Meir J Stampfer

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Risk factor criteria
    Meir J Stampfer
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, Mass 02115, USA
    Circulation 109:IV3-5. 2004
  2. pmc Plasma selenium, manganese superoxide dismutase, and intermediate- or high-risk prostate cancer
    June M Chan
    Department of Epidemiology, University of California, San Francisco, San Francisco, CA, USA
    J Clin Oncol 27:3577-83. 2009
  3. pmc Hyperglycemia, insulin resistance, impaired pancreatic β-cell function, and risk of pancreatic cancer
    Brian M Wolpin
    Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02215, USA
    J Natl Cancer Inst 105:1027-35. 2013
  4. pmc Dietary glycemic index, dietary glycemic load, blood lipids, and C-reactive protein
    Emily B Levitan
    Cardiovascular Epidemiology Research Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Metabolism 57:437-43. 2008
  5. pmc Prospective study of prostate tumor angiogenesis and cancer-specific mortality in the health professionals follow-up study
    Lorelei A Mucci
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 27:5627-33. 2009
  6. pmc Risk factors for prostate cancer incidence and progression in the health professionals follow-up study
    Edward Giovannucci
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02115, USA
    Int J Cancer 121:1571-8. 2007
  7. pmc A large prospective study of SEP15 genetic variation, interaction with plasma selenium levels, and prostate cancer risk and survival
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Prev Res (Phila) 3:604-10. 2010
  8. pmc Prediagnostic body mass index and pancreatic cancer survival
    Chen Yuan
    Chen Yuan, Shuji Ogino, Kimmie Ng, Zhi Rong Qian, Douglas A Rubinson, and Brian M Wolpin, Dana Farber Cancer Institute Ying Bao, Shuji Ogino, Kimmie Ng, Meir J Stampfer, Edward L Giovannucci, and Brian M Wolpin, Brigham and Women s Hospital, Harvard Medical School and Chen Wu, Peter Kraft, Shuji Ogino, Meir J Stampfer, and Edward L Giovannucci, Harvard School of Public Health, Boston, MA
    J Clin Oncol 31:4229-34. 2013
  9. pmc Testing a multigene signature of prostate cancer death in the Swedish Watchful Waiting Cohort
    Lorelei A Mucci
    Channing Laboratory, Brigham and Women s Hospital, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:1682-8. 2008
  10. pmc α-Methylacyl-CoA racemase expression and lethal prostate cancer in the Physicians' Health Study and Health Professionals Follow-up Study
    Marc Barry
    Department of Pathology, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
    Prostate 72:301-6. 2012

Collaborators

Detail Information

Publications133 found, 100 shown here

  1. ncbi request reprint Risk factor criteria
    Meir J Stampfer
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, Mass 02115, USA
    Circulation 109:IV3-5. 2004
  2. pmc Plasma selenium, manganese superoxide dismutase, and intermediate- or high-risk prostate cancer
    June M Chan
    Department of Epidemiology, University of California, San Francisco, San Francisco, CA, USA
    J Clin Oncol 27:3577-83. 2009
    ..We now hypothesized that SOD2 modifies the association between selenium level and risk of aggressive prostate cancer at diagnosis...
  3. pmc Hyperglycemia, insulin resistance, impaired pancreatic β-cell function, and risk of pancreatic cancer
    Brian M Wolpin
    Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02215, USA
    J Natl Cancer Inst 105:1027-35. 2013
    ..Hemoglobin A1c (HbA1c) is a measure of hyperglycemia, whereas plasma insulin and proinsulin are markers of peripheral insulin resistance, and the proinsulin to insulin ratio marks pancreatic β-cell dysfunction...
  4. pmc Dietary glycemic index, dietary glycemic load, blood lipids, and C-reactive protein
    Emily B Levitan
    Cardiovascular Epidemiology Research Unit, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Metabolism 57:437-43. 2008
    ..24, and TG = 13 mg/dL). Differences in blood lipids and CRP between extreme quintiles of dietary GI and GL were small, but may translate into a clinically meaningful difference in cardiovascular risk...
  5. pmc Prospective study of prostate tumor angiogenesis and cancer-specific mortality in the health professionals follow-up study
    Lorelei A Mucci
    Channing Laboratory, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 27:5627-33. 2009
    ..We examined whether microvessel morphology contributes to the considerable biologic heterogeneity of prostate cancer...
  6. pmc Risk factors for prostate cancer incidence and progression in the health professionals follow-up study
    Edward Giovannucci
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02115, USA
    Int J Cancer 121:1571-8. 2007
    ..The complexity of the clinical and pathologic manifestations of prostate cancer must be considered in the design and interpretation of studies...
  7. pmc A large prospective study of SEP15 genetic variation, interaction with plasma selenium levels, and prostate cancer risk and survival
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Prev Res (Phila) 3:604-10. 2010
    ..Additionally, the association of selenium with PCa mortality was modified by a variant, suggesting the possibility that some men with PCa may benefit more from selenium than others, depending on their genotype...
  8. pmc Prediagnostic body mass index and pancreatic cancer survival
    Chen Yuan
    Chen Yuan, Shuji Ogino, Kimmie Ng, Zhi Rong Qian, Douglas A Rubinson, and Brian M Wolpin, Dana Farber Cancer Institute Ying Bao, Shuji Ogino, Kimmie Ng, Meir J Stampfer, Edward L Giovannucci, and Brian M Wolpin, Brigham and Women s Hospital, Harvard Medical School and Chen Wu, Peter Kraft, Shuji Ogino, Meir J Stampfer, and Edward L Giovannucci, Harvard School of Public Health, Boston, MA
    J Clin Oncol 31:4229-34. 2013
    ..Although obesity is associated with increased incidence of pancreatic cancer, studies have not prospectively evaluated prediagnostic body mass index (BMI) and survival...
  9. pmc Testing a multigene signature of prostate cancer death in the Swedish Watchful Waiting Cohort
    Lorelei A Mucci
    Channing Laboratory, Brigham and Women s Hospital, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 17:1682-8. 2008
    ..78) than the clinical model alone (area under the curve = 0.71; P = 0.04). Molecular tumor markers can add to clinical variables to help distinguish lethal and indolent prostate cancer and hold promise to guide treatment decisions...
  10. pmc α-Methylacyl-CoA racemase expression and lethal prostate cancer in the Physicians' Health Study and Health Professionals Follow-up Study
    Marc Barry
    Department of Pathology, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
    Prostate 72:301-6. 2012
    ..Recent studies suggest that low AMACR expression is associated with biochemical recurrence and the development of fatal disease...
  11. pmc Prediagnostic body-mass index, plasma C-peptide concentration, and prostate cancer-specific mortality in men with prostate cancer: a long-term survival analysis
    Jing Ma
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Lancet Oncol 9:1039-47. 2008
    ..We assessed the effect of prediagnostic BMI and plasma C-peptide concentration (reflecting insulin secretion) on prostate cancer-specific mortality after diagnosis...
  12. ncbi request reprint A prospective study of trans fatty acids in erythrocytes and risk of coronary heart disease
    Qi Sun
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
    Circulation 115:1858-65. 2007
    ..We assessed the hypothesis that higher trans fatty acid contents in erythrocytes were associated with an elevated risk of CHD in a nested case-control study among US women...
  13. pmc Vitamin D-related genetic variation, plasma vitamin D, and risk of lethal prostate cancer: a prospective nested case-control study
    Irene M Shui
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02215, USA
    J Natl Cancer Inst 104:690-9. 2012
    ..The association of vitamin D status with prostate cancer is controversial; no association has been observed for overall incidence, but there is a potential link with lethal disease...
  14. pmc Red meat consumption and mortality: results from 2 prospective cohort studies
    An Pan
    Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Arch Intern Med 172:555-63. 2012
    ..Red meat consumption has been associated with an increased risk of chronic diseases. However, its relationship with mortality remains uncertain...
  15. pmc A single nucleotide polymorphism in inflammatory gene RNASEL predicts outcome after radiation therapy for localized prostate cancer
    Jonathan D Schoenfeld
    Harvard Radiation Oncology Program, Boston, Massachusetts, USA
    Clin Cancer Res 19:1612-9. 2013
    ..To study associations between single nucleotide polymorphisms (SNP) in Ribonuclease L (RNASEL), a gene implicated in inflammation and prostate cancer risk, and outcomes after radiation therapy...
  16. pmc Plasma vitamin B(6) and risk of myocardial infarction in women
    John H Page
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Circulation 120:649-55. 2009
    ..We prospectively evaluated the relationships between fasting plasma levels of vitamin B(6), as pyridoxal phosphate, and subsequent myocardial infarction risk in women...
  17. pmc Major dietary protein sources and risk of coronary heart disease in women
    Adam M Bernstein
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 122:876-83. 2010
    ..Our objective was to examine the relation between foods that are major dietary protein sources and incident CHD...
  18. pmc Circulating prediagnostic interleukin-6 and C-reactive protein and prostate cancer incidence and mortality
    Jennifer Rider Stark
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Int J Cancer 124:2683-9. 2009
    ..02). Adjusted hazard ratios were 1.73 (95% CI: 0.86, 3.51) comparing the highest to lowest IL-6 level. Our study suggests that IL-6 may potentially be involved in the development or progression of prostate cancer...
  19. pmc Seasonal variation in expression of markers in the vitamin D pathway in prostate tissue
    Mara M Epstein
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Cancer Causes Control 23:1359-66. 2012
    ..As serum vitamin D levels vary by season, we sought to determine whether the expression of genes on the vitamin D pathway, assessed in prostate tumor tissue, do the same...
  20. pmc Genetic variation in RNASEL associated with prostate cancer risk and progression
    Mara S Meyer
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Carcinogenesis 31:1597-603. 2010
    ..The results of this study support a link between RNASEL and prostate cancer and suggest that the association may be mediated through inflammation. These novel findings warrant replication in future studies...
  21. pmc Common genetic variation of the calcium-sensing receptor and lethal prostate cancer risk
    Irene M Shui
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 22:118-26. 2013
    ..We assessed whether (i) common genetic variation in CaSR was associated with PCa risk and (ii) these associations varied by calcium intake or plasma 25-hydroxyvitamin D [25(OH)D] levels...
  22. ncbi request reprint Blood levels of long-chain polyunsaturated fatty acids, aspirin, and the risk of colorectal cancer
    Megan N Hall
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Cancer Epidemiol Biomarkers Prev 16:314-21. 2007
    ..Aspirin also inhibits the cyclooxygenase-2 enzyme and may share with n-3 fatty acids a potential mechanism to decrease the risk of colorectal cancer...
  23. pmc Eighteen insulin-like growth factor pathway genes, circulating levels of IGF-I and its binding protein, and risk of prostate and breast cancer
    Fangyi Gu
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 19:2877-87. 2010
    ..Heritable factors explain up to 60% of the variation in IGF-I and IGFBP-3 in studies of adult twins...
  24. pmc Obesity as compared with physical activity in predicting risk of coronary heart disease in women
    Tricia Y Li
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 113:499-506. 2006
    ..The comparative importance of physical inactivity and obesity as predictors of coronary heart disease (CHD) risk remains unsettled...
  25. pmc Intakes of vitamins A, C, and E and use of multiple vitamin supplements and risk of colon cancer: a pooled analysis of prospective cohort studies
    Yikyung Park
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Cancer Causes Control 21:1745-57. 2010
    ..To evaluate the associations between intakes of vitamins A, C, and E and risk of colon cancer...
  26. pmc Fruit and vegetable intake in relation to risk of breast cancer in the Black Women's Health Study
    Deborah A Boggs
    Slone Epidemiology Center at Boston University, Boston, Massachusetts 02215, USA
    Am J Epidemiol 172:1268-79. 2010
    ....
  27. pmc Dietary fat intake and cognitive decline in women with type 2 diabetes
    ELIZABETH E DEVORE
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Diabetes Care 32:635-40. 2009
    ..We investigated whether dietary fat, which modulates glucose and lipid metabolism, might influence cognitive decline in older adults with diabetes...
  28. pmc Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer
    Sunita R Setlur
    Department of Pathology, Brigham and Women s Hospital, Boston, MA, USA
    J Natl Cancer Inst 100:815-25. 2008
    ....
  29. pmc Prospective study of Trichomonas vaginalis infection and prostate cancer incidence and mortality: Physicians' Health Study
    Jennifer R Stark
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Natl Cancer Inst 101:1406-11. 2009
    ..We confirmed these findings in an independent population and related serostatus for antibodies against T vaginalis to prostate cancer incidence and mortality...
  30. pmc Single-nucleotide polymorphisms within the antioxidant defence system and associations with aggressive prostate cancer
    Miyako Abe
    Lank Center for Genitourinary Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    BJU Int 107:126-34. 2011
    ....
  31. ncbi request reprint A prospective cohort study of red wine consumption and risk of prostate cancer
    Siobhan Sutcliffe
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Int J Cancer 120:1529-35. 2007
    ..These findings suggest that red wine does not contribute appreciably to the etiology of prostate cancer...
  32. pmc Polymorphism in endostatin, an angiogenesis inhibitor, and prostate cancer risk and survival: A prospective study
    Lorelei A Mucci
    Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Int J Cancer 125:1143-6. 2009
    ..However, our data indicate that prostate cancer cases who carry the variant N allele are more likely to be overweight, and may be more susceptible to the angiogenic influences of obesity in prostate cancer pathogenesis...
  33. pmc Evaluation of 8q24 and 17q risk loci and prostate cancer mortality
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, Harvard University, Cambridge, Massachusetts, USA
    Clin Cancer Res 15:3223-30. 2009
    ..We investigated whether the 8q24 and 17q risk variants are associated with clinical variables as well as prostate cancer mortality...
  34. pmc Choline intake and risk of lethal prostate cancer: incidence and survival
    Erin L Richman
    Departments of Epidemiology and Nutrition, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 96:855-63. 2012
    ..These foods are sources of choline-a nutrient that may affect prostate cancer progression through cell membrane function and one-carbon metabolism. No study has examined dietary choline and the risk of lethal prostate cancer...
  35. ncbi request reprint A prospective study of soluble tumor necrosis factor-alpha receptor II (sTNF-RII) and risk of coronary heart disease among women with type 2 diabetes
    Iris Shai
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Diabetes Care 28:1376-82. 2005
    ..Tumor necrosis factor-alpha (TNF-alpha), a cytokine secreted by adipose tissue and other cells, might play a role in insulin resistance...
  36. ncbi request reprint Lipoprotein (a) and coronary heart disease among women: beyond a cholesterol carrier?
    Iris Shai
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Eur Heart J 26:1633-9. 2005
    ..We assessed the role of Lp(a) in coronary heart diseases (CHD) by a recently developed assay that is not affected by the plasminogen-like Kringle-type-2 repeats...
  37. pmc Joint association of glycemic load and alcohol intake with type 2 diabetes incidence in women
    Rania A Mekary
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 94:1525-32. 2011
    ..Little is known about the joint association between glycemic index (GI), glycemic load (GL), and alcohol intake with type 2 diabetes (T2D)...
  38. pmc Lack of association between dietary protein intake and risk of stroke among middle-aged men
    Sarah Rosner Preis
    Departments of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 91:39-45. 2010
    ..Prospective cohort studies in Japanese populations have shown an inverse association between dietary protein and stroke risk. However, this association has not been examined among any study populations of US men...
  39. pmc Watchful waiting and quality of life among prostate cancer survivors in the Physicians' Health Study
    Julie L Kasperzyk
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    J Urol 186:1862-7. 2011
    ..We examined patient reported outcomes among patients with prostate cancer treated with watchful waiting in a nationwide cohort...
  40. ncbi request reprint A prospective study of calcium intake and incident and fatal prostate cancer
    Edward Giovannucci
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Harvard School of Public Health, 665 Huntington Avenue, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 15:203-10. 2006
    ....
  41. ncbi request reprint Potato and french fry consumption and risk of type 2 diabetes in women
    Thomas L Halton
    Department of Nutrition and Epidemiology, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02215, USA
    Am J Clin Nutr 83:284-90. 2006
    ..Potatoes, a high glycemic form of carbohydrate, are hypothesized to increase insulin resistance and risk of type 2 diabetes...
  42. pmc A 22-y prospective study of fish intake in relation to prostate cancer incidence and mortality
    Jorge E Chavarro
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 88:1297-303. 2008
    ..Fish and seafood n-3 fatty acids may prevent or delay the progression of prostate cancer, but epidemiologic studies do not uniformly support this hypothesis...
  43. pmc Adherence to a low-risk, healthy lifestyle and risk of sudden cardiac death among women
    Stephanie E Chiuve
    Center for Arrhythmia Prevention, Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    JAMA 306:62-9. 2011
    ..Primary preventive strategies are needed to reduce SCD incidence...
  44. ncbi request reprint Multivariate assessment of lipid parameters as predictors of coronary heart disease among postmenopausal women: potential implications for clinical guidelines
    Iris Shai
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 110:2824-30. 2004
    ..Over the past decade, lipid measurements have been significantly improved and standardized. We evaluated the usefulness of multiple plasma lipid parameters in predicting coronary heart diseases (CHD) among women...
  45. pmc A novel two-stage, transdisciplinary study identifies digoxin as a possible drug for prostate cancer treatment
    Elizabeth A Platz
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Cancer Discov 1:68-77. 2011
    ..54, 95% CI 0.37-0.79, P-trend<0.001), had a lower prostate cancer risk. Digoxin was highly potent in inhibiting prostate cancer cell growth in vitro and its use was associated with a 25% lower prostate cancer risk...
  46. pmc Coffee consumption and prostate cancer risk and progression in the Health Professionals Follow-up Study
    Kathryn M Wilson
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Natl Cancer Inst 103:876-84. 2011
    ..Because of these biological activities, coffee may be associated with a reduced risk of prostate cancer...
  47. pmc mRNA expression signature of Gleason grade predicts lethal prostate cancer
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    J Clin Oncol 29:2391-6. 2011
    ....
  48. pmc Alternative dietary indices both strongly predict risk of chronic disease
    Stephanie E Chiuve
    Department of Medicine, Harvard Medical School, Boston, MA, USA
    J Nutr 142:1009-18. 2012
    ..However, the AHEI-2010, which included additional dietary information, was more strongly associated with chronic disease risk, particularly CHD and diabetes...
  49. pmc Tea and coffee intake in relation to risk of breast cancer in the Black Women's Health Study
    Deborah A Boggs
    Slone Epidemiology Center at Boston University, 1010 Commonwealth Avenue, Boston, MA 02215, USA
    Cancer Causes Control 21:1941-8. 2010
    ..We prospectively examined the relation of tea and coffee consumption to risk of breast cancer among 52,062 women aged 21-69 at enrollment in 1995 in the Black Women's Health Study...
  50. pmc Association of KLK3 (PSA) genetic variants with prostate cancer risk and PSA levels
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Carcinogenesis 32:853-9. 2011
    ..Understanding the mechanism by which genetic variation in KLK3 affects prostate cancer risk has important implications for study of the biological role of PSA in prostate tumorigenesis...
  51. pmc Beta-carotene antioxidant use during radiation therapy and prostate cancer outcome in the Physicians' Health Study
    Danielle N Margalit
    Harvard Radiation Oncology Program, Boston, Massachusetts, USA
    Int J Radiat Oncol Biol Phys 83:28-32. 2012
    ....
  52. ncbi request reprint Predictors of 14-year changes in the total cholesterol to high-density lipoprotein cholesterol ratio in men
    Richard Scranton
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Mass, USA
    Am Heart J 147:1033-8. 2004
    ..We examined predictors of a change in TC/HDL ratio over a period of 14 years among 4451 men free of CVD from the Physicians' Health Study...
  53. ncbi request reprint Dietary fat and meat intake in relation to risk of type 2 diabetes in men
    Rob M van Dam
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Diabetes Care 25:417-24. 2002
    ..To examine dietary fat and meat intake in relation to risk of type 2 diabetes...
  54. pmc Neighborhood socioeconomic status in relation to preterm birth in a U.S. cohort of black women
    Ghasi S Phillips
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    J Urban Health 90:197-211. 2013
    ..Low neighborhood SES was not materially associated with preterm birth in this study of U.S. Black women...
  55. pmc A prospective study of plasma adiponectin and pancreatic cancer risk in five US cohorts
    Ying Bao
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 105:95-103. 2013
    ..Although development of pancreatic cancer is associated with states of insulin resistance and chronic inflammation, the mechanistic basis of the associations is poorly understood...
  56. pmc Selenoprotein P genetic variants and mrna expression, circulating selenium, and prostate cancer risk and survival
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Prostate 73:700-5. 2013
    ..We examined the association of SEPP1 single nucleotide polymorphisms (SNPs) with PCa risk and survival, and tested for interactions...
  57. pmc Egg, red meat, and poultry intake and risk of lethal prostate cancer in the prostate-specific antigen-era: incidence and survival
    Erin L Richman
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Cancer Prev Res (Phila) 4:2110-21. 2011
    ..45; 95% CI: 0.73-2.87; P(trend): 0.08) and risk of progression of localized prostate cancer to lethal disease. In conclusion, consumption of eggs may increase risk of developing a lethal form of prostate cancer among healthy men...
  58. pmc Light-to-moderate alcohol consumption and risk of sudden cardiac death in women
    Stephanie E Chiuve
    Center for Arrhythmia Prevention, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Heart Rhythm 7:1374-80. 2010
    ..In men, heavy alcohol consumption may increase risk of SCD, whereas light-to-moderate alcohol intake may lower risk. There are no parallel data among women...
  59. ncbi request reprint Dietary intakes of flavonols and flavones and coronary heart disease in US women
    Jennifer Lin
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
    Am J Epidemiol 165:1305-13. 2007
    ..93; p for trend = 0.04). The lower risk associated with kaempferol intake was probably attributable to broccoli consumption. These prospective data do not support an inverse association between flavonol or flavone intake and CHD risk...
  60. ncbi request reprint Long-term aspirin use and mortality in women
    Andrew T Chan
    Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 0214, USA
    Arch Intern Med 167:562-72. 2007
    ..The influence of long-term use of aspirin on total mortality in women remains uncertain...
  61. ncbi request reprint Hypoxia-inducible factor-1alpha (HIF-1alpha) gene polymorphisms, circulating insulin-like growth factor binding protein (IGFBP)-3 levels and prostate cancer
    Haojie Li
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
    Prostate 67:1354-61. 2007
    ....
  62. pmc Perinatal factors and adult-onset lupus
    Julia F Simard
    Department of Epidemiology, Harvard University School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Arthritis Rheum 59:1155-61. 2008
    ..Therefore, we evaluated the role of birth weight, being breastfed, and preterm birth on the incidence of SLE in participants in the Nurses' Health Study (NHS) and the Nurses' Health Study II (NHSII)...
  63. pmc Vitamin D receptor protein expression in tumor tissue and prostate cancer progression
    Whitney K Hendrickson
    Department of Nutrition, Harvard School of Public Health, 655 Huntington Ave, Boston, MA 02115, USA
    J Clin Oncol 29:2378-85. 2011
    ..How VDR expression in tumor tissue may influence prostate cancer progression has not been evaluated in large studies...
  64. ncbi request reprint Statin drugs and risk of advanced prostate cancer
    Elizabeth A Platz
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Rm E6138, 615 N Wolfe St, Baltimore, MD 21205, USA
    J Natl Cancer Inst 98:1819-25. 2006
    ..We investigated the association of statin use with total and advanced prostate cancer, the latter being the most important endpoint to prevent...
  65. ncbi request reprint Ethnicity, obesity, and risk of type 2 diabetes in women: a 20-year follow-up study
    Iris Shai
    Department of Epidemiology, Harvard School of Public Health, Epidemiology, 677 Huntington Ave, Boston, MA 02115, USA
    Diabetes Care 29:1585-90. 2006
    ..To examine ethnic differences in risk of type 2 diabetes, taking dietary and lifestyle risk factors into account...
  66. ncbi request reprint Alcohol intake and methylenetetrahydrofolate reductase polymorphism modify the relation of folate intake to plasma homocysteine
    Stephanie E Chiuve
    Department of Nutrition and the Channing Laboratory, Harvard Medical School, Boston, MA, USA
    Am J Clin Nutr 82:155-62. 2005
    ..Folate metabolism may be altered by alcohol intake and 2 common polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, 677C-->T and 1298A-->C...
  67. ncbi request reprint Coffee consumption and coronary heart disease in men and women: a prospective cohort study
    Esther Lopez-Garcia
    Department of Nutrition and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Circulation 113:2045-53. 2006
    ..We examined the association between long-term habitual coffee consumption and risk of coronary heart disease (CHD)...
  68. ncbi request reprint Sex steroid hormones and the androgen receptor gene CAG repeat and subsequent risk of prostate cancer in the prostate-specific antigen era
    Elizabeth A Platz
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Room E6138, 615 North Wolfe Street, Baltimore, MD 21205, USA
    Cancer Epidemiol Biomarkers Prev 14:1262-9. 2005
    ..We investigated plasma levels of sex steroid hormones and length of the androgen receptor gene CAG repeat in relation to incident prostate cancer diagnosed in the prostate-specific antigen (PSA) era...
  69. ncbi request reprint Prospective study of predictors of vitamin D status and cancer incidence and mortality in men
    Edward Giovannucci
    Department of Medicine, Harvard Medical School, Brigham and Women s Hospital, Boston, MA, USA
    J Natl Cancer Inst 98:451-9. 2006
    ....
  70. ncbi request reprint Folate, vitamin B6, and B12 intakes in relation to risk of stroke among men
    Ka He
    Department of Nutrition, Harvard School of Public Health, Boston, Mass, USA
    Stroke 35:169-74. 2004
    ..However, the effects of intakes of these vitamins on risk of stroke are still uncertain. This study examines intakes of folate, vitamin B6, and B12 in relation to risk of ischemic and hemorrhagic stroke...
  71. ncbi request reprint Prospective study of major dietary patterns and stroke risk in women
    Teresa T Fung
    Department of Nutrition, Simmons College, 300 The Fenway, Boston, MA 02115, USA
    Stroke 35:2014-9. 2004
    ..Many foods have been suggested to influence the risk of stroke. However, no previous studies have examined the relationship between overall dietary patterns and risk of stroke...
  72. ncbi request reprint Plasma carotenoids and tocopherols and risk of myocardial infarction in a low-risk population of US male physicians
    A Elisabeth Hak
    Department of Epidemiology, Harvard School of Public Health, Channing Laboratory, 181 Longwood Ave, Boston, Mass 02115 5804, USA
    Circulation 108:802-7. 2003
    ..Increased intake of carotenoids and vitamin E may protect against myocardial infarction (MI). However, prospective data on blood levels of carotenoids other than beta-carotene and vitamin E (tocopherol) and risk of MI are sparse...
  73. ncbi request reprint A prospective study of TaqIB polymorphism in the gene coding for cholesteryl ester transfer protein and risk of myocardial infarction in middle-aged men
    Simin Liu
    Division of Preventive Medicine, Department of Medicine, Center for Cardiovascular Disease Prevention, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Atherosclerosis 161:469-74. 2002
    ..However, whether this polymorphism is associated with risk of myocardial infarction (MI) is uncertain...
  74. ncbi request reprint Body iron stores and their determinants in healthy postmenopausal US women
    Jian meng Liu
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
    Am J Clin Nutr 78:1160-7. 2003
    ..Data on the determinants of body iron stores in middle-aged women are sparse...
  75. ncbi request reprint Cholesterol and the risk of ischemic stroke
    Thomas S Bowman
    Harvard University General Internal Medicine Fellowship Program, Veterans Affairs Boston Healthcare System Massachusetts Veterans Affairs Epidemiology, Research, and Information Center, Boston, MA 02130, USA
    Stroke 34:2930-4. 2003
    ....
  76. ncbi request reprint Association between the Met326Ile polymorphism of the p85alpha regulatory subunit of phosphatidylinositol 3-kinase and prostate cancer risk: a prospective study
    Aimée E Paradis
    The Lank Center for Genitourinary Oncology, Department of Adult Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 12:172-3. 2003
  77. ncbi request reprint Breastfeeding during infancy and the risk of cardiovascular disease in adulthood
    Janet W Rich-Edwards
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, Massachusetts 02215, USA
    Epidemiology 15:550-6. 2004
    ..Only 2 studies have evaluated the relation between having been breastfed and the risk of adult cardiovascular events...
  78. ncbi request reprint Folate intake and the risk of incident hypertension among US women
    John P Forman
    Renal Division, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass, USA
    JAMA 293:320-9. 2005
    ..Folate has important beneficial effects on endothelial function, but there is limited information about folate intake and risk of incident hypertension...
  79. ncbi request reprint Early life risk factors in cancer: the relation of birth weight to adult obesity
    Nicole M Leong
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Int J Cancer 103:789-91. 2003
    ..76). These data suggest that both low and high birth weights are associated with higher adult BMI and support the hypothesis that fetal experience may influence adult obesity with potential consequences for risk of several major cancers...
  80. ncbi request reprint Kidney dysfunction, inflammation, and coronary events: a prospective study
    Eric L Knight
    Channing Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Soc Nephrol 15:1897-903. 2004
    ..These findings warrant further investigation in other populations...
  81. ncbi request reprint Plasma insulin-like growth factor-1 and binding protein-3 and subsequent risk of prostate cancer in the PSA era
    Elizabeth A Platz
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health and the Brady Urological Institute and the Kimmel Comprehensive Cancer Center, Baltimore, MD 21205, USA
    Cancer Causes Control 16:255-62. 2005
    ..We prospectively investigated the associations of plasma IGF-1 and IGFBP-3 concentrations with prostate cancer detected in the PSA era...
  82. ncbi request reprint Effects of moderate alcohol consumption on cognitive function in women
    Meir J Stampfer
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, USA
    N Engl J Med 352:245-53. 2005
    ..The adverse effects of excess alcohol intake on cognitive function are well established, but the effect of moderate consumption is uncertain...
  83. ncbi request reprint ATAAA repeat upstream of glutathione S-transferase P1 and prostate cancer risk
    Elizabeth A Platz
    Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland 21205, USA
    Urology 59:159-64. 2002
    ..Upstream of its promoter is a polymorphic ATAAA repeat of unknown functional significance. We evaluated whether this polymorphism is associated with prostate cancer...
  84. ncbi request reprint Inflammatory markers and the risk of coronary heart disease in men and women
    Jennifer K Pai
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 351:2599-610. 2004
    ..The value of these inflammatory markers as independent predictors remains controversial...
  85. ncbi request reprint Whole-grain intake and the risk of type 2 diabetes: a prospective study in men
    Teresa T Fung
    Programs in Nutrition, Simmons College, Boston, MA 02115, USA
    Am J Clin Nutr 76:535-40. 2002
    ..Certain dietary components may play a role in the prevention of type 2 diabetes...
  86. ncbi request reprint Vitamin D intake and risk of incident hypertension: results from three large prospective cohort studies
    John P Forman
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Hypertension 46:676-82. 2005
    ..We conclude that higher intake of vitamin D is not associated with a lower risk of incident hypertension...
  87. ncbi request reprint Fatty acid intake and incident nephrolithiasis
    Eric N Taylor
    Channing Laboratory and Renal Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Am J Kidney Dis 45:267-74. 2005
    ..It has been proposed that greater intake of EPA and DHA (through dietary sources or fish oil supplementation) may reduce the risk for kidney stone formation...
  88. ncbi request reprint Dietary factors and the risk of incident kidney stones in men: new insights after 14 years of follow-up
    Eric N Taylor
    Department of Medicine, Channing Laboratory, Third Floor, Brigham and Women s Hospital, 181 Longwood Avenue, Boston, MA 02115, USA
    J Am Soc Nephrol 15:3225-32. 2004
    ..Because age and body size affect the relation between diet and kidney stones, dietary recommendations for stone prevention should be tailored to the individual patient...
  89. ncbi request reprint Habitual caffeine intake and the risk of hypertension in women
    Wolfgang C Winkelmayer
    Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    JAMA 294:2330-5. 2005
    ..Caffeine acutely increases blood pressure, but the association between habitual consumption of caffeinated beverages and incident hypertension is uncertain...
  90. pmc Body mass index before and after breast cancer diagnosis: associations with all-cause, breast cancer, and cardiovascular disease mortality
    Hazel B Nichols
    Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Cancer Epidemiol Biomarkers Prev 18:1403-9. 2009
    ..Factors related to improving outcomes in breast cancer survivors are of increasing public health significance. We examined postdiagnosis weight change in relation to mortality risk in a cohort of breast cancer survivors...
  91. ncbi request reprint Mercury and the risk of coronary heart disease in men
    Kazuko Yoshizawa
    Department of Nutrition, Harvard School of Public Health, Boston, USA
    N Engl J Med 347:1755-60. 2002
    ..A high dietary intake of mercury from consumption of fish has been hypothesized to increase the risk of coronary heart disease...
  92. ncbi request reprint Dietary patterns and risk for type 2 diabetes mellitus in U.S. men
    Rob M van Dam
    Harvard School of Public Health, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts 02115, USA
    Ann Intern Med 136:201-9. 2002
    ..The role of diet in the development of type 2 diabetes mellitus remains unsettled...
  93. ncbi request reprint Coffee consumption and risk for type 2 diabetes mellitus
    Eduardo Salazar-Martinez
    Harvard School of Public Health, Channing Laboratory, Harvard Medical School, and Brigham and Women s Hospital, Boston, Massachusetts 02215, USA
    Ann Intern Med 140:1-8. 2004
    ..In small, short-term studies, acute administration of caffeine decreases insulin sensitivity and impairs glucose tolerance...
  94. ncbi request reprint High prevalence of hyperhomocysteinemia in Chinese adults is associated with low folate, vitamin B-12, and vitamin B-6 status
    Ling Hao
    Institute of Reproductive and Child Health, Peking University, Beijing 100083, China, and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Nutr 137:407-13. 2007
    ..Low plasma concentrations of folate, vitamins B-12 and B-6, older age, being male, and living in urban areas were all independently associated with elevated tHcy, with low folate as the strongest determinant...
  95. ncbi request reprint Dyslipidemia and the risk of incident hypertension in men
    Ruben O Halperin
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Hypertension 47:45-50. 2006
    ..These prospective cohort data suggest that dyslipidemias may lead to the subsequent development of hypertension. Thus, plasma lipids may be useful in the identification of men at risk for hypertension...
  96. ncbi request reprint Blood levels of long-chain n-3 fatty acids and the risk of sudden death
    Christine M Albert
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215 1204, USA
    N Engl J Med 346:1113-8. 2002
    ..Whether long-chain n-3 fatty acids are also associated with the risk of sudden death in those without a history of cardiovascular disease is unknown...
  97. ncbi request reprint Diabetes mellitus and the risk of nephrolithiasis
    Eric N Taylor
    Channing Laboratory, and Renal Division, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Kidney Int 68:1230-5. 2005
    ..Existing cross-sectional data on the association between DM and nephrolithiasis are limited, and no prospective study to date has evaluated the relation between DM and the risk of kidney stones...
  98. ncbi request reprint Reproductive and menopausal factors and risk of systemic lupus erythematosus in women
    Karen H Costenbader
    Robert B Brigham Arthritis and Musculoskeletal Diseases Clinical Research Center, Brigham and Women s Hospital, and Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Arthritis Rheum 56:1251-62. 2007
    ..This study was carried out to examine associations between female reproductive and menopausal factors and the development of SLE...
  99. pmc Genetic variation in the HSD17B1 gene and risk of prostate cancer
    Peter Kraft
    Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Genet 1:e68. 2005
    ..These results suggest that the germline variants in HSD17B1 characterized by these htSNPs do not substantially influence the risk of prostate cancer in U.S. and European whites...
  100. ncbi request reprint Dairy consumption and risk of type 2 diabetes mellitus in men: a prospective study
    Hyon K Choi
    Department of Medicine, Massachusetts General Hospital, Boston, Mass 02114, USA
    Arch Intern Med 165:997-1003. 2005
    ..While a strong inverse association has been reported between dairy consumption and the insulin resistance syndrome among young obese adults, the relation between dairy intake and type 2 diabetes is unknown...
  101. pmc Longitudinal study of birth weight and adult body mass index in predicting risk of coronary heart disease and stroke in women
    Janet W Rich-Edwards
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Avenue, Boston, MA 02215, USA
    BMJ 330:1115. 2005
    ..To determine whether birth weight and adult body size interact to predict coronary heart disease in women, as has been observed for men. To determine whether birth weight and adult body size interact to predict risk of stroke...