Robert J Thomas

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Arousals in sleep-disordered breathing: patterns and implications
    Robert Joseph Thomas
    Sleep Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Sleep 26:1042-7. 2003
  2. ncbi request reprint Fatigue in the executive cortical network demonstrated in narcoleptics using functional magnetic resonance imaging--a preliminary study
    Robert J Thomas
    Division of Pulmonary Critical Care and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Sleep Med 6:399-406. 2005
  3. doi request reprint A pilot study of sleep, cognition, and respiration under 4 weeks of intermittent nocturnal hypoxia in adult humans
    Matthew D Weiss
    Beth Israel Deaconess Medical Center and Harvard Medical School, KB 023, Pulmonary Office, 330 Brookline Avenue, Boston, MA 02215, USA
    Sleep Med 10:739-45. 2009
  4. doi request reprint Probabilistic sleep architecture models in patients with and without sleep apnea
    Matt T Bianchi
    Neurology Department, Massachusetts General Hospital, Boston, MA 02114, USA
    J Sleep Res 21:330-41. 2012
  5. ncbi request reprint Mechanisms of arousal from sleep and their consequences
    Geoffrey S Gilmartin
    Beth Israel Deaconess Medical Center, Division of Pulmonary, Critical Care and Sleep Medicine, Boston, Massachusetts 02115, USA
    Curr Opin Pulm Med 10:468-74. 2004
  6. pmc Heritability of abnormalities in cardiopulmonary coupling in sleep apnea: use of an electrocardiogram-based technique
    Lamia H Ibrahim
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106 6003, USA
    Sleep 33:643-6. 2010
  7. pmc Classification algorithms for predicting sleepiness and sleep apnea severity
    Nathaniel A Eiseman
    Neurology Department, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    J Sleep Res 21:101-12. 2012
  8. pmc Electrocardiogram-based sleep spectrogram measures of sleep stability and glucose disposal in sleep disordered breathing
    Melanie S Pogach
    Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Sleep 35:139-48. 2012
  9. ncbi request reprint Recognition and management of complex sleep-disordered breathing
    Geoffrey S Gilmartin
    Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA
    Curr Opin Pulm Med 11:485-93. 2005
  10. ncbi request reprint Functional imaging of working memory in obstructive sleep-disordered breathing
    Robert J Thomas
    Division of Pulmonary Critical Care and Sleep Medicine, Department of Medicine, CC 866, Sleep Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Appl Physiol 98:2226-34. 2005

Detail Information

Publications21

  1. ncbi request reprint Arousals in sleep-disordered breathing: patterns and implications
    Robert Joseph Thomas
    Sleep Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Sleep 26:1042-7. 2003
    ..To describe the whole spectrum of electroencephalographic (EEG) transients associated with the termination and recovery of obstructed respiratory events and, thus, widen the recognized spectrum of arousal phenomena from sleep...
  2. ncbi request reprint Fatigue in the executive cortical network demonstrated in narcoleptics using functional magnetic resonance imaging--a preliminary study
    Robert J Thomas
    Division of Pulmonary Critical Care and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Sleep Med 6:399-406. 2005
    ..To demonstrate dynamic changes in cerebral functional activation during a working memory task in a state of severe excessive daytime sleepiness...
  3. doi request reprint A pilot study of sleep, cognition, and respiration under 4 weeks of intermittent nocturnal hypoxia in adult humans
    Matthew D Weiss
    Beth Israel Deaconess Medical Center and Harvard Medical School, KB 023, Pulmonary Office, 330 Brookline Avenue, Boston, MA 02215, USA
    Sleep Med 10:739-45. 2009
    ..A pilot study to examine the effects of intermittent nocturnal hypoxia on sleep, respiration and cognition in healthy adult humans...
  4. doi request reprint Probabilistic sleep architecture models in patients with and without sleep apnea
    Matt T Bianchi
    Neurology Department, Massachusetts General Hospital, Boston, MA 02114, USA
    J Sleep Res 21:330-41. 2012
    ..Markov sleep models may prove important for quantifying sleep disruption to provide objective metrics to correlate with endpoints ranging from sleepiness to cardiovascular morbidity...
  5. ncbi request reprint Mechanisms of arousal from sleep and their consequences
    Geoffrey S Gilmartin
    Beth Israel Deaconess Medical Center, Division of Pulmonary, Critical Care and Sleep Medicine, Boston, Massachusetts 02115, USA
    Curr Opin Pulm Med 10:468-74. 2004
    ..This review describes the recent insights into the nature of sleep and arousal and the particular insights gained in common disease states such as sleep-disordered breathing...
  6. pmc Heritability of abnormalities in cardiopulmonary coupling in sleep apnea: use of an electrocardiogram-based technique
    Lamia H Ibrahim
    Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106 6003, USA
    Sleep 33:643-6. 2010
    ..We evaluated the familial aggregation of distinctive spectrographic biomarkers of unstable sleep, related to elevated-low frequency cardiopulmonary coupling (e-LFC), to assess their utility in genetic studies...
  7. pmc Classification algorithms for predicting sleepiness and sleep apnea severity
    Nathaniel A Eiseman
    Neurology Department, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    J Sleep Res 21:101-12. 2012
    ....
  8. pmc Electrocardiogram-based sleep spectrogram measures of sleep stability and glucose disposal in sleep disordered breathing
    Melanie S Pogach
    Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Sleep 35:139-48. 2012
    ..The method allows improved characterization of the quality of stage 2 non-rapid eye movement (NREM) sleep...
  9. ncbi request reprint Recognition and management of complex sleep-disordered breathing
    Geoffrey S Gilmartin
    Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA
    Curr Opin Pulm Med 11:485-93. 2005
    ..This review will describe these recent advances in the literature and suggest a model for their incorporation into clinical practice...
  10. ncbi request reprint Functional imaging of working memory in obstructive sleep-disordered breathing
    Robert J Thomas
    Division of Pulmonary Critical Care and Sleep Medicine, Department of Medicine, CC 866, Sleep Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Appl Physiol 98:2226-34. 2005
    ..There may be dissociations between respiratory vs. cortical recovery and objective vs. subjective recovery. Hypofrontality may provide a plausible biological mechanism for a clinical overlap with disorders of mood and attention...
  11. ncbi request reprint An electrocardiogram-based technique to assess cardiopulmonary coupling during sleep
    Robert Joseph Thomas
    Sleep Unit, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Sleep 28:1151-61. 2005
    ..To evaluate a new automated measure of cardiopulmonary coupling during sleep using a single-lead electrocardiographic signal...
  12. ncbi request reprint Low-concentration carbon dioxide is an effective adjunct to positive airway pressure in the treatment of refractory mixed central and obstructive sleep-disordered breathing
    Robert Joseph Thomas
    Department of Medicine, Division of Pulmonary, Critcal Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Sleep 28:69-77. 2005
    ..To assess the efficacy of added carbon dioxide as adjunctive therapy to positive airway pressure-refractory mixed obstructive and central sleep-disordered breathing, using a prototype device-the positive airway pressure gas modulator...
  13. pmc Prevalent hypertension and stroke in the Sleep Heart Health Study: association with an ECG-derived spectrographic marker of cardiopulmonary coupling
    Robert Joseph Thomas
    Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Sleep 32:897-904. 2009
    ..This study assesses, at a population level, the associations of this spectrographic biomarker with prevalent cardiovascular disease using the Sleep Heart Health Study (SHHS)-I dataset...
  14. ncbi request reprint Effect of added dead space to positive airway pressure for treatment of complex sleep-disordered breathing
    Robert Joseph Thomas
    CC 866, Sleep Unit, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Sleep Med 6:177-8. 2005
  15. pmc Differentiating obstructive from central and complex sleep apnea using an automated electrocardiogram-based method
    Robert Joseph Thomas
    Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center Boston, MA 02215, USA
    Sleep 30:1756-69. 2007
    ..The objective of this study was to assess the utility of an electrocardiogram (ECG)-based cardiopulmonary coupling technique to distinguish obstructive from central or complex sleep apnea...
  16. pmc Nocturnal hypoxia exposure with simulated altitude for 14 days does not significantly alter working memory or vigilance in humans
    Robert Joseph Thomas
    Beth Israel Deaconess Medical School and Harvard Medical School, Boston, MA 02215, USA
    Sleep 30:1195-203. 2007
    ..To assess the effect of 2 weeks of nocturnal hypoxia exposure using simulated altitude on attention and working memory in healthy adult humans...
  17. ncbi request reprint Cyclic alternating pattern in the electroencephalogram: what is its clinical utility?
    Robert Joseph Thomas
    Division ofPulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Sleep 30:553-5. 2007
  18. ncbi request reprint Modafinil activates cortical and subcortical sites in the sleep-deprived state
    Robert Joseph Thomas
    Medicine Division of Pulmonary, Critical Care and Sleep, Beth Israel Deaconess Medical Center, Boston, 02215, USA
    Sleep 29:1471-81. 2006
    ..SUBJECT OBJECTIVES: To assess the effect of the wake-promoting drug modafinil on working memory and brain activation in the executive network, following a single night of sleep deprivation...
  19. ncbi request reprint Obstructive sleep-disordered breathing with a dominant cyclic alternating pattern--a recognizable polysomnographic variant with practical clinical implications
    Robert J Thomas
    Division of Pulmonary Critical Care and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Mass 02215, USA
    Sleep 27:229-34. 2004
    ..To define the clinical and polysomnographic features of a distinct variant of obstructive sleep-disordered breathing that is remarkably mild during rapid eye movement (REM) sleep...
  20. pmc Enhancement of sleep stability with Tai Chi exercise in chronic heart failure: preliminary findings using an ECG-based spectrogram method
    Gloria Y Yeh
    Division for Research and Education in Complementary and Integrative Medical Therapies, Harvard Medical School, Boston, MA 02215, USA
    Sleep Med 9:527-36. 2008
    ....
  21. ncbi request reprint Sleep fragmentation and arousals from sleep-time scales, associations, and implications
    Robert Joseph Thomas
    Clin Neurophysiol 117:707-11. 2006