Alexander C Tsai

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Directly observed antidepressant medication treatment and HIV outcomes among homeless and marginally housed HIV-positive adults: a randomized controlled trial
    Alexander C Tsai
    Langley Porter Psychiatric Institute, University of California, San Francisco, CA, USA
    Am J Public Health 103:308-15. 2013
  2. pmc Is food insecurity associated with HIV risk? Cross-sectional evidence from sexually active women in Brazil
    Alexander C Tsai
    Robert Wood Johnson Health and Society Scholars Program, Harvard University, Cambridge, Massachusetts, USA
    PLoS Med 9:e1001203. 2012
  3. pmc Medical evidence of human rights violations against non-Arabic-speaking civilians in Darfur: a cross-sectional study
    Alexander C Tsai
    Robert Wood Johnson Health and Society Scholars Program, Harvard University, Cambridge, Massachusetts, USA
    PLoS Med 9:e1001198. 2012
  4. pmc Food insecurity, depression and the modifying role of social support among people living with HIV/AIDS in rural Uganda
    Alexander C Tsai
    Robert Wood Johnson Health and Society Scholars Program, Harvard University, MA, USA
    Soc Sci Med 74:2012-9. 2012
  5. pmc The social context of food insecurity among persons living with HIV/AIDS in rural Uganda
    Alexander C Tsai
    Robert Wood Johnson Health and Society Scholars Program, Harvard University, Cambridge, MA, United States
    Soc Sci Med 73:1717-24. 2011
  6. doi request reprint Proximate context of gender-unequal norms and women's HIV risk in sub-Saharan Africa
    Alexander C Tsai
    Robert Wood Johnson Health and Society Scholars Program, Harvard University, Cambridge, Massachusetts, USA
    AIDS 26:381-6. 2012
  7. pmc Prevalence and correlates of forced sex perpetration and victimization in Botswana and Swaziland
    Alexander C Tsai
    Department of Psychiatry, University of California, San Francisco, USA
    Am J Public Health 101:1068-74. 2011
  8. pmc How does antiretroviral treatment attenuate the stigma of HIV? Evidence from a cohort study in rural Uganda
    Alexander C Tsai
    Chester M Pierce, MD Division of Global Psychiatry, Department of Psychiatry, Massachusetts General Hospital MGH, Center for Global Health, Room 1529 E3, 100 Cambridge Street, 15th Floor, Boston, MA, 02114, USA
    AIDS Behav 17:2725-31. 2013
  9. pmc Does effective depression treatment alone reduce secondary HIV transmission risk? Equivocal findings from a randomized controlled trial
    Alexander C Tsai
    Chester M Pierce, MD Division of Global Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
    AIDS Behav 17:2765-72. 2013
  10. pmc No association found between traditional healer use and delayed antiretroviral initiation in rural Uganda
    RUSSELL H HORWITZ
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
    AIDS Behav 17:260-5. 2013

Detail Information

Publications38

  1. pmc Directly observed antidepressant medication treatment and HIV outcomes among homeless and marginally housed HIV-positive adults: a randomized controlled trial
    Alexander C Tsai
    Langley Porter Psychiatric Institute, University of California, San Francisco, CA, USA
    Am J Public Health 103:308-15. 2013
    ..We assessed whether directly observed fluoxetine treatment reduced depression symptom severity and improved HIV outcomes among homeless and marginally housed HIV-positive adults in San Francisco, California, from 2002 to 2008...
  2. pmc Is food insecurity associated with HIV risk? Cross-sectional evidence from sexually active women in Brazil
    Alexander C Tsai
    Robert Wood Johnson Health and Society Scholars Program, Harvard University, Cambridge, Massachusetts, USA
    PLoS Med 9:e1001203. 2012
    ..We used data from a national survey of Brazilian women to estimate the relationship between food insecurity and HIV risk...
  3. pmc Medical evidence of human rights violations against non-Arabic-speaking civilians in Darfur: a cross-sectional study
    Alexander C Tsai
    Robert Wood Johnson Health and Society Scholars Program, Harvard University, Cambridge, Massachusetts, USA
    PLoS Med 9:e1001198. 2012
    ....
  4. pmc Food insecurity, depression and the modifying role of social support among people living with HIV/AIDS in rural Uganda
    Alexander C Tsai
    Robert Wood Johnson Health and Society Scholars Program, Harvard University, MA, USA
    Soc Sci Med 74:2012-9. 2012
    ..Interventions aimed at improving food security and strengthening instrumental social support may have synergistic beneficial effects on both mental health and HIV outcomes among PLWHA in resource-limited settings...
  5. pmc The social context of food insecurity among persons living with HIV/AIDS in rural Uganda
    Alexander C Tsai
    Robert Wood Johnson Health and Society Scholars Program, Harvard University, Cambridge, MA, United States
    Soc Sci Med 73:1717-24. 2011
    ..These findings also indicate that structural interventions to improve social support and/or decrease HIV-related stigma may also improve the food security of PLWHA...
  6. doi request reprint Proximate context of gender-unequal norms and women's HIV risk in sub-Saharan Africa
    Alexander C Tsai
    Robert Wood Johnson Health and Society Scholars Program, Harvard University, Cambridge, Massachusetts, USA
    AIDS 26:381-6. 2012
    ..To determine whether the proximate context of gender-unequal norms about violence against women undermines women's ability to negotiate condom use in sexual relationships...
  7. pmc Prevalence and correlates of forced sex perpetration and victimization in Botswana and Swaziland
    Alexander C Tsai
    Department of Psychiatry, University of California, San Francisco, USA
    Am J Public Health 101:1068-74. 2011
    ..We sought to identify correlates of forced sex perpetration among men and victimization among women in Botswana and Swaziland...
  8. pmc How does antiretroviral treatment attenuate the stigma of HIV? Evidence from a cohort study in rural Uganda
    Alexander C Tsai
    Chester M Pierce, MD Division of Global Psychiatry, Department of Psychiatry, Massachusetts General Hospital MGH, Center for Global Health, Room 1529 E3, 100 Cambridge Street, 15th Floor, Boston, MA, 02114, USA
    AIDS Behav 17:2725-31. 2013
    ..3; P = 0.03), and appeared to be driven by ART-induced improvements in HIV symptom burden, physical and psychological wellbeing, and depression symptom severity...
  9. pmc Does effective depression treatment alone reduce secondary HIV transmission risk? Equivocal findings from a randomized controlled trial
    Alexander C Tsai
    Chester M Pierce, MD Division of Global Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
    AIDS Behav 17:2765-72. 2013
    ..Mental health interventions may need to combine depression treatment with specific skills training in order to achieve durable impacts on HIV prevention outcomes...
  10. pmc No association found between traditional healer use and delayed antiretroviral initiation in rural Uganda
    RUSSELL H HORWITZ
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
    AIDS Behav 17:260-5. 2013
    ..These findings suggest that TH/SC use does not delay initiation of ART...
  11. pmc Internalized stigma, social distance, and disclosure of HIV seropositivity in rural Uganda
    Alexander C Tsai
    Chester M Pierce, MD Division of Global Psychiatry, Department of Psychiatry, Massachusetts General Hospital MGH, Boston, MA, USA
    Ann Behav Med 46:285-94. 2013
    ..HIV is highly stigmatized, compromising both treatment and prevention in resource-limited settings...
  12. pmc Evidence for the reliability and validity of the internalized AIDS-related stigma scale in rural Uganda
    Alexander C Tsai
    Center for Global Health, Massachusetts General Hospital, Room 1529 E3, 100 Cambridge Street, 15th Floor, Boston, MA 02114, USA
    AIDS Behav 17:427-33. 2013
    ..Taken together, these findings suggest that the Internalized AIDS-Related Stigma Scale may be a useful tool for socio-behavioral HIV research...
  13. pmc Declining prevalence of probable depression among patients presenting for antiretroviral therapy in rural Uganda: the role of early treatment initiation
    Brian T Chan
    Division of Infectious Diseases, Massachusetts General Hospital, 55 Fruit Street GRJ 504, 02114 2696, Boston, MA, USA
    AIDS Behav 19:19-26. 2015
    ..This trend remained statistically significant after inclusion of baseline socio-demographic characteristics to the model and appeared to be driven by improved physical health scores, but not CD4 count or BMI...
  14. pmc Reversal of the Kynurenine pathway of tryptophan catabolism may improve depression in ART-treated HIV-infected Ugandans
    Priscilla Martinez
    Norwegian Center for Addiction Research, University of Oslo, Oslo, Norway Alcohol Research Group, School of Public Health, University of California, Berkeley, CA Center for Global Health, Massachusetts General Hospital, Boston, MA Division of Global Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, MA Mbarara University of Science and Technology, Mbarara, Uganda University of California at San Francisco, San Francisco, CA Division of HIV AIDS, San Francisco General Hospital, University of California San Francisco, CA Department of Global Health and Social Medicine, Harvard Medical School, Boston, MA Department of Global Health and Population, Harvard School of Public Health, Boston, MA and Ragon Institute of Massachusetts General Hospital, MIT and Harvard, Boston, MA
    J Acquir Immune Defic Syndr 65:456-62. 2014
    ....
  15. pmc Sexual relationship power and depression among HIV-infected women in Rural Uganda
    Abigail M Hatcher
    Division of HIV AIDS, Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    PLoS ONE 7:e49821. 2012
    ..Low sexual relationship power also contributes to HIV risk, but there is limited understanding of how it relates to mental health among HIV-infected women...
  16. pmc Food insecurity is associated with morbidity and patterns of healthcare utilization among HIV-infected individuals in a resource-poor setting
    Sheri D Weiser
    Division of HIV AIDS, San Francisco General Hospital, University of California, San Francisco, 94143, USA
    AIDS 26:67-75. 2012
    ..We undertook a longitudinal study in rural Uganda to understand the association of food insecurity with morbidity and patterns of healthcare utilization among HIV-infected individuals enrolled in an antiretroviral therapy program...
  17. pmc Changes in food insecurity, nutritional status, and physical health status after antiretroviral therapy initiation in rural Uganda
    Sheri D Weiser
    Department of Medicine, Division of HIV AIDS, San Francisco General Hospital, University of California San Francisco, San Francisco, CA 94110, USA
    J Acquir Immune Defic Syndr 61:179-86. 2012
    ..To investigate whether time on antiretroviral therapy (ART) is associated with improvements in food security and nutritional status, and the extent to which associations are mediated by improved physical health status...
  18. pmc The dynamic relationship between social support and HIV-related stigma in rural Uganda
    Sae Takada
    Harvard Medical School, Boston, MA, USA
    Ann Behav Med 48:26-37. 2014
    ..Cross-sectional studies show that human immunodeficiency virus (HIV) stigma is negatively correlated with social support...
  19. doi request reprint The factor structure and presentation of depression among HIV-positive adults in Uganda
    Christina Psaros
    Department of Psychiatry, Behavioral Medicine Service, Massachusetts General Hospital, One Bowdoin Square, 7th Floor, Boston, MA, 02114, USA
    AIDS Behav 19:27-33. 2015
    ..Somatic-cognitive symptoms of depression and disengagement from life's activities appear to be distinct components of depression in this sample. Consideration of somatic items may be valuable in identifying depression in this setting...
  20. pmc A marginal structural model to estimate the causal effect of antidepressant medication treatment on viral suppression among homeless and marginally housed persons with HIV
    Alexander C Tsai
    Langley Porter Psychiatric Institute, University of California at San Francisco, USA
    Arch Gen Psychiatry 67:1282-90. 2010
    ..Application of marginal structural modeling to longitudinal observation data can, under certain assumptions, approximate the findings of a randomized controlled trial...
  21. pmc Persistent HIV-related stigma in rural Uganda during a period of increasing HIV incidence despite treatment expansion
    Brian T Chan
    aDivision of Infectious Diseases, Massachusetts General Hospital bDivision of Infectious Diseases, Brigham and Women s Hospital cHarvard Medical School, Boston, Massachusetts dDivision of HIV AIDS, San Francisco General Hospital, University of California at San Francisco UCSF eCenter for AIDS Prevention Studies, UCSF, San Francisco, California, USA fEpicentre, Mbarara, Uganda gMassachusetts General Hospital Center for Global Health, Boston, Massachusetts hDepartment of Epidemiology and Biostatistics, UCSF, San Francisco, California iDivision of Infectious Diseases, Beth Israel Deaconess Medical Center jFenway Health, Boston, Massachusetts, USA kMbarara University of Science and Technology, Mbarara, Uganda lChester M Pierce, MD Division of Global Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
    AIDS 29:83-90. 2015
    ..Programme implementers have argued that the increasing availability of antiretroviral therapy (ART) will reduce the stigma of HIV. We analyzed data from Uganda to assess how HIV-related stigma has changed during a period of ART expansion...
  22. pmc CD4+ cell count at antiretroviral therapy initiation and economic restoration in rural Uganda
    Atheendar S Venkataramani
    aDepartment of Medicine bCenter for Global Health, Massachusetts General Hospital, Boston, Massachusetts cDepartment of Health Policy and Management, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA dMédecins Sans Frontières Epicentre eMbarara University of Science and Technology, Mbarara, Uganda fUniversity of California, San Francisco School of Medicine, San Francisco, California gRagon Institute of MGH, MIT, and Harvard University hDepartment of Global Health and Population, Harvard School of Public Health iDepartment of Psychiatry, Massachusetts General Hospital jRobert Wood Johnson Health and Society Scholars Program, Harvard University, Boston, Massachusetts, USA
    AIDS 28:1221-6. 2014
    ..To determine whether earlier initiation of antiretroviral therapy (ART) is associated with better economic outcomes...
  23. doi request reprint Longitudinal assessment of associations between food insecurity, antiretroviral adherence and HIV treatment outcomes in rural Uganda
    Sheri D Weiser
    aDivision of HIV AIDS, San Francisco General Hospital, University of California, San Francisco UCSF, San Francisco bDepartment of Health Policy and Management, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, California cDepartment of Health Promotion, Education, and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina dMassachusetts General Hospital Center for Global Health, Boston, Massachusetts, USA eMbarara University of Science and Technology Mbarara, Uganda fUnited Nations World Food Programme, Rome, Italy gDepartment of Epidemiology and Biostatistics, UCSF, San Francisco, California hRagon Institute of MGH, MIT and Harvard University iDepartment of Global Health and Social Equity, Harvard Medical School jDepartment of Global Health and Populations, Harvard School of Public Health, Boston, Massachusetts, USA
    AIDS 28:115-20. 2014
    ..We undertook a longitudinal study in rural Uganda to estimate the associations between food insecurity and HIV treatment outcomes...
  24. pmc Harnessing poverty alleviation to reduce the stigma of HIV in Sub-Saharan Africa
    Alexander C Tsai
    Chester M Pierce, MD Division of Global Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, United States of America Harvard Medical School, Boston, Massachusetts, United States of America Center for Global Health, Massachusetts General Hospital, Boston, Massachusetts, United States of America
    PLoS Med 10:e1001557. 2013
    ..Alexander Tsai and colleagues highlight the complex relationship between poverty and HIV stigma in sub-Saharan Africa, and discuss possible ways to break the cycle. Please see later in the article for the Editors' Summary. ..
  25. pmc Treatment as long-term prevention: sustained reduction in HIV sexual transmission risk with use of antiretroviral therapy in rural Uganda
    Mark J Siedner
    aMassachusetts General Hospital, Center for Global Health, Boston, Massachusetts, USA bMbarara University of Science and Technology, Mbarara, Uganda cChester M Pierce MD Division of Global Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA dUniversity of California, San Francisco, California, USA eRagon Institute of Massachusetts General Hospital MIT and Harvard, and Harvard Medical School, Boston, Massachusetts, USA
    AIDS 28:267-71. 2014
    ..We sought to measure the frequency and correlates of periods of transmission risk among individuals taking ART during multiple years of observation in rural, southwestern Uganda...
  26. pmc Sexual relationship power and malnutrition among HIV-positive women in rural Uganda
    Mark J Siedner
    Department of Infectious Disease, Massachusetts General Hospital, Harvard Medical School, Boston, 02114, USA
    AIDS Behav 16:1542-8. 2012
    ..Targeted interventions to improve intimate partner relationship equality should be explored to improve health status among women living with HIV in rural Africa...
  27. pmc Conceptual framework for understanding the bidirectional links between food insecurity and HIV/AIDS
    Sheri D Weiser
    Division of HIV AIDS, San Francisco General Hospital, USA
    Am J Clin Nutr 94:1729S-1739S. 2011
    ..More research on the relative importance of each of these pathways is warranted because effective interventions to reduce food insecurity and HIV depend on a rigorous understanding of these multifaceted relationships...
  28. pmc Impact of HIV-related stigma on treatment adherence: systematic review and meta-synthesis
    Ingrid T Katz
    Connors Center for Women s Health and Gender Biology, Brigham and Women s Hospital, Boston, MA, United States Center for Global Health, Massachusetts General Hospital, Boston, MA, United States Harvard Medical School, Boston, MA, United States
    J Int AIDS Soc 16:18640. 2013
    ..We therefore undertook this review to systematically assess the relationship between HIV-related stigma and ART adherence...
  29. pmc Depression during pregnancy and the postpartum among HIV-infected women on antiretroviral therapy in Uganda
    Angela Kaida
    Faculty of Health Sciences, Simon Fraser University, Burnaby, Canada Center for Global Health and Division of Infectious Disease, Massachusetts General Hospital, Boston, MA Mbarara University of Science and Technology, Mbarara, Uganda Harvard Medical School, Boston, MA Division of Global Psychiatry, Department of Psychiatry, Massachusetts General Hospital, Boston, MA Center for Global Health, Massachusetts General Hospital, Boston, MA School of Population and Public Health, University of British Columbia, Vancouver, Canada Department of Psychiatry, Massachusetts General Hospital Harvard Medical School, Boston, MA Epicentre Mbarara, Mbarara, Uganda Center for Global Health and Department of Medicine, Massachusetts General Hospital, Boston, MA and University of California, San Francisco UCSF, San Francisco, CA
    J Acquir Immune Defic Syndr 67:S179-87. 2014
    ..Antiretroviral therapy (ART) is associated with lower depression symptom severity but the uniformity of effect through pregnancy and postpartum periods is unknown...
  30. pmc A qualitative analysis of factors influencing HPV vaccine uptake in Soweto, South Africa among adolescents and their caregivers
    Ingrid T Katz
    Brigham and Women s Hospital, Boston, Massachusetts, United States of America Harvard Medical School, Boston, Massachusetts, United States of America Massachusetts General Hospital Center for Global Health, Boston, Massachusetts, United States of America
    PLoS ONE 8:e72094. 2013
    ..Given the importance of psycho-social forces in vaccine uptake, we sought to elucidate factors influencing HPV vaccination among a sample of low-income South African adolescents receiving the vaccine for the first time in Soweto...
  31. pmc Urinary incontinence, depression, and economic outcomes in a cohort of women between the ages of 54 and 65 years
    Kristin J Hung
    Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Harvard Medical School, the Division of Global Psychiatry, Department of Psychiatry, and the Center for Global Health, Massachusetts General Hospital, Boston, Massachusetts, and the Mbarara University for Science and Technology, Mbarara Uganda
    Obstet Gynecol 123:822-7. 2014
    ..To estimate the association between urinary incontinence (UI) and probable depression, work disability, and workforce exit...
  32. pmc Reliability and validity of instruments for assessing perinatal depression in African settings: systematic review and meta-analysis
    Alexander C Tsai
    Center for Global Health, Massachusetts General Hospital, Boston, Massachusetts, United States of America Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, United States of America Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 8:e82521. 2013
    ..We systematically reviewed the evidence on the reliability and validity of instruments to assess perinatal depression in African settings...
  33. pmc Antenatal depression case finding by community health workers in South Africa: feasibility of a mobile phone application
    Alexander C Tsai
    Center for Global Health and Chester M Pierce, MD Division of Global Psychiatry, Massachusetts General Hospital, 100 Cambridge Street, 15th Floor, Boston, MA, 02114, USA
    Arch Womens Ment Health 17:423-31. 2014
    ..76 specificity for detecting probable antenatal depression. The comparability of the findings across the two studies suggests that it is feasible to use community health workers to conduct case finding for antenatal depression...
  34. pmc Population-based study of food insecurity and HIV transmission risk behaviors and symptoms of sexually transmitted infections among linked couples in Nepal
    Alexander C Tsai
    Chester M Pierce, MD Division of Global Psychiatry and Center for Global Health, Massachusetts General Hospital, Room 1529 E3, 100 Cambridge Street, 15th Floor, Boston, MA, 02114, USA
    AIDS Behav 18:2187-97. 2014
    ..These patterns were absent among men. Interventions targeting food insecurity may have beneficial implications for both HIV prevention and gender equity in Nepal. ..
  35. pmc Global health training in US graduate psychiatric education
    Alexander C Tsai
    Massachusetts General Hospital, Boston, MA, USA
    Acad Psychiatry 38:426-32. 2014
    ..We therefore sought to characterize the distribution of global health training opportunities in US graduate psychiatric education...
  36. doi request reprint Households with young children and use of freely distributed bednets in rural Madagascar
    Paul J Krezanoski
    Department of Medicine, Massachusetts General Hospital, Boston, MA, USA
    Int Health 6:29-34. 2014
    ..Malaria infections are the leading cause of death for children in Madagascar. Insecticide-treated bednets offer effective prevention, but it is unclear how well free bednet distribution programs reach young children...
  37. doi request reprint Community-level and individual-level influences of intimate partner violence on birth spacing in sub-Saharan Africa
    Kristin J Hung
    Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Obstet Gynecol 119:975-82. 2012
    ..To estimate the extent to which intimate partner violence (IPV), at the levels of the individual and the community, is associated with shortened interbirth intervals among women in sub-Saharan Africa...