Demetrios Vavvas

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint In vivo high-resolution retinal imaging using adaptive optics
    Babak Jian Seyedahmadi
    Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Semin Ophthalmol 25:186-91. 2010
  2. pmc Therapeutic interventions against inflammatory and angiogenic mediators in proliferative diabetic retinopathy
    Daniel Gologorsky
    Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02131, USA
    Mediators Inflamm 2012:629452. 2012
  3. pmc Mechanisms of inflammation in proliferative vitreoretinopathy: from bench to bedside
    Stavros N Moysidis
    Retina Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA
    Mediators Inflamm 2012:815937. 2012
  4. pmc RIP kinase-mediated necrosis as an alternative mechanisms of photoreceptor death
    Yusuke Murakami
    Retina Service, Angiogenesis Laboratory, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Oncotarget 2:497-509. 2011
  5. pmc Intraoperative switch to a temporal surgical approach in 23- and 25-gauge microcannula-based sutureless transconjunctival vitrectomy
    Szilard Kiss
    Retina Service, Weill Cornell Medical College, Department of Ophthalmology, 1305 York Ave, 11th Floor, New York, New York 10021, USA
    Open Ophthalmol J 4:12-4. 2010
  6. ncbi request reprint Mechanisms of disease: cataracts
    Demetrios Vavvas
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA
    Ophthalmol Clin North Am 15:49-60. 2002
  7. doi request reprint Posterior uveal melanoma in young patients treated with proton beam therapy
    Demetrios Vavvas
    Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02131, USA
    Retina 30:1267-71. 2010
  8. doi request reprint In vivo evaluation of laser-induced choroidal neovascularization using spectral-domain optical coherence tomography
    Andrea Giani
    Angiogenesis and Laser Laboratories, Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 52:3880-7. 2011
  9. doi request reprint Anti-vascular endothelial growth factor monotherapy versus combination treatment with photodynamic therapy for subfoveal choroidal neovascularization secondary to causes other than age-related macular degeneration
    Ling Chen
    Retina Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA
    Retina 31:2078-83. 2011
  10. pmc Development of an efficiently cleaved, bioactive, highly pure FLAG-tagged recombinant human Mullerian Inhibiting Substance
    Thanos D Papakostas
    Angiogenesis Laboratory, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 325 Cambridge St, Boston, MA, USA
    Protein Expr Purif 70:32-8. 2010

Collaborators

Detail Information

Publications19

  1. doi request reprint In vivo high-resolution retinal imaging using adaptive optics
    Babak Jian Seyedahmadi
    Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Semin Ophthalmol 25:186-91. 2010
    ..In this review we will be discussing the basic technology of adaptive optics and hardware requirement in addition to clinical applications of such technology...
  2. pmc Therapeutic interventions against inflammatory and angiogenic mediators in proliferative diabetic retinopathy
    Daniel Gologorsky
    Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02131, USA
    Mediators Inflamm 2012:629452. 2012
    ..We focus a detailed discussion on the current targeted therapeutic interventions used to treat diabetic retinopathy...
  3. pmc Mechanisms of inflammation in proliferative vitreoretinopathy: from bench to bedside
    Stavros N Moysidis
    Retina Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, MA 02114, USA
    Mediators Inflamm 2012:815937. 2012
    ..Here we review inflammatory and other mechanisms involved in the pathogenesis of PVR, we highlight important clinical trials, and we discuss how findings at the bench have the potential to be translated to the bedside...
  4. pmc RIP kinase-mediated necrosis as an alternative mechanisms of photoreceptor death
    Yusuke Murakami
    Retina Service, Angiogenesis Laboratory, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Oncotarget 2:497-509. 2011
    ..Here, we summarize the current knowledge of RIP kinase-mediated necrotic signaling and its contribution to photoreceptor death...
  5. pmc Intraoperative switch to a temporal surgical approach in 23- and 25-gauge microcannula-based sutureless transconjunctival vitrectomy
    Szilard Kiss
    Retina Service, Weill Cornell Medical College, Department of Ophthalmology, 1305 York Ave, 11th Floor, New York, New York 10021, USA
    Open Ophthalmol J 4:12-4. 2010
    ....
  6. ncbi request reprint Mechanisms of disease: cataracts
    Demetrios Vavvas
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA
    Ophthalmol Clin North Am 15:49-60. 2002
    ..Thus, all transparency mechanisms and all cataractogenic factors can be thought of as opposing effectors of spatial density fluctuation affecting scatter and antithetical producers of light absorbing moieties...
  7. doi request reprint Posterior uveal melanoma in young patients treated with proton beam therapy
    Demetrios Vavvas
    Retina Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02131, USA
    Retina 30:1267-71. 2010
    ..The purpose was to study the clinical profile and prognosis of young patients with uveal melanoma treated by proton beam irradiation...
  8. doi request reprint In vivo evaluation of laser-induced choroidal neovascularization using spectral-domain optical coherence tomography
    Andrea Giani
    Angiogenesis and Laser Laboratories, Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 52:3880-7. 2011
    ..To describe the in vivo evolution of laser-induced choroidal neovascularization (CNV) in mice using spectral domain optical coherence tomography (SD-OCT)...
  9. doi request reprint Anti-vascular endothelial growth factor monotherapy versus combination treatment with photodynamic therapy for subfoveal choroidal neovascularization secondary to causes other than age-related macular degeneration
    Ling Chen
    Retina Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, USA
    Retina 31:2078-83. 2011
    ..To compare the visual outcomes and retreatment rates of monotherapy with intravitreal bevacizumab versus combination with photodynamic therapy for choroidal neovascularization secondary to causes other than age-related macular degeneration...
  10. pmc Development of an efficiently cleaved, bioactive, highly pure FLAG-tagged recombinant human Mullerian Inhibiting Substance
    Thanos D Papakostas
    Angiogenesis Laboratory, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 325 Cambridge St, Boston, MA, USA
    Protein Expr Purif 70:32-8. 2010
    ..The availability of this fully functional, epitope tagged form of MIS should facilitate scale-up for preclinical and clinical use and should also be used for the study of MIS binding proteins and for tracking in pharmacokinetic studies...
  11. ncbi request reprint Two cases of orbital lymphangioma associated with vascular abnormalities of the retina and iris
    Demetrios Vavvas
    Ophthalmic Plastic, Orbital, Reconstructive, and Cosmetic Surgery Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthalmology 111:189-92. 2004
    ..To report 2 patients with combined intraocular and orbital vascular abnormalities...
  12. doi request reprint Low rate of endophthalmitis in a large series of open globe injuries
    Christopher M Andreoli
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and Harvard Medical School, Boston, Massachusetts, USA
    Am J Ophthalmol 147:601-608.e2. 2009
    ..To determine the percentage of patients in whom endophthalmitis developed after open globe injury...
  13. doi request reprint Review of the ocular angiogenesis animal models
    Sandra R Montezuma
    Retina Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA sandra
    Semin Ophthalmol 24:52-61. 2009
    ..In addition, knockout or knock-in transgenic mice provide powerful tools in studying the role of specific proteins in angiogenesis...
  14. doi request reprint A novel nonradioactive method to evaluate vascular barrier breakdown and leakage
    George Trichonas
    Retina Service, Angiogenesis Laboratory Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Invest Ophthalmol Vis Sci 51:1677-82. 2010
    ..To identify a novel, sensitive, nonradioactive leakage assay that can be used in the assessment of retinal vascular permeability in rats and mice...
  15. pmc Heat shock protein 70 (HSP70) is critical for the photoreceptor stress response after retinal detachment via modulating anti-apoptotic Akt kinase
    Maki Kayama
    Retina Service, Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, and the Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts 02114, USA
    Am J Pathol 178:1080-91. 2011
    ..Thus, HSP70 may be a favorable potential target to increase photoreceptor cell survival after RD...
  16. pmc Utilizing targeted gene therapy with nanoparticles binding alpha v beta 3 for imaging and treating choroidal neovascularization
    Hani Salehi-Had
    Angiogenesis Laboratory, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 6:e18864. 2011
    ..We investigated whether a novel intravenously injectable αvβ3 integrin-ligand coupled nanoparticle (NP) can target choroidal neovascular membranes (CNV) for imaging and targeted gene therapy...
  17. pmc Choroidal neovascular membrane formation and retinochoroidopathy in a patient with systemic langerhans cell histiocytosis: a case report and review of the literature
    Aristomenis Thanos
    Retina Department, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Mass, USA
    Case Report Ophthalmol 3:128-35. 2012
    ..This report aims to raise awareness among ophthalmologists concerning the potential intraocular sequelae of LCH...
  18. ncbi request reprint Pegaptanib (Macugen): treating neovascular age-related macular degeneration and current role in clinical practice
    Demetrios Vavvas
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA
    Ophthalmol Clin North Am 19:353-60. 2006
    ..In addition, these studies widen the armamentarium and open up the possibility of combination therapy in attacking neovascularization through multiple ways...
  19. ncbi request reprint Optical coherence tomography appearance of a retinal artery macroaneurysm
    Aaron Savar
    Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Ophthalmic Surg Lasers Imaging 40:403-4. 2009
    ..The authors present the first report of the high-resolution optical coherence tomography appearance of an unruptured retinal artery macroaneurysm...