Research Topics
| Glenn R ValdezSummaryAffiliation: Harvard University Country: USA Publications
Research Grants
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Detail Information
Publications
Increased anxiety-like behavior and ethanol self-administration in dependent rats: reversal via corticotropin-releasing factor-2 receptor activationGlenn R Valdez
Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California, USA
Alcohol Clin Exp Res 28:865-72. 2004....- Allostasis and dysregulation of corticotropin-releasing factor and neuropeptide Y systems: implications for the development of alcoholismGlenn R Valdez
Department of Neuropharmacology, The Scripps Research Institute, La Jolla, CA 92037, USA
Pharmacol Biochem Behav 79:671-89. 2004.... - Human urocortin 2, a corticotropin-releasing factor (CRF)2 agonist, and ovine CRF, a CRF1 agonist, differentially alter feeding and motor activityEric P Zorrilla
Department of Neuropharmacology, CVN 7, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
J Pharmacol Exp Ther 310:1027-34. 2004..The results suggest the existence of distinct forms of CRF1- and CRF2-mediated anorexia... - Antagonism of corticotropin-releasing factor attenuates the enhanced responsiveness to stress observed during protracted ethanol abstinenceGlenn R Valdez
Department of Neuropharmacology, CVN 7, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA
Alcohol 29:55-60. 2003..Results of the current experiment demonstrated that continuous exposure to ethanol over a 3-week period leads to an increased behavioral responsiveness to stress, which seems to be regulated by CRF... - Measuring meals: structure of prandial food and water intake of ratsEric P Zorrilla
Department of Neuropharmacology, CVN 7, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
Am J Physiol Regul Integr Comp Physiol 288:R1450-67. 2005..Thus log-survivorship analysis is not appropriate for identifying meal breakpoints, and the consideration of drinking in meal definitions can provide a better estimate of meal structure... - Locomotor suppressive and anxiolytic-like effects of urocortin 3, a highly selective type 2 corticotropin-releasing factor agonistGlenn R Valdez
Department of Neuropharmacology, CVN7, Scripps Research Institute, 10550 North Torrey Pines Rd, La Jolla, CA 92037, USA
Brain Res 980:206-12. 2003.... - Reduction of anxiety after restricted feeding in the rat: implication for eating disordersKoki Inoue
Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California, USA
Biol Psychiatry 55:1075-81. 2004..The findings might have etiologic and pathophysiologic relevance for the restrained eating pattern in eating-disorder patients with comorbid anxious symptoms... - Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: regulation by corticotropin-releasing factorGlenn R Valdez
Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California 92037, USA
Alcohol Clin Exp Res 26:1494-501. 2002..The objective of the present study was to investigate the role of CRF in the regulation of ethanol self-administration and to examine the behavioral stress response during acute withdrawal and protracted abstinence... - Leptin and post-prandial satiety: acute central leptin more potently reduces meal frequency than meal size in the ratEric P Zorrilla
Department of Neuropharmacology, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
Psychopharmacology (Berl) 177:324-35. 2005..Many attempts to understand ingestion have sought to clarify the control of meals. Little is known about the effects of the anorexogenic hormone leptin on meal patterning... - Human urocortin II, a selective agonist for the type 2 corticotropin-releasing factor receptor, decreases feeding and drinking in the ratKoki Inoue
Department of Neuropharmacology, The Scripps Research Institute, La Jolla, California, USA
J Pharmacol Exp Ther 305:385-93. 2003..hUcn II is a promising neuropeptide for investigating the role of the CRF(2) receptor in ingestive behavior... - Effects of antalarmin, a CRF type 1 receptor antagonist, on anxiety-like behavior and motor activation in the ratEric P Zorrilla
Department of Neuropharmacology, CVN 7, The Scripps Research Institute, 10550 N Torrey Pines Rd, La Jolla, CA 92037, USA
Brain Res 952:188-99. 2002.... - Intravenous self-administration of etonitazene alone and combined with cocaine in rhesus monkeys: comparison with heroin and antagonism by naltrexone and naloxonazineCindy Achat-Mendes
Division of Neuroscience, New England Primate Research Center, Harvard Medical School, Southborough, MA 01772, USA
Psychopharmacology (Berl) 204:489-98. 2009.... - Human urocortin II: mild locomotor suppressive and delayed anxiolytic-like effects of a novel corticotropin-releasing factor related peptideGlenn R Valdez
Department of Neuropharmacology, CVN7, The Scripps Research Institute, La Jolla, CA 92037, USA
Brain Res 943:142-50. 2002..Thus, hUcn II exhibits mild motor suppressive effects and delayed anxiolytic-like effects, suggesting a time-dependent role for hUcn II in the regulation of stress-related behavior... - Kappa agonist-induced reinstatement of cocaine seeking in squirrel monkeys: a role for opioid and stress-related mechanismsGlenn R Valdez
Division of Behavioral Biology, New England Primate Research Center, Harvard Medical School, Southborough, Massachusetts, USA
J Pharmacol Exp Ther 323:525-33. 2007..The results point to interactions between a subpopulation of kappa opioid receptors and central corticotropin-releasing factor and noradrenergic stress systems in the reinstatement of cocaine seeking induced by kappa agonists... - Stress enhancement of craving during sobriety: a risk for relapseGeorge R Breese
Bowles Center for Alcohol Studies, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
Alcohol Clin Exp Res 29:185-95. 2005..Collectively, the presentations provided convincing support for an involvement of stress in the cause of relapse and continuing alcohol abuse and suggested novel pharmacological approaches for treating relapse induced by stress... - Development of CRF1 receptor antagonists as antidepressants and anxiolytics: progress to dateGlenn R Valdez
Department of Psychology, Grand Valley State University, Allendale, MI 49401, USA
CNS Drugs 20:887-96. 2006..Further development of these compounds is warranted...
Research Grants
- Opioid and Dopamine Mechanisms of Heroin RelapseGLENN VALDEZ; Fiscal Year: 2006....