M T Tsuang

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Genes, environment and schizophrenia
    M T Tsuang
    Harvard Medical School, Department of Psychiatry at Massachusetts Mental Health Center, 74 Fenwood Road, Boston, MA 02115, USA
    Br J Psychiatry Suppl 40:s18-24. 2001
  2. ncbi request reprint Diagnostic accuracy and linkage analysis: how useful are schizophrenia spectrum phenotypes?
    S V Faraone
    Harvard Medical School Department of Psychiatry, Massachusetts Mental Health Center, Boston, USA
    Am J Psychiatry 152:1286-90. 1995
  3. ncbi request reprint Impact of genetic vulnerability and hypoxia on overall intelligence by age 7 in offspring at high risk for schizophrenia compared with affective psychoses
    J M Goldstein
    Department of Psychiatry at Massachusetts Mental Health Center, Boston 02115, USA
    Schizophr Bull 26:323-34. 2000
  4. ncbi request reprint Reduced subcortical brain volumes in nonpsychotic siblings of schizophrenic patients: a pilot magnetic resonance imaging study
    L J Seidman
    Department of Psychiatry at Massachusetts Mental Health Center, Harvard Medical School, Boston 02115, USA
    Am J Med Genet 74:507-14. 1997
  5. ncbi request reprint Association of neuropsychological vulnerability markers in relatives of schizophrenic patients
    R Toomey
    Harvard Institute of Psychiatric Epidemiology and Genetics, Boston, MA, USA
    Schizophr Res 31:89-98. 1998
  6. ncbi request reprint The genetics of schizophrenia
    M T Tsuang
    Harvard Medical School, Department of Psychiatry at the Massachusetts Mental Health Center, 74 Fenwood Road, Boston, MA 02115, USA
    Curr Psychiatry Rep 1:20-4. 1999
  7. pmc Neuropsychological performance and family history in children at age 7 who develop adult schizophrenia or bipolar psychosis in the New England Family Studies
    L J Seidman
    Department of Psychiatry, Harvard Medical School, Massachusetts Mental Health Center Division of Public Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Psychol Med 43:119-31. 2013
  8. ncbi request reprint The Harvard Twin Study of Substance Abuse: what we have learned
    M T Tsuang
    Harvard Institute of Psychiatric Epidemiology and Genetics, Boston, MA 02115, USA
    Harv Rev Psychiatry 9:267-79. 2001
  9. ncbi request reprint The relationship of prenatal and perinatal complications to cognitive functioning at age 7 in the New England Cohorts of the National Collaborative Perinatal Project
    L J Seidman
    Harvard Medical School, Department of Psychiatry at Massachusetts Mental Health Center, Boston 02115, USA
    Schizophr Bull 26:309-21. 2000
  10. ncbi request reprint Concurrent validation of schizotaxia: a pilot study
    W S Stone
    Department of Psychiatry at Massachusetts Mental Health Center, Harvard Medical School, 74 Fenwood Road, Boston, MA 02115, USA
    Biol Psychiatry 50:434-40. 2001

Detail Information

Publications16

  1. ncbi request reprint Genes, environment and schizophrenia
    M T Tsuang
    Harvard Medical School, Department of Psychiatry at Massachusetts Mental Health Center, 74 Fenwood Road, Boston, MA 02115, USA
    Br J Psychiatry Suppl 40:s18-24. 2001
    ..Nevertheless, it remains clear that environmental factors both add to and interact with genetic factors to produce the disorder...
  2. ncbi request reprint Diagnostic accuracy and linkage analysis: how useful are schizophrenia spectrum phenotypes?
    S V Faraone
    Harvard Medical School Department of Psychiatry, Massachusetts Mental Health Center, Boston, USA
    Am J Psychiatry 152:1286-90. 1995
    ..However, most of these studies do not address a key measurement question: does the diagnostic accuracy of these spectrum classifications warrant their use in genetic linkage studies of schizophrenia?..
  3. ncbi request reprint Impact of genetic vulnerability and hypoxia on overall intelligence by age 7 in offspring at high risk for schizophrenia compared with affective psychoses
    J M Goldstein
    Department of Psychiatry at Massachusetts Mental Health Center, Boston 02115, USA
    Schizophr Bull 26:323-34. 2000
    ..Specificity of the effects for schizophrenia compared with affective psychoses and sex effects were also tested. Low IQ at age 7 was significantly associated with genetic vulnerability to psychoses, in particular with schizophrenia...
  4. ncbi request reprint Reduced subcortical brain volumes in nonpsychotic siblings of schizophrenic patients: a pilot magnetic resonance imaging study
    L J Seidman
    Department of Psychiatry at Massachusetts Mental Health Center, Harvard Medical School, Boston 02115, USA
    Am J Med Genet 74:507-14. 1997
    ..If replicated in a larger sample including both sexes, these results would suggest that the genetic liability to schizophrenia is also expressed as structural brain abnormalities...
  5. ncbi request reprint Association of neuropsychological vulnerability markers in relatives of schizophrenic patients
    R Toomey
    Harvard Institute of Psychiatric Epidemiology and Genetics, Boston, MA, USA
    Schizophr Res 31:89-98. 1998
    ..We discuss how the use of multiple risk indicators may help us better identify those relatives that carry the schizophrenia genotype...
  6. ncbi request reprint The genetics of schizophrenia
    M T Tsuang
    Harvard Medical School, Department of Psychiatry at the Massachusetts Mental Health Center, 74 Fenwood Road, Boston, MA 02115, USA
    Curr Psychiatry Rep 1:20-4. 1999
    ..The potential importance of schizotaxia, or similar concepts, for use in genetic studies, is discussed...
  7. pmc Neuropsychological performance and family history in children at age 7 who develop adult schizophrenia or bipolar psychosis in the New England Family Studies
    L J Seidman
    Department of Psychiatry, Harvard Medical School, Massachusetts Mental Health Center Division of Public Psychiatry, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Psychol Med 43:119-31. 2013
    ..We evaluated the specificity and impact of family history (FH) of psychosis on pre-morbid neuropsychological functioning...
  8. ncbi request reprint The Harvard Twin Study of Substance Abuse: what we have learned
    M T Tsuang
    Harvard Institute of Psychiatric Epidemiology and Genetics, Boston, MA 02115, USA
    Harv Rev Psychiatry 9:267-79. 2001
    ..Our results, thus far, indicate a complex pattern of genetic and environmental influences on substance use and abuse...
  9. ncbi request reprint The relationship of prenatal and perinatal complications to cognitive functioning at age 7 in the New England Cohorts of the National Collaborative Perinatal Project
    L J Seidman
    Harvard Medical School, Department of Psychiatry at Massachusetts Mental Health Center, Boston 02115, USA
    Schizophr Bull 26:309-21. 2000
    ..Future studies will evaluate the effects of specific PPCs and genetic risk factors for psychosis on cognitive functioning in childhood...
  10. ncbi request reprint Concurrent validation of schizotaxia: a pilot study
    W S Stone
    Department of Psychiatry at Massachusetts Mental Health Center, Harvard Medical School, 74 Fenwood Road, Boston, MA 02115, USA
    Biol Psychiatry 50:434-40. 2001
    ....
  11. ncbi request reprint Normal sexual dimorphism of the adult human brain assessed by in vivo magnetic resonance imaging
    J M Goldstein
    Harvard Medical School Department of Psychiatry at Massachusetts Mental Health Center, Boston, MA 02115, USA
    Cereb Cortex 11:490-7. 2001
    ..These findings have implications for developmental studies that would directly test hypotheses about mechanisms relating sex steroid hormones to sexual dimorphisms in humans...
  12. ncbi request reprint Genetic association analysis of behavioral inhibition using candidate loci from mouse models
    J W Smoller
    Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Am J Med Genet 105:226-35. 2001
    ..This study illustrates the potential utility of using candidate genes derived from mouse models to dissect the genetic basis of BI, a possible intermediate phenotype for panic and phobic disorders...
  13. ncbi request reprint A functional magnetic resonance imaging study of auditory vigilance with low and high information processing demands
    L J Seidman
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    Neuropsychology 12:505-18. 1998
    ..Performance and degree of activation was associated with an estimate of IQ. Further research should clarify the contributions of working memory and interference filtering to the activated network...
  14. ncbi request reprint Meta-analysis identifies an association between the dopamine D2 receptor gene and schizophrenia
    S J Glatt
    Department of Psychiatry, Harvard Medical School at Massachusetts Mental Health Center, Boston, MA 02115, USA
    Mol Psychiatry 8:911-5. 2003
    ..Although more family-based studies are needed to confirm this relation, our results provide strong evidence that DRD2 influences susceptibility to schizophrenia...
  15. ncbi request reprint Neuropsychological consequences of regular marijuana use: a twin study
    M J Lyons
    Psychology Department, Boston University, Boston, MA 02215, USA
    Psychol Med 34:1239-50. 2004
    ..A major methodological limitation of prior studies is the inability to determine whether differences between users and non-users are due to differences in genetic vulnerability preceding drug use or due to the effects of the drug...
  16. ncbi request reprint Genome scan of European-American schizophrenia pedigrees: results of the NIMH Genetics Initiative and Millennium Consortium
    S V Faraone
    Department of Psychiatry, Harvard Medical School at Massachusetts Mental Health Center, Boston, USA
    Am J Med Genet 81:290-5. 1998
    ..4, P = .0004) and its neighbor, D10S582 (NPL Z = 3.2, P = .0006)...