Alina M Vrabioiu
Affiliation: Harvard University
- The majority of the Saccharomyces cerevisiae septin complexes do not exchange guanine nucleotidesAlina M Vrabioiu
Department of Systems Biology, Harvard University, Boston, MA 02115, USA
J Biol Chem 279:3111-8. 2004..We conclude that bound GTP and GDP play a structural, rather then regulatory, role for the majority of septins in proliferating cells as GTP does for alpha-tubulin...
- Structural insights into yeast septin organization from polarized fluorescence microscopyAlina M Vrabioiu
Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, Massachusetts 02115, USA
Nature 443:466-9. 2006..These data resolve a long-standing controversy in the field and provide strong evidence that septins have a mechanical function in cell division...
- Symmetry of septin hourglass and ring structuresAlina M Vrabioiu
Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA
J Mol Biol 372:37-49. 2007..We discuss possible anisotropic processes that could break the septin symmetry and establish the essential bud-neck asymmetry...