Alex Y Tan

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. doi request reprint Atrial fibrillation and atrial fibrosis
    Alex Y Tan
    Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    J Cardiovasc Pharmacol 57:625-9. 2011
  2. pmc Neural mechanisms of paroxysmal atrial fibrillation and paroxysmal atrial tachycardia in ambulatory canines
    Alex Y Tan
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Circulation 118:916-25. 2008
  3. pmc Ectopic atrial arrhythmias arising from canine thoracic veins during in vivo stellate ganglia stimulation
    Alex Y Tan
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Am J Physiol Heart Circ Physiol 295:H691-8. 2008
  4. ncbi request reprint Spontaneous stellate ganglion nerve activity and ventricular arrhythmia in a canine model of sudden death
    Shengmei Zhou
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    Heart Rhythm 5:131-9. 2008
  5. ncbi request reprint The mechanisms of atrial fibrillation
    Peng Sheng Chen
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Cardiovasc Electrophysiol 17:S2-7. 2006
  6. pmc Antiarrhythmic effects of beta3-adrenergic receptor stimulation in a canine model of ventricular tachycardia
    Shengmei Zhou
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    Heart Rhythm 5:289-97. 2008
  7. ncbi request reprint Left stellate ganglion and vagal nerve activity and cardiac arrhythmias in ambulatory dogs with pacing-induced congestive heart failure
    Masahiro Ogawa
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Am Coll Cardiol 50:335-43. 2007
  8. pmc Autonomic nerves in pulmonary veins
    Alex Y Tan
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    Heart Rhythm 4:S57-60. 2007
  9. pmc Cryoablation of stellate ganglia and atrial arrhythmia in ambulatory dogs with pacing-induced heart failure
    Masahiro Ogawa
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    Heart Rhythm 6:1772-9. 2009
  10. doi request reprint Atrial sympathetic and parasympathetic nerve sprouting and hyperinnervation induced by subthreshold electrical stimulation of the left stellate ganglion in normal dogs
    Moshe Swissa
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center Los Angeles, CA 90027, USA
    Cardiovasc Pathol 17:303-8. 2008

Collaborators

Detail Information

Publications17

  1. doi request reprint Atrial fibrillation and atrial fibrosis
    Alex Y Tan
    Division of Cardiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    J Cardiovasc Pharmacol 57:625-9. 2011
    ..This article reviews the role that atrial fibrosis plays in AF, the mechanisms of atrial fibrosis, and emerging therapeutic approaches to AF aimed at attenuating atrial fibrosis...
  2. pmc Neural mechanisms of paroxysmal atrial fibrillation and paroxysmal atrial tachycardia in ambulatory canines
    Alex Y Tan
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Circulation 118:916-25. 2008
    ..The relationship between autonomic activation and the mechanisms of paroxysmal atrial fibrillation remains unclear...
  3. pmc Ectopic atrial arrhythmias arising from canine thoracic veins during in vivo stellate ganglia stimulation
    Alex Y Tan
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Am J Physiol Heart Circ Physiol 295:H691-8. 2008
    ....
  4. ncbi request reprint Spontaneous stellate ganglion nerve activity and ventricular arrhythmia in a canine model of sudden death
    Shengmei Zhou
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    Heart Rhythm 5:131-9. 2008
    ..Little information is available on the temporal relationship between instantaneous sympathetic nerve activity and ventricular arrhythmia in ambulatory animals...
  5. ncbi request reprint The mechanisms of atrial fibrillation
    Peng Sheng Chen
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
    J Cardiovasc Electrophysiol 17:S2-7. 2006
    ..Therefore, thoracic vein isolation is an important technique in AF control. We conclude that thoracic veins are important in the generation and maintenance of AF...
  6. pmc Antiarrhythmic effects of beta3-adrenergic receptor stimulation in a canine model of ventricular tachycardia
    Shengmei Zhou
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    Heart Rhythm 5:289-97. 2008
    ..Beta3-adrenergic receptor (beta3-AR) stimulation inhibits cardiac contractility...
  7. ncbi request reprint Left stellate ganglion and vagal nerve activity and cardiac arrhythmias in ambulatory dogs with pacing-induced congestive heart failure
    Masahiro Ogawa
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    J Am Coll Cardiol 50:335-43. 2007
    ..The purpose of this study was to determine the patterns of autonomic nerve activity in congestive heart failure (CHF)...
  8. pmc Autonomic nerves in pulmonary veins
    Alex Y Tan
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    Heart Rhythm 4:S57-60. 2007
    ..This review summarizes recent developments in the understanding of the anatomy of autonomic nerves in and around pulmonary veins and their implications for atrial fibrillation...
  9. pmc Cryoablation of stellate ganglia and atrial arrhythmia in ambulatory dogs with pacing-induced heart failure
    Masahiro Ogawa
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, California, USA
    Heart Rhythm 6:1772-9. 2009
    ..There is an association between autonomic nerve discharges and atrial arrhythmias (including bradycardia and tachycardia) in ambulatory dogs with pacing-induced heart failure (HF)...
  10. doi request reprint Atrial sympathetic and parasympathetic nerve sprouting and hyperinnervation induced by subthreshold electrical stimulation of the left stellate ganglion in normal dogs
    Moshe Swissa
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center Los Angeles, CA 90027, USA
    Cardiovasc Pathol 17:303-8. 2008
    ..It is unclear whether a similar neural plasticity involving both sympathetic and parasympathetic innervation also exists in the atria...
  11. pmc Autonomic nerve activity and atrial fibrillation
    Peng Sheng Chen
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center and David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA
    Heart Rhythm 4:S61-4. 2007
    ..ANS activity and Ca(i) transient dynamics are important in the development of PAF. These studies suggest that new methods or drugs aimed at modification of cardiac ANS activity may lead to new opportunities for AF control...
  12. ncbi request reprint Electrical connections between left superior pulmonary vein, left atrium, and ligament of Marshall: implications for mechanisms of atrial fibrillation
    Alex Y Tan
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
    Am J Physiol Heart Circ Physiol 290:H312-22. 2006
    ..LOM-LSPV connection forms an accessory pathway that contributes to the electrical coupling between LSPV and LA during SR and AF. This pathway may contribute to rapid activations within the LSPV during AF...
  13. ncbi request reprint Vein of Marshall activity during sustained atrial fibrillation
    Santosh Kamanu
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center and the David Geffen School of Medicine, UCLA, Los Angeles, CA, USA
    J Cardiovasc Electrophysiol 17:839-46. 2006
    ..The human vein of Marshall (VOM) activation patterns during sustained (persistent or permanent) atrial fibrillation (AF) have not been studied in detail...
  14. ncbi request reprint Intracellular calcium and vulnerability to fibrillation and defibrillation in Langendorff-perfused rabbit ventricles
    Gyo Seung Hwang
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Circulation 114:2595-603. 2006
    ..The role of intracellular calcium (Ca(i)) in defibrillation and vulnerability is unclear...
  15. ncbi request reprint Autonomic innervation and segmental muscular disconnections at the human pulmonary vein-atrial junction: implications for catheter ablation of atrial-pulmonary vein junction
    Alex Y Tan
    Division of Cardiology, Department of Medicine, Los Angeles, California, USA
    J Am Coll Cardiol 48:132-43. 2006
    ..This study sought to examine the muscle connections and autonomic nerve distributions at the human pulmonary vein (PV)-left atrium (LA) junction...
  16. ncbi request reprint Circadian variations of stellate ganglion nerve activity in ambulatory dogs
    Byung Chun Jung
    Division of Cardiology, Department of Medicine, Cedars Sinai Medical Center, CA 90048 1865, USA
    Heart Rhythm 3:78-85. 2006
    ..The presence of circadian variations in sympathetic outflow from the stellate ganglia is unclear...
  17. ncbi request reprint High-density mapping of pulmonary veins and left atrium during ibutilide administration in a canine model of sustained atrial fibrillation
    Chung Chuan Chou
    Division of Cardiology, Department of Medicine, Rm 5537, Cedars Sinai Medical Center, 8700 Beverly Blvd, Los Angeles, CA 90048, USA
    Am J Physiol Heart Circ Physiol 289:H2704-13. 2005
    ..These findings suggest that the PV FD during AF is due to nonreentrant mechanisms. High doses of ibutilide may completely terminate all reentrant activity, converting AF to PV tachycardia before the resumption of sinus rhythm...