drug Alcohol Depend 77:177-84. 2005
    ..Moreover, the distinction between attending meetings and actively participating in 12-step activities has not typically been examined...
  8. ncbi request reprint Group therapy for substance use disorders: what do we know?
    Roger D Weiss
    Department of Psychiatry, Harvard Medical School, MA, USA
    Harv Rev Psychiatry 12:339-50. 2004
    ..Unique methodological and logistical hurdles encountered in research on group therapy for substance use disorders, as well as considerations for future research, are also discussed...
  9. pmc A "community-friendly" version of integrated group therapy for patients with bipolar disorder and substance dependence: a randomized controlled trial
    Roger D Weiss
    Department of Psychiatry, Harvard Medical School, Boston, MA 02115, USA
    Drug Alcohol Depend 104:212-9. 2009
    ..This paper compares a briefer (12 session) version of integrated group therapy, led by substance use disorder counselors without previous cognitive-behavioral training or bipolar disorder experience, to group drug counseling...
  10. ncbi request reprint Does recovery from substance use disorder matter in patients with bipolar disorder?
    Roger D Weiss
    Department of Psychiatry, Harvard Medical School, Boston, USA
    J Clin Psychiatry 66:730-5; quiz 808-9. 2005
    ..To examine the potential impact of recovery from substance use disorder (SUD) on the course of bipolar disorder among patients diagnosed with both bipolar and substance use disorders according to DSM-IV criteria...
  11. ncbi request reprint A randomized trial of integrated group therapy versus group drug counseling for patients with bipolar disorder and substance dependence
    Roger D Weiss
    Department of Psychiatry, Harvard Medical School, Boston, and McLean Hospital, 115 Mill St, Belmont, MA 02478, USA
    Am J Psychiatry 164:100-7. 2007
    ..The authors hypothesized that patients receiving integrated group therapy would have fewer days of substance use and fewer weeks ill with bipolar disorder...
  12. pmc Conducting clinical research with prescription opioid dependence: defining the population
    Roger D Weiss
    Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, Massachusetts, USA
    Am J Addict 19:141-6. 2010
    ..The goal was to recruit a distinct but generalizable population of individuals dependent upon prescription opioids. (Am J Addict 2010;00:1-6)...
  13. pmc Do patients with alcohol dependence respond to placebo? Results from the COMBINE Study
    Roger D Weiss
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, and McLean Hospital, Belmont, Massachusetts, USA
    J Stud Alcohol Drugs 69:878-84. 2008
    ..The purpose of this study was to examine the nature of the effect of placebo medication plus accompanying medical management in the treatment of alcohol dependence...
  14. pmc Adjunctive counseling during brief and extended buprenorphine-naloxone treatment for prescription opioid dependence: a 2-phase randomized controlled trial
    Roger D Weiss
    Division of Alcohol and Drug Abuse, McLean Hospital, Belmont, MA 02478, USA
    Arch Gen Psychiatry 68:1238-46. 2011
    ..No randomized trials have examined treatments for prescription opioid dependence, despite its increasing prevalence...
  15. ncbi request reprint Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations
    Joel Gelernter
    Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    Hum Mol Genet 15:3498-507. 2006
    ..Functional studies of these loci are warranted. These results provide additional information useful in evaluating the many earlier discrepant findings regarding association of DRD2 with substance dependence...
  16. pmc Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample
    Lingjun Zuo
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA
    Neuropsychopharmacology 34:1504-13. 2009
    ..019). We conclude that two independent CNR1 variants have significant interaction effects on risk for CD in EAs; they may also have effects on risk for CD in AAs...
  17. ncbi request reprint Genomewide linkage scan for nicotine dependence: identification of a chromosome 5 risk locus
    Joel Gelernter
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Biol Psychiatry 61:119-26. 2007
    ..Nicotine dependence (ND) is costly to societies worldwide, moderately heritable, and genetically complex. Risk loci can be identified with genetic linkage analysis independent of prior physiological hypotheses...
  18. pmc Genomewide linkage scan for opioid dependence and related traits
    Joel Gelernter
    Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, West Haven, CT 06516, USA
    Am J Hum Genet 78:759-69. 2006
    ..These results are an initial step in identifying genes for opioid dependence on the basis of a genomewide investigation (i.e., a study not conditioned on prior physiological candidate-gene hypotheses)...
  19. ncbi request reprint Risk factors for cocaine-induced paranoia in cocaine-dependent sibling pairs
    Rasmon Kalayasiri
    Department of Psychiatry, Yale School of Medicine, New Haven, CT 06520, USA
    Drug Alcohol Depend 84:77-84. 2006
    ..Both environmental and genetic factors are thought to play a role, but the specific nature of such contributions is poorly understood...
  20. pmc HIV risk behavior in opioid dependent adults seeking detoxification treatment: an exploratory comparison of heroin and oxycodone users
    Christina S Meade
    McLean Hospital and Harvard Medical School, Belmont, Massachusetts, USA
    Am J Addict 18:289-93. 2009
    ..6%, p < .05). HIV prevention efforts should target both heroin and oxycodone users...
  21. pmc Additional treatment services in a cocaine treatment study: level of services obtained and impact on outcome
    Matthew Worley
    Department of Psychiatry, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Am J Addict 17:209-17. 2008
    ..The results suggest that during uncontrolled follow-up phases, additional non-protocol services may potentially confound the interpretation of treatment group comparisons in drug use outcomes...
  22. ncbi request reprint Pharmacotherapy for bipolar disorder and comorbid conditions: baseline data from STEP-BD
    Naomi M Simon
    Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychopharmacol 24:512-20. 2004
    ..Our findings highlight the need for greater clinical guidance and treatment options for patients with bipolar disorder and comorbidity...
  23. pmc A randomized trial of transcutaneous electric acupoint stimulation as adjunctive treatment for opioid detoxification
    Christina S Meade
    Harvard Medical School, Department of Psychiatry, Boston, MA 02115, USA
    J Subst Abuse Treat 38:12-21. 2010
    ..84, p < .01) over time. TEAS is an acceptable, inexpensive adjunctive treatment that is feasible to implement on an inpatient unit and may be a beneficial adjunct to pharmacological treatments for opioid detoxification...
  24. pmc Subtypes of major depression in substance dependence
    Mark J Niciu
    Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT 06030 2103, USA
    Addiction 104:1700-9. 2009
    ..Design  Secondary data analysis using pooled data from family-based and case-control genetic studies of SD...
  25. ncbi request reprint Validity of the distinction between primary and secondary substance use disorder in patients with bipolar disorder: data from the first 1000 STEP-BD participants
    Mark D Fossey
    Department of Psychiatry, University of Oklahoma College of Medicine Tulsa, Tulsa, Oklahoma 74135, USA
    Am J Addict 15:138-43. 2006
    ..The primary/secondary distinction for SUD is not valid when variations in the age of onset of the non-SUD are linked to course characteristics...
  26. pmc Impact of substance use disorders on recovery from episodes of depression in bipolar disorder patients: prospective data from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)
    Michael J Ostacher
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Am J Psychiatry 167:289-97. 2010
    ..The authors hypothesized that comorbid drug and alcohol use disorders would be associated with longer time to recovery in patients with bipolar disorder...
  27. ncbi request reprint The relationship between cocaine craving, psychosocial treatment, and subsequent cocaine use
    Roger D Weiss
    Department of Psychiatry, Harvard Medical School, Boston, MA 02478, USA
    Am J Psychiatry 160:1320-5. 2003
    ..This study examined the relationship between cocaine craving, psychosocial treatment, and cocaine use in the ensuing week...
  28. ncbi request reprint Intronic variants in the dopa decarboxylase (DDC) gene are associated with smoking behavior in European-Americans and African-Americans
    Yi Yu
    Department of Medicine, Genetics Program, Boston University School of Medicine, MA, USA
    Hum Mol Genet 15:2192-9. 2006
    ..These findings confirm a previous report of association of DDC with ND, localize the causative variants to the 3' end of the coding region and extend the association to multiple population groups...
  29. ncbi request reprint Assessing negative consequences in patients with substance use and bipolar disorders: psychometric properties of the short inventory of problems (SIP)
    Rachel E Bender
    Alcohol and Drug Abuse Treatment Program, McLean Hospital, Belmont, Massachusetts 02478, USA
    Am J Addict 16:503-9. 2007
    ..This modified version of the SIP was psychometrically sound, and may be useful in patients with both disorders. A greater understanding of perceived negative consequences may enhance outcome assessment in dually diagnosed populations...
  30. pmc Retrospective accounts of initial subjective effects of opioids in patients treated for pain who do or do not develop opioid addiction: a pilot case-control study
    Corey M Bieber
    Inflexxion, Inc, Newton, MA, USA
    Exp Clin Psychopharmacol 16:429-34. 2008
    ....
  31. pmc Does report of craving opioid medication predict aberrant drug behavior among chronic pain patients?
    Ajay D Wasan
    Department of Anesthesia, Pain Management Center, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Clin J Pain 25:193-8. 2009
    ..To examine the relationship between the self-report of craving prescription medication and subsequent opioid misuse among chronic pain patients prescribed opioids for pain...
  32. pmc Predictors of buprenorphine-naloxone dosing in a 12-week treatment trial for opioid-dependent youth: secondary analyses from a NIDA Clinical Trials Network study
    Amit Chakrabarti
    Division of Alcohol and Drug Abuse, McLean Hospital, Belmont, MA 02478, USA
    Drug Alcohol Depend 107:253-6. 2010
    ..The present investigation examines baseline patient characteristics to predict dosing of buprenorphine-naloxone, a promising treatment for opioid addiction in youths...
  33. pmc Association of psychiatric and substance use disorder comorbidity with cocaine dependence severity and treatment utilization in cocaine-dependent individuals
    Julian D Ford
    Department of Psychiatry, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT 06030 2103, United States
    Drug Alcohol Depend 99:193-203. 2009
    ..Results suggest that co-occurring substance dependence and psychiatric disorders warrant attention in cocaine dependence assessment, treatment, and self-help...
  34. pmc Predictors of dropout from group therapy among patients with bipolar and substance use disorders
    Fiona S Graff
    Department of Psychiatry, Harvard Medical School and McLean Hospital, 115 Mill Street, Belmont, MA 02478, United States
    Drug Alcohol Depend 94:272-5. 2008
    ..The current study identified baseline demographic and clinical characteristics that predict treatment dropout among patients with co-occurring bipolar and substance use disorders...
  35. ncbi request reprint Past anabolic-androgenic steroid use among men admitted for substance abuse treatment: an underrecognized problem?
    Gen Kanayama
    Alcohol and Drug Abuse Research Center, McLean Hospital, Belmont, Mass 02478, USA
    J Clin Psychiatry 64:156-60. 2003
    ..At present, however, little is known about prior AAS use among men entering inpatient substance abuse treatment...
  36. doi request reprint Focus on alcohol & drug abuse: ensuring validity in urine drug testing
    William B Jaffee
    McLean Hospital Alcohol and Drug Abuse Treatment Program, 115 Mill St, Belmont, MA 02478, USA
    Psychiatr Serv 59:140-2. 2008
    ....
  37. doi request reprint Physical pain and associated clinical characteristics in treatment-seeking patients in four substance use disorder treatment modalities
    Jennifer Sharpe Potter
    McLean Hospital, Belmont, Massachusetts 02478, USA jennifer
    Am J Addict 17:121-5. 2008
    ..43 (1.18-1.74)] and greater depressive symptoms [aOR = 1.30 (1.21-1.38)]. These findings support the presence of a sizable proportion of SUD patients with pain who may benefit from pain assessment as part of their SUD treatment...
  38. pmc Neurocognitive impairment in patients with co-occurring bipolar disorder and alcohol dependence upon discharge from inpatient care
    Boaz Levy
    Department of Psychiatry, Harvard Medical School McLean Hospital, Belmont, MA, USA
    Psychiatry Res 161:28-35. 2008
    ..Recognizing the extent of cognitive impairment in dually diagnosed patients may facilitate the effort to ameliorate their condition...
  39. pmc Neurocognitive impairment and psychosis in bipolar I disorder during early remission from an acute episode of mood disturbance
    Boaz Levy
    Department of Psychiatry, Harvard Medical School, McLean Hospital, 115 Mill St, Belmont, MA, 02478, USA
    J Clin Psychiatry 71:201-6. 2010
    ..The study aimed to determine whether the presence of psychosis during inpatient hospitalization was associated with greater cognitive impairment at the time of hospital discharge...
  40. pmc The course of substance use disorders in patients with borderline personality disorder and Axis II comparison subjects: a 10-year follow-up study
    Mary C Zanarini
    McLean Hospital, Belmont, MA 02478, USA
    Addiction 106:342-8. 2011
    ..The purpose of this study is to detail the course of substance use disorders (SUDs) over 10 years of prospective follow-up among patients with borderline personality disorder (BPD) and Axis II comparison subjects...
  41. pmc Ecologically valid support for the link between cognitive and psychosocial functioning in bipolar disorder
    Boaz Levy
    Mental Health Counseling, University of Massachusetts, Boston, MA USA
    Psychiatry Res 185:353-7. 2011
    ....
  42. pmc Pain and continued opioid use in individuals receiving buprenorphine-naloxone for opioid detoxification: secondary analyses from the Clinical Trials Network
    Jennifer Sharpe Potter
    Division of Alcohol and Drug Abuse, Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    J Subst Abuse Treat 38:S80-6. 2010
    ..These findings lend further support for continued research on pain among patients with opioid dependence...
  43. pmc Acceptability of drug testing in an outpatient substance abuse program for adolescents
    Sharon Levy
    Department of Pediatrics, Harvard Medical School, Boston, MA, USA
    J Adolesc Health 48:229-33. 2011
    ..Laboratory drug testing programs may be effective in reducing substance use by adolescents, but developmentally appropriate programs have not been described, and it is unknown if adolescents would be willing to participate in drug testing...
  44. pmc Depression precipitated by alcohol use in patients with co-occurring bipolar and substance use disorders
    William B Jaffee
    McLean Hospital Alcohol and Drug Abuse Treatment Program, Belmont, MA 01478, USA
    J Clin Psychiatry 70:171-6. 2009
    ..Thus, the present study tests whether alcohol use precipitates depression among patients with co-occurring bipolar disorder and substance use disorder...
  45. pmc Rapid cognitive screening of patients with substance use disorders
    Marc L Copersino
    Department of Psychiatry, Harvard Medical School and Division of Alcohol and Drug Use, McLean Hospital, Belmont, MA 02478, USA
    Exp Clin Psychopharmacol 17:337-44. 2009
    ..These findings indicate that the MoCA provides a time-efficient and resource-conscious way to identify patients with SUDs and neuropsychological impairment, thus addressing a critical need in the addiction treatment research community...
  46. pmc Measuring principal substance of abuse in comorbid patients for clinical research
    Margaret L Griffin
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Addict Behav 34:826-9. 2009
    ..Hence studies of comorbid patients may benefit from 1) using more than one method to assess principal substance and 2) reporting use of all substances as well as a targeted substance...
  47. pmc The duration of inpatient admission predicts cognitive functioning at discharge in patients with bipolar disorder
    Boaz Levy
    Department of Psychiatry, Harvard Medical School McLean Hospital, MA, USA
    Compr Psychiatry 50:322-6. 2009
    ..Findings from the current study may inform discharge planning for patients with bipolar disorder after an extended hospital stay...
  48. pmc A prospective study examining the effects of gender and sexual/physical abuse on mood outcomes in patients with co-occurring bipolar I and substance use disorders
    Christina S Meade
    Alcohol and Drug Abuse Treatment Program, McLean Hospital, Belmont, MA, USA
    Bipolar Disord 11:425-33. 2009
    ..This study prospectively examined gender differences in mood outcomes and tested the effects of sexual/physical abuse and posttraumatic stress disorder (PTSD)...
  49. pmc Chronic pain severity in opioid-dependent patients
    Jennifer S Potter
    McLean Hospital, Belmont, Massachusetts 02478, USA
    Am J Drug Alcohol Abuse 34:101-7. 2008
    ..The relationships were supported in a multivariate model. The results suggest it is feasible and important to assess for CP severity in SUD treatment settings...
  50. ncbi request reprint Is this urine really negative? A systematic review of tampering methods in urine drug screening and testing
    William B Jaffee
    McLean Hospital Alcohol and Drug Abuse Treatment Program, Belmont, MA 02478, USA
    J Subst Abuse Treat 33:33-42. 2007
    ....
  51. ncbi request reprint Domestic violence in women with PTSD and substance abuse
    Lisa M Najavits
    Trauma Research Program, Harvard Medical School, McLean Hospital, Proctor III, 115 Mill Street, Belmont, MA 02478, USA
    Addict Behav 29:707-15. 2004
    ..The complex dynamics of women as both recipients and enactors of negative relationship behaviors are discussed...
  52. ncbi request reprint Treatment utilization by women with PTSD and substance dependence
    Lisa M Najavits
    McLean Hospital, Belmont, Massachusetts, USA
    Am J Addict 13:215-24. 2004
    ..The most common treatments were individual therapy, medication, and hospitalization. Some treatments were perceived as harmful by some participants. The discussion addresses how to help patients obtain needed treatments...
  53. ncbi request reprint Seeking safety therapy for adolescent girls with PTSD and substance use disorder: a randomized controlled trial
    Lisa M Najavits
    Harvard Medical School, Boston, MA 02445, USA
    J Behav Health Serv Res 33:453-63. 2006
    ..Effect sizes were generally in the moderate to high range. Some gains were sustained at follow-up. SS appears a promising treatment for this population, but needs further study and perhaps additional clinical modification...
  54. ncbi request reprint Seeking Safety plus Exposure Therapy: an outcome study on dual diagnosis men
    Lisa M Najavits
    Harvard Medical School, Boston, Massachusetts, USA
    J Psychoactive Drugs 37:425-35. 2005
    ..Trends indicating improvement on 11 other outcome variables were also found. Treatment attendance, satisfaction, and alliance were extremely high. The need for further evaluation using more rigorous methodology is discussed...
  55. ncbi request reprint The relationship between educational attainment and relapse among alcohol-dependent men and women: a prospective study
    Shelly F Greenfield
    McLean Hospital, Belmont, MA 02478, USA
    Alcohol Clin Exp Res 27:1278-85. 2003
    ..We investigated the relationship between educational attainment and drinking outcomes after discharge from inpatient treatment for alcohol dependence...
  56. pmc Assessment of depressive symptom severity among patients with co-occurring bipolar disorder and substance dependence
    Monika E Kolodziej
    The Alcohol and Drug Abuse Treatment Program, McLean Hospital, 115 Mill Street, Belmont, MA 02478, United States
    J Affect Disord 106:83-9. 2008
    ....
  57. pmc HIV risk behavior among patients with co-occurring bipolar and substance use disorders: associations with mania and drug abuse
    Christina S Meade
    Department of Psychiatry, Harvard Medical School and McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Drug Alcohol Depend 92:296-300. 2008
    ..Bipolar and substance use disorders frequently co-occur, and both are associated with impulsivity, impaired judgment, and risk-taking...
  58. ncbi request reprint What general psychiatrists ask addiction psychiatrists: a review of 381 substance abuse consultations in a psychiatric hospital
    Shelly F Greenfield
    McLean Hospital, Belmont, Mass 02478, USA
    Am J Addict 12:18-28. 2003
    ..The findings indicate the potential utility of a substance abuse consultation service in a psychiatric hospital...
  59. ncbi request reprint Substance use histories in patients seeking treatment for controlled-release oxycodone dependence
    Jennifer Sharpe Potter
    McLean Hospital and Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA
    Drug Alcohol Depend 76:213-5. 2004
    ..8 versus illicit=15.8, P<0.05). These findings suggest that a history of substance abuse is common among patients abusing CR oxycodone, including individuals for whom CR oxycodone was initially legitimately prescribed for pain...
  60. ncbi request reprint History of abuse and drinking outcomes following inpatient alcohol treatment: a prospective study
    Shelly F Greenfield
    McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Drug Alcohol Depend 67:227-34. 2002
    ....
  61. ncbi request reprint Adherence to pharmacotherapy in bipolar disorder patients with and without co-occurring substance use disorders
    Sumita G Manwani
    Alcohol and Drug Abuse Treatment Program, McLean Hospital, Belmont, MA, USA
    J Clin Psychiatry 68:1172-6. 2007
    ..To examine patterns of adherence to mood stabilizers and reasons for nonadherence in patients with bipolar disorder, with and without substance use disorder (SUD)...
  62. ncbi request reprint Readability of patient handout materials in a nationwide sample of alcohol and drug abuse treatment programs
    Shelly F Greenfield
    The Alcohol and Drug Abuse Treatment Program, McLean Hospital, Belmont, MA 02478, USA
    Am J Addict 14:339-45. 2005
    ..Integrating knowledge regarding program materials' readability level and literacy levels of different populations could be successful aides to substance abuse treatment...
  63. ncbi request reprint Anxiety disorders among patients with co-occurring bipolar and substance use disorders
    Monika E Kolodziej
    The Alcohol and Drug Abuse Treatment Program, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Drug Alcohol Depend 80:251-7. 2005
    ..Our findings point to the importance of further investigating the ramifications of a trauma history among those who are dually diagnosed with bipolar and substance use disorders...
  64. ncbi request reprint Medical morbidity, mental illness, and substance use disorders
    Barbara Dickey
    Harvard Medical School and the Department of Psychiatry at Cambridge Hospital Cambridge, Massachusetts 02139, USA
    Psychiatr Serv 53:861-7. 2002
    ..The authors examined whether certain medical disorders are more prevalent among adults with severe mental illness and whether a comorbid substance use disorder increases prevalence beyond the effect of severe mental illness alone...
  65. pmc Adverse childhood events as risk factors for substance dependence: partial mediation by mood and anxiety disorders
    Kara R Douglas
    Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT 06030 2103, USA
    Addict Behav 35:7-13. 2010
    ..Adverse childhood events (ACEs) are associated with negative health outcomes. We examined ACEs as risk factors for substance dependence (SD) and the mediating effects of mood and anxiety disorders on the relations between ACEs and SD risk...
  66. ncbi request reprint The relationship between smoking and suicidal behavior, comorbidity, and course of illness in bipolar disorder
    Michael J Ostacher
    Massachusetts General Hospital, Bipolar Clinic and Research Program, Boston, MA 02114, USA
    J Clin Psychiatry 67:1907-11. 2006
    ..The purpose of this retrospective study was to examine the relationship between smoking, severity of bipolar disorder, suicidal behavior, and psychiatric and substance use disorder comorbidity...
  67. pmc Methods of recruiting adolescents with psychiatric and substance use disorders for a clinical trial
    William B Jaffee
    McLean Hospital, Harvard Medical School, Massachusetts, USA
    Am J Drug Alcohol Abuse 35:381-4. 2009
    ....
  68. ncbi request reprint Substance use and perceived symptom improvement among patients with bipolar disorder and substance dependence
    Roger D Weiss
    Alcohol and Drug Abuse Program, McLean Hospital, Belmont, MA, USA
    J Affect Disord 79:279-83. 2004
    ..We thus investigated reasons for substance use and perceived substance-induced improvement in BPD symptoms among patients with current BPD and substance dependence...
  69. ncbi request reprint Psychosocial treatments for cocaine dependence
    Grace O Leary Hennessy
    Alcohol and Drug Abuse Treatment Program, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Curr Psychiatry Rep 5:362-4. 2003
    ..A number of forms of psychosocial treatment for cocaine dependence have shown promising results, as detailed in the study descriptions...
  70. ncbi request reprint Challenges in the development of prescription opioid abuse-deterrent formulations
    Nathaniel P Katz
    Tufts University School of Medicine, Boston, MA, USA
    Clin J Pain 23:648-60. 2007
    ....
  71. pmc Substance dependence low-density whole genome association study in two distinct American populations
    Yi Yu
    Department of Medicine Genetics Program, Boston University Schools of Medicine and Public Health, Boston, MA, USA
    Hum Genet 123:495-506. 2008
    ..Our study provides an initial substance dependence trait-specific blueprint of associated regions for future candidate gene studies...
  72. pmc Correlates of co-occurring ADHD in drug-dependent subjects: prevalence and features of substance dependence and psychiatric disorders
    Albert J Arias
    Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT 06030, USA
    Addict Behav 33:1199-207. 2008
    ..We examined the prevalence and course of psychiatric and substance dependence (SD) disorders in subjects with SD and attention deficit hyperactivity disorder (ADHD)...
  73. pmc Association of variants in MANEA with cocaine-related behaviors
    Lindsay A Farrer
    Genetics Program, Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Arch Gen Psychiatry 66:267-74. 2009
    ....
  74. pmc Alterations in brain structure and functional connectivity in prescription opioid-dependent patients
    Jaymin Upadhyay
    P A I N Group, Harvard Medical School, c o Brain Imaging Centre, McLean Hospital, Department of Psychiatry, 115 Mill Street, Belmont, MA 02478 9106, USA
    Brain 133:2098-114. 2010
    ..These results may have important clinical implications for uncovering the effects of long-term prescription opioid use on brain structure and function...
  75. ncbi request reprint Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia
    Joel Gelernter
    Yale University School of Medicine, Department of Psychiatry, Division of Human Genetics and VA CT Healthcare Center, West Haven, CT 06516, USA
    Am J Med Genet B Neuropsychiatr Genet 136:45-52. 2005
    ..35 for membership in the "Moderate Cocaine and Opioid Abuse" cluster on chromosome 18. These results provide a basis for the identification of specific genes contributing to risk for these traits...
  76. ncbi request reprint Mediators of outcome of psychosocial treatments for cocaine dependence
    Paul Crits-Christoph
    Department of Psychiatry, University of Pennsylvania, PA, USA
    J Consult Clin Psychol 71:918-25. 2003
    ..In addition, a measure of beliefs about addiction developed to test mediation of outcome of cognitive therapy was found to correlate moderately with drug use outcomes in both cognitive therapy and individual drug counseling...
  77. pmc Pro-opiomelanocortin gene variation related to alcohol or drug dependence: evidence and replications across family- and population-based studies
    Huiping Zhang
    Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06516, USA
    Biol Psychiatry 66:128-36. 2009
    ..The pro-opiomelanocortin gene (POMC) encodes several peptides important for endogenous opioidergic neurotransmission. We tested whether POMC genetic variation affects risk for substance dependence...
  78. pmc Dense genomewide linkage scan for alcohol dependence in African Americans: significant linkage on chromosome 10
    Joel Gelernter
    Department of Psychiatry, Division of Human Genetics, Yale University School of Medicine, New Haven, CT, USA
    Biol Psychiatry 65:111-5. 2009
    ..Risk loci in several populations have been identified with genetic linkage analysis. To date, there has been no published linkage study of AD focused on African Americans (AAs)...
  79. ncbi request reprint A review of brief medication-adherence instruments used in patients with schizophrenia and bipolar disorder
    Brian Pomykacz
    Harv Rev Psychiatry 15:259-63. 2007
  80. ncbi request reprint Limiting inpatient substance use treatment: what are the consequences?
    Barbara Dickey
    Cambridge Hospital, USA
    Med Care Res Rev 60:332-46. 2003
    ..There was no evidence of cost shifting. Although emphasis on outpatient treatment did not result in cost shifting, the combination of substance use disorder and psychiatric illness remains an expensive public health problem...
  81. pmc Cost and cost-effectiveness of the COMBINE study in alcohol-dependent patients
    Gary A Zarkin
    RTI International, 3040 Cornwallis Rd, Research Triangle Park, NC 27709, USA
    Arch Gen Psychiatry 65:1214-21. 2008
    ..The costs and cost-effectiveness of these combinations are unknown and of interest to clinicians and policy makers...
  82. pmc Response: providing relief, avoiding euphoria
    Dennis Paul
    Addict Sci Clin Pract 4:26-7. 2008
  83. ncbi request reprint Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial
    Raymond F Anton
    Center for Drug and Alcohol Programs, Medical University of South Carolina, Charleston 29425, USA
    JAMA 295:2003-17. 2006
    ..Alcohol dependence treatment may include medications, behavioral therapies, or both. It is unknown how combining these treatments may impact their effectiveness, especially in the context of primary care and other nonspecialty settings...
  84. ncbi request reprint Treatment of patients with substance use disorders, second edition. American Psychiatric Association
    Herbert D Kleber
    Am J Psychiatry 164:5-123. 2007
  85. ncbi request reprint Self-harm and suicidal behavior in women with comorbid PTSD and substance dependence
    Melanie S Harned
    Department of Psychology, University of Washington, Seattle, Washington 98195 5125, USA
    Am J Addict 15:392-5. 2006
    ..Women who had and had not engaged in such behavior differed in SD diagnoses and reasons for staying safe, but not in the number or type of traumatic experiences, age at first trauma, or substance abuse diagnoses...
  86. ncbi request reprint Addressing substance abuse in health care settings
    William R Miller
    University of Mexico Center on Alcoholism, Substance Abuse and Addictions CASAA
    Alcohol Clin Exp Res 30:292-302. 2006
    ..Compton; and (7) Interventions for Heavy Drinking in Health Care settings: Barriers and Strategies, by Mark L. Willenbring...
  87. pmc Improving the care of individuals with schizophrenia and substance use disorders: consensus recommendations
    Douglas M Ziedonis
    University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, 675 Hoes Lane, Rm D 349, Piscataway, NJ 08854, USA
    J Psychiatr Pract 11:315-39. 2005
    ..An algorithm summarizing the consensus recommendations is provided in an appendix...
  88. pmc The validity of cocaine dependence subtypes
    Henry R Kranzler
    Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT 06030 2103, United States
    Addict Behav 33:41-53. 2008
    ..These findings support the validity of the methods used to derive homogeneous subgroups of CD subjects and the resulting CD subtypes. Independent replication of these findings would provide further validation of this approach...
  89. ncbi request reprint Treatment of patients with substance use disorders, second edition. American Psychiatic Association
    Herbert D Kleber
    Am J Psychiatry 163:5-82. 2006
  90. ncbi request reprint The Michigan Alcoholism Screening Test and its shortened form: a meta-analytic inquiry into score reliability
    Alan L Shields
    East Tennessee State University, Johnson City, Tennessee 37614 1702, USA
    Subst Use Misuse 42:1783-800. 2007
    ..Multiple regression equations provide practical guidelines to improve reliability estimates for the future use of these instruments...
  91. ncbi request reprint Improvement of physical health and quality of life of alcohol-dependent individuals with topiramate treatment: US multisite randomized controlled trial
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908 0623, USA
    Arch Intern Med 168:1188-99. 2008
    ..We sought to determine whether topiramate's antidrinking effects are bolstered by improvements in physical and psychosocial well-being...

Research Grants16

  1. Modifying Group Therapy for Bipolar Abusers
    Roger Weiss; Fiscal Year: 2006
    ..If warranted by the results, effect sizes from the proposed study will be used to help in the preparation of a larger-scale subsequent Stage II study. ..
  2. Modifying Group Therapy for Bipolar Abusers
    Roger Weiss; Fiscal Year: 2004
    ..If warranted by the results, effect sizes from the proposed study will be used to help in the preparation of a larger-scale subsequent Stage II study. ..
  3. Modifying Group Therapy for Bipolar Abusers
    Roger Weiss; Fiscal Year: 2004
    ..If warranted by the results, effect sizes from the proposed study will be used to help in the preparation of a larger-scale subsequent Stage II study. ..
  4. Modifying Group Therapy for Bipolar Abusers
    Roger Weiss; Fiscal Year: 2003
    ..If warranted by the results, effect sizes from the proposed study will be used to help in the preparation of a larger-scale subsequent Stage II study. ..
  5. RELAPSE PREVENTION GROUP FOR BIPOLAR SUBSTANCE ABUSERS
    Roger Weiss; Fiscal Year: 2001
    ....
  6. RELAPSE PREVENTION GROUP FOR BIPOLAR SUBSTANCE ABUSERS
    Roger Weiss; Fiscal Year: 2000
    ....
  7. RELAPSE PREVENTION GROUP FOR BIPOLAR SUBSTANCE ABUSERS
    Roger Weiss; Fiscal Year: 1999
    ....
  8. Modifying Group Therapy for Bipolar Abusers
    Roger Weiss; Fiscal Year: 2005
    ..If warranted by the results, effect sizes from the proposed study will be used to help in the preparation of a larger-scale subsequent Stage II study. ..
  9. Modifying Group Therapy for Bipolar Abusers
    Roger Weiss; Fiscal Year: 2002
    ..If warranted by the results, effect sizes from the proposed study will be used to help in the preparation of a larger-scale subsequent Stage II study. ..