Research Topics
| Robert J ThomasSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Arousals in sleep-disordered breathing: patterns and implicationsRobert Joseph Thomas
Sleep Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Sleep 26:1042-7. 2003..To describe the whole spectrum of electroencephalographic (EEG) transients associated with the termination and recovery of obstructed respiratory events and, thus, widen the recognized spectrum of arousal phenomena from sleep...
Fatigue in the executive cortical network demonstrated in narcoleptics using functional magnetic resonance imaging--a preliminary studyRobert J Thomas
Division of Pulmonary Critical Care and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
Sleep Med 6:399-406. 2005..To demonstrate dynamic changes in cerebral functional activation during a working memory task in a state of severe excessive daytime sleepiness...
A pilot study of sleep, cognition, and respiration under 4 weeks of intermittent nocturnal hypoxia in adult humansMatthew D Weiss
Beth Israel Deaconess Medical Center and Harvard Medical School, KB 023, Pulmonary Office, 330 Brookline Avenue, Boston, MA 02215, USA
Sleep Med 10:739-45. 2009..A pilot study to examine the effects of intermittent nocturnal hypoxia on sleep, respiration and cognition in healthy adult humans...
Probabilistic sleep architecture models in patients with and without sleep apneaMatt T Bianchi
Neurology Department, Massachusetts General Hospital, Boston, MA 02114, USA
J Sleep Res 21:330-41. 2012..Markov sleep models may prove important for quantifying sleep disruption to provide objective metrics to correlate with endpoints ranging from sleepiness to cardiovascular morbidity...
Mechanisms of arousal from sleep and their consequencesGeoffrey S Gilmartin
Beth Israel Deaconess Medical Center, Division of Pulmonary, Critical Care and Sleep Medicine, Boston, Massachusetts 02115, USA
Curr Opin Pulm Med 10:468-74. 2004....
Heritability of abnormalities in cardiopulmonary coupling in sleep apnea: use of an electrocardiogram-based techniqueLamia H Ibrahim
Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University Hospitals Case Medical Center, Cleveland, Ohio 44106 6003, USA
Sleep 33:643-6. 2010..We evaluated the familial aggregation of distinctive spectrographic biomarkers of unstable sleep, related to elevated-low frequency cardiopulmonary coupling (e-LFC), to assess their utility in genetic studies...
Classification algorithms for predicting sleepiness and sleep apnea severityNathaniel A Eiseman
Neurology Department, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
J Sleep Res 21:101-12. 2012....
Electrocardiogram-based sleep spectrogram measures of sleep stability and glucose disposal in sleep disordered breathingMelanie S Pogach
Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
Sleep 35:139-48. 2012..The method allows improved characterization of the quality of stage 2 non-rapid eye movement (NREM) sleep...
Recognition and management of complex sleep-disordered breathingGeoffrey S Gilmartin
Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02115, USA
Curr Opin Pulm Med 11:485-93. 2005..It is only with a clear understanding of the factors contributing to complex sleep-disordered breathing that implementation of truly effective clinical therapy can be achieved for this disorder, which to date is poorly controlled...
Functional imaging of working memory in obstructive sleep-disordered breathingRobert J Thomas
Division of Pulmonary Critical Care and Sleep Medicine, Department of Medicine, CC 866, Sleep Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
J Appl Physiol 98:2226-34. 2005..There may be dissociations between respiratory vs. cortical recovery and objective vs. subjective recovery. Hypofrontality may provide a plausible biological mechanism for a clinical overlap with disorders of mood and attention...
An electrocardiogram-based technique to assess cardiopulmonary coupling during sleepRobert Joseph Thomas
Sleep Unit, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
Sleep 28:1151-61. 2005..To evaluate a new automated measure of cardiopulmonary coupling during sleep using a single-lead electrocardiographic signal...
Low-concentration carbon dioxide is an effective adjunct to positive airway pressure in the treatment of refractory mixed central and obstructive sleep-disordered breathingRobert Joseph Thomas
Department of Medicine, Division of Pulmonary, Critcal Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Sleep 28:69-77. 2005..To assess the efficacy of added carbon dioxide as adjunctive therapy to positive airway pressure-refractory mixed obstructive and central sleep-disordered breathing, using a prototype device-the positive airway pressure gas modulator...
Prevalent hypertension and stroke in the Sleep Heart Health Study: association with an ECG-derived spectrographic marker of cardiopulmonary couplingRobert Joseph Thomas
Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Sleep 32:897-904. 2009..This study assesses, at a population level, the associations of this spectrographic biomarker with prevalent cardiovascular disease using the Sleep Heart Health Study (SHHS)-I dataset...
Effect of added dead space to positive airway pressure for treatment of complex sleep-disordered breathingRobert Joseph Thomas
CC-866, Sleep Unit, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
Sleep Med 6:177-8. 2005
Differentiating obstructive from central and complex sleep apnea using an automated electrocardiogram-based methodRobert Joseph Thomas
Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center Boston, MA 02215, USA
Sleep 30:1756-69. 2007..The objective of this study was to assess the utility of an electrocardiogram (ECG)-based cardiopulmonary coupling technique to distinguish obstructive from central or complex sleep apnea...
Nocturnal hypoxia exposure with simulated altitude for 14 days does not significantly alter working memory or vigilance in humansRobert Joseph Thomas
Beth Israel Deaconess Medical School and Harvard Medical School, Boston, MA 02215, USA
Sleep 30:1195-203. 2007..To assess the effect of 2 weeks of nocturnal hypoxia exposure using simulated altitude on attention and working memory in healthy adult humans...
Cyclic alternating pattern in the electroencephalogram: what is its clinical utility?Robert Joseph Thomas
Division ofPulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Sleep 30:553-5. 2007
Modafinil activates cortical and subcortical sites in the sleep-deprived stateRobert Joseph Thomas
Medicine Division of Pulmonary, Critical Care and Sleep, Beth Israel Deaconess Medical Center, Boston, 02215, USA
Sleep 29:1471-81. 2006..SUBJECT OBJECTIVES: To assess the effect of the wake-promoting drug modafinil on working memory and brain activation in the executive network, following a single night of sleep deprivation...
Obstructive sleep-disordered breathing with a dominant cyclic alternating pattern--a recognizable polysomnographic variant with practical clinical implicationsRobert J Thomas
Division of Pulmonary Critical Care and Sleep Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Mass 02215, USA
Sleep 27:229-34. 2004..To define the clinical and polysomnographic features of a distinct variant of obstructive sleep-disordered breathing that is remarkably mild during rapid eye movement (REM) sleep...
Enhancement of sleep stability with Tai Chi exercise in chronic heart failure: preliminary findings using an ECG-based spectrogram methodGloria Y Yeh
Division for Research and Education in Complementary and Integrative Medical Therapies, Harvard Medical School, Boston, MA 02215, USA
Sleep Med 9:527-36. 2008....
Sleep fragmentation and arousals from sleep-time scales, associations, and implicationsRobert Joseph Thomas
Clin Neurophysiol 117:707-11. 2006
