Claudio R Thoma

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Mechanisms of aneuploidy and its suppression by tumour suppressor proteins
    Claudio R Thoma
    Institute of Cell Biology, ETH Zurich, Switzerland
    Swiss Med Wkly 141:w13170. 2011
  2. doi request reprint Genetic deletion of the long isoform of the von Hippel-Lindau tumour suppressor gene product alters microtubule dynamics
    Ian J Frew
    Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland
    Eur J Cancer 49:2433-40. 2013
  3. doi request reprint VHL loss causes spindle misorientation and chromosome instability
    Claudio R Thoma
    Institute of Cell Biology, ETH Zurich, 8093 Zurich, Switzerland
    Nat Cell Biol 11:994-1001. 2009
  4. pmc Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability
    Claudio R Thoma
    Institute of Cell Biology, Swiss Federal Institute of Technology ETH Zurich, 8093 Zurich, Switzerland
    J Cell Biol 190:991-1003. 2010

Detail Information

Publications4

  1. doi request reprint Mechanisms of aneuploidy and its suppression by tumour suppressor proteins
    Claudio R Thoma
    Institute of Cell Biology, ETH Zurich, Switzerland
    Swiss Med Wkly 141:w13170. 2011
    ..The prospects that these findings offer for understanding the role of aneuploidy in cancer are discussed in this review...
  2. doi request reprint Genetic deletion of the long isoform of the von Hippel-Lindau tumour suppressor gene product alters microtubule dynamics
    Ian J Frew
    Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland
    Eur J Cancer 49:2433-40. 2013
    ..We conclude that the microtubule-regulating function and the HIF╬▒-regulating function of pVHL are separable activities mediated by different protein isoforms...
  3. doi request reprint VHL loss causes spindle misorientation and chromosome instability
    Claudio R Thoma
    Institute of Cell Biology, ETH Zurich, 8093 Zurich, Switzerland
    Nat Cell Biol 11:994-1001. 2009
    ....
  4. pmc Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability
    Claudio R Thoma
    Institute of Cell Biology, Swiss Federal Institute of Technology ETH Zurich, 8093 Zurich, Switzerland
    J Cell Biol 190:991-1003. 2010
    ..Thus, single cell-level analysis of pVHL MT regulatory function allows new predictions for genotype to phenotype associations that deviate from the coarser clinically defined mutant classifications...