R S Stern

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Oral psoralen and ultraviolet-A light (PUVA) treatment of psoriasis and persistent risk of nonmelanoma skin cancer. PUVA Follow-up Study
    R S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    J Natl Cancer Inst 90:1278-84. 1998
  2. doi request reprint The risk of squamous cell and basal cell cancer associated with psoralen and ultraviolet A therapy: a 30-year prospective study
    Robert S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Am Acad Dermatol 66:553-62. 2012
  3. doi request reprint Cost effectiveness of Mohs micrographic surgery
    Robert S Stern
    Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Invest Dermatol 133:1129-31. 2013
  4. ncbi request reprint Psoralen and ultraviolet a light therapy for psoriasis
    Robert S Stern
    Department of Dermatology, Harvard Medical School, and Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    N Engl J Med 357:682-90. 2007
  5. ncbi request reprint Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction
    Robert S Stern
    Beth Israel Deaconess Medical Center, Department of Dermatology, Harvard Medical School, Department of Dermatology, Boston, Massachusetts, USA
    J Investig Dermatol Symp Proc 9:136-9. 2004
  6. ncbi request reprint Members of the national psoriasis foundation: more extensive disease and better informed about treatment options
    Tamar Nijsten
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Arch Dermatol 141:19-26. 2005
  7. ncbi request reprint Dermatologists and office-based care of dermatologic disease in the 21st century
    Robert S Stern
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    J Investig Dermatol Symp Proc 9:126-30. 2004
  8. ncbi request reprint Chronic medication use and inflammatory skin diseases: the power and limitations of the case-control study
    Robert S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Invest Dermatol 127:2709-10. 2007
  9. doi request reprint Prevalence of a history of skin cancer in 2007: results of an incidence-based model
    Robert S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
    Arch Dermatol 146:279-82. 2010
  10. doi request reprint Psoriasis is not a useful independent risk factor for cardiovascular disease
    Robert S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Invest Dermatol 130:917-9. 2010

Collaborators

Detail Information

Publications53

  1. ncbi request reprint Oral psoralen and ultraviolet-A light (PUVA) treatment of psoriasis and persistent risk of nonmelanoma skin cancer. PUVA Follow-up Study
    R S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    J Natl Cancer Inst 90:1278-84. 1998
    ....
  2. doi request reprint The risk of squamous cell and basal cell cancer associated with psoralen and ultraviolet A therapy: a 30-year prospective study
    Robert S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Am Acad Dermatol 66:553-62. 2012
    ..Because of concerns about potential long-term adverse effects, particularly cancer, the PUVA Follow-Up Study was established to assess long-term risk and benefits of PUVA...
  3. doi request reprint Cost effectiveness of Mohs micrographic surgery
    Robert S Stern
    Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Invest Dermatol 133:1129-31. 2013
    ....
  4. ncbi request reprint Psoralen and ultraviolet a light therapy for psoriasis
    Robert S Stern
    Department of Dermatology, Harvard Medical School, and Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    N Engl J Med 357:682-90. 2007
  5. ncbi request reprint Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction
    Robert S Stern
    Beth Israel Deaconess Medical Center, Department of Dermatology, Harvard Medical School, Department of Dermatology, Boston, Massachusetts, USA
    J Investig Dermatol Symp Proc 9:136-9. 2004
    ..Many individuals with little psoriasis at the time of interview considered the disease to be a large problem in everyday life...
  6. ncbi request reprint Members of the national psoriasis foundation: more extensive disease and better informed about treatment options
    Tamar Nijsten
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Arch Dermatol 141:19-26. 2005
    ..Our objective was to assess the extent to which NPF members differ from nonmember patients with psoriasis in their knowledge and use of therapies...
  7. ncbi request reprint Dermatologists and office-based care of dermatologic disease in the 21st century
    Robert S Stern
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    J Investig Dermatol Symp Proc 9:126-30. 2004
    ..The organization of their practices has changed little. Dermatologists dominate the care of many of the same diagnoses as they did 20 y ago...
  8. ncbi request reprint Chronic medication use and inflammatory skin diseases: the power and limitations of the case-control study
    Robert S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Invest Dermatol 127:2709-10. 2007
    ..Hypothesis-driven case-control studies provide what is probably the most efficient but far from easy method to evaluate and quantify observations from case reports and case series that suggest a drug etiology for chronic skin diseases...
  9. doi request reprint Prevalence of a history of skin cancer in 2007: results of an incidence-based model
    Robert S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
    Arch Dermatol 146:279-82. 2010
    ....
  10. doi request reprint Psoriasis is not a useful independent risk factor for cardiovascular disease
    Robert S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Invest Dermatol 130:917-9. 2010
    ..Even if--after accounting for confounding and bias--psoriasis is significantly associated with CVD risk, psoriasis is unlikely to be a clinically useful independent risk factor for CVD...
  11. doi request reprint Very severe psoriasis is associated with increased noncardiovascular mortality but not with increased cardiovascular risk
    Robert S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Invest Dermatol 131:1159-66. 2011
    ..These increases were not significant for CVD. Our data do not support the hypothesis that severe psoriasis is an independent risk factor for CVD. However, exceptionally severe psoriasis is associated with increased all-cause mortality...
  12. ncbi request reprint Managed care and the treatment of skin disease, 1995. Continued growth and emerging dominance
    R S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, MA, USA
    Arch Dermatol 134:1089-91. 1998
    ..To document changes in type of financing for office-based visits for the treatment of common skin conditions and to dermatologists...
  13. ncbi request reprint Risk of squamous cell carcinoma and methoxsalen (psoralen) and UV-A radiation (PUVA). A meta-analysis
    R S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass, USA
    Arch Dermatol 134:1582-5. 1998
    ..To assess the risk of squamous cell carcinoma (SCC) and the relation of dose to risk among groups of patients with psoriasis exposed to psoralen-UV-A (PUVA)...
  14. ncbi request reprint Photocarcinogenicity of drugs
    R S Stern
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Toxicol Lett 102:389-92. 1998
    ..These data suggest that at least some photosensitizing chemicals can substantially increase the risk of skin cancer in humans, but long-term multiple exposures appear to be necessary for a clinical meaningful increase of risk...
  15. ncbi request reprint Lymphoma risk in psoriasis: results of the PUVA follow-up study
    Robert S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Arch Dermatol 142:1132-5. 2006
    ..To assess the risk of lymphoma in patients with psoriasis...
  16. ncbi request reprint Clinical practice. Treatment of photoaging
    Robert S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
    N Engl J Med 350:1526-34. 2004
  17. ncbi request reprint The persistent risk of genital tumors among men treated with psoralen plus ultraviolet A (PUVA) for psoriasis
    Robert S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    J Am Acad Dermatol 47:33-9. 2002
    ..Since that time, fewer cohort patients have used PUVA, and genital protection among PUVA users is likely to be frequent...
  18. ncbi request reprint Incidence and risk factors associated with a second squamous cell carcinoma or basal cell carcinoma in psoralen + ultraviolet a light-treated psoriasis patients
    Kenneth A Katz
    Harvard Medical School, Boston, Massachusetts 02115, USA
    J Invest Dermatol 118:1038-43. 2002
    ..Patients who develop a squamous cell carcinoma after starting psoralen + ultraviolet A therapy should be closely monitored for a subsequent squamous cell carcinoma...
  19. ncbi request reprint High levels of ultraviolet B exposure increase the risk of non-melanoma skin cancer in psoralen and ultraviolet A-treated patients
    Jean Lee Lim
    Harvard Medical School, Boston, Massachusetts 02215, USA
    J Invest Dermatol 124:505-13. 2005
    ..For adults with high UVB exposure levels, UVB confers a modest increase in NMSC risk, much less than that observed with PUVA. Therefore, UVB remains a relatively low-risk treatment for psoriasis...
  20. ncbi request reprint The risk of melanoma in association with long-term exposure to PUVA
    R S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    J Am Acad Dermatol 44:755-61. 2001
    ..This risk is greater in patients exposed to high doses of PUVA, appears to be increasing with the passage of time, and should be considered in determining the risks and benefits of this therapy...
  21. ncbi request reprint The increased risk of skin cancer is persistent after discontinuation of psoralen+ultraviolet A: a cohort study
    Tamar E C Nijsten
    Department of Dermatology, Beth Israel Deaconess, Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Invest Dermatol 121:252-8. 2003
    ....
  22. ncbi request reprint Oral retinoid use reduces cutaneous squamous cell carcinoma risk in patients with psoriasis treated with psoralen-UVA: a nested cohort study
    Tamar E C Nijsten
    Department of Dermatology, Beth Israel Deaconess, Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Am Acad Dermatol 49:644-50. 2003
    ..Oral retinoids are used to treat psoriasis. We performed a nested cohort study to assess whether oral retinoids reduce skin cancer risk among patients with psoriasis exposed to psoralen-UVA...
  23. ncbi request reprint Squamous-cell cancer of the skin in patients given PUVA and ciclosporin: nested cohort crossover study
    I Marcil
    Department of Dermatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Lancet 358:1042-5. 2001
    ..Such risks should be balanced against the effectiveness of the drug and possible newer immunosuppressive agents...
  24. ncbi request reprint Inpatient hospital care for psoriasis: a vanishing practice in the United States
    Robert S Stern
    Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Am Acad Dermatol 49:445-50. 2003
    ..Inpatient hospital care was a traditional approach to treat severe psoriasis. Since 1980, only modest innovations in psoriasis therapy have been introduced, but regulation and financing of inpatient hospital care have changed greatly...
  25. ncbi request reprint Traditional systemic treatments have not fully met the needs of psoriasis patients: results from a national survey
    Tamar Nijsten
    Department of Dermatology at Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Am Acad Dermatol 52:434-44. 2005
    ..Many psoriasis patients are dissatisfied with current therapies. However, patient-centered levels of satisfaction with individual treatments have not been well described...
  26. ncbi request reprint Actinic degeneration and pigmentary change in association with psoralen and UVA treatment: a 20-year prospective study
    Robert S Stern
    Beth Israel Deaconess Medical Center, Department of Dermatology, Boston, Massachusetts 02215, USA
    J Am Acad Dermatol 48:61-7. 2003
    ..Changes in the appearance of the skin including actinic degeneration and pigmentary changes have been noted in patients treated with psoralen and UVA (PUVA)...
  27. ncbi request reprint Use of biological agents in patients with moderate to severe psoriasis: a cohort-based perspective
    Maria Jones-Caballero
    Department of Dermatology, Beth Israel Deaconess Medical Center, GZ 522, 330 Brookline Ave, Boston, MA 02215, USA
    Arch Dermatol 143:846-50. 2007
    ..To compare characteristics of patients enrolled in a long-term multicenter cohort trial who had used biological therapies for treatment of psoriasis with those who had not used these agents...
  28. ncbi request reprint Medicare reimbursement policy and teaching physicians' behavior in hospital clinics: the changes of 1996
    Robert S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, and Department of Dermatology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Acad Med 77:65-71. 2002
    ..To determine the frequency of attending physicians' contacts with residents' patients in hospital-based outpatient clinics and changes in these practices after June 1996...
  29. ncbi request reprint Growth of international contributors to dermatologic literature
    R S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Mass 02115, USA
    Arch Dermatol 135:1074-6. 1999
    ..The growth of dermatology in many additional countries has set the stage for a broader national representation of the authorship of the most frequently cited dermatologic articles...
  30. ncbi request reprint Managed care and the treatment of skin diseases. Dermatologists do it less often
    R S Stern
    Department of Dermatology, Beth Israel Hospital, Harvard Medical School, Boston, Mass, USA
    Arch Dermatol 132:1039-42. 1996
    ..The changing source of payment for all office visits and visits for skins diseases as a result of managed care is assessed...
  31. ncbi request reprint Medication and medical service utilization for acne 1995-1998
    R S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215 5491, USA
    J Am Acad Dermatol 43:1042-8. 2000
    ..Acne occurs in most persons sometime during adolescence or early adulthood and is a frequent reason for visits to dermatologists and for prescription drug therapy...
  32. ncbi request reprint Classic and near-classic articles in the dermatologic literature
    R S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Arch Dermatol 135:948-50. 1999
    ..The nature of dermatologic articles cited fewer than 100 times but still much more frequently cited than average has not been clearly elucidated...
  33. ncbi request reprint The impact of psoriasis on quality of life: results of a 1998 National Psoriasis Foundation patient-membership survey
    G Krueger
    Department of Dermatology, University of Utah Medical School, 50 N Medical Dr, Salt Lake City, UT 84132, USA
    Arch Dermatol 137:280-4. 2001
    ..Physicians may need to improve communication with their patients and should reevaluate their management of psoriasis...
  34. ncbi request reprint Lack of consensus among experts on the choice of UV therapy for psoriasis
    R S Stern
    Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass 02215, USA
    Arch Dermatol 135:1187-92. 1999
    ..Although PUVA is generally considered more effective, it is also more toxic and more expensive. The degree of consensus among experts in prescribing these alternative treatments has not been quantified...
  35. ncbi request reprint Utilization of hospital and outpatient care for adverse cutaneous reactions to medications
    Robert S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
    Pharmacoepidemiol Drug Saf 14:677-84. 2005
    ..To quantify hospitalizations, visits to office based physicians, hospital clinics and emergency departments with primary diagnoses of skin conditions that are often due to drug reaction...
  36. ncbi request reprint Psoralen plus ultraviolet A does not increase the risk of cataracts: a 25-year prospective study
    Dimitrios Malanos
    Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Am Acad Dermatol 57:231-7. 2007
    ..The relevance of these animal findings to human beings is not established. However, some case reports suggest that PUVA in human beings may increase the risk of lens abnormalities...
  37. ncbi request reprint Top-cited dermatology authors publishing in 5 "high-impact" general medical journals
    R S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Mass 02215, USA
    Arch Dermatol 136:357-61. 2000
    ..In addition to publishing in the dermatologic literature, some dermatologists also publish articles in the general medical journals, which enjoy wide circulation and whose articles are often cited...
  38. ncbi request reprint Usefulness of case report literature in determining drugs responsible for toxic epidermal necrolysis
    R S Stern
    Department of Dermatology, Beth Israel Hospital, Harvard Medical School, Boston, MA 02215
    J Am Acad Dermatol 21:317-22. 1989
    ..We propose a minimum set of informational and specific diagnostic criteria...
  39. ncbi request reprint p53 mutation in nonmelanoma skin cancers occurring in psoralen ultraviolet a-treated patients: evidence for heterogeneity and field cancerization
    Robert S Stern
    Department of Dermatology, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    J Invest Dermatol 119:522-6. 2002
    ....
  40. ncbi request reprint Impact of psoriasis on health-related quality of life decreases over time: an 11-year prospective study
    Jane Unaeze
    Harvard Medical School, Boston, Massachusetts, USA
    J Invest Dermatol 126:1480-9. 2006
    ..05). In this large cohort interviewed independent of treatments and psoriasis status, impact of psoriasis on HRQOL decreases over time. For chronic diseases, HRQOL is best measured over time and independently of seeking treatment...
  41. ncbi request reprint Epidemiology of psoriatic arthritis in the population of the United States
    Joel M Gelfand
    Department of Dermatology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Am Acad Dermatol 53:573. 2005
    ..Estimates of the prevalence of psoriatic arthritis vary widely and are usually not determined by population-based studies...
  42. ncbi request reprint The reduced Impact of Psoriasis Questionnaire has good psychometric properties in Italian patients
    Tamar Nijsten
    Department of Dermatology, Erasmus MC, Rotterdam, The Netherlands
    Dermatology 215:348-51. 2007
    ..A recent refinement study suggested that a Rasch reduced version of the Impact of Psoriasis Questionnaire (IPSO) of 11 items most adequately assessed the psychosocial impact of US psoriasis patients...
  43. ncbi request reprint The prevalence of psoriasis in African Americans: results from a population-based study
    Joel M Gelfand
    Department of Dermatology and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, PA 19104, USA
    J Am Acad Dermatol 52:23-6. 2005
    ..The prevalence of psoriasis in African Americans has been previously reported as rare. However, there have been no population-based studies to assess the prevalence and burden of psoriasis in African Americans...
  44. ncbi request reprint The risk of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with nonsteroidal antiinflammatory drugs: a multinational perspective
    Maja Mockenhaupt
    Dokumentationszentrum schwerer Hautreaktionen, Freiburg, Germany
    J Rheumatol 30:2234-40. 2003
    ..To quantify the risk of the severe cutaneous adverse reactions Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) associated with use of nonsteroidal antiinflammatory drugs (NSAID)...
  45. ncbi request reprint A promising step forward in psoriasis therapy
    Robert S Stern
    JAMA 290:3133-5. 2003
  46. ncbi request reprint Assessing the safety of immunologic modifiers for the treatment of chronic disease: the psoriasis paradigm
    Robert S Stern
    J Invest Dermatol 120:xi-xii. 2003
  47. ncbi request reprint Insuring rapid and robust safety assessment
    Robert S Stern
    J Invest Dermatol 122:857-8. 2004
  48. ncbi request reprint Questions & answers. Of all the treatments that promise to improve the appearance of aging skin, which ones have been medically proven to actually work?
    Robert S Stern
    Health News 10:16. 2004
  49. ncbi request reprint Determinants of quality of life in patients with psoriasis: a study from the US population
    Joel M Gelfand
    Department of Dermatology and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, USA
    J Am Acad Dermatol 51:704-8. 2004
    ..Psoriasis is a common disease with substantial effects on quality of life. Few quality of life studies have been performed in psoriasis patients from the general US population...
  50. ncbi request reprint Clinical severity of psoriasis in last 20 years of PUVA study
    Tamar Nijsten
    Department of Dermatology, Erasmus Medical Center, Rotterdam, The Netherlands
    Arch Dermatol 143:1113-21. 2007
    ..To assess the severity of psoriasis over time...
  51. ncbi request reprint The psychometric properties of the psoriasis disability index in United States patients
    Tamar Nijsten
    Department of Dermatology, University Hospital Antwerp, Antwerp, Belgium
    J Invest Dermatol 125:665-72. 2005
    ..The psychometric properties of instruments designed to measure the impact of psoriasis should be tested in populations in which the instrument is to be applied...
  52. ncbi request reprint Reported use of photosensitizing medications and basal cell and squamous cell carcinoma of the skin: results of a population-based case-control study
    Margaret R Karagas
    J Invest Dermatol 127:2901-3. 2007
  53. ncbi request reprint Severe cutaneous reactions to sulfadoxine-pyrimethamine and trimethoprim-sulfamethoxazole in Blantyre District, Malawi
    John E Gimnig
    Division of Parasitic Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Am J Trop Med Hyg 74:738-43. 2006
    ..4 cases per 100,000 CTX exposures). Infrequent treatment doses with SP are associated with a low risk of an adverse cutaneous reaction, and SP can be recommended for treatment of malaria in areas where P. falciparum is susceptible...