Eric J Stewart
Affiliation: Harvard University
- Aging and death in an organism that reproduces by morphologically symmetric divisionEric J Stewart
INSERM, U571, Paris, France
PLoS Biol 3:e45. 2005..These results suggest that no life strategy is immune to the effects of aging, and therefore immortality may be either too costly or mechanistically impossible in natural organisms...
- Mutations in two global regulators lower individual mortality in Escherichia coliFanette Fontaine
INSERM, U571, Paris, F 75015, France
Mol Microbiol 67:2-14. 2008..The identification of these two mutants implies that reducing mortality is not impossible; rather, due to its cost, it is subject to trade-offs with other traits that contribute to the competitive success of the organism...
- Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenationAriel B Lindner
Institut National de la Sante et de la Recherche Medicale, Unité 571, F 75015 Paris, France
Proc Natl Acad Sci U S A 105:3076-81. 2008..This suggests an asymmetric strategy whereby dividing cells segregate damage at the expense of aging individuals, resulting in the perpetuation of the population...
- Direct visualization of horizontal gene transferAna Babic
INSERM U571, Paris F 75015, France
Science 319:1533-6. 2008..The incidence of DNA splitting corresponds to about one crossover per cell generation...