E N Tsitsikov

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint TRAF1 is a negative regulator of TNF signaling. enhanced TNF signaling in TRAF1-deficient mice
    E N Tsitsikov
    Division of Immunology, Children s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Immunity 15:647-57. 2001
  2. pmc Impaired CD19 expression and signaling, enhanced antibody response to type II T independent antigen and reduction of B-1 cells in CD81-deficient mice
    E N Tsitsikov
    Children s Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 94:10844-9. 1997
  3. ncbi request reprint The mouse genome contains two expressed intronless retroposed pseudogenes for the sentrin/sumo-1/PIC1 conjugating enzyme Ubc9
    A V Tsytsykova
    Children s Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA
    Mol Immunol 35:1057-67. 1998

Collaborators

Detail Information

Publications3

  1. ncbi request reprint TRAF1 is a negative regulator of TNF signaling. enhanced TNF signaling in TRAF1-deficient mice
    E N Tsitsikov
    Division of Immunology, Children s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Immunity 15:647-57. 2001
    ..This TNF effect was mediated by TNFR2 (p75) but not by TNFR1 (p55). Furthermore, skin from TRAF1(-/-) mice was hypersensitive to TNF-induced necrosis. These findings suggest that TRAF1 is a negative regulator of TNF signaling...
  2. pmc Impaired CD19 expression and signaling, enhanced antibody response to type II T independent antigen and reduction of B-1 cells in CD81-deficient mice
    E N Tsitsikov
    Children s Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 94:10844-9. 1997
    ..CD81-deficient mice had increased serum IgM and IgA and an exaggerated antibody response to the type II T independent antigen TNP-Ficoll. These results suggest that CD81 is important for CD19 signaling and B cell function...
  3. ncbi request reprint The mouse genome contains two expressed intronless retroposed pseudogenes for the sentrin/sumo-1/PIC1 conjugating enzyme Ubc9
    A V Tsytsykova
    Children s Hospital and Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA
    Mol Immunol 35:1057-67. 1998
    ..These results suggest that ubc9-psi1 and ubc9-psi2 encode for proteins that may interact with targets that differ from those recognized by ubc-9...