Research Topics
| Matthew P WalkerSummaryAffiliation: Harvard University Country: USA Publications
| Collaborators
|
Detail Information
Publications
Practice with sleep makes perfect: sleep-dependent motor skill learningMatthew P Walker
Laboratory of Neurophysiology, Department of Psychiatry, Harvard Medical School, 74 Fenwood Road, Boston, Massachusetts 02115, USA
Neuron 35:205-11. 2002..This finding of sleep-dependent motor skill improvement may have important implications for the efficient learning of all skilled actions in humans...- It's practice, with sleep, that makes perfect: implications of sleep-dependent learning and plasticity for skill performanceMatthew P Walker
Sleep and Neuroimaging, Center for Sleep and Cognition, Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
Clin Sports Med 24:301-17, ix. 2005..In conclusion, a consideration of the fundamental importance of sleep in real-life skill learning is provided... - A refined model of sleep and the time course of memory formationMatthew P Walker
Sleep and Neuroimaging Laboratory, Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Behav Brain Sci 28:51-64; discussion 64-104. 2005..These include the upregulation of select plasticity-associated genes, increased protein synthesis, changes in neurotransmitter concentration, and specific electrical events in neuronal networks that modulate synaptic potentiation... - Issues surrounding sleep-dependent memory consolidation and plasticityM P Walker
Sleep and Neuroimaging Laboratory, Center for Sleep and Cognition, Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA
Cell Mol Life Sci 61:3009-15. 2004..Here we reflect on these findings, and explore how they maybe reconcilable in a unified approach to understanding the roles of wake, sleep and specific sleep stages in successful memory processing and brain plasticity... - Sleep, memory, and plasticityMatthew P Walker
Sleep and Neuroimaging, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
Annu Rev Psychol 57:139-66. 2006.... - Sleep-dependent learning and memory consolidationMatthew P Walker
Center for Sleep and Cognition, Department of Psychiatry, Harvard Medical School, Beth Israel Deaconess Medical Center E FD 861, 330 Brookline Avenue, Boston, MA 02215, USA
Neuron 44:121-33. 2004..We close (4) with a consideration of unanswered questions as well as existing arguments against the role of sleep in learning and memory and (5) a concluding summary... - Dissociable stages of human memory consolidation and reconsolidationMatthew P Walker
Laboratory of Neurophysiology, Massachusetts Mental Health Center, Department of Psychiatry, Harvard Medical School, 74 Fenwood Road, Boston, Massachusetts 02115, USA
Nature 425:616-20. 2003.... 
Sleep and the time course of motor skill learningMatthew P Walker
Massachusetts Mental Health Center, Department of Psychiatry, Harvard Medical School, Boston, Massachusetts 02115, USA
Learn Mem 10:275-84. 2003..Finally, whereas the majority of sleep-dependent motor-skill learning develops during the first night of sleep following training, additional nights of sleep still offer continued improvements...- Cognitive flexibility across the sleep-wake cycle: REM-sleep enhancement of anagram problem solvingMatthew P Walker
Department of Psychiatry, Harvard Medical School, 74 Fenwood Road, Boston, MA 02115, USA
Brain Res Cogn Brain Res 14:317-24. 2002.... - Sleep-dependent motor memory plasticity in the human brainM P Walker
Sleep and Neuroimaging Laboratory, FD Feldberg 862, Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
Neuroscience 133:911-7. 2005..This evidence of an overnight, systems-level change in the representation of a motor memory holds important implications for acquiring real-life skills and in clinical rehabilitation following brain trauma, such as stroke... - The role of sleep in false memory formationJessica D Payne
Center for Sleep and Cognition, Department of Psychiatry, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Neurobiol Learn Mem 92:327-34. 2009..While these effects produce memories that are less accurate after sleep, these memories may, in the end, be more useful... - A deficit in the ability to form new human memories without sleepSeung Schik Yoo
Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Nat Neurosci 10:385-92. 2007..It therefore appears that sleep before learning is critical in preparing the human brain for next-day memory formation-a worrying finding considering society's increasing erosion of sleep time... - REM sleep depotentiates amygdala activity to previous emotional experiencesEls van der Helm
Sleep and Neuroimaging Laboratory, Department of Psychology, University of California, Berkeley, Berkeley, CA 94720 1650, USA
Curr Biol 21:2029-32. 2011.... - Sleep deprivation amplifies reactivity of brain reward networks, biasing the appraisal of positive emotional experiencesNinad Gujar
Sleep and Neuroimaging Laboratory, Department of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, California 94720 1650, USA
J Neurosci 31:4466-74. 2011..Such findings may offer a neural foundation on which to consider interactions between sleep loss and emotional reactivity in a variety of clinical mood disorders... - Sleep-dependent memory consolidation and reconsolidationRobert Stickgold
Center for Sleep and Cognition, Department of Psychiatry, Harvard Medical School, Beth Israel Deaconess Medical Center E FD 861, 330 Brookline Ave, Boston, MA 02215, USA
Sleep Med 8:331-43. 2007..In this chapter, we review the role of sleep in supporting these disparate but related processes... - The functional anatomy of sleep-dependent visual skill learningMatthew P Walker
Sleep and Neuroimaging Laboratory, Center for Sleep and Cognition, Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
Cereb Cortex 15:1666-75. 2005..Together, these data provide evidence of overnight bi-directional changes in functional anatomy, differences that may form the neural basis of sleep-dependent learning expressed on this task... - Sleep and memory: the ongoing debateRobert Stickgold
Department of Psychiatry, Harvard Medical School and Center for Sleep and Cognition, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Sleep 28:1225-7. 2005..Despite this evidence, debate continues to rage over the very existence of sleep-dependent learning and memory processing. We briefly review here the evidence in support of sleep's role in memory consolidation... - Memory consolidation and reconsolidation: what is the role of sleep?Robert Stickgold
Center for Sleep and Cognition, Department of Psychiatry, Harvard Medical School, Beth Israel Deaconess Medical Center E FD 861, 330 Brookline Avenue, Boston MA 02215, USA
Trends Neurosci 28:408-15. 2005..As such, consolidation and reconsolidation might be better thought of as memory organization and reorganization. A rapidly growing body of evidence suggests that many of these processes are optimally engaged during sleep... - Sleep deprivation impairs the accurate recognition of human emotionsEls van der Helm
Sleep and Neuroimaging Laboratory, Department of Psychology, University of California, Berkeley, CA 94720 1650, USA
Sleep 33:335-42. 2010..Investigate the impact of sleep deprivation on the ability to recognize the intensity of human facial emotions... - Overnight therapy? The role of sleep in emotional brain processingMatthew P Walker
Sleep and Neuroimaging Laboratory, Department of Psychology, University of California, Berkeley, California 94720 1650, USA
Psychol Bull 135:731-48. 2009.... 
The role of sleep in cognition and emotionMatthew P Walker
Sleep and Neuroimaging Laboratory, Department of Psychology and Helen Wills Neuroscience Institute, University of California, Berkeley, California 94720 1650, USA
Ann N Y Acad Sci 1156:168-97. 2009..Finally, and building on this latter topic, a novel hypothesis and framework of sleep-dependent affective brain processing will be proposed, culminating in testable predictions and translational implications for mood disorders...- The influence of sleep on auditory learning: a behavioral studyNadine Gaab
Department of Neurology, Music and Neuroimaging Laboratory, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
Neuroreport 15:731-4. 2004..These data add to the growing literature describing sleep-dependent learning throughout sensory and motor domains... - Sleep facilitates consolidation of emotional declarative memoryPeter Hu
Sleep and Neuroimaging Laboratory, Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
Psychol Sci 17:891-8. 2006..These findings hold important implications for understanding of human memory processing, suggesting that the facilitation of memory for emotionally salient information may preferentially develop during sleep... 
Daytime naps, motor memory consolidation and regionally specific sleep spindlesMasaki Nishida
Sleep and Neuroimaging Laboratory, Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America
PLoS ONE 2:e341. 2007....- The role of sleep in directed forgetting and remembering of human memoriesJared M Saletin
Sleep and Neuroimaging Laboratory, Department of Psychology, University of California, Berkeley, CA 94720 1650, USA
Cereb Cortex 21:2534-41. 2011..Instead, they suggest a model in which sleep may be more ecologically attuned to instructions present during learning while awake, supporting both remembering and targeted forgetting of human memories... - Human relational memory requires time and sleepJeffrey M Ellenbogen
Sleep and Neuroimaging Laboratory, Department of Psychiatry, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 104:7723-8. 2007.... - Sleep-dependent learning and motor-skill complexityKenichi Kuriyama
Center for Sleep and Cognition, Department of Psychiatry, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
Learn Mem 11:705-13. 2004..4% improvement. Together, these findings suggest that the sleep-dependent learning process selectively provides maximum benefit to motor-skill procedures that proved to be most difficult prior to sleep... - Sleep, memory and emotionMatthew P Walker
Sleep and Neuroimaging Laboratory, Department of Psychology, Helen Wills Neuroscience Institute, University of California, Berkeley, CA, USA
Prog Brain Res 185:49-68. 2010..Finally, and building on this latter topic, a novel hypothesis and framework of sleep-dependent affective brain processing will be proposed, culminating in testable predictions and translational implications for mood disorders... - Cognitive consequences of sleep and sleep lossMatthew P Walker
Sleep and Neuroimaging Laboratory, Department of Psychology, University of California, Berkeley, CA 94720 1650, USA
Sleep Med 9:S29-34. 2008..Taken together, these observations are of particular ecologic importance from a professional and education perspective when considering that sleep time continues to decrease across all age ranges throughout industrialized nations... - A role for REM sleep in recalibrating the sensitivity of the human brain to specific emotionsNinad Gujar
Sleep and Neuroimaging Laboratory, Department of Psychology, University of California, Berkeley, CA 94720 1650, USA
Cereb Cortex 21:115-23. 2011..These findings support the view that sleep, and specifically REM neurophysiology, may represent an important factor governing the optimal homeostasis of emotional brain regulation... - Linking brain and behavior in sleep-dependent learning and memory consolidationRobert Stickgold
Department of Psychiatry, Massachusetts Mental Health Center, Harvard Medical School, 74 Fenwood Road, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 99:16519-21. 2002 - Sleep-dependent memory triage: evolving generalization through selective processingRobert Stickgold
Center for Sleep and Cognition, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA
Nat Neurosci 16:139-45. 2013.... - Nocturnal mnemonics: sleep and hippocampal memory processingJared M Saletin
Sleep and Neuroimaging Laboratory, Department of Psychology, University of California Berkeley, CA, USA
Front Neurol 3:59. 2012..Consequently, sleep promotes the targeted strengthening of some memories while actively forgetting others; a proposal with significant theoretical and clinical ramifications... - The human emotional brain without sleep--a prefrontal amygdala disconnectSeung-Schik Yoo
Curr Biol 17:R877-8. 2007