Zhaoxi Wang

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Acute health impacts of airborne particles estimated from satellite remote sensing
    Zhaoxi Wang
    Harvard School of Public Health, Massachusetts General Hospital Harvard Medical School, Boston, MA 02115, USA
    Environ Int 51:150-9. 2013
  2. pmc A genome-wide expression analysis in blood identifies pre-elafin as a biomarker in ARDS
    Zhaoxi Wang
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Am J Respir Cell Mol Biol 38:724-32. 2008
  3. pmc Prospective study of metal fume-induced responses of global gene expression profiling in whole blood
    Zhaoxi Wang
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
    Inhal Toxicol 20:1233-44. 2008
  4. pmc Plasma neutrophil elastase and elafin imbalance is associated with acute respiratory distress syndrome (ARDS) development
    Zhaoxi Wang
    Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA
    PLoS ONE 4:e4380. 2009
  5. pmc Genetic polymorphisms of peptidase inhibitor 3 (elafin) are associated with acute respiratory distress syndrome
    Paula Tejera
    Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Room I 1407, Boston, MA 02115, USA
    Am J Respir Cell Mol Biol 41:696-704. 2009
  6. pmc Interactions between environmental factors and polymorphisms in angiogenesis pathway genes in esophageal adenocarcinoma risk: a case-only study
    Rihong Zhai
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Cancer 118:804-11. 2012
  7. pmc Genetic associations with sporadic neuroendocrine tumor risk
    Monica Ter-Minassian
    Environmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Carcinogenesis 32:1216-22. 2011
  8. pmc Global gene expression profiling in whole-blood samples from individuals exposed to metal fumes
    Zhaoxi Wang
    Department of Environmental Health, Occupational Health Program, Harvard School of Public Health, Boston, Massachusetts, USA
    Environ Health Perspect 113:233-41. 2005
  9. pmc Heme oxygenase-1 microsatellite polymorphism and haplotypes are associated with the development of acute respiratory distress syndrome
    Chau Chyun Sheu
    Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Intensive Care Med 35:1343-51. 2009
  10. pmc Genome-wide analysis of survival in early-stage non-small-cell lung cancer
    Yen Tsung Huang
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Clin Oncol 27:2660-7. 2009

Collaborators

Detail Information

Publications17

  1. pmc Acute health impacts of airborne particles estimated from satellite remote sensing
    Zhaoxi Wang
    Harvard School of Public Health, Massachusetts General Hospital Harvard Medical School, Boston, MA 02115, USA
    Environ Int 51:150-9. 2013
    ....
  2. pmc A genome-wide expression analysis in blood identifies pre-elafin as a biomarker in ARDS
    Zhaoxi Wang
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Am J Respir Cell Mol Biol 38:724-32. 2008
    ..52, P = 0.0006). Considering that PI3 can covalently binding to extracellular matrix in lung, circulating PI3 may provide a useful clinical marker for monitoring the early development of ARDS and may have implications for ARDS treatment...
  3. pmc Prospective study of metal fume-induced responses of global gene expression profiling in whole blood
    Zhaoxi Wang
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA
    Inhal Toxicol 20:1233-44. 2008
    ..Furthermore, the acute particulate-induced effects on gene expression profiling were transient in nonsmoking welders, with most effects diminishing within 19 h following exposure...
  4. pmc Plasma neutrophil elastase and elafin imbalance is associated with acute respiratory distress syndrome (ARDS) development
    Zhaoxi Wang
    Department of Environmental Health, Harvard School of Public Health, Boston, MA, USA
    PLoS ONE 4:e4380. 2009
    ..In this study, we tested the hypothesis that an imbalance between neutrophil elastase (HNE) and its inhibitors in blood is related to the development of ARDS...
  5. pmc Genetic polymorphisms of peptidase inhibitor 3 (elafin) are associated with acute respiratory distress syndrome
    Paula Tejera
    Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Room I 1407, Boston, MA 02115, USA
    Am J Respir Cell Mol Biol 41:696-704. 2009
    ..019) at ARDS onset as compared with those homozygous or heterozygous for the variant C allele. Our data suggest that polymorphisms in PI3 gene are significantly associated with ARDS risk and with circulating PI3 levels...
  6. pmc Interactions between environmental factors and polymorphisms in angiogenesis pathway genes in esophageal adenocarcinoma risk: a case-only study
    Rihong Zhai
    Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Cancer 118:804-11. 2012
    ..However, how angiogenic gene polymorphisms and environmental factors jointly affect esophageal adenocarcinoma development remains unclear...
  7. pmc Genetic associations with sporadic neuroendocrine tumor risk
    Monica Ter-Minassian
    Environmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Carcinogenesis 32:1216-22. 2011
    ..Our findings support further investigation of the potential role of IL12A and DAD1 in the etiology of NET...
  8. pmc Global gene expression profiling in whole-blood samples from individuals exposed to metal fumes
    Zhaoxi Wang
    Department of Environmental Health, Occupational Health Program, Harvard School of Public Health, Boston, Massachusetts, USA
    Environ Health Perspect 113:233-41. 2005
    ..This technique can be applied to evaluate the host response to other forms of environmental exposures...
  9. pmc Heme oxygenase-1 microsatellite polymorphism and haplotypes are associated with the development of acute respiratory distress syndrome
    Chau Chyun Sheu
    Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Intensive Care Med 35:1343-51. 2009
    ..The polymorphic (GT)n repeat in the HO-1 gene (HMOX1) promoter regulates HMOX1 expression. We investigated the associations of HMOX1 polymorphisms with acute respiratory distress syndrome (ARDS) risk and plasma HO-1 levels...
  10. pmc Genome-wide analysis of survival in early-stage non-small-cell lung cancer
    Yen Tsung Huang
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Clin Oncol 27:2660-7. 2009
    ..We used genome-wide analysis of tumor tissue to investigate whether single nucleotide polymorphisms (SNPs) in tumors are prognostic factors in early-stage NSCLC...
  11. pmc Distinct and replicable genetic risk factors for acute respiratory distress syndrome of pulmonary or extrapulmonary origin
    Paula Tejera
    Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    J Med Genet 49:671-80. 2012
    ..The aim of this study was to identify genetic variants contributing to ALI/ARDS from pulmonary or extrapulmonary causes...
  12. pmc Correction for population stratification in random forest analysis
    Yang Zhao
    Environmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard School of Public Health, Harvard University, Boston, MA, USA
    Int J Epidemiol 41:1798-806. 2012
    ..However, if PS is not appropriately corrected, RF tends to give high importance to disease-unrelated SNPs with different frequencies of allele or genotype among subpopulations, leading to inaccurate results...
  13. pmc A Large-scale genetic association study of esophageal adenocarcinoma risk
    Chen Yu Liu
    Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    Carcinogenesis 31:1259-63. 2010
    ....
  14. pmc Sparse linear discriminant analysis for simultaneous testing for the significance of a gene set/pathway and gene selection
    Michael C Wu
    Department of Biostatistics, Harvard School of Public Health, 655 Huntington Ave, Boston, MA 02115, USA
    Bioinformatics 25:1145-51. 2009
    ..For a significantly differentially expressed pathway, it is also of substantial interest to select important genes that drive the differential expression of the pathway...
  15. pmc Global metabolomic profiling reveals an association of metal fume exposure and plasma unsaturated fatty acids
    Yongyue Wei
    Department of Environmental Health, Harvard School of Public Health, Harvard University, Boston, Massachusetts, United States of America Department of Epidemiology and Biostatistics, Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, Jiangsu, China
    PLoS ONE 8:e77413. 2013
    ..Few studies have systematically investigated the systemic toxic effects of welding fumes on humans...
  16. ncbi request reprint Gene-smoking interaction associations for the ERCC1 polymorphisms in the risk of lung cancer
    Wei Zhou
    Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:491-6. 2005
    ..In conclusion, ERCC1 8092C > A polymorphism may modify the associations between cumulative cigarette smoking and lung cancer risk...
  17. doi request reprint Circulating mitochondrial DNA in patients in the ICU as a marker of mortality: derivation and validation
    Kiichi Nakahira
    Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America
    PLoS Med 10:e1001577. 2013
    ..We hypothesized that circulating cell-free mtDNA levels would be associated with mortality and improve risk prediction in ICU patients...