Susanne E Swalley

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Screening factors effecting a response in soluble protein expression: formalized approach using design of experiments
    Susanne E Swalley
    Vertex Pharmaceuticals Inc, 130 Waverly Street, Cambridge, MA 02139 4242, USA
    Anal Biochem 351:122-7. 2006
  2. ncbi request reprint Full-length influenza hemagglutinin HA2 refolds into the trimeric low-pH-induced conformation
    Susanne E Swalley
    Department of Biological Chemistry and Molecular Pharmacology, Howard Hughes Medical Institute, Harvard Medical School, 250 Longwood Avenue, Boston, Massachusetts 02115, USA
    Biochemistry 43:5902-11. 2004
  3. ncbi request reprint Development of a protease production platform for structure-based drug design
    Ted Fox
    Vertex Pharmaceuticals Inc, Cambridge, MA 02139, USA
    Curr Protein Pept Sci 8:439-45. 2007

Collaborators

Detail Information

Publications3

  1. ncbi request reprint Screening factors effecting a response in soluble protein expression: formalized approach using design of experiments
    Susanne E Swalley
    Vertex Pharmaceuticals Inc, 130 Waverly Street, Cambridge, MA 02139 4242, USA
    Anal Biochem 351:122-7. 2006
    ..We propose that this technique has universal application in the production of recombinant proteins, providing a powerful tool for the optimization of protein expression...
  2. ncbi request reprint Full-length influenza hemagglutinin HA2 refolds into the trimeric low-pH-induced conformation
    Susanne E Swalley
    Department of Biological Chemistry and Molecular Pharmacology, Howard Hughes Medical Institute, Harvard Medical School, 250 Longwood Avenue, Boston, Massachusetts 02115, USA
    Biochemistry 43:5902-11. 2004
    ..The refolded chimeric protein described here is a suitable species for undertaking studies of how the fusion peptide inserts into membranes and assessing the nature of possible intermediates in the fusion process...
  3. ncbi request reprint Development of a protease production platform for structure-based drug design
    Ted Fox
    Vertex Pharmaceuticals Inc, Cambridge, MA 02139, USA
    Curr Protein Pept Sci 8:439-45. 2007
    ..We have drawn on examples from our own research programs to illustrate how these strategies have been successfully used in the production of proteases for SBDD...