Steven Stufflebeam

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Clinical magnetoencephalography for neurosurgery
    Steven M Stufflebeam
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neurosurg Clin N Am 22:153-67, vii-viii. 2011
  2. pmc Localization of focal epileptic discharges using functional connectivity magnetic resonance imaging
    Steven M Stufflebeam
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    J Neurosurg 114:1693-7. 2011
  3. pmc Mapping cognitive function
    Steven M Stufflebeam
    Harvard Medical School, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Building 149, 13th Street, Charlestown, MA 02129, USA
    Neuroimaging Clin N Am 17:469-84, viii-ix. 2007
  4. pmc Onset timing of cross-sensory activations and multisensory interactions in auditory and visual sensory cortices
    Tommi Raij
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Bldg 149, 13 St, Charlestown, MA, USA
    Eur J Neurosci 31:1772-82. 2010
  5. doi request reprint Clinical applications of magnetoencephalography
    Steven M Stufflebeam
    Department of Radiology, Athinoula A Martinos Center for Biomedical Imaging, Harvard Medical School, Massachusetts General Hospital, 149 Thirteenth Street, Charlestown, MA 02129, USA
    Hum Brain Mapp 30:1813-23. 2009
  6. pmc Primary and multisensory cortical activity is correlated with audiovisual percepts
    Margo McKenna Benoit
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02114, USA
    Hum Brain Mapp 31:526-38. 2010
  7. pmc Human posterior auditory cortex gates novel sounds to consciousness
    Iiro P Jaaskelainen
    Massachusetts General Hospital, Massachusetts Institute of Technology, Harvard Medical School, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 101:6809-14. 2004
  8. pmc Quantitative analysis and biophysically realistic neural modeling of the MEG mu rhythm: rhythmogenesis and modulation of sensory-evoked responses
    Stephanie R Jones
    Massachusetts General Hospital, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
    J Neurophysiol 102:3554-72. 2009
  9. pmc Patterns of spontaneous magnetoencephalographic activity in patients with schizophrenia
    Peter J Siekmeier
    Harvard Medical School and McLean Hospital, Belmont, Massachusetts 02478, USA
    J Clin Neurophysiol 27:179-90. 2010
  10. pmc Magnetoencephalographic analysis in patients with vagus nerve stimulator
    Naoaki Tanaka
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Pediatr Neurol 41:383-7. 2009

Research Grants

  1. Superior Temporal Gyrus function in Schizophrenia
    Steven Stufflebeam; Fiscal Year: 2007

Detail Information

Publications27

  1. pmc Clinical magnetoencephalography for neurosurgery
    Steven M Stufflebeam
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neurosurg Clin N Am 22:153-67, vii-viii. 2011
    ..This article reviews the history of clinical MEG, introduces the basic concepts about the biophysics of MEG, and outlines the basic neurosurgical applications of MEG...
  2. pmc Localization of focal epileptic discharges using functional connectivity magnetic resonance imaging
    Steven M Stufflebeam
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    J Neurosurg 114:1693-7. 2011
    ..The object of this study was to investigate whether the degree of coupling of spontaneous brain activity as measured with functional connectivity MR imaging (fcMR imaging) can accurately identify and localize epileptic discharges...
  3. pmc Mapping cognitive function
    Steven M Stufflebeam
    Harvard Medical School, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Building 149, 13th Street, Charlestown, MA 02129, USA
    Neuroimaging Clin N Am 17:469-84, viii-ix. 2007
    ..A unifying theme of this article is the concept that a more complete understanding of cognition only comes through integration of multimodal structural and functional imaging technologies...
  4. pmc Onset timing of cross-sensory activations and multisensory interactions in auditory and visual sensory cortices
    Tommi Raij
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Bldg 149, 13 St, Charlestown, MA, USA
    Eur J Neurosci 31:1772-82. 2010
    ..Audiovisual interactions started at 85 ms in the left auditory, 80 ms in the right auditory and 74 ms in the visual cortex, i.e., 3-21 ms after inputs from the two modalities converged...
  5. doi request reprint Clinical applications of magnetoencephalography
    Steven M Stufflebeam
    Department of Radiology, Athinoula A Martinos Center for Biomedical Imaging, Harvard Medical School, Massachusetts General Hospital, 149 Thirteenth Street, Charlestown, MA 02129, USA
    Hum Brain Mapp 30:1813-23. 2009
    ..We also describe the most common clinical MEG applications that affect the management of patients, and discuss some applications that are close to having a clinical impact on patients...
  6. pmc Primary and multisensory cortical activity is correlated with audiovisual percepts
    Margo McKenna Benoit
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02114, USA
    Hum Brain Mapp 31:526-38. 2010
    ....
  7. pmc Human posterior auditory cortex gates novel sounds to consciousness
    Iiro P Jaaskelainen
    Massachusetts General Hospital, Massachusetts Institute of Technology, Harvard Medical School, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 101:6809-14. 2004
    ..Our converging findings suggest that transient adaptation of feature-specific neurons within human posterior auditory cortex filters superfluous sounds from entering one's awareness...
  8. pmc Quantitative analysis and biophysically realistic neural modeling of the MEG mu rhythm: rhythmogenesis and modulation of sensory-evoked responses
    Stephanie R Jones
    Massachusetts General Hospital, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
    J Neurophysiol 102:3554-72. 2009
    ..These data provide new information on the dynamics of the mu rhythm in humans and the model provides a novel mechanistic interpretation of this rhythm and its functional significance...
  9. pmc Patterns of spontaneous magnetoencephalographic activity in patients with schizophrenia
    Peter J Siekmeier
    Harvard Medical School and McLean Hospital, Belmont, Massachusetts 02478, USA
    J Clin Neurophysiol 27:179-90. 2010
    ....
  10. pmc Magnetoencephalographic analysis in patients with vagus nerve stimulator
    Naoaki Tanaka
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Pediatr Neurol 41:383-7. 2009
    ..These findings supported the diagnosis of symptomatic generalized epilepsy in this patient. Magnetoencephalography may thus be a useful option for evaluating patients with intractable epilepsy who have a vagus nerve stimulator...
  11. ncbi request reprint Application of magnetoencephalography in epilepsy patients with widespread spike or slow-wave activity
    Hideaki Shiraishi
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital Harvard Medical School, Charlestown, Massachusetts, USA
    Epilepsia 46:1264-72. 2005
    ....
  12. pmc Functional MRI using regularized parallel imaging acquisition
    Fa Hsuan Lin
    Massachusetts General Hospital, Department of Radiology, MGH HMS MIT, Athinoula A Martinos Center for Biomedical Imaging, Charlestown, Massachusetts 02129, USA
    Magn Reson Med 54:343-53. 2005
    ..Human motor and visual fMRI data acquired at different field strengths and array coils also demonstrate that regularized SENSE improves the detection of functionally active brain regions...
  13. pmc Dynamic statistical parametric mapping for analyzing ictal magnetoencephalographic spikes in patients with intractable frontal lobe epilepsy
    Naoaki Tanaka
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Epilepsy Res 85:279-86. 2009
    ..Analyzing ictal MEG spikes by using dSPMs may provide useful information in presurgical evaluation of epilepsy...
  14. ncbi request reprint Dynamic statistical parametric mapping for analyzing the magnetoencephalographic epileptiform activity in patients with epilepsy
    Hideaki Shiraishi
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital Harvard Medical School, Charlestown, MA, USA
    J Child Neurol 20:363-9. 2005
    ....
  15. pmc Task-free presurgical mapping using functional magnetic resonance imaging intrinsic activity
    Hesheng Liu
    Massachusetts General Hospital Massachusetts Institute of Technology Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, Charlestown, Massachusetts 02129, USA
    J Neurosurg 111:746-54. 2009
    ..The ability to use such methods in individual patients may provide a powerful tool for presurgical planning. The authors explore the feasibility of presurgical motor function mapping in which a task-free paradigm is used...
  16. pmc Spectral spatiotemporal imaging of cortical oscillations and interactions in the human brain
    Fa Hsuan Lin
    MGH MIT MHS Athinoula A Martinos Center for Biomedical Imaging, 13th Street, Charlestown, MA 02129, USA
    Neuroimage 23:582-95. 2004
    ..Spectral spatiotemporal imaging of cortical oscillations and interactions in the human brain can provide further understanding of large-scale neural activity and communication between different brain regions...
  17. pmc Mapping the signal-to-noise-ratios of cortical sources in magnetoencephalography and electroencephalography
    Daniel M Goldenholz
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, USA
    Hum Brain Mapp 30:1077-86. 2009
    ..Clinically, SNR maps in a patient explained differential sensitivity of MEG and EEG in detecting epileptic activity. Our results emphasize the benefits of recording MEG and EEG simultaneously...
  18. ncbi request reprint Assessing and improving the spatial accuracy in MEG source localization by depth-weighted minimum-norm estimates
    Fa Hsuan Lin
    MGH MIT HMS Athinoula A Martinos Center for Biomedical Imaging, Building 149 13th St Charlestown, MA 02129, USA
    Neuroimage 31:160-71. 2006
    ..The application of depth weighting to auditory and somatosensory experimental data illustrated the beneficial effect of depth weighting on the accuracy of spatiotemporal mapping of neuronal sources...
  19. pmc Neural correlates of tactile detection: a combined magnetoencephalography and biophysically based computational modeling study
    Stephanie R Jones
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
    J Neurosci 27:10751-64. 2007
    ..Furthermore, our model provides a biophysically realistic solution to the MEG signal and can predict the electrophysiological correlates of human perception...
  20. pmc Propagation of epileptic spikes reconstructed from spatiotemporal magnetoencephalographic and electroencephalographic source analysis
    Naoaki Tanaka
    Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuroimage 50:217-22. 2010
    ..Spatiotemporal source analysis may be useful for planning epilepsy surgery, by predicting the pattern of IEEG spikes...
  21. pmc Current dipole orientation and distribution of epileptiform activity correlates with cortical thinning in left mesiotemporal epilepsy
    Claus Reinsberger
    Department of Radiology, Athinoula A Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuroimage 52:1238-42. 2010
    ..This finding may, in part, explain the unfavorable outcome in some MTLE patients after epilepsy surgery...
  22. pmc A surface-based analysis of language lateralization and cortical asymmetry
    Douglas N Greve
    The Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Room 2301, 149 13th Street, Charlestown, MA 02129, USA
    J Cogn Neurosci 25:1477-92. 2013
    ..Overall, there were surprisingly few differences in GM volume asymmetry between LLD and RLD indicating that gross morphometric asymmetry is only subtly related to functional language laterality. ..
  23. ncbi request reprint Aids to telemetry in the presurgical evaluation of epilepsy patients: MRI, MEG and other non-invasive imaging techniques
    Susanne Knake
    Athinoula A Martinos Center for Biomedical Imaging, Charlestown, MA 02129, USA
    Suppl Clin Neurophysiol 57:494-502. 2004
  24. pmc Aberrant frontoparietal function during recognition memory in schizophrenia: a multimodal neuroimaging investigation
    Anthony P Weiss
    Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    J Neurosci 29:11347-59. 2009
    ..Inefficient utilization of prefrontal-parietal networks, with compensatory activation in temporal regions, may thus contribute to deficient old-new item recognition in schizophrenia...
  25. ncbi request reprint MRI-constrained spectral imaging of benzodiazepine modulation of spontaneous neuromagnetic activity in human cortex
    Jyrki Ahveninen
    Massachusetts General Hospital Massachusetts Institute of Technology Harvard Medical School Athinoula A Martinos Center for Biomedical Imaging, CNY149 13th Street, Charlestown, MA 02129, USA
    Neuroimage 35:577-82. 2007
    ..Anatomically constrained spectral imaging displays the cortical loci of drug effects on oscillatory brain activity, providing a novel tool for human pharmacological neuroimaging...
  26. pmc Evidence from intrinsic activity that asymmetry of the human brain is controlled by multiple factors
    Hesheng Liu
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 106:20499-503. 2009
    ..These findings show the feasibility of measuring brain asymmetry using intrinsic activity fluctuations and suggest that multiple genetic or environmental mechanisms control cerebral lateralization...
  27. pmc A non-invasive method to relate the timing of neural activity to white matter microstructural integrity
    Steven M Stufflebeam
    Department of Radiology at the Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA
    Neuroimage 42:710-6. 2008
    ..This preliminary report demonstrates a non-invasive, unbiased method to relate the timing information from evoked-response experiments to the biophysical properties of white matter measured with DTI...

Research Grants2

  1. Superior Temporal Gyrus function in Schizophrenia
    Steven Stufflebeam; Fiscal Year: 2007
    ..The hypothesis is formulated that multiple deficits in the auditory system are responsible for altered auditory processing in schizophrenia, which are measurable with functional neuroimaging. ..