RULLA MAY TAMIMI

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Nondense mammographic area and risk of breast cancer
    Andreas Pettersson
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Breast Cancer Res 13:R100. 2011
  2. pmc Columnar cell lesions and subsequent breast cancer risk: a nested case-control study
    Sarah A Aroner
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Breast Cancer Res 12:R61. 2010
  3. pmc Circulating carotenoids, mammographic density, and subsequent risk of breast cancer
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Res 69:9323-9. 2009
  4. pmc Circulating colony stimulating factor-1 and breast cancer risk
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Res 68:18-21. 2008
  5. pmc Breast cancer susceptibility loci and mammographic density
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA
    Breast Cancer Res 10:R66. 2008
  6. pmc Single nucleotide polymorphisms and breast cancer: not yet a success story
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Breast Cancer Res 8:108. 2006
  7. ncbi request reprint Endogenous sex hormone levels and mammographic density among postmenopausal women
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:2641-7. 2005
  8. pmc Benign breast disease, recent alcohol consumption, and risk of breast cancer: a nested case-control study
    Rulla M Tamimi
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Breast Cancer Res 7:R555-62. 2005
  9. pmc Expression of IGF1R in normal breast tissue and subsequent risk of breast cancer
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Breast Cancer Res Treat 128:243-50. 2011
  10. pmc Traditional breast cancer risk factors in relation to molecular subtypes of breast cancer
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Breast Cancer Res Treat 131:159-67. 2012

Research Grants

  1. Molecular Predictors of Mammographic Density
    Rulla M Tamimi; Fiscal Year: 2010
  2. Whole Genome Association Study of Mammographic Density
    Rulla Tamimi; Fiscal Year: 2009
  3. Molecular Predictors of Mammographic Density
    Rulla Tamimi; Fiscal Year: 2009
  4. BENIGN BREAST DISEASE AND RISK OF BREAST CANCER
    Rulla Tamimi; Fiscal Year: 2009
  5. Vitamin D and Mammographic Density
    Rulla Tamimi; Fiscal Year: 2007
  6. BENIGN BREAST DISEASE AND RISK OF BREAST CANCER
    Rulla Tamimi; Fiscal Year: 2007
  7. Whole Genome Association Study of Mammographic Density
    Rulla M Tamimi; Fiscal Year: 2010

Detail Information

Publications41

  1. pmc Nondense mammographic area and risk of breast cancer
    Andreas Pettersson
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Breast Cancer Res 13:R100. 2011
    ..We investigated separately the absolute dense area and the absolute nondense area on mammograms in relation to breast cancer risk...
  2. pmc Columnar cell lesions and subsequent breast cancer risk: a nested case-control study
    Sarah A Aroner
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Breast Cancer Res 12:R61. 2010
    ..However, the risk of subsequent breast cancer associated with the presence of CCL in a benign breast biopsy is poorly understood...
  3. pmc Circulating carotenoids, mammographic density, and subsequent risk of breast cancer
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Res 69:9323-9. 2009
    ..05). Our results suggest that plasma levels of carotenoids may play a role in reducing breast cancer risk, particularly among women with high mammographic density...
  4. pmc Circulating colony stimulating factor-1 and breast cancer risk
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Res 68:18-21. 2008
    ..45; 95% CI, 1.02-2.07; P(trend) = 0.06) and ER+/PR+ tumors (RR, 1.72; 95% CI, 1.11-2.66; P(trend) = 0.04). Thus, the association of circulating CSF1 levels and breast cancer varies by menopausal status...
  5. pmc Breast cancer susceptibility loci and mammographic density
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA
    Breast Cancer Res 10:R66. 2008
    ....
  6. pmc Single nucleotide polymorphisms and breast cancer: not yet a success story
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Breast Cancer Res 8:108. 2006
    ..Future studies should perhaps also consider alternative designs such as using surrogate (preferably continuous) markers of breast cancer, focusing on high-risk populations, and defining pathologically distinct outcomes...
  7. ncbi request reprint Endogenous sex hormone levels and mammographic density among postmenopausal women
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:2641-7. 2005
    ..The mechanism by which breast density increases breast cancer risk is unclear although it has been hypothesized that breast density reflects cumulative exposure to estrogens...
  8. pmc Benign breast disease, recent alcohol consumption, and risk of breast cancer: a nested case-control study
    Rulla M Tamimi
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Breast Cancer Res 7:R555-62. 2005
    ....
  9. pmc Expression of IGF1R in normal breast tissue and subsequent risk of breast cancer
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Breast Cancer Res Treat 128:243-50. 2011
    ..Further studies to confirm these findings are necessary...
  10. pmc Traditional breast cancer risk factors in relation to molecular subtypes of breast cancer
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Breast Cancer Res Treat 131:159-67. 2012
    ..Identifying risk factors for less common subtypes such as luminal B, HER2-type and basal-like tumors has important implications for prevention of these more aggressive subtypes...
  11. pmc Comparison of molecular phenotypes of ductal carcinoma in situ and invasive breast cancer
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA, 02115, USA
    Breast Cancer Res 10:R67. 2008
    ..The purpose of this study was to compare the prevalence of these distinct molecular subtypes among cases of DCIS and invasive breast cancer...
  12. ncbi request reprint Endogenous hormone levels, mammographic density, and subsequent risk of breast cancer in postmenopausal women
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 99:1178-87. 2007
    ..Whether mammographic density reflects levels of endogenous sex hormones is unclear. We examined whether these predictors are independently associated with breast cancer risk in a prospective study...
  13. ncbi request reprint The HRAS1 variable number of tandem repeats and risk of breast cancer
    Rulla M Tamimi
    Department of Epidemiology, Harvard School of Public Health, and Channing Laboratory, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 12:1528-30. 2003
    ..These results suggest that there is no overall association between rare alleles of the HRAS1 VNTR and breast cancer...
  14. ncbi request reprint Manganese superoxide dismutase polymorphism, plasma antioxidants, cigarette smoking, and risk of breast cancer
    Rulla M Tamimi
    Department ofEpidemiology, Harvard School of Public Health, Boston, MA, USA
    Cancer Epidemiol Biomarkers Prev 13:989-96. 2004
    ..41; 95% confidence interval 0.77-2.60; P for interaction = 0.03). These data suggest that the Ala allele of MnSOD may modify breast cancer risk among current smokers, but is not an independent risk factor for breast cancer...
  15. pmc Evaluation of a breast cancer risk prediction model expanded to include category of prior benign breast disease lesion
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 116:4944-53. 2010
    ..Given the substantial heterogeneity in breast cancer risk dependent on the type of benign lesion, the authors evaluated whether incorporating this level of detail would improve the discriminatory power of risk classification models...
  16. ncbi request reprint Plasma carotenoids, retinol, and tocopherols and risk of breast cancer
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, 181 Longwood Avenue, Boston, MA 02115, USA
    Am J Epidemiol 161:153-60. 2005
    ..Although the association was strongest for alpha-carotene, the high degree of collinearity among plasma carotenoids limits our ability to conclude that this association is specific to any individual carotenoid...
  17. pmc Genetic variation and circulating levels of IGF-I and IGFBP-3 in relation to risk of proliferative benign breast disease
    Xuefen Su
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 126:180-90. 2010
    ..These results suggest that genetic variants and circulating levels of IGFBP-3 may play a role in the early stage of breast carcinogenesis...
  18. pmc Estrogen receptor-beta expression in invasive breast cancer in relation to molecular phenotype: results from the Nurses' Health Study
    Jonathan D Marotti
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    Mod Pathol 23:197-204. 2010
    ..The role of ER-beta in the development and progression of breast cancers defined by lack of expression of ER-alpha merits further investigation...
  19. ncbi request reprint Measures of energy balance and mammographic density in the Nurses' Health Study
    Goli Samimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Breast Cancer Res Treat 109:113-22. 2008
    ..There was no association between recent physical activity and mammographic density. These findings indicate that childhood and adult body fatness and weight change from age 18 are inversely associated with mammographic density...
  20. doi request reprint Birth weight, breast cancer susceptibility loci, and breast cancer risk
    Rulla M Tamimi
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Cancer Causes Control 21:689-96. 2010
    ....
  21. pmc Lobule type and subsequent breast cancer risk: results from the Nurses' Health Studies
    Heather J Baer
    Division of General Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
    Cancer 115:1404-11. 2009
    ..Lobules in normal breast tissue can be classified based on their degree of development, which may affect their susceptibility to carcinogenesis. However, few epidemiologic studies to date have addressed this...
  22. pmc Mammographic density, plasma vitamin D levels and risk of breast cancer in postmenopausal women
    Angela K Green
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 127:667-74. 2010
    ..Further research examining vitamin D, mammographic density and breast cancer risk is warranted...
  23. pmc Prospective study of growth and development in older girls and risk of benign breast disease in young women
    Catherine S Berkey
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 117:1612-20. 2011
    ..The authors prospectively evaluated these childhood/adolescent characteristics and BBD risk...
  24. pmc Genome-wide association scans for secondary traits using case-control samples
    Genevieve M Monsees
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Genet Epidemiol 33:717-28. 2009
    ....
  25. pmc Prospective study of adolescent alcohol consumption and risk of benign breast disease in young women
    Catherine S Berkey
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Pediatrics 125:e1081-7. 2010
    ..To investigate prospectively, using alcoholic beverage consumption data collected in real time, the association between adolescent drinking and risk of biopsy-confirmed benign breast disease (BBD) in young women...
  26. pmc Potential role of tissue microarrays for the study of biomarker expression in benign breast disease and normal breast tissue
    Laura C Collins
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Appl Immunohistochem Mol Morphol 17:438-41. 2009
    ..Whether or not TMAs may also be a potentially useful platform for assessing biomarkers in benign proliferative breast lesions (BPBL) and normal breast tissue has not been previously studied in detail...
  27. pmc Insulin-like growth factor-1- and interleukin-6-related gene variation and risk of multiple myeloma
    Brenda M Birmann
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 18:282-8. 2009
    ..Nonetheless, the data are consistent with the hypothesis that IGF-1- and IL-6-related gene variation influences susceptibility to multiple myeloma and warrant confirmation in larger populations...
  28. ncbi request reprint A prospective study of XRCC1 haplotypes and their interaction with plasma carotenoids on breast cancer risk
    Jiali Han
    Department of Nutrition, Harvard Center for Cancer Prevention, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Cancer Res 63:8536-41. 2003
    ....
  29. ncbi request reprint Outcome of patients with ductal carcinoma in situ untreated after diagnostic biopsy: results from the Nurses' Health Study
    Laura C Collins
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Cancer 103:1778-84. 2005
    ..Studies of patients with ductal carcinoma in situ (DCIS) "treated" by diagnostic biopsy alone have been rare, but provide important opportunities to gain insights into the natural history of these lesions...
  30. ncbi request reprint The influence of family history on breast cancer risk in women with biopsy-confirmed benign breast disease: results from the Nurses' Health Study
    Laura C Collins
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Cancer 107:1240-7. 2006
    ..However, the influence of a positive family history (FH) on breast cancer risk among women with biopsy-confirmed BBD is less certain...
  31. pmc Common ataxia telangiectasia mutated haplotypes and risk of breast cancer: a nested case-control study
    Rulla M Tamimi
    Program in Molecular and Genetic Epidemiology, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Breast Cancer Res 6:R416-22. 2004
    ..Five biallelic haplotype tagging single nucleotide polymorphisms are estimated to capture 99% of the haplotype diversity in Caucasian populations...
  32. pmc Gene x Gene interaction between MnSOD and GPX-1 and breast cancer risk: a nested case-control study
    David G Cox
    Program in Molecular and Genetic Epidemiology, Epidemiology Department, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    BMC Cancer 6:217. 2006
    ..We investigated whether variants at both polymorphisms, while not independently associated with breast cancer risk, could influence breast cancer risk when considered together...
  33. ncbi request reprint Magnitude and laterality of breast cancer risk according to histologic type of atypical hyperplasia: results from the Nurses' Health Study
    Laura C Collins
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Cancer 109:180-7. 2007
    ..Atypical hyperplasia (AH) in a benign breast biopsy is associated with an increased breast cancer risk. However, the influence of the histologic type of AH on the magnitude and laterality of breast cancer risk is poorly defined...
  34. pmc Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study
    Rulla M Tamimi
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Breast Cancer Res 9:R18. 2007
    ....
  35. doi request reprint Comparison of estrogen receptor results from pathology reports with results from central laboratory testing
    Laura C Collins
    Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    J Natl Cancer Inst 100:218-21. 2008
    ..78, P < .001). Thus, ER assay results from pathology reports appear to be a reasonable alternative to central laboratory ER testing for large, population-based studies of patients with breast cancer...
  36. pmc A prospective study of genetic polymorphism in MPO, antioxidant status, and breast cancer risk
    Chunyan He
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Breast Cancer Res Treat 113:585-94. 2009
    ..Further research is needed to confirm these possible associations...
  37. ncbi request reprint Combined estrogen and testosterone use and risk of breast cancer in postmenopausal women
    Rulla M Tamimi
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Arch Intern Med 166:1483-9. 2006
    ..Given the increasing trend in the use of hormone therapies containing androgens, we evaluated the relation between the use of estrogen and testosterone therapies and breast cancer...
  38. doi request reprint Birth weight and mammographic density among postmenopausal women in Sweden
    Rulla M Tamimi
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Int J Cancer 126:985-91. 2010
    ..These results indicate that adult breast density, a powerful predictor of breast cancer risk, has intrauterine roots, as reflected in birth size...
  39. pmc Intake of fiber and nuts during adolescence and incidence of proliferative benign breast disease
    Xuefen Su
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, 3rd Floor, Boston, MA 02115, USA
    Cancer Causes Control 21:1033-46. 2010
    ..We examined the association between adolescent fiber intake and proliferative BBD, a marker of increased breast cancer risk, in the Nurses' Health Study II...
  40. ncbi request reprint Pregnancy estriol, estradiol, progesterone and prolactin in relation to birth weight and other birth size variables (United States)
    Lorelei A Mucci
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Causes Control 14:311-8. 2003
    ....
  41. pmc Average energy intake among pregnant women carrying a boy compared with a girl
    Rulla M Tamimi
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    BMJ 326:1245-6. 2003

Research Grants10

  1. Molecular Predictors of Mammographic Density
    Rulla M Tamimi; Fiscal Year: 2010
    ..This is an efficient study design to determine the association between hormonal biomarkers and mammographic density and the effects of both on breast cancer risk. ..
  2. Whole Genome Association Study of Mammographic Density
    Rulla Tamimi; Fiscal Year: 2009
    ....
  3. Molecular Predictors of Mammographic Density
    Rulla Tamimi; Fiscal Year: 2009
    ..Understanding the relation between the two and how they influence breast cancer risk will be useful in risk prediction and may help to identify women at particularly high risk of breast cancer. ..
  4. BENIGN BREAST DISEASE AND RISK OF BREAST CANCER
    Rulla Tamimi; Fiscal Year: 2009
    ..The creation of tissue microarrays using benign breast tissue will lay the foundation for this and future studies to efficiently examine the role of molecular markers in the development of breast cancer. ..
  5. Vitamin D and Mammographic Density
    Rulla Tamimi; Fiscal Year: 2007
    ..Given that vitamin D levels are readily modifiable and that mammographic density is a noninvasive intermediate marker of breast cancer this proposal has important implications for breast cancer prevention. ..
  6. BENIGN BREAST DISEASE AND RISK OF BREAST CANCER
    Rulla Tamimi; Fiscal Year: 2007
    ..The creation of tissue microarrays using benign breast tissue will lay the foundation for this and future studies to efficiently examine the role of molecular markers in the development of breast cancer. ..
  7. Whole Genome Association Study of Mammographic Density
    Rulla M Tamimi; Fiscal Year: 2010
    ....