K G Tantisira

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Expression analysis of asthma candidate genes during human and murine lung development
    Erik Melen
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Respir Res 12:86. 2011
  2. pmc Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma
    Benjamin A Raby
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Respir Res 10:67. 2009
  3. pmc Platform dependence of inference on gene-wise and gene-set involvement in human lung development
    Rose Du
    Channing Laboratory, Brigham and Women s Hospital, Boston, MA 02115, USA
    BMC Bioinformatics 10:189. 2009
  4. pmc Childhood infections and asthma: at the crossroads of the hygiene and Barker hypotheses
    K G Tantisira
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Respir Res 2:324-7. 2001
  5. pmc Association of body mass with pulmonary function in the Childhood Asthma Management Program (CAMP)
    K G Tantisira
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Thorax 58:1036-41. 2003
  6. ncbi Toll-like receptor 6 gene (TLR6): single-nucleotide polymorphism frequencies and preliminary association with the diagnosis of asthma
    K Tantisira
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Genes Immun 5:343-6. 2004
  7. pmc Genetics and pharmacogenetics of the leukotriene pathway
    Kelan G Tantisira
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02115, USA
    J Allergy Clin Immunol 124:422-7. 2009
  8. pmc Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma
    Kelan G Tantisira
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, USA
    N Engl J Med 365:1173-83. 2011
  9. ncbi Overview of the pharmacogenetics of asthma treatment
    S T Weiss
    Channing Laboratory, Brigham and Women s Hospital, Boston, MA 02115, USA
    Pharmacogenomics J 6:311-26. 2006

Collaborators

Detail Information

Publications9

  1. pmc Expression analysis of asthma candidate genes during human and murine lung development
    Erik Melen
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Respir Res 12:86. 2011
    ..Little is known about the role of most asthma susceptibility genes during human lung development. Genetic determinants for normal lung development are not only important early in life, but also for later lung function...
  2. pmc Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma
    Benjamin A Raby
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Respir Res 10:67. 2009
    ..We hypothesize that common IPO13 genetic variation influences the anti-inflammatory effects of inhaled corticosteroids for the treatment of asthma, as measured by change in methacholine airway hyperresponsiveness (AHR-PC20)...
  3. pmc Platform dependence of inference on gene-wise and gene-set involvement in human lung development
    Rose Du
    Channing Laboratory, Brigham and Women s Hospital, Boston, MA 02115, USA
    BMC Bioinformatics 10:189. 2009
    ..0 and the Illumina HumanRef-8 v2 Expression Bead Chips, for comparability in a biological system in which changes may be subtle, namely fetal lung tissue as a function of gestational age...
  4. pmc Childhood infections and asthma: at the crossroads of the hygiene and Barker hypotheses
    K G Tantisira
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Respir Res 2:324-7. 2001
    ....
  5. pmc Association of body mass with pulmonary function in the Childhood Asthma Management Program (CAMP)
    K G Tantisira
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Thorax 58:1036-41. 2003
    ..While increases in body mass index (BMI) have been associated with the incidence and prevalence of asthma, the mechanisms behind this association are unclear...
  6. ncbi Toll-like receptor 6 gene (TLR6): single-nucleotide polymorphism frequencies and preliminary association with the diagnosis of asthma
    K Tantisira
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Genes Immun 5:343-6. 2004
    ..Although replication of this finding in other, larger samples is needed, variation in TLR6 may have relevance to the pathogenesis of immunologically mediated diseases...
  7. pmc Genetics and pharmacogenetics of the leukotriene pathway
    Kelan G Tantisira
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02115, USA
    J Allergy Clin Immunol 124:422-7. 2009
    ..Future studies aimed at providing a broader scope of investigation through increased sample sizes and through genome-wide approaches are needed...
  8. pmc Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma
    Kelan G Tantisira
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, USA
    N Engl J Med 365:1173-83. 2011
    ..We hypothesized that a genomewide association study would reveal novel pharmacogenetic determinants of the response to inhaled glucocorticoids...
  9. ncbi Overview of the pharmacogenetics of asthma treatment
    S T Weiss
    Channing Laboratory, Brigham and Women s Hospital, Boston, MA 02115, USA
    Pharmacogenomics J 6:311-26. 2006
    ..Identification of such replicable loci is the next step towards the goal of 'individualized therapy' for asthma...