Barbara E Stranger
Affiliation: Harvard University
- Progress and promise of genome-wide association studies for human complex trait geneticsBarbara E Stranger
Division of Genetics, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
Genetics 187:367-83. 2011..This review focuses primarily on the ways in which genome-wide association studies (GWASs) have revolutionized the field of human quantitative genetics...
- Coordinating GWAS results with gene expression in a systems immunologic paradigm in autoimmunityBarbara E Stranger
Division of Genetics, Brigham and Women s Hospital, Boston, MA 02115, USA
Curr Opin Immunol 24:544-51. 2012....
- Common risk alleles for inflammatory diseases are targets of recent positive selectionTowfique Raj
Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women s Hospital, Boston, MA 02115, USA Division of Genetics, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA Harvard Medical School, Boston, MA 02115, USA Program in Medical and Population Genetics, The Broad Institute, Cambridge, MA 02139, USA
Am J Hum Genet 92:517-29. 2013....
- Genome-Wide Association Study and Gene Expression Analysis Identifies CD84 as a Predictor of Response to Etanercept Therapy in Rheumatoid ArthritisJing Cui
Division of Rheumatology, Immunology, and Allergy, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
PLoS Genet 9:e1003394. 2013..These findings support a model in which CD84 genotypes and/or expression may serve as a useful biomarker for response to etanercept treatment in RA patients of European ancestry...
- Alzheimer disease susceptibility loci: evidence for a protein network under natural selectionTowfique Raj
Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences Department of Neurology, Brigham and Women s Hospital, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
Am J Hum Genet 90:720-6. 2012..The context for selection is probably unrelated to AD itself; it is likely that these genes interact in another context, such as in immune cells, where we observe cis-regulatory effects at several of the selected AD loci...