Jane C Weeks

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint The impact of tumor progesterone receptor status on optimal adjuvant endocrine therapy for postmenopausal patients with early-stage breast cancer: a decision analysis
    Rinaa S Punglia
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Cancer 106:2576-82. 2006
  2. pmc Patients' expectations about effects of chemotherapy for advanced cancer
    Jane C Weeks
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02215, USA
    N Engl J Med 367:1616-25. 2012
  3. pmc Early dissemination of bevacizumab for advanced colorectal cancer: a prospective cohort study
    S Yousuf Zafar
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, NC, USA
    BMC Cancer 11:354. 2011
  4. ncbi request reprint Short-term quality-of-life outcomes following laparoscopic-assisted colectomy vs open colectomy for colon cancer: a randomized trial
    Jane C Weeks
    Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    JAMA 287:321-8. 2002
  5. pmc Underuse of hospice care by Medicaid-insured patients with stage IV lung cancer in New York and California
    Jennifer W Mack
    Dana Farber Cancer Institute, 450 Brookline Ave, Boston, MA 02215, USA
    J Clin Oncol 31:2569-79. 2013
  6. pmc Institutional variation in the surgical treatment of breast cancer: a study of the NCCN
    Caprice C Greenberg
    Center for Outcomes and Policy Research, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    Ann Surg 254:339-45. 2011
  7. pmc Factors associated with pain among ambulatory patients with cancer with advanced disease at a comprehensive cancer center
    Sherri O Stuver
    Dana Farber Cancer Institute, Boston, MA 02215, USA
    J Oncol Pract 8:e17-23. 2012
  8. pmc Patients' experiences with care for lung cancer and colorectal cancer: findings from the Cancer Care Outcomes Research and Surveillance Consortium
    John Z Ayanian
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, MA 02115, USA
    J Clin Oncol 28:4154-61. 2010
  9. pmc Variation in the utilization of reconstruction following mastectomy in elderly women
    Haejin In
    Center for Surgery and Public Health, Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
    Ann Surg Oncol 20:1872-9. 2013
  10. pmc Associations between end-of-life discussion characteristics and care received near death: a prospective cohort study
    Jennifer W Mack
    Dana Farber Cancer Institute, Boston, MA 02215, USA
    J Clin Oncol 30:4387-95. 2012

Research Grants

Collaborators

Detail Information

Publications116 found, 100 shown here

  1. ncbi request reprint The impact of tumor progesterone receptor status on optimal adjuvant endocrine therapy for postmenopausal patients with early-stage breast cancer: a decision analysis
    Rinaa S Punglia
    Department of Radiation Oncology, Dana Farber Cancer Institute and Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Cancer 106:2576-82. 2006
    ..However, the optimal sequencing of AIs and tamoxifen as adjuvant therapy is not known and may differ for biologic subsets of cancers...
  2. pmc Patients' expectations about effects of chemotherapy for advanced cancer
    Jane C Weeks
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02215, USA
    N Engl J Med 367:1616-25. 2012
    ..Chemotherapy for metastatic lung or colorectal cancer can prolong life by weeks or months and may provide palliation, but it is not curative...
  3. pmc Early dissemination of bevacizumab for advanced colorectal cancer: a prospective cohort study
    S Yousuf Zafar
    Division of Medical Oncology, Department of Medicine, Duke University Medical Center, Durham, NC, USA
    BMC Cancer 11:354. 2011
    ..We describe early dissemination patterns for first-line bevacizumab given for metastatic colorectal cancer treatment...
  4. ncbi request reprint Short-term quality-of-life outcomes following laparoscopic-assisted colectomy vs open colectomy for colon cancer: a randomized trial
    Jane C Weeks
    Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    JAMA 287:321-8. 2002
    ..The safety and efficacy of LAC for colon cancer are unknown, and the nature and magnitude of any quality-of-life (QOL) benefit resulting from LAC for colon cancer is also unknown...
  5. pmc Underuse of hospice care by Medicaid-insured patients with stage IV lung cancer in New York and California
    Jennifer W Mack
    Dana Farber Cancer Institute, 450 Brookline Ave, Boston, MA 02215, USA
    J Clin Oncol 31:2569-79. 2013
    ..Medicare patients with advanced cancer have low rates of hospice use. We sought to evaluate hospice use among patients in Medicaid, which insures younger and indigent patients, relative to those in Medicare...
  6. pmc Institutional variation in the surgical treatment of breast cancer: a study of the NCCN
    Caprice C Greenberg
    Center for Outcomes and Policy Research, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    Ann Surg 254:339-45. 2011
    ..To investigate the relationship between supply of subspecialty care and type of procedure preferentially performed for early stage breast cancer...
  7. pmc Factors associated with pain among ambulatory patients with cancer with advanced disease at a comprehensive cancer center
    Sherri O Stuver
    Dana Farber Cancer Institute, Boston, MA 02215, USA
    J Oncol Pract 8:e17-23. 2012
    ..To better understand the burden of pain among patients with advanced cancer, we examined the prevalence of pain reported during office and treatment visits...
  8. pmc Patients' experiences with care for lung cancer and colorectal cancer: findings from the Cancer Care Outcomes Research and Surveillance Consortium
    John Z Ayanian
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, MA 02115, USA
    J Clin Oncol 28:4154-61. 2010
    ..To assess patients' experiences with cancer care, ratings of their quality of care, and correlates of these assessments...
  9. pmc Variation in the utilization of reconstruction following mastectomy in elderly women
    Haejin In
    Center for Surgery and Public Health, Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
    Ann Surg Oncol 20:1872-9. 2013
    ..However, actual use of reconstruction decreases with increasing age. Whereas this may reflect patient preference and clinical factors, it may also represent age-based disparity...
  10. pmc Associations between end-of-life discussion characteristics and care received near death: a prospective cohort study
    Jennifer W Mack
    Dana Farber Cancer Institute, Boston, MA 02215, USA
    J Clin Oncol 30:4387-95. 2012
    ..We sought to evaluate the extent to which EOL discussion characteristics, such as timing, involved providers, and location, are associated with the aggressiveness of care received near death...
  11. pmc Measuring clinically significant chemotherapy-related toxicities using Medicare claims from Cancer and Leukemia Group B (CALGB) trial participants
    Elizabeth B Lamont
    Massachusetts General Hospital, Boston, Massachusetts, USA
    Med Care 46:303-8. 2008
    ..Because the elderly are underrepresented on clinical trials, physicians have few sources of information to estimate the risks (ie, toxicities) and benefits of chemotherapy administration to the elderly...
  12. pmc Chemotherapy use for hormone receptor-positive, lymph node-negative breast cancer
    Michael J Hassett
    Department of Medical Oncology, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    J Clin Oncol 26:5553-60. 2008
    ....
  13. ncbi request reprint Racial differences in definitive breast cancer therapy in older women: are they explained by the hospitals where patients undergo surgery?
    Nancy L Keating
    Division of General Internal Medicine, Department of Medicine, Brigham and Women s Hospital, 180 Longwood Avenue, Boston, MA 02115, USA
    Med Care 47:765-73. 2009
    ..Prior research has documented racial disparities in patterns of care and outcomes for women with breast cancer...
  14. pmc Expectations about the effectiveness of radiation therapy among patients with incurable lung cancer
    Aileen B Chen
    Dana Farber Cancer Institute, 450 Brookline Ave, D1111, Boston, MA 02215, USA
    J Clin Oncol 31:2730-5. 2013
    ..Although radiation therapy (RT) can palliate symptoms and may prolong life, it is not curative for patients with metastatic lung cancer. We investigated patient expectations about the goals of RT for incurable lung cancers...
  15. doi request reprint Comparative effectiveness of three platinum-doublet chemotherapy regimens in elderly patients with advanced non-small cell lung cancer
    Junya Zhu
    Center for Patient Safety, Dana Farber Cancer Institute, Boston, MA 02215, USA
    Cancer 119:2048-60. 2013
    ..Their relative effectiveness and comparability based on squamous versus nonsquamous histology is uncertain...
  16. pmc Regional variation in spending and survival for older adults with advanced cancer
    Gabriel A Brooks
    Dana Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA
    J Natl Cancer Inst 105:634-42. 2013
    ..Medicare spending varies substantially across the United States. We evaluated the association between mean regional spending and survival in advanced cancer...
  17. pmc Chapter 9: The MGH-HMS lung cancer policy model: tobacco control versus screening
    Pamela M McMahon
    Institute for Technology Assessment, Massachusetts General Hospital, 101 Merrimac Street, Boston, MA 02114, USA
    Risk Anal 32:S117-24. 2012
    ..0% (42.0% in men, 33.3% in women). The adoption of annual screening would have prevented less than half as many lung cancer deaths as the elimination of cigarette smoking...
  18. doi request reprint Peace of mind and sense of purpose as core existential issues among parents of children with cancer
    Jennifer W Mack
    Department of Medicine, Children s Hospital, Boston, Massachusetts, USA
    Arch Pediatr Adolesc Med 163:519-24. 2009
    ..To evaluate issues experienced by parents of children with cancer and factors related to parents' ability to find peace of mind...
  19. pmc Factors associated with guideline-concordant use of radiotherapy after mastectomy in the national comprehensive cancer network
    Rinaa S Punglia
    Dana Farber Cancer Institute, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 72:1434-40. 2008
    ....
  20. pmc Time to diagnosis and breast cancer stage by race/ethnicity
    Erica T Warner
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    Breast Cancer Res Treat 136:813-21. 2012
    ..Longer time to diagnosis did not fully explain differences in stage between racial/ethnicity groups...
  21. pmc Cancer patients' roles in treatment decisions: do characteristics of the decision influence roles?
    Nancy L Keating
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 28:4364-70. 2010
    ..Younger and better educated patients have more active roles in decisions, but whether patients' roles in decisions differ by characteristics of the decision itself is unknown...
  22. pmc Looking beyond where children die: determinants and effects of planning a child's location of death
    Veronica Dussel
    Center for Outcomes and Policy Research, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Pain Symptom Manage 37:33-43. 2009
    ..Opportunity to plan LOD is associated with outcomes consistent with high-quality palliative care, even among nonhome deaths, and thus may represent a more relevant outcome than actual LOD...
  23. pmc The effect of age on delay in diagnosis and stage of breast cancer
    Ann H Partridge
    Dana Farber Cancer Institute, 450 Brookline Avenue, Boston, Massachusetts 02115, USA
    Oncologist 17:775-82. 2012
    ..We sought to examine the relationship among young age (≤40 years), the likelihood of a delay in diagnosis, and stage...
  24. doi request reprint Considerations about hastening death among parents of children who die of cancer
    Veronica Dussel
    Center for Outcomes and Policy Research and Department of Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    Arch Pediatr Adolesc Med 164:231-7. 2010
    ....
  25. pmc Pharmacogenomic variation of CYP2D6 and the choice of optimal adjuvant endocrine therapy for postmenopausal breast cancer: a modeling analysis
    Rinaa S Punglia
    Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women s Hospital, 44 Binney St, Boston, MA 02115, USA
    J Natl Cancer Inst 100:642-8. 2008
    ....
  26. pmc Use of adjuvant trastuzumab in women with human epidermal growth factor receptor 2 (HER2)-positive breast cancer by race/ethnicity and education within the National Comprehensive Cancer Network
    Rachel A Freedman
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA
    Cancer 119:839-46. 2013
    ..The authors of this report examined receipt and completion of adjuvant trastuzumab by race/ethnicity and education for women with HER2-positive disease...
  27. doi request reprint A longitudinal study of pain variability and its correlates in ambulatory patients with advanced stage cancer
    Junya Zhu
    Center for Patient Safety, Dana Farber Cancer Institute, Boston, Massachusetts 02215 5450, USA
    Cancer 118:6278-86. 2012
    ....
  28. pmc The role of National Cancer Institute-designated cancer center status: observed variation in surgical care depends on the level of evidence
    Haejin In
    Center for Surgery and Public Health, Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
    Ann Surg 255:890-5. 2012
    ..We sought to evaluate differences in guideline concordance between National Cancer Institute (NCI)-designated and other centers and determine whether the level of available evidence influences the degree of variation in concordance...
  29. ncbi request reprint Evaluating claims-based indicators of the intensity of end-of-life cancer care
    Craig C Earle
    Division of Population Sciences, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Int J Qual Health Care 17:505-9. 2005
    ..To evaluate measures that could use existing administrative data to assess the intensity of end-of-life cancer care...
  30. pmc Aggressiveness of cancer care near the end of life: is it a quality-of-care issue?
    Craig C Earle
    Division of Population Sciences, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    J Clin Oncol 26:3860-6. 2008
    ..Whether the concept of overly aggressive treatment represents a quality-of-care issue that is acceptable to all involved stakeholders is an open question...
  31. pmc End-of-life care discussions among patients with advanced cancer: a cohort study
    Jennifer W Mack
    Dana Farber Cancer Institute, Children s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Ann Intern Med 156:204-10. 2012
    ..National guidelines recommend that physicians discuss end-of-life (EOL) care planning with patients with cancer whose life expectancy is less than 1 year...
  32. pmc Representativeness of participants in the cancer care outcomes research and surveillance consortium relative to the surveillance, epidemiology, and end results program
    Paul J Catalano
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, Boston, MA 02215 5450, USA
    Med Care 51:e9-15. 2013
    ..As CanCORS results will inform national policy, it is important to know how they generalize to the United States population with these cancers...
  33. pmc High-cost imaging in elderly patients with stage IV cancer
    Yue Yung Hu
    Center for Surgery and Public Health, Department of Surgery, Brigham and Women s Hospital, Boston, MA, USA
    J Natl Cancer Inst 104:1164-72. 2012
    ..We sought to determine recent and long-term patterns in high-cost diagnostic imaging use among elderly (aged ≥65 years) patients with stage IV cancer...
  34. pmc Cost-effectiveness of computed tomography screening for lung cancer in the United States
    Pamela M McMahon
    Institute for Technology Assessment, Massachusetts General Hospital, Boston, Massachusetts, USA
    J Thorac Oncol 6:1841-8. 2011
    ..Identifying participant and program characteristics that influence the cost-effectiveness of screening will help translate trial results into benefits at the population level...
  35. ncbi request reprint Breast cancer prevention: patient decision making and risk communication in the high risk setting
    Elissa M Ozanne
    Institute for Technology Assessment, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Breast J 16:38-47. 2010
    ....
  36. pmc Carboplatin and paclitaxel with vs without bevacizumab in older patients with advanced non-small cell lung cancer
    Junya Zhu
    Center for Patient Safety, Dana Farber Cancer Institute, 450 Brookline Ave, Boston, MA 02215, USA
    JAMA 307:1593-601. 2012
    ..However, longer survival was not observed in the subgroup of patients aged 65 years or older...
  37. pmc Measuring disease-free survival and cancer relapse using Medicare claims from CALGB breast cancer trial participants (companion to 9344)
    Elizabeth B Lamont
    Massachusetts General Hospital Cancer Center and Institute for Technology Assessment, Massachusetts General Hospital, Boston, MA, USA
    J Natl Cancer Inst 98:1335-8. 2006
    ....
  38. ncbi request reprint Radiation therapy after mastectomy between 1991 and 1999 in elderly women: response to clinical trial information
    Rinaa S Punglia
    Department of Radiation Oncology and Center for Outcomes and Policy Research, Division of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 24:3474-82. 2006
    ..We sought to study the receipt of PMRT in elderly women in this period, using a population-based cohort of women with breast cancer...
  39. ncbi request reprint Hope and prognostic disclosure
    Jennifer W Mack
    Center for Outcomes and Policy Research, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    J Clin Oncol 25:5636-42. 2007
    ..Physicians sometimes selectively convey prognostic information to support patients' hopes. However, the relationship between prognostic disclosure and hope is not known...
  40. ncbi request reprint Understanding of prognosis among parents of children with cancer: parental optimism and the parent-physician interaction
    Jennifer W Mack
    Department of Pediatric Oncology, and the Center for Outcomes and Policy Research, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 25:1357-62. 2007
    ..We assessed understanding of likelihood of cure and functional outcome among parents of children with cancer and sought to identify factors that place parents at risk for overly optimistic beliefs about prognosis...
  41. pmc Parents' views of cancer-directed therapy for children with no realistic chance for cure
    Jennifer W Mack
    Center for Outcomes and Policy Research and Department of Pediatric Oncology, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    J Clin Oncol 26:4759-64. 2008
    ..We assessed parents' experiences with treatment for their children with cancer and no realistic chance of cure...
  42. ncbi request reprint Using economic analysis to evaluate the potential of multimodality therapy for elderly patients with locally advanced pancreatic cancer
    Monika K Krzyzanowska
    Department of Adult Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 67:211-8. 2007
    ..Economic modeling can be used to explore the potential of such novel therapies and to inform clinical trial design...
  43. ncbi request reprint Treatment of early stage breast cancer: do surgeons and patients agree regarding whether treatment alternatives were discussed?
    Nancy L Keating
    Division of General Internal Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Breast Cancer Res Treat 79:225-31. 2003
    ..Informing patients of available treatment alternatives is an important element of informed consent. We examined and compared patients' and their surgeons' reports of discussing treatment alternatives for early stage breast cancer...
  44. pmc Relationship between reproductive history, anthropometrics, lifestyle factors, and the likelihood of persistent chemotherapy-related amenorrhea in women with premenopausal breast cancer
    Mary E Abusief
    Department of Obstetrics, Gynecology and Reproductive Biology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Fertil Steril 97:154-9. 2012
    ....
  45. doi request reprint Parents' roles in decision making for children with cancer in the first year of cancer treatment
    Jennifer W Mack
    Center for Outcomes and Policy Research, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    J Clin Oncol 29:2085-90. 2011
    ..To evaluate the extent to which parents of children with cancer are involved in decision making in the ways they prefer during the first year of treatment...
  46. pmc Discussions with physicians about hospice among patients with metastatic lung cancer
    Haiden A Huskamp
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, MA 02115, USA
    Arch Intern Med 169:954-62. 2009
    ..Many terminally ill patients enroll in hospice only in the final days before death or not at all. Discussing hospice with a health care provider could increase awareness of hospice and possibly result in earlier use...
  47. pmc Associations between palliative chemotherapy and adult cancer patients' end of life care and place of death: prospective cohort study
    Alexi A Wright
    Harvard Medical School, Department of Medical Oncology, Dana Farber Cancer Institute, Dana 1133, 450 Brookline Avenue, Boston, MA 02215, USA
    BMJ 348:g1219. 2014
    ..To determine whether the receipt of chemotherapy among terminally ill cancer patients months before death was associated with patients' subsequent intensive medical care and place of death...
  48. pmc Do variations in provider discussions explain socioeconomic disparities in postmastectomy breast reconstruction?
    Caprice C Greenberg
    Center for Surgery and Public Health, Division of Surgical Oncology, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Am Coll Surg 206:605-15. 2008
    ..We investigated whether these differences reflect variations in the rate or qualitative aspects of the provider's discussion of reconstruction as an option...
  49. pmc Palliative radiation therapy practice in patients with metastatic non-small-cell lung cancer: a Cancer Care Outcomes Research and Surveillance Consortium (CanCORS) Study
    Aileen B Chen
    Dana Farber Cancer Institute, 450 Brookline Ave, D1111, Boston, MA 02215, USA
    J Clin Oncol 31:558-64. 2013
    ..We investigated population-based patterns in the use of palliative RT among patients with metastatic non-small-cell lung cancer (NSCLC)...
  50. pmc Pathologic characteristics of second breast cancers after breast conservation for ductal carcinoma in situ
    Nils D Arvold
    Harvard Radiation Oncology Program, Harvard Medical School, Boston, Massachusetts, USA
    Cancer 118:6022-30. 2012
    ..The authors described the characteristics of SBC and examined associations between the pathologic features of SBC and index DCIS cases...
  51. pmc Clinicopathologic features, patterns of recurrence, and survival among women with triple-negative breast cancer in the National Comprehensive Cancer Network
    Nancy U Lin
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USA
    Cancer 118:5463-72. 2012
    ..The objective of this study was to describe clinicopathologic features, patterns of recurrence, and survival according to breast cancer subtype with a focus on triple-negative tumors...
  52. pmc Incidence of severe pain in newly diagnosed ambulatory patients with stage IV cancer
    Thomas Isaac
    Dana Farber Cancer Institute, Boston, MA, USA
    Pain Res Manag 17:347-52. 2012
    ..Pain is common among cancer patients...
  53. ncbi request reprint Estimating long-term effectiveness of lung cancer screening in the Mayo CT screening study
    Pamela M McMahon
    Institute for Technology Assessment, Massachusetts General Hospital, 101 Merrimac St, 10th Floor, Boston, MA 02114, USA
    Radiology 248:278-87. 2008
    ....
  54. pmc Continued use of trastuzumab beyond disease progression in the national comprehensive cancer network: should we practice ahead of the evidence?
    Yu Ning Wong
    Department of Medical Oncology, Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, Pennsylvania 19111 2497, USA
    Oncologist 16:559-65. 2011
    ..Controlled clinical trials that establish a benefit from continued trastuzumab have been difficult to complete...
  55. ncbi request reprint Effect of distance to radiation treatment facility on use of radiation therapy after mastectomy in elderly women
    Rinaa S Punglia
    Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 66:56-63. 2006
    ..We sought to study the effect of distance to the nearest radiation treatment facility on the use of postmastectomy radiation therapy (PMRT) in elderly women...
  56. ncbi request reprint Impact of oncology-related direct-to-consumer advertising: association with appropriate and inappropriate prescriptions
    Gregory A Abel
    Division of Population Sciences, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02215, USA
    Cancer 119:1065-72. 2013
    ....
  57. pmc End-of-life discussions, goal attainment, and distress at the end of life: predictors and outcomes of receipt of care consistent with preferences
    Jennifer W Mack
    Dana Farber Cancer Institute, Department of Pediatric Oncology, 44 Binney St 454, Boston, MA 02115, USA
    J Clin Oncol 28:1203-8. 2010
    ..Physicians have an ethical obligation to honor patients' values for care, including at the end of life (EOL). We sought to evaluate factors that help patients to receive care consistent with their preferences...
  58. pmc Receipt of appropriate surgical care for Medicare beneficiaries with cancer
    Caprice C Greenberg
    Center for Surgery and Public Health, Department of Surgery, Brigham and Women s Hospital, Boston, MA 02115, USA
    Arch Surg 146:1128-34. 2011
    ..To investigate receipt of appropriate surgical care in Medicare beneficiaries with cancer...
  59. ncbi request reprint Parent and physician perspectives on quality of care at the end of life in children with cancer
    Jennifer W Mack
    Department of Pediatric Oncology, Center for Outcomes and Policy Research, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 23:9155-61. 2005
    ..To ascertain parents' and physicians' assessments of quality of end-of-life care for children with cancer and to determine factors associated with high-quality care as perceived by parents and physicians...
  60. pmc Radiation therapy for ductal carcinoma in situ: a decision analysis
    Rinaa S Punglia
    Department of Radiation Oncology, Dana Farber Cancer Institute Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 118:603-11. 2012
    ..The benefit of adding radiation therapy after excision of ductal carcinoma in situ (DCIS) is widely debated. Randomized clinical trials are underpowered to delineate long-term outcomes after radiation...
  61. doi request reprint Reliability of staging, prognosis, and comorbidity data collection in the National Comprehensive Cancer Network (NCCN) non-Hodgkin lymphoma (NHL) multicenter outcomes database
    Michelle E Kho
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Cancer 113:3209-12. 2008
    ..Clinical trials and outcomes studies often rely on nonphysicians to abstract complex data from medical records, but the reliability of these data are rarely assessed...
  62. pmc Adopting helical CT screening for lung cancer: potential health consequences during a 15-year period
    Pamela M McMahon
    Department of Radiology, Massachusetts General Hospital, Boston, MA, USA
    Cancer 113:3440-9. 2008
    ..This study estimated changes in lung cancer outcomes through 2005, had chest CT screening been introduced in 1990...
  63. doi request reprint Treatment of ductal carcinoma in situ after excision: would a prophylactic paradigm be more appropriate?
    Rinaa S Punglia
    Affiliations of authors Department of Radiation Oncology RSP and Division of Medical Oncology JCW, Dana Farber Cancer Institute, Boston, MA Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA SJS
    J Natl Cancer Inst 105:1527-33. 2013
    ....
  64. ncbi request reprint Estimation of mortality rates for disease simulation models using Bayesian evidence synthesis
    Pamela M McMahon
    Institute for Technology Assessment, Massachusetts General Hospital, Boston, MA 02114, USA
    Med Decis Making 26:497-511. 2006
    ..This approach is suggested when modeling a disease that causes a large proportion of all-cause mortality, particularly when mortality from the disease of interest and other-cause mortality are both affected by the same risk factor...
  65. pmc A qualitative study of oncologists' approaches to end-of-life care
    Vicki A Jackson
    Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA
    J Palliat Med 11:893-906. 2008
    ..To understand how oncologists provide care at the end of life, the emotions they experience in the provision of this care, and how caring for dying patients may impact job satisfaction and burnout...
  66. ncbi request reprint Trends in the aggressiveness of cancer care near the end of life
    Craig C Earle
    MSc, Center for Outcomes and Policy Research, Dana Farber Cancer Center, 44 Binney St, 454 STE 21 24, Boston, MA 02115, USA
    J Clin Oncol 22:315-21. 2004
    ..To characterize the aggressiveness of end-of-life cancer treatment for older adults on Medicare, and its relationship to the availability of healthcare resources...
  67. ncbi request reprint Cancer-related direct-to-consumer advertising: awareness, perceptions, and reported impact among patients undergoing active cancer treatment
    Gregory A Abel
    Center for Outcomes and Policy Research, Department of Medical Oncology, Dana Farber Cancer Institute, 44 Binney St, Smith 271, Boston, MA 02115, USA
    J Clin Oncol 27:4182-7. 2009
    ..Although cancer-related direct-to-consumer advertising (CR-DTCA) is prevalent, little is known about cancer patients' experiences with this controversial medium of medical communication...
  68. ncbi request reprint Quality of health care for children: role of health and chronic illness in inpatient care experiences
    Jennifer W Mack
    Dana Farber Cancer Institute, Boston, MA 02115, USA
    Arch Pediatr Adolesc Med 161:828-34. 2007
    ..To assess how parent reports about the inpatient care of their children vary according to the health status of children with and without chronic conditions...
  69. ncbi request reprint Criterion validity of Medicare chemotherapy claims in Cancer and Leukemia Group B breast and lung cancer trial participants
    Elizabeth B Lamont
    Department of Medicine and Institute for Technology Assessment, Massachusetts General Hospital, Boston, MA 02114, USA
    J Natl Cancer Inst 97:1080-3. 2005
    ..Administrative Medicare claims data appear to be a valid source of information for chemotherapy administered to elderly Medicare beneficiaries with cancer...
  70. pmc Satisfaction of the uncertainty principle in cancer clinical trials: retrospective cohort analysis
    Steven Joffe
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    BMJ 328:1463. 2004
    ..This principle is violated if trials systematically favour either the experimental or the standard treatment...
  71. ncbi request reprint The effect of age, race and gender on preference scores for hypothetical health states
    Eve Wittenberg
    Institute for Technology Assessment, Massachusetts General Hospital, 101 Merrimac Street, 10th Floor, Boston, 02114, USA
    Qual Life Res 15:645-53. 2006
    ..This research explored the systematic contribution of respondents' age, race and gender to variability in community perspective preferences for hypothetical health states...
  72. pmc Comparison of referring and final pathology for patients with non-Hodgkin's lymphoma in the National Comprehensive Cancer Network
    Ann S LaCasce
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 26:5107-12. 2008
    ..We sought to estimate the impact of expert review in the modern era by comparing final pathologic diagnoses at five comprehensive cancer centers with diagnoses assigned at referring centers...
  73. pmc Selecting high priority quality measures for breast cancer quality improvement
    Michael J Hassett
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Med Care 46:762-70. 2008
    ..We sought to develop a simple, explicit strategy for prioritizing breast cancer quality measures based on their potential to highlight areas where quality improvement efforts could most impact a population...
  74. ncbi request reprint Assessing the quality of pain care in ambulatory patients with advanced stage cancer
    Saul N Weingart
    Center for Patient Safety, Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA
    J Pain Symptom Manage 43:1072-81. 2012
    ..Pain is common among patients with advanced cancer despite the dissemination of clinical pain care guidelines...
  75. pmc Adoption of gene expression profile testing and association with use of chemotherapy among women with breast cancer
    Michael J Hassett
    Center for Outcomes and Policy Research, Department of Medical Oncology, Dana Farber Cancer Institute, 450 Brookline Ave, Boston, MA 02215, USA
    J Clin Oncol 30:2218-26. 2012
    ..One of the first commercially available GEP tests, a 21-gene profile, was developed to estimate the benefit of adjuvant chemotherapy for hormone receptor-positive breast cancer (HR-positive BC)...
  76. pmc Impact of interval from breast conserving surgery to radiotherapy on local recurrence in older women with breast cancer: retrospective cohort analysis
    Rinaa S Punglia
    Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    BMJ 340:c845. 2010
    ..To determine if the length of interval between breast conserving surgery and start of radiotherapy affects local recurrence and to identify factors that might be associated with delay in older women with breast cancer...
  77. ncbi request reprint Treatment of locally advanced pancreatic cancer in the real world: population-based practices and effectiveness
    Monika K Krzyzanowska
    Center for Outcomes and Policy Research, Dana Farber Cancer Institute, 44 Binney St, 454 STE 21 24, Boston, MA 02115, USA
    J Clin Oncol 21:3409-14. 2003
    ..To evaluate the use and effectiveness of cancer-directed therapy in elderly patients with locally advanced pancreatic cancer (LAPC)...
  78. doi request reprint Unmeasured costs of a child's death: perceived financial burden, work disruptions, and economic coping strategies used by American and Australian families who lost children to cancer
    Veronica Dussel
    Department of Psychosocial Oncology and Palliative Care, Dana Farber Cancer Institute, 44 Binney St SM 206, Boston, MA 02115, USA
    J Clin Oncol 29:1007-13. 2011
    ..We describe the financial hardship, work disruptions, income loss, and coping strategies of families who lost children to cancer...
  79. ncbi request reprint Communication about prognosis between parents and physicians of children with cancer: parent preferences and the impact of prognostic information
    Jennifer W Mack
    Departments of Pediatric Oncology, Center for Outcomes and Policy Research, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 24:5265-70. 2006
    ..We aimed to determine parent preferences for prognostic information about their children with cancer and the results of receiving such information...
  80. ncbi request reprint Optimizing adjuvant endocrine therapy in postmenopausal women with early-stage breast cancer: a decision analysis
    Rinaa S Punglia
    Division of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 23:5178-87. 2005
    ..Options include the antiestrogen tamoxifen, estrogen deprivation with aromatase inhibitors, and sequential therapy with tamoxifen and then an aromatase inhibitor...
  81. ncbi request reprint Comparison of outcomes in cancer patients treated within and outside clinical trials: conceptual framework and structured review
    Jeffrey M Peppercorn
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Lancet 363:263-70. 2004
    ..Many oncologists believe that patients with cancer who enroll in clinical trials have better outcomes than those who do not enroll. We aimed to assess the empirical evidence that such a trial effect exists...
  82. ncbi request reprint Impact of hospital procedure volume on surgical operation and long-term outcomes in high-risk curatively resected rectal cancer: findings from the Intergroup 0114 Study
    Jeffrey A Meyerhardt
    Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    J Clin Oncol 22:166-74. 2004
    ..However, because these studies often lack detailed information on tumor and treatment characteristics as well as cancer recurrence, the true nature of this relation remains uncertain...
  83. pmc A multi-institutional analysis of the socioeconomic determinants of breast reconstruction: a study of the National Comprehensive Cancer Network
    Caprice K Christian
    Department of Surgery, Brigham and Women s Hospital, Boston, MA 02115, and Department of Breast Medical Oncology, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Ann Surg 243:241-9. 2006
    ..To determine the rate of postmastectomy reconstruction and investigate the impact of socioeconomic status on the receipt of reconstruction...
  84. doi request reprint Easing of suffering in children with cancer at the end of life: is care changing?
    Joanne Wolfe
    Department of Pediatric Oncology, Dana Farber Cancer Institute, 44 Binney St, SM 205, Boston, MA 02115, USA
    J Clin Oncol 26:1717-23. 2008
    ..We sought to determine whether national and local efforts have led to changes in patterns of care, advanced care planning, and symptom control among children with cancer at the end of life...
  85. doi request reprint The effects of paclitaxel, dose density, and trastuzumab on treatment-related amenorrhea in premenopausal women with breast cancer
    Mary E Abusief
    Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 116:791-8. 2010
    ..Little information is available regarding the effects of new adjuvant treatment regimens on menstrual functioning in premenopausal women with early breast cancer...
  86. ncbi request reprint Views of American oncologists about the purposes of clinical trials
    Steven Joffe
    Department of Pediatric Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Natl Cancer Inst 94:1847-53. 2002
    ..Many research subjects believe incorrectly that the primary purpose of clinical trials is to benefit the participants rather than to improve therapy for future patients. However, few data are available about how physicians view trials...
  87. ncbi request reprint Identifying potential indicators of the quality of end-of-life cancer care from administrative data
    Craig C Earle
    Division of Population Sciences Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 21:1133-8. 2003
    ..To explore potential indicators of the quality of end-of-life services for cancer patients that could be monitored using existing administrative data...
  88. ncbi request reprint Quality of non-breast cancer health maintenance among elderly breast cancer survivors
    Craig C Earle
    Center for Outcomes and Policy Research, Dana Farber Cancer Center, 44 Binney St, Boston 02115, USA
    J Clin Oncol 21:1447-51. 2003
    ..To assess the quality of preventive health care, the role of health care participation, and the patient and provider characteristics associated with high-quality care for breast cancer survivors...
  89. ncbi request reprint Optimistic expectations and survival after hematopoietic stem cell transplantation
    Stephanie J Lee
    Department of Medical Oncology, and Center for Outcomes and Policy Research, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA
    Biol Blood Marrow Transplant 9:389-96. 2003
    ..Our data suggest an association between more optimistic expectations and early survival following hematopoietic stem cell transplantation, but this association is not present by 6 months posttransplantation...
  90. ncbi request reprint Peer-delivered smoking counseling for childhood cancer survivors increases rate of cessation: the partnership for health study
    Karen M Emmons
    Harvard School of Public Health and Dana Farber Cancer Institute, Center for Community Based Research, Boston, MA 02115, USA
    J Clin Oncol 23:6516-23. 2005
    ..This article reports on the final outcomes of Partnership for Health, a smoking cessation intervention for smokers in the Childhood Cancer Survivors Study (CCSS)...
  91. ncbi request reprint When does quality-adjusting life-years matter in cost-effectiveness analysis?
    Richard H Chapman
    Program on the Economic Evaluation of Medical Technology, Harvard Center for Risk Analysis, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Health Econ 13:429-36. 2004
    ....
  92. ncbi request reprint Impact of referral patterns on the use of chemotherapy for lung cancer
    Craig C Earle
    Center for Outcomes and Policy Research, Dana Farber Cancer Center, Boston, MA 02115, USA
    J Clin Oncol 20:1786-92. 2002
    ..To determine the extent to which unexplained variation in the use of chemotherapy for advanced lung cancer is due to access to oncologists' services as opposed to treatment decisions made after seeing an oncologist...
  93. ncbi request reprint Treatment decision making in early-stage breast cancer: should surgeons match patients' desired level of involvement?
    Nancy L Keating
    Division of General Internal Medicine, Section on Health Services and Policy Research, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    J Clin Oncol 20:1473-9. 2002
    ....
  94. ncbi request reprint Site of oncologic specialty care for older adolescents in Utah
    Karen H Albritton
    Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 25:4616-21. 2007
    ..We used a population-based registry to determine the site of care of children, adolescents, and young adults (age 0 to 24 years) with newly diagnosed cancer...
  95. pmc Disparities in oncologic surgery
    Caprice C Greenberg
    Center for Surgery and Public Health, Brigham and Women s Hospital, 75 Francis Street, Boston, Massachusetts 02115, USA
    World J Surg 32:522-8. 2008
    ..Finally, we attempt to illustrate how all of these factors interact and offer some potential strategies to close the gap and alleviate disparities within the discipline...
  96. ncbi request reprint Patient utilities for advanced cancer: effect of current health on values
    Eve Wittenberg
    MGH Institute for Technology Assessment, Massachusetts General Hospital, and Harvard Medical School, Boston, Massachusetts 02114, USA
    Med Care 43:173-81. 2005
    ..Prospect theory predicts that current health affects values, and that losses loom larger than gains. If true, the use of utilities requires that additional complexities be considered...
  97. ncbi request reprint A population-based study of Ashkenazi Jewish women's attitudes toward genetic discrimination and BRCA1/2 testing
    Lisa Soleymani Lehmann
    Massachusetts General Hospital, General Medicine Division, currently at Brigham and Women s Hospital, Division of General Medicine and Harvard Medical School, Division of Medical Ethics, Boston, Massachusetts 02115, USA
    Genet Med 4:346-52. 2002
    ..In particular, we assessed concerns about group discrimination, perceptions of the advantages and disadvantages of testing, and the relationship between concerns about discrimination and the potential benefits of genetic testing...
  98. ncbi request reprint Direct-to-consumer advertising in oncology: a content analysis of print media
    Gregory A Abel
    Center for Outcomes and Policy Research, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 25:1267-71. 2007
    ..Content analysis of cancer-related direct-to-consumer advertising (DTCA), with a focus on how benefit and risk/adverse effect information is presented, is essential to understanding its potential impact on oncology outcomes...
  99. ncbi request reprint Communication between physicians and older women with localized breast cancer: implications for treatment and patient satisfaction
    Wenchi Liang
    Department of Oncology, Georgetown University Medical Center, Washington, DC 20007, USA
    J Clin Oncol 20:1008-16. 2002
    ....
  100. ncbi request reprint The use of radiation as a component of breast conservation therapy in National Comprehensive Cancer Network Centers
    Thomas A Buchholz
    Department of Radiation Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Clin Oncol 24:361-9. 2006
    ..We investigated rates of radiation use after breast conservation therapy (BCT) for patients treated for ductal carcinoma-in-situ (DCIS) or invasive breast cancer at National Comprehensive Cancer Network (NCCN) centers...
  101. ncbi request reprint Surgical mortality in patients with esophageal cancer: development and validation of a simple risk score
    Ewout W Steyerberg
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    J Clin Oncol 24:4277-84. 2006
    ..We aimed to develop and validate a simple risk score for surgical mortality that could be applied to administrative data...

Research Grants3

  1. Lung/Colon Cancer Outcomes--Cancer Research Network
    Jane Weeks; Fiscal Year: 2005
    ..abstract_text> ..
  2. Lung/Colon Cancer Outcomes--Cancer Research Network
    Jane Weeks; Fiscal Year: 2007
    ..abstract_text> ..
  3. Lung/Colon Cancer Outcomes--Cancer Research Network
    Jane Weeks; Fiscal Year: 2008
    ..abstract_text> ..