Martin H Teicher

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Sticks, stones, and hurtful words: relative effects of various forms of childhood maltreatment
    Martin H Teicher
    Department of Psychiatry, Harvard Medical School, Boston, and the Developmental Biopsychiatry Research Program, McLean Hospital, 115 Mill St, Belmont, MA 02478, USA
    Am J Psychiatry 163:993-1000. 2006
  2. pmc Hyperactivity persists in male and female adults with ADHD and remains a highly discriminative feature of the disorder: a case-control study
    Martin H Teicher
    Developmental Biopsychiatry Research Program, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    BMC Psychiatry 12:190. 2012
  3. pmc Childhood maltreatment is associated with reduced volume in the hippocampal subfields CA3, dentate gyrus, and subiculum
    Martin H Teicher
    Developmental Biopsychiatry Research Program and Brain Imaging Center, McLean Hospital, Belmont, MA 02478, USA
    Proc Natl Acad Sci U S A 109:E563-72. 2012
  4. pmc Witnessing violence toward siblings: an understudied but potent form of early adversity
    Martin H Teicher
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    PLoS ONE 6:e28852. 2011
  5. ncbi request reprint The neurobiological consequences of early stress and childhood maltreatment
    Martin H Teicher
    Department of Psychiatry, Harvard Medical School, and Developmental Biopsychiatry Research Program, McLean Hospital, Belmont, MA 02478, USA
    Neurosci Biobehav Rev 27:33-44. 2003
  6. ncbi request reprint Novel strategy for the analysis of CPT data provides new insight into the effects of methylphenidate on attentional states in children with ADHD
    Martin H Teicher
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    J Child Adolesc Psychopharmacol 14:219-32. 2004
  7. ncbi request reprint Neurobiological consequences of early stress and childhood maltreatment: are results from human and animal studies comparable?
    Martin H Teicher
    Developmental Biopsychiatry Research Program, McLean Hospital, 115 Mill Street Belmont, MA 02478, USA
    Ann N Y Acad Sci 1071:313-23. 2006
  8. ncbi request reprint Methylphenidate blood levels and therapeutic response in children with attention-deficit hyperactivity disorder: I. Effects of different dosing regimens
    Martin H Teicher
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, Developmental Biopsychiatry Research Program, McLean Hospital, Belmont, Massachusetts, USA
    J Child Adolesc Psychopharmacol 16:416-31. 2006
  9. ncbi request reprint Rate dependency revisited: understanding the effects of methylphenidate in children with attention deficit hyperactivity disorder
    Martin H Teicher
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    J Child Adolesc Psychopharmacol 13:41-51. 2003
  10. pmc Utility of objective measures of activity and attention in the assessment of therapeutic response to stimulants in children with attention-deficit/hyperactivity disorder
    Martin H Teicher
    Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, Massachusetts, USA
    J Child Adolesc Psychopharmacol 18:265-70. 2008

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Sticks, stones, and hurtful words: relative effects of various forms of childhood maltreatment
    Martin H Teicher
    Department of Psychiatry, Harvard Medical School, Boston, and the Developmental Biopsychiatry Research Program, McLean Hospital, 115 Mill St, Belmont, MA 02478, USA
    Am J Psychiatry 163:993-1000. 2006
    ..This study was designed to delineate the impact of parental verbal aggression, witnessing domestic violence, physical abuse, and sexual abuse, by themselves and in combination, on psychiatric symptoms...
  2. pmc Hyperactivity persists in male and female adults with ADHD and remains a highly discriminative feature of the disorder: a case-control study
    Martin H Teicher
    Developmental Biopsychiatry Research Program, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    BMC Psychiatry 12:190. 2012
    ..Symptoms of hyperactivity are believed to fade with age leaving ADHD adults mostly inattentive and impulsive. Our aim was to test this assertion using objective measures of hyperactivity, impulsivity and inattention...
  3. pmc Childhood maltreatment is associated with reduced volume in the hippocampal subfields CA3, dentate gyrus, and subiculum
    Martin H Teicher
    Developmental Biopsychiatry Research Program and Brain Imaging Center, McLean Hospital, Belmont, MA 02478, USA
    Proc Natl Acad Sci U S A 109:E563-72. 2012
    ..2% and 4.3% reductions in the left presubiculum and subiculum, respectively. These findings support the hypothesis that exposure to early stress in humans, as in other animals, affects hippocampal subfield development...
  4. pmc Witnessing violence toward siblings: an understudied but potent form of early adversity
    Martin H Teicher
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    PLoS ONE 6:e28852. 2011
    ..These findings suggest that greater attention be given to the effects of witnessing aggression toward siblings in studies of domestic violence, abuse and early adversity...
  5. ncbi request reprint The neurobiological consequences of early stress and childhood maltreatment
    Martin H Teicher
    Department of Psychiatry, Harvard Medical School, and Developmental Biopsychiatry Research Program, McLean Hospital, Belmont, MA 02478, USA
    Neurosci Biobehav Rev 27:33-44. 2003
    ..There are also gender differences in vulnerability and functional consequences. The neurobiological sequelae of early stress and maltreatment may play a significant role in the emergence of psychiatric disorders during development...
  6. ncbi request reprint Novel strategy for the analysis of CPT data provides new insight into the effects of methylphenidate on attentional states in children with ADHD
    Martin H Teicher
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    J Child Adolesc Psychopharmacol 14:219-32. 2004
    ..Children with ADHD could be subtyped according to the nature of their attention performance problems, and these subtypes differed in levels of hyperactivity and degrees of response to MPH...
  7. ncbi request reprint Neurobiological consequences of early stress and childhood maltreatment: are results from human and animal studies comparable?
    Martin H Teicher
    Developmental Biopsychiatry Research Program, McLean Hospital, 115 Mill Street Belmont, MA 02478, USA
    Ann N Y Acad Sci 1071:313-23. 2006
    ..To date, preclinical studies have guided clinical investigations and will continue to provide important insight into studies on molecular mechanisms and gene-environment interactions...
  8. ncbi request reprint Methylphenidate blood levels and therapeutic response in children with attention-deficit hyperactivity disorder: I. Effects of different dosing regimens
    Martin H Teicher
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, Developmental Biopsychiatry Research Program, McLean Hospital, Belmont, Massachusetts, USA
    J Child Adolesc Psychopharmacol 16:416-31. 2006
    ....
  9. ncbi request reprint Rate dependency revisited: understanding the effects of methylphenidate in children with attention deficit hyperactivity disorder
    Martin H Teicher
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    J Child Adolesc Psychopharmacol 13:41-51. 2003
    ..These findings illustrate a clear inverse association between symptom severity and degree of therapeutic response that is crucial for our understanding of stimulant effects and effective clinical treatment of ADHD...
  10. pmc Utility of objective measures of activity and attention in the assessment of therapeutic response to stimulants in children with attention-deficit/hyperactivity disorder
    Martin H Teicher
    Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, Massachusetts, USA
    J Child Adolesc Psychopharmacol 18:265-70. 2008
    ..We assessed whether measures of motor activity and attention using the McLean Motion Attention Test (M-MAT) could identify doses associated with optimal clinical response...
  11. ncbi request reprint Length of time between onset of childhood sexual abuse and emergence of depression in a young adult sample: a retrospective clinical report
    Martin H Teicher
    Developmental Biopsychiatry Research Program, McLean Hospital, Belmont, MA 02478, USA
    J Clin Psychiatry 70:684-91. 2009
    ..Depression is the most common adult outcome of exposure to childhood sexual abuse (CSA). In this study, we retrospectively assessed the length of time from initial abuse exposure to onset of a major depressive episode...
  12. ncbi request reprint Developmental neurobiology of childhood stress and trauma
    Martin H Teicher
    Department of Psychiatry, Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA
    Psychiatr Clin North Am 25:397-426, vii-viii. 2002
    ....
  13. pmc Harsh corporal punishment is associated with increased T2 relaxation time in dopamine-rich regions
    Yi Shin Sheu
    Developmental Biopsychiatry Research Program, McLean Hospital, Belmont MA, USA
    Neuroimage 53:412-9. 2010
    ..Alteration in the paramagnetic or hemodynamic properties of dopaminergic cell body and projection regions were observed in subjects with HCP, and these findings may relate to their increased risk for drug and alcohol abuse...
  14. pmc Exposure to parental verbal abuse is associated with increased gray matter volume in superior temporal gyrus
    Akemi Tomoda
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Neuroimage 54:S280-6. 2011
    ..Other forms of childhood abuse have been found to be associated with alterations in brain structure. The aim of this study was to ascertain whether exposure to PVA was associated with discernible effects on brain morphology...
  15. ncbi request reprint Effects of methylphenidate on functional magnetic resonance relaxometry of the cerebellar vermis in boys with ADHD
    Carl M Anderson
    Department of Psychiatry, Harvard Medical School, Boston, USA
    Am J Psychiatry 159:1322-8. 2002
    ..Also, in preclinical studies, the vermis has been shown to modulate forebrain dopamine systems, to influence locomotor activity, and to contain a significant density of dopamine transporters...
  16. ncbi request reprint Cerebellar lingula size and experiential risk factors associated with high levels of alcohol and drug use in young adults
    Carl M Anderson
    The NeuroImaging Center, McLean Hospital, Belmont, MA 02478, USA
    Cerebellum 9:198-209. 2010
    ..Lingula thickness may represent a novel, experientially sensitive, phenotypic risk factor for enhanced alcohol and drug use that perhaps modulates sensitivity to these agents...
  17. ncbi request reprint Effects of childhood sexual abuse on neuropsychological and cognitive function in college women
    Carryl P Navalta
    McLean Hospital, 115 Mill St, Belmont, MA 02478, USA
    J Neuropsychiatry Clin Neurosci 18:45-53. 2006
    ..Childhood sexual abuse appears to be associated with a constellation of neuropsychological deficiencies even in a group of relatively healthy women...
  18. pmc Reduced visual cortex gray matter volume and thickness in young adults who witnessed domestic violence during childhood
    Akemi Tomoda
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 7:e52528. 2012
    ..Exposure to multiple types of maltreatment is more commonly associated with morphological alterations in corticolimbic regions. These findings fit with preclinical studies showing that visual cortex is a highly plastic structure...
  19. pmc Reduced fractional anisotropy in the visual limbic pathway of young adults witnessing domestic violence in childhood
    Jeewook Choi
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Neuroimage 59:1071-9. 2012
    ..This finding is consistent with the hypothesis that exposure to childhood maltreatment is associated with alterations in fiber pathways that convey the adverse experience to frontal, temporal or limbic regions...
  20. pmc Hurtful words: association of exposure to peer verbal abuse with elevated psychiatric symptom scores and corpus callosum abnormalities
    Martin H Teicher
    McLean Hospital, Department of Psychiatry, Harvard Medical School, Boston, MA, USA harvard edu
    Am J Psychiatry 167:1464-71. 2010
    ..In this study the authors sought to examine the symptomatic and neuroanatomic effects, in young adulthood, of exposure to peer verbal abuse during childhood...
  21. doi request reprint Preliminary evidence for sensitive periods in the effect of childhood sexual abuse on regional brain development
    Susan L Andersen
    Department of Psychiatry, Harvard Medical School, Belmont, MA 02478, USA
    J Neuropsychiatry Clin Neurosci 20:292-301. 2008
    ..Brain regions have unique windows of vulnerability to the effects of traumatic stress...
  22. doi request reprint Childhood sexual abuse is associated with reduced gray matter volume in visual cortex of young women
    Akemi Tomoda
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
    Biol Psychiatry 66:642-8. 2009
    ..Voxel-based morphometry (VBM) provided unbiased delineation of the most significantly affected brain regions...
  23. doi request reprint Unraveling the nature of hyperactivity in children with attention-deficit/hyperactivity disorder
    Kyoko Ohashi
    Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, Massachusetts 02178, USA
    Arch Gen Psychiatry 67:388-96. 2010
    ..Seated hyperactivity is a defining feature of the combined and predominantly hyperactive-impulsive subtypes of attention-deficit/hyperactivity disorder (ADHD), but its underlying nature is unknown...
  24. ncbi request reprint Scars that won't heal: the neurobiology of child abuse
    Martin H Teicher
    Developmental Biopsychiatry Research Program, McLean Hospital, Belmont, Mass, USA
    Sci Am 286:68-75. 2002
  25. pmc Reduced prefrontal cortical gray matter volume in young adults exposed to harsh corporal punishment
    Akemi Tomoda
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Neuroimage 47:T66-71. 2009
    ..The aim of this study was to investigate whether HCP was associated with discernible alterations in gray matter volume (GMV) using voxel-based morphometry (VBM)...
  26. doi request reprint Stress, sensitive periods and maturational events in adolescent depression
    Susan L Andersen
    Department of Psychiatry, McLean Hospital and Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA
    Trends Neurosci 31:183-91. 2008
    ..Adolescent depression is a serious recurrent brain-based disorder. Understanding the genesis and neurobiological basis is important in the development of more effective intervention strategies to treat or prevent the disorder...
  27. ncbi request reprint Childhood neglect is associated with reduced corpus callosum area
    Martin H Teicher
    Developmental Biopsychiatry Research Program, McLean Hospital, Belmont, Massachusetts 02478, USA
    Biol Psychiatry 56:80-5. 2004
    ..Childhood abuse has been associated with abnormalities in brain development, particularly corpus callosum (CC) morphology. The impact of neglect has not been assessed, though it is the most prevalent form of childhood maltreatment...
  28. pmc Desperately driven and no brakes: developmental stress exposure and subsequent risk for substance abuse
    Susan L Andersen
    Developmental Biopsychiatry Research Program, McLean Hospital Harvard Medical School, Belmont, MA 02478, USA
    Neurosci Biobehav Rev 33:516-24. 2009
    ..Together, these factors may explain why exposure to early adversity increases risk to abuse substances during adolescence...
  29. pmc Preliminary evidence for white matter tract abnormalities in young adults exposed to parental verbal abuse
    Jeewook Choi
    Department of Psychiatry, Harvard Medical School, Boston, Massachusetts Developmental Biopsychiatry Research Program, McLean Hospital, Belmont, Massachusetts Department of Psychiatry, Catholic University of Korea, South Korea
    Biol Psychiatry 65:227-34. 2009
    ..Diffusion tensor imaging (DTI) was used to ascertain whether PVA was associated with abnormalities in white matter (WM) tract integrity...
  30. ncbi request reprint Transient dopamine synthesis modulation in prefrontal cortex: in vitro studies
    Nathalie L Dumont
    Department of Psychiatry, Harvard Medical School, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Brain Res Dev Brain Res 150:163-6. 2004
    ..The inhibitory effects of both agonists were antagonized by pre-incubation with the D1 antagonist SCH-23390 in cortex, but not in striatum...
  31. ncbi request reprint Parental posttraumatic stress disorder as a vulnerability factor for low cortisol trait in offspring of holocaust survivors
    Rachel Yehuda
    Traumatic Stress Studies Program, Department of Psychiatry, Mount Sinai School of Medicine and James J Peters Veterans Affairs Medical Center, Bronx, NY, USA
    Arch Gen Psychiatry 64:1040-8. 2007
    ....
  32. ncbi request reprint Hand preference and spring-summer vs fall-winter seasonal affective disorder
    Charles S Mirabile
    McLean Hospital, Belmont, MA, USA
    Percept Mot Skills 95:887-8. 2002
    ..Spring-summer depression and fall-winter good spirits were more evident among 9 left-handers. The reverse pattern was observed for the 9 right-handers...
  33. ncbi request reprint Abnormal T2 relaxation time in the cerebellar vermis of adults sexually abused in childhood: potential role of the vermis in stress-enhanced risk for drug abuse
    Carl M Anderson
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Psychoneuroendocrinology 27:231-44. 2002
    ..Together these findings suggest that early trauma may interfere with the development of the vermis, and produce neuropsychiatric symptoms associated with drug use...
  34. ncbi request reprint Hand preference and length of psychiatric hospital stay by month of admission
    Charles S Mirabile
    McLean Hospital, Belmont, MA, USA
    Percept Mot Skills 95:835-6. 2002
    ..5% longer than for left-handed subjects admitted during any other period. In contrast, length of stay for right-handed patients differed by no more than 16% between any months compared...
  35. ncbi request reprint Parental verbal affection and verbal aggression in childhood differentially influence psychiatric symptoms and wellbeing in young adulthood
    Ann Polcari
    Northeastern University, Bouve College of Health Sciences, School of Nursing, 360 Huntington Avenue, Boston, MA 02115, USA Developmental Biopsychiatry Research Program, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA Department of Psychiatry, Harvard Medical School, USA
    Child Abuse Negl 38:91-102. 2014
    ..These findings also suggest that ridicule, disdain, and humiliation cannot be easily counteracted by praise and warmth from the same or another parent. ..
  36. pmc New clathrin-based nanoplatforms for magnetic resonance imaging
    GORDANA D VITALIANO
    Laboratory of Developmental Psychopharmacology, Brain Imaging Center, Department of Psychiatry, Harvard Medical School, McLean Hospital, Belmont, Massachusetts, United States of America
    PLoS ONE 7:e35821. 2012
    ..Our goal was to develop a new MRI method with the potential for non-invasive molecular brain imaging. We herein introduce new bio-nanotechnology approaches for designing CNS contrast media based on the ubiquitous clathrin cell protein...
  37. pmc Psychological benefits 2 and 4 weeks after a single treatment with near infrared light to the forehead: a pilot study of 10 patients with major depression and anxiety
    Fredric Schiffer
    The Department of Psychiatry, Harvard Medical School and the Developmental Biopsychiatry Research Program, McLean Hospital, 115 Mill Street Belmont, MA 02478 USA
    Behav Brain Funct 5:46. 2009
    ..abstract:..
  38. ncbi request reprint Delayed effects of early stress on hippocampal development
    Susan L Andersen
    Developmental Psychopharmacology Laboratory, Department of Psychiatry, Harvard Medical School, Belmont, MA, USA
    Neuropsychopharmacology 29:1988-93. 2004
    ..Overall, these results suggest that early maternal separation produced a regionally specific delayed effect on the structure of the hippocampus by attenuating rates of synaptic development...
  39. ncbi request reprint Pubertal changes in gonadal hormones do not underlie adolescent dopamine receptor overproduction
    Susan L Andersen
    Department of Psychiatry, Harvard Medical School, Laboratory of Developmental Psychopharmacology, Mailman Laboratories for Psychiatric Research, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Psychoneuroendocrinology 27:683-91. 2002
    ..The results of this study suggest that the endogenous rise in gonadal steroid hormones during puberty is not responsible for the overproduction of receptors in males or the lack of overproduction in females...
  40. ncbi request reprint Differences in behavior and monoamine laterality following neonatal clomipramine treatment
    Susan L Andersen
    Department of Psychiatry, Harvard Medical School, Laboratory of Developmental Psychopharmacology, McLean Hospital, Belmont, MA 02478, USA
    Dev Psychobiol 41:50-7. 2002
    ..This decline in monoaminergic content is consistent with clinical studies demonstrating decrements in serotonin as well as alterations in the lateralization of function in individuals with major depressive order...
  41. ncbi request reprint Sensitive periods of amygdala development: The role of maltreatment in preadolescence
    Pia Pechtel
    Center for Depression, Anxiety and Stress Research, McLean Hospital, 115 Mill Street, Belmont, MA 02478 9106, USA Department of Psychiatry, Harvard Medical School, USA Electronic address
    Neuroimage 97:236-44. 2014
    ..Severity of adversity experienced at age 10-11 contributed to larger right but not left amygdala volume in adulthood. Results provide preliminary evidence that the amygdala may have a developmental sensitive period in preadolescence. ..
  42. ncbi request reprint Hand preference, susceptibility to motion sickness, and differential vulnerability to psychiatric admission
    Charles S Mirabile
    McLean Hospital, Belmont, MA, USA
    Percept Mot Skills 95:813-4. 2002
    ..Vulnerability of nonright-handers to admission appears to be associated with an intermediate extent of susceptibility to motion sickness...
  43. ncbi request reprint Hand preference and diagnosis in major mental illness
    Charles S Mirabile
    McLean Hospital, Belmont, MA, USA
    Percept Mot Skills 95:875-6. 2002
    ....
  44. doi request reprint Prediction of clinical outcomes from rTMS in depressed patients with lateral visual field stimulation: a replication
    Fredric Schiffer
    Department of Psychiatry at Harvard Medical School, Boston, MA, USA
    J Neuropsychiatry Clin Neurosci 20:194-200. 2008
    ..These correlations, across the whole group and within genders, were almost identical to those previously reported from 37 patients studied at a different site...
  45. pmc A polymorphism in the norepinephrine transporter gene alters promoter activity and is associated with attention-deficit hyperactivity disorder
    Chun Hyung Kim
    Molecular Neurobiology, McLean Hospital, Harvard Medical School, Belmont, MA 02478, USA
    Proc Natl Acad Sci U S A 103:19164-9. 2006
    ....
  46. ncbi request reprint 24-h Monitoring of plasma norepinephrine, MHPG, cortisol, growth hormone and prolactin in depression
    Harold W Koenigsberg
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    J Psychiatr Res 38:503-11. 2004
    ..The present study takes advantage of frequent plasma sampling over the 24-h period and a multioscillator cosinor model to fit the 24-h rhythms...
  47. ncbi request reprint Objective measures of activity and attention in the differential diagnosis of psychiatric disorders of childhood
    Gianni L Faedda
    Lucio Bini Mood Disorders Center of New York, New York, NY, USA
    Essent Psychopharmacol 6:239-49. 2005
    ..Thus, objective measures of attention and activity can be of assistance in the differential diagnosis of ADHD and BD...