Naoshige Uchida

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Coding and transformations in the olfactory system
    Naoshige Uchida
    Department of Molecular and Cellular Biology, Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138 email
    Annu Rev Neurosci 37:363-85. 2014
  2. pmc Olfactory cortical neurons read out a relative time code in the olfactory bulb
    Rafi Haddad
    Center for Brain Science, Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, USA
    Nat Neurosci 16:949-57. 2013
  3. pmc The dorsomedial striatum encodes net expected return, critical for energizing performance vigor
    Alice Y Wang
    Center for Brain Science, Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, USA
    Nat Neurosci 16:639-47. 2013
  4. pmc Neuron-type-specific signals for reward and punishment in the ventral tegmental area
    Jeremiah Y Cohen
    Department of Molecular and Cellular Biology, Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138, USA
    Nature 482:85-8. 2012
  5. ncbi request reprint Division of labor for division: inhibitory interneurons with different spatial landscapes in the olfactory system
    Naoshige Uchida
    Center for Brain Science, Department of Molecular and Cellular Biology, 16 Divinity Avenue, Cambridge, MA 02138, USA Electronic address
    Neuron 80:1106-9. 2013
  6. doi request reprint Whole-brain mapping of direct inputs to midbrain dopamine neurons
    Mitsuko Watabe-Uchida
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Neuron 74:858-73. 2012
  7. pmc Odor representations in olfactory cortex: distributed rate coding and decorrelated population activity
    Keiji Miura
    Center for Brain Science, Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Neuron 74:1087-98. 2012
  8. pmc An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger
    Michael J Krashes
    1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA 2 Diabetes, Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA M J K National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland 21224, USA M J K Cardiovascular and Metabolic Diseases, Pfizer, 610 Main Street, Cambridge, Massachusetts 02139, USA B P S Division of Pediatric Endocrinology, Departments of Pediatrics, University of Michigan, Ann Arbor, Michigan 48105, USA D P O Cardiovascular and Metabolic Diseases, Novartis Institutes for BioMedical Research, 100 Technology Square, Cambridge, Massachusetts 02139, USA L V 3
    Nature 507:238-42. 2014
  9. doi request reprint Robust odor coding via inhalation-coupled transient activity in the mammalian olfactory bulb
    Kevin M Cury
    Department of Molecular and Cellular Biology, Harvard University, Center for Brain Science, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Neuron 68:570-85. 2010
  10. pmc Opening the black box: dopamine, predictions, and learning
    Neir Eshel
    Center for Brain Science, Department of Molecular and Cellular Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Trends Cogn Sci 17:430-1. 2013

Collaborators

  • Rafi Haddad
  • Keiji Miura
  • Neir Eshel
  • Zachary F Mainen
  • Mitsuko Watabe-Uchida
  • Michael J Krashes
  • Bradford B Lowell
  • Alice Y Wang
  • Linh Vong
  • Jeremiah Y Cohen
  • Kevin M Cury
  • Alastair S Garfield
  • David P Olson
  • Hongjuan Pei
  • Bhavik P Shah
  • Joseph C Madara
  • Stephen D Liberles
  • David E Strochlic
  • Archana Vamanrao
  • Sebastian Haesler
  • Sachie K Ogawa
  • Lisa Zhu

Detail Information

Publications10

  1. ncbi request reprint Coding and transformations in the olfactory system
    Naoshige Uchida
    Department of Molecular and Cellular Biology, Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138 email
    Annu Rev Neurosci 37:363-85. 2014
    ..Together, these studies suggest that the relative timing of neuronal activity in the OB conveys odor information and that neural circuits in the PC possess various mechanisms to decode temporal patterns of OB input. ..
  2. pmc Olfactory cortical neurons read out a relative time code in the olfactory bulb
    Rafi Haddad
    Center for Brain Science, Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, USA
    Nat Neurosci 16:949-57. 2013
    ..Thus, the brain can transform a relative time code in the periphery into a firing rate-based representation in central brain areas, providing evidence for the relevance of a relative time-based code in the olfactory bulb. ..
  3. pmc The dorsomedial striatum encodes net expected return, critical for energizing performance vigor
    Alice Y Wang
    Center for Brain Science, Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, USA
    Nat Neurosci 16:639-47. 2013
    ..The lesions, however, spared choice biases. Neuronal recordings showed that the DMS is enriched in net value-coding neurons. In sum, the DMS encodes one's net expected return, which drives the general motivation to perform...
  4. pmc Neuron-type-specific signals for reward and punishment in the ventral tegmental area
    Jeremiah Y Cohen
    Department of Molecular and Cellular Biology, Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138, USA
    Nature 482:85-8. 2012
    ..These results show that VTA GABAergic neurons signal expected reward, a key variable for dopaminergic neurons to calculate reward prediction error...
  5. ncbi request reprint Division of labor for division: inhibitory interneurons with different spatial landscapes in the olfactory system
    Naoshige Uchida
    Center for Brain Science, Department of Molecular and Cellular Biology, 16 Divinity Avenue, Cambridge, MA 02138, USA Electronic address
    Neuron 80:1106-9. 2013
    ..In this issue of Neuron, two studies, Kato et al. (2013) and Miyamichi et al. (2013), suggest that parvalbumin-positive interneurons in the olfactory bulb play a role in this process. ..
  6. doi request reprint Whole-brain mapping of direct inputs to midbrain dopamine neurons
    Mitsuko Watabe-Uchida
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Neuron 74:858-73. 2012
    ..Neuron-type-specific connectivity lays a foundation for studying how dopamine neurons compute outputs...
  7. pmc Odor representations in olfactory cortex: distributed rate coding and decorrelated population activity
    Keiji Miura
    Center for Brain Science, Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA
    Neuron 74:1087-98. 2012
    ..These findings demonstrate profound transformations in the dynamics of odor representations from the olfactory bulb to cortex and reveal likely substrates for odor-guided decisions...
  8. pmc An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger
    Michael J Krashes
    1 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA 2 Diabetes, Endocrinology and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA M J K National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland 21224, USA M J K Cardiovascular and Metabolic Diseases, Pfizer, 610 Main Street, Cambridge, Massachusetts 02139, USA B P S Division of Pediatric Endocrinology, Departments of Pediatrics, University of Michigan, Ann Arbor, Michigan 48105, USA D P O Cardiovascular and Metabolic Diseases, Novartis Institutes for BioMedical Research, 100 Technology Square, Cambridge, Massachusetts 02139, USA L V 3
    Nature 507:238-42. 2014
    ..Conversely, acute inhibition in mice with caloric-deficiency-induced hunger decreases feeding. Discovery of these afferent neurons capable of triggering hunger advances understanding of how this intense motivational state is regulated. ..
  9. doi request reprint Robust odor coding via inhalation-coupled transient activity in the mammalian olfactory bulb
    Kevin M Cury
    Department of Molecular and Cellular Biology, Harvard University, Center for Brain Science, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Neuron 68:570-85. 2010
    ..These results suggest that inhalation-coupled transient activity forms a robust neural code that is invariant to changes in respiration behavior...
  10. pmc Opening the black box: dopamine, predictions, and learning
    Neir Eshel
    Center for Brain Science, Department of Molecular and Cellular Biology, Harvard University, 16 Divinity Avenue, Cambridge, MA 02138, USA
    Trends Cogn Sci 17:430-1. 2013
    ..Whether these signals are sufficient for associative learning, however, remains untested. A recent study used optogenetics in a classic behavioral paradigm to confirm the role of dopamine prediction errors in learning. ..