Hao Wang

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Telomere length and risk of Parkinson's disease
    Hao Wang
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Mov Disord 23:302-5. 2008
  2. pmc Premorbid body mass index and risk of amyotrophic lateral sclerosis
    Eilis J O'Reilly
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Amyotroph Lateral Scler Frontotemporal Degener 14:205-11. 2013
  3. pmc Restless legs syndrome and Parkinson's disease in men
    Xiang Gao
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
    Mov Disord 25:2654-7. 2010
  4. pmc Vitamin E intake and risk of amyotrophic lateral sclerosis: a pooled analysis of data from 5 prospective cohort studies
    Hao Wang
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Am J Epidemiol 173:595-602. 2011
  5. pmc Restless legs syndrome and erectile dysfunction
    Xiang Gao
    Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Sleep 33:75-9. 2010
  6. ncbi request reprint Early bone apposition in vivo on plasma-sprayed and electrochemically deposited hydroxyapatite coatings on titanium alloy
    Hao Wang
    Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, and Tissue Engineering, VA Boston Healthcare System, MA 02139, USA
    Biomaterials 27:4192-203. 2006
  7. pmc Obesity and restless legs syndrome in men and women
    Xiang Gao
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
    Neurology 72:1255-61. 2009
  8. pmc Smoking and risk of amyotrophic lateral sclerosis: a pooled analysis of 5 prospective cohorts
    Hao Wang
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Arch Neurol 68:207-13. 2011
  9. pmc Notch3 in human breast cancer cell lines regulates osteoblast-cancer cell interactions and osteolytic bone metastasis
    Zhiyuan Zhang
    Department Orthopaedic Surgery, Children s Hospital Boston, Boston, MA 02115, USA
    Am J Pathol 177:1459-69. 2010
  10. doi request reprint Enhanced left atrial reservoir, increased conduit, and weakened booster pump function in hypertensive patients with paroxysmal atrial fibrillation
    Qiqiong Cui
    Department of Echocardiography, FuWai Cardiovascular Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences, Beijing, PR China
    Hypertens Res 31:395-400. 2008

Collaborators

Detail Information

Publications22

  1. pmc Telomere length and risk of Parkinson's disease
    Hao Wang
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Mov Disord 23:302-5. 2008
    ..the highest quartile 0.33; 95% confidence interval: 0.12-0.90). Our results suggest that, contrary to telomere attrition observed in several aging-related diseases, shorter telomeres are not associated with an increased risk of PD...
  2. pmc Premorbid body mass index and risk of amyotrophic lateral sclerosis
    Eilis J O'Reilly
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
    Amyotroph Lateral Scler Frontotemporal Degener 14:205-11. 2013
    ..In conclusion, these findings support an association between lower premorbid BMI and ALS...
  3. pmc Restless legs syndrome and Parkinson's disease in men
    Xiang Gao
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
    Mov Disord 25:2654-7. 2010
    ..In conclusion, men with RLS are more likely to have concurrent PD. Prospective studies are warranted to clarify the temporal relationship between RLS and PD...
  4. pmc Vitamin E intake and risk of amyotrophic lateral sclerosis: a pooled analysis of data from 5 prospective cohort studies
    Hao Wang
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Am J Epidemiol 173:595-602. 2011
    ..002) but not in men (P-trend=0.71). In this large, pooled prospective study, long-term vitamin E supplement use was associated with lower ALS rates. A possible protective effect of vitamin E deserves further consideration...
  5. pmc Restless legs syndrome and erectile dysfunction
    Xiang Gao
    Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Sleep 33:75-9. 2010
    ..Dopaminergic hypofunction in the central nervous system may contribute to restless legs syndrome (RLS) and erectile dysfunction (ED). We therefore examined whether men with RLS have higher prevalences of ED...
  6. ncbi request reprint Early bone apposition in vivo on plasma-sprayed and electrochemically deposited hydroxyapatite coatings on titanium alloy
    Hao Wang
    Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, and Tissue Engineering, VA Boston Healthcare System, MA 02139, USA
    Biomaterials 27:4192-203. 2006
    ....
  7. pmc Obesity and restless legs syndrome in men and women
    Xiang Gao
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
    Neurology 72:1255-61. 2009
    ..We therefore examined whether individuals who are obese have an increased risk of RLS in two ongoing US cohorts, the Nurses' Health Study II and the Health Professional Follow-up Study...
  8. pmc Smoking and risk of amyotrophic lateral sclerosis: a pooled analysis of 5 prospective cohorts
    Hao Wang
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Arch Neurol 68:207-13. 2011
    ..Cigarette smoking has been proposed as a risk factor for amyotrophic lateral sclerosis (ALS), but epidemiological studies supporting this hypothesis have been small and mostly retrospective...
  9. pmc Notch3 in human breast cancer cell lines regulates osteoblast-cancer cell interactions and osteolytic bone metastasis
    Zhiyuan Zhang
    Department Orthopaedic Surgery, Children s Hospital Boston, Boston, MA 02115, USA
    Am J Pathol 177:1459-69. 2010
    ..Taken together, our results suggest that enhanced Notch3 expression in breast cancer cells, triggered by osteoblasts and their secretion of TGFbeta1 in the bone marrow niche, may stand as a novel mechanism for promoting bone metastasis...
  10. doi request reprint Enhanced left atrial reservoir, increased conduit, and weakened booster pump function in hypertensive patients with paroxysmal atrial fibrillation
    Qiqiong Cui
    Department of Echocardiography, FuWai Cardiovascular Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences, Beijing, PR China
    Hypertens Res 31:395-400. 2008
    ..The enhancement of LA reservoir function may be related to the frequency and total number of PAF episodes, and the increased LA conduit function may be related to the LA total emptying volume and frequency of PAF episodes...
  11. pmc Association of bone morphogenetic protein-2 gene polymorphisms with susceptibility to ossification of the posterior longitudinal ligament of the spine and its severity in Chinese patients
    Hao Wang
    Beijing Tiantan Hospital, Capital Medical University CMU, Beijing, 100050, China
    Eur Spine J 17:956-64. 2008
    ..The "G" allele in the Ser87Ser (A/G) polymorphism promotes the extent of OPLL, whereas the "A" allele in the Ser87Ser (A/G) polymorphism restricts ectopic ossification in the cervical spine at least in Chinese subjects...
  12. ncbi request reprint RNA interference mediated silencing of alpha-synuclein in MN9D cells and its effects on cell viability
    Dong mei Liu
    Beijing Institute for Neuroscience, Capital Medical University, Beijing Center of Neural Regeneration and Repair, Key Laboratory for Neurodegenerative Disease of the Ministry of Education, Beijing 100069, China
    Neurosci Bull 24:96-104. 2008
    ..To silence the expression of alpha-synuclein in MN9D dopaminergic cells using vector mediated RNA interference (RNAi) and examined its effects on cell proliferation and viability...
  13. pmc Lateral packing of mineral crystals in bone collagen fibrils
    Christian Burger
    Department of Chemistry, Stony Brook University, Stony Brook, New York, USA
    Biophys J 95:1985-92. 2008
    ..The two-dimensional analytical scheme also leads to quantitative information about the preferred orientation of mineral stacks and the average height of crystals along the crystallographic c axis...
  14. ncbi request reprint [Component analysis of bone matrix via cell extraction]
    Hao Wang
    Department of Tissue Engineering, China Medical University, Shenyang, Liaoning, P R China 110001
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 17:422-4. 2003
    ..To investigate the preparation of bone acellular extra-cell matrix(AECM) and to analyze its component...
  15. ncbi request reprint Quantitation of osteoblast-like cell mineralization on tissue culture polystyrene and Ti-6Al-4V alloy disks by Tc-99m-MDP labeling and imaging in vitro
    Hao Wang
    Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Bone 36:84-92. 2005
    ..The results warrant implementation of this scintigraphic method for quantitative studies of osteoblast-mediated mineralization in vitro...
  16. ncbi request reprint A search for CDKN2A/p16INK4a mutations in melanocytic nevi from patients with melanoma and spouse controls by use of laser-captured microdissection
    Hao Wang
    Department of Medicine, Division of Dermatology, University of Washington, Seattle 98195, USA
    Arch Dermatol 141:177-80. 2005
    ..To determine the frequency at which the CDKN2A coding region is mutated in the atypical nevi of persons with sporadic melanoma...
  17. ncbi request reprint Placental expression of enzymes regulating prostaglandin synthesis and degradation
    Emmet Hirsch
    Department of Obstetrics and Gynecology, Evanston Northwestern Healthcare, IL, USA
    Am J Obstet Gynecol 192:1836-42; discussion 1842-3. 2005
    ..The purpose of this study was to characterize placental expression of the prostaglandin synthase enzymes cyclooxygenase (COX) -1 and -2 and prostaglandin dehydrogenase (PGDH, a degrading enzyme)...
  18. ncbi request reprint Atopic diseases, immunoglobulin E and risk of cancer of the prostate, breast, lung and colorectum
    Hao Wang
    Department of Clinical Social Medicine, University of Heidelberg, and Unit of Health Monitoring, Saarland Cancer Registry, Saarbrucken, Germany
    Int J Cancer 119:695-701. 2006
    ..The effect on cancer risk by atopy, defined by IgE reactivity, may differ from the effect by atopy-related clinically defined diseases such as asthma, hay fever and atopic dermatitis...
  19. ncbi request reprint Identification and characterization of 4-methylbenzyl 4-[(pyrimidin-2-ylamino)methyl]piperidine-1-carboxylate, an orally bioavailable, brain penetrant NR2B selective N-methyl-D-aspartate receptor antagonist
    Nigel J Liverton
    Department of Medicinal Chemistry, Merck Research Laboratories, West Point, Pennsylvania 19486, USA
    J Med Chem 50:807-19. 2007
    ..Compound 20j demonstrated efficacy in in vivo rodent models of antinociception, allodynia, and Parkinson's disease...
  20. ncbi request reprint Cathepsin D is secreted from M-BE cells: its potential role as a biomarker of lung cancer
    Xiaomin Lou
    Division of Proteomics, Beijing Genomics Institute, Chinese Academy of Sciences, Beijing 101318, P R China
    J Proteome Res 6:1083-92. 2007
    ..001). The present study has revealed that M-BE cells at different passages could secrete or release some proteins into the living environment, which might serve as the potential resource for exploring the biomarkers of lung cancer...
  21. doi request reprint Assessment of atrial electromechanical coupling and influential factors in nonrheumatic paroxysmal atrial fibrillation
    Qi Qiong Cui
    Department of Echocardiography, FuWai Cardiovascular Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences, 167 Beilishi Road, Beijing, China
    Clin Cardiol 31:74-8. 2008
    ..Sequential analysis of atrial electromechanical coupling (P-A) by Doppler tissue imaging (DTI) might provide important insight into the mechanisms of paroxysmal atrial fibrillation (PAF)...
  22. ncbi request reprint Functional and pharmacological properties of canine ERG potassium channels
    Jixin Wang
    Department of Molecular Pharmacology, Merck Research Laboratories, West Point, Pennsylvania 19486, USA
    Am J Physiol Heart Circ Physiol 284:H256-67. 2003
    ..A novel MK-499 binding assay provides a new tool to detect agents affecting ERG channels...