DONNA L SPIEGELMAN

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Association between low birth weight and infant mortality in children born to human immunodeficiency virus 1-infected mothers in Tanzania
    Ruilan Wei
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Pediatr Infect Dis J 23:530-5. 2004
  2. ncbi request reprint Point and interval estimates of partial population attributable risks in cohort studies: examples and software
    D Spiegelman
    Department of Epidemiology, School of Public Health, Harvard University, 677 Huntington Avenue, Boston, MA 02115, USA
    Cancer Causes Control 18:571-9. 2007
  3. pmc Plasma 25-hydroxyvitamin D and risk of breast cancer in the Nurses' Health Study II
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Breast Cancer Res 13:R50. 2011
  4. pmc Gender-related differences in the prevalence of cardiovascular disease risk factors and their correlates in urban Tanzania
    Marina A Njelekela
    Department of Physiology, Muhimbili University of Health and Allied Sciences, PO Box 65001, Dar es Salaam, Tanzania
    BMC Cardiovasc Disord 9:30. 2009
  5. pmc Correcting for bias in relative risk estimates due to exposure measurement error: a case study of occupational exposure to antineoplastics in pharmacists
    D Spiegelman
    Department of Epidemiology, Harvard School of Public Health, Boston, Mass 02115, USA
    Am J Public Health 88:406-12. 1998
  6. ncbi request reprint Correlated errors in biased surrogates: study designs and methods for measurement error correction
    D Spiegelman
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Stat Med 24:1657-82. 2005
  7. doi request reprint Approaches to uncertainty in exposure assessment in environmental epidemiology
    Donna Spiegelman
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Annu Rev Public Health 31:149-63. 2010
  8. doi request reprint Commentary: Calculations of EPIC proportions
    Donna Spiegelman
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Int J Epidemiol 37:379-81. 2008
  9. ncbi request reprint Efficient regression calibration for logistic regression in main study/internal validation study designs with an imperfect reference instrument
    D Spiegelman
    Departments of Epidemiology and Biostatistics, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Stat Med 20:139-160. 2001
  10. ncbi request reprint Commentary: Correlated errors and energy adjustment--where are the data?
    Donna Spiegelman
    Departments of Epidemiology and Biostatistics, Harvard School of Public Health, Boston, MA, USA
    Int J Epidemiol 33:1387-8. 2004

Research Grants

  1. MEASUREMENT ERRORS IN CANCER EPIDEMIOLOGY
    Donna Spiegelman; Fiscal Year: 2007
  2. MEASUREMENT ERRORS IN ENVIRONMENTAL EPIDEMIOLOGY
    Donna Spiegelman; Fiscal Year: 2002
  3. MEASUREMENT ERRORS IN ENVIRONMENTAL EPIDEMIOLOGY
    Donna Spiegelman; Fiscal Year: 2009
  4. MEASUREMENT ERRORS IN ENVIRONMENTAL EPIDEMIOLOGY
    DONNA L SPIEGELMAN; Fiscal Year: 2010

Collaborators

Detail Information

Publications68

  1. ncbi request reprint Association between low birth weight and infant mortality in children born to human immunodeficiency virus 1-infected mothers in Tanzania
    Ruilan Wei
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Pediatr Infect Dis J 23:530-5. 2004
    ..The relationship between low birth weight and infant mortality among children born to human immunodeficiency virus (HIV)-infected mothers has not been thoroughly investigated...
  2. ncbi request reprint Point and interval estimates of partial population attributable risks in cohort studies: examples and software
    D Spiegelman
    Department of Epidemiology, School of Public Health, Harvard University, 677 Huntington Avenue, Boston, MA 02115, USA
    Cancer Causes Control 18:571-9. 2007
    ..New England J Med 340 (1999) 1390). A user-friendly SAS macro implementing the methods described in this paper is available via the worldwide web...
  3. pmc Plasma 25-hydroxyvitamin D and risk of breast cancer in the Nurses' Health Study II
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
    Breast Cancer Res 13:R50. 2011
    ..Vitamin D comes from dietary intake and sun exposure and plasma levels of 25-hydroxyvitamin D (25(OH)D) are considered the best measure of vitamin D status...
  4. pmc Gender-related differences in the prevalence of cardiovascular disease risk factors and their correlates in urban Tanzania
    Marina A Njelekela
    Department of Physiology, Muhimbili University of Health and Allied Sciences, PO Box 65001, Dar es Salaam, Tanzania
    BMC Cardiovasc Disord 9:30. 2009
    ..Results of this study will help inform future research and potential preventive and therapeutic interventions against such chronic diseases...
  5. pmc Correcting for bias in relative risk estimates due to exposure measurement error: a case study of occupational exposure to antineoplastics in pharmacists
    D Spiegelman
    Department of Epidemiology, Harvard School of Public Health, Boston, Mass 02115, USA
    Am J Public Health 88:406-12. 1998
    ..This paper describes 2 statistical methods designed to correct for bias from exposure measurement error in point and interval estimates of relative risk...
  6. ncbi request reprint Correlated errors in biased surrogates: study designs and methods for measurement error correction
    D Spiegelman
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Stat Med 24:1657-82. 2005
    ..The methods are illustrated through application to data from the Nurses' Health Study and Health Professionals' Follow-up Study, and comparisons are made to more restrictive models...
  7. doi request reprint Approaches to uncertainty in exposure assessment in environmental epidemiology
    Donna Spiegelman
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Annu Rev Public Health 31:149-63. 2010
    ..The remainder of this review gives an overview of available methods for doing so. Just as we routinely adjust for confounding, we can and should routinely adjust for measurement error...
  8. doi request reprint Commentary: Calculations of EPIC proportions
    Donna Spiegelman
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Int J Epidemiol 37:379-81. 2008
  9. ncbi request reprint Efficient regression calibration for logistic regression in main study/internal validation study designs with an imperfect reference instrument
    D Spiegelman
    Departments of Epidemiology and Biostatistics, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Stat Med 20:139-160. 2001
    ..In these data, because the validation studies contained less than 200 observations and the events of interest were relatively rare, as is typical, the potential improvements offered by this new estimator were not apparent...
  10. ncbi request reprint Commentary: Correlated errors and energy adjustment--where are the data?
    Donna Spiegelman
    Departments of Epidemiology and Biostatistics, Harvard School of Public Health, Boston, MA, USA
    Int J Epidemiol 33:1387-8. 2004
  11. ncbi request reprint Dietary intake in human immunodeficiency virus-infected adults: a comparison of dietary assessment methods
    Kristy Hendricks
    Department of Family Medicine and Community Health, Tufts University, Boston, MA 02111, USA
    J Am Diet Assoc 105:532-40. 2005
    ..The objective of this study was to compare estimated nutrient intakes from 3-day food records vs Food Frequency Questionnaire (FFQ) in a large cohort of individuals living with human immunodeficiency virus (HIV) infection...
  12. ncbi request reprint Vitamins and carotenoids intake and the risk of basal cell carcinoma of the skin in women (United States)
    Teresa T Fung
    Department of Nutrition, Simmons College, Boston, MA 02115, USA
    Cancer Causes Control 13:221-30. 2002
    ..We examined prospectively intakes of vitamins A. C, and E, folate, and specific carotenoids in relation to the risk of basal cell carcinoma of the skin (BCC) in women...
  13. ncbi request reprint Nutrient intake and body weight in a large HIV cohort that includes women and minorities
    Margo N Woods
    Department of Family Medicine and Community Health, Tufts University School of Medicine, Boston, Mass 02111, USA
    J Am Diet Assoc 102:203-11. 2002
    ..Evaluate the baseline nutrient intake of an HIV positive population that includes significant representation from women and minorities, and determine the relationship between state of disease and nutritional intake...
  14. ncbi request reprint Predictors of bone mineral density in human immunodeficiency virus-1 infected children
    Denise L Jacobson
    Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, Massachusetts, USA
    J Pediatr Gastroenterol Nutr 41:339-46. 2005
    ..To compare bone mineral density (BMD) among human immunodeficiency virus (HIV)-infected children with population norms and to determine predictors of BMD in HIV-infected children...
  15. ncbi request reprint Fruit and vegetable intake and risk of major chronic disease
    Hsin Chia Hung
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    J Natl Cancer Inst 96:1577-84. 2004
    ..We evaluated the relationship between fruit and vegetable intake and the incidence of cardiovascular disease and cancer and of deaths from other causes in two prospective cohorts...
  16. pmc Fruit and vegetable intake in relation to risk of breast cancer in the Black Women's Health Study
    Deborah A Boggs
    Slone Epidemiology Center at Boston University, Boston, Massachusetts 02215, USA
    Am J Epidemiol 172:1268-79. 2010
    ....
  17. pmc Lack of association between dietary protein intake and risk of stroke among middle-aged men
    Sarah Rosner Preis
    Departments of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 91:39-45. 2010
    ..Prospective cohort studies in Japanese populations have shown an inverse association between dietary protein and stroke risk. However, this association has not been examined among any study populations of US men...
  18. ncbi request reprint Fruits, vegetables, and colon cancer risk in a pooled analysis of 14 cohort studies
    Anita Koushik
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    J Natl Cancer Inst 99:1471-83. 2007
    ..Statistical power to examine associations by colon site has been limited in previous studies...
  19. ncbi request reprint Role of cytokines and testosterone in regulating lean body mass and resting energy expenditure in HIV-infected men
    Ronenn Roubenoff
    Department of Community Health, Jean Mayer US Department of Agriculture Human Nutrition Research Center, Tufts University, Boston, Massachusetts 02111, USA
    Am J Physiol Endocrinol Metab 283:E138-45. 2002
    ..Even though weight loss was rare in this cohort of patients treated with highly active antiretroviral therapy, loss of LBM was common and was driven by catabolic cytokines and not by inadequate dietary intake or hypogonadism...
  20. ncbi request reprint Breastfeeding and maternal HIV-1 disease progression and mortality
    Gilda Sedgh
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    AIDS 18:1043-9. 2004
    ..To examine the association between breastfeeding and disease progression among HIV-infected women in Dar es Salaam, Tanzania...
  21. ncbi request reprint Micronutrient levels and HIV disease status in HIV-infected patients on highly active antiretroviral therapy in the Nutrition for Healthy Living cohort
    Clara Y Jones
    Department of Public Health and Family Medicine, Tufts University School of Medicine, 200 Harrison Avenue Posner 4, Boston, MA 02111, USA
    J Acquir Immune Defic Syndr 43:475-82. 2006
    ..Low serum micronutrient levels were common before widespread use of highly active antiretroviral therapy (HAART) and were associated with adverse outcomes. Few data are available on micronutrient levels in subjects taking HAART...
  22. ncbi request reprint Dietary carotenoids and risk of lung cancer in a pooled analysis of seven cohort studies
    Satu Mannisto
    Harvard School of Public Health, Department of Nutrition, Boston, Massachusetts, USA
    Cancer Epidemiol Biomarkers Prev 13:40-8. 2004
    ..Although smoking is the strongest risk factor for lung cancer, greater intake of foods high in beta-cryptoxanthin, such as citrus fruit, may modestly lower the risk...
  23. ncbi request reprint Fruits and vegetables and ovarian cancer risk in a pooled analysis of 12 cohort studies
    Anita Koushik
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 14:2160-7. 2005
    ..Associations for total fruits and vegetables were similar for different histologic types. These results suggest that fruit and vegetable consumption in adulthood has no important association with the risk of ovarian cancer...
  24. doi request reprint Drug use and other risk factors related to lower body mass index among HIV-infected individuals
    Lien A Quach
    Tufts University School of Medicine, Boston, MA 02111, USA
    Drug Alcohol Depend 95:30-6. 2008
    ..BMI was also directly associated with CD4 count and inversely related to age more than 55 years old. HIV-infected cocaine users may be at higher risk of developing malnutrition, suggesting the need for anticipatory nutritional support...
  25. ncbi request reprint Individual carotenoid concentrations in adipose tissue and plasma as biomarkers of dietary intake
    Ahmed El-Sohemy
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 76:172-9. 2002
    ..The ability of adipose tissue carotenoid concentrations to reflect dietary intake in population studies is unknown...
  26. pmc Manganese superoxide dismutase (MnSOD) gene polymorphism, interactions with carotenoid levels and prostate cancer risk
    Bahar Mikhak
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Carcinogenesis 29:2335-40. 2008
    ..On the other hand, some epidemiologic studies suggest that the Ala allele is associated with a higher risk of cancer, including prostate cancer...
  27. ncbi request reprint Comparison of bioelectrical impedance and BMI in predicting obesity-related medical conditions
    Kamali Willett
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Obesity (Silver Spring) 14:480-90. 2006
    ..To determine the relative validity of specific bioelectrical impedance analysis (BIA) prediction equations and BMI as predictors of physiologically relevant general adiposity...
  28. ncbi request reprint Incidence of metabolic syndrome in a cohort of HIV-infected adults and prevalence relative to the US population (National Health and Nutrition Examination Survey)
    Denise L Jacobson
    Department of Public Health and Family Medicine, Tufts University School of Medicine, 136 Harrison Avenue Posner 4, Boston, MA 02111, USA
    J Acquir Immune Defic Syndr 43:458-66. 2006
    ..Metabolic syndrome increases the risk of cardiovascular outcomes and type II diabetes. Most of the metabolic abnormalities defining metabolic syndrome are observed in HIV...
  29. pmc Prenatal and early life factors and risk of Parkinson's disease
    Hannah Gardener
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Mov Disord 25:1560-7. 2010
    ..Left-handedness was associated with a 62% increased risk of PD in women but not in men. Further investigation of the relation between prenatal, perinatal, or neonatal factors and PD in other study populations is suggested...
  30. ncbi request reprint Weight loss and survival in HIV-positive patients in the era of highly active antiretroviral therapy
    Alice M Tang
    Department of Family Medicine and Community Health, Tufts University School of Medicine, Boston, MA 02111, USA
    J Acquir Immune Defic Syndr 31:230-6. 2002
    ..In addition, FFM or BCM estimated using bioelectrical impedance analysis does not add further prognostic value over weight loss...
  31. ncbi request reprint Prospective study of the association of changes in dietary intake, physical activity, alcohol consumption, and smoking with 9-y gain in waist circumference among 16 587 US men
    Pauline Koh-Banerjee
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 78:719-27. 2003
    ..Although it is known that abdominal obesity increases the risk of chronic diseases, prospective data examining the relation between lifestyle factors and the accumulation of abdominal adipose tissue are sparse...
  32. ncbi request reprint Alcohol consumption and risk for coronary heart disease among men with hypertension
    Joline W J Beulens
    Harvard School of Public Health, and Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Ann Intern Med 146:10-9. 2007
    ..However, data on the association between alcohol consumption and CVD among individuals with hypertension are scarce...
  33. ncbi request reprint Milk consumption and acne in adolescent girls
    Clement A Adebamowo
    Department of Nutrition, Harvard School of Public Health, Boston, USA
    Dermatol Online J 12:1. 2006
    ..We found a positive association between intake of milk and acne. This finding supports earlier studies and suggests that the metabolic effects of milk are sufficient to elicit biological responses in consumers...
  34. pmc DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer
    Katsuhiko Nosho
    Department of Medical Oncology, Dana Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts, USA
    Clin Cancer Res 15:3663-71. 2009
    ..We hypothesized that cellular DNMT3B level might influence the occurrence of widespread CpG island methylation (i.e., the CpG island methylator phenotype, CIMP) in colon cancer...
  35. ncbi request reprint Dietary and adipose tissue gamma-tocopherol and risk of myocardial infarction
    Ahmed El-Sohemy
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Epidemiology 13:216-23. 2002
    ..Gamma-tocopherol, the most abundant form of dietary vitamin E, may lower the risk of coronary heart disease...
  36. ncbi request reprint Understanding the role of HIV load in determining weight change in the era of highly active antiretroviral therapy
    D Mkaya Mwamburi
    Division of Geographic Medicine and Infectious Diseases, Tufts New England Medical Center, Boston, MA 02111, USA
    Clin Infect Dis 40:167-73. 2005
    ..In this prospective cohort study, we determined the relationship between human immunodeficiency virus (HIV) RNA load and body weight in patients with HIV infection...
  37. pmc Incident depression symptoms are associated with poorer HAART adherence: a longitudinal analysis from the Nutrition for Healthy Living study
    Deborah Kacanek
    Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA
    J Acquir Immune Defic Syndr 53:266-72. 2010
    ..To determine the relationship between incident depression symptoms and suboptimal adherence to HIV highly active antiretroviral therapy (HAART)...
  38. pmc Influence of body size and body fat distribution on risk of uterine leiomyomata in U.S. black women
    Lauren A Wise
    Department of Epidemiology, Harvard School of Public Health, 1010 Commonwealth Avenue, Boston, MA 02215, USA
    Epidemiology 16:346-54. 2005
    ..We prospectively investigated the risk of self-reported uterine leiomyomata in relation to body mass index (BMI), weight change, height, waist and hip circumferences, and waist-to-hip ratio in a large cohort of U.S black women...
  39. ncbi request reprint Vitamin and carotenoid intake and risk of squamous cell carcinoma of the skin
    Teresa T Fung
    Department of Nutrition, Harvard School of Public Health, Boston, MA, USA
    Int J Cancer 103:110-5. 2003
    ..No evidence was found that vitamins A, C and E; folate; or carotenoids play an important protective role against incident SCC...
  40. ncbi request reprint Factors influencing serum cystatin C levels other than renal function and the impact on renal function measurement
    Eric L Knight
    Channing Laboratory, Renal Division, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Kidney Int 65:1416-21. 2004
    ....
  41. pmc Dietary protein and risk of ischemic heart disease in middle-aged men
    Sarah Rosner Preis
    Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 92:1265-72. 2010
    ..Prospective studies in US women have suggested an inverse relation between dietary protein and risk of ischemic heart disease (IHD). However, no large-scale prospective studies have been conducted in US men...
  42. ncbi request reprint Fruits, vegetables and lung cancer: a pooled analysis of cohort studies
    Stephanie A Smith-Warner
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Int J Cancer 107:1001-11. 2003
    ..However, we cannot rule out the possibility that our results are due to residual confounding by smoking. The primary focus for reducing lung cancer incidence should continue to be smoking prevention and cessation...
  43. pmc Aspirin intake and survival after breast cancer
    Michelle D Holmes
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 28:1467-72. 2010
    ..Animal and in vitro studies suggest that aspirin may inhibit breast cancer metastasis. We studied whether aspirin use among women with breast cancer decreased their risk of death from breast cancer...
  44. pmc A prospective study of dietary fat consumption and endometriosis risk
    Stacey A Missmer
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115 5804, USA
    Hum Reprod 25:1528-35. 2010
    ..Fish oil consumption has been associated with symptom improvement in studies of women with primary dysmenorrhea and with decreased endometriosis risk in autotransplantation animal studies...
  45. pmc Total antioxidant capacity intake and colorectal cancer risk in the Health Professionals Follow-up Study
    Rania A Mekary
    Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Bldg 2, Rm 355A, Boston, MA 02115, USA
    Cancer Causes Control 21:1315-21. 2010
    ..To examine the association between total antioxidant capacity (TAC) intake and colorectal cancer incidence...
  46. pmc A randomized trial to determine the optimal dosage of multivitamin supplements to reduce adverse pregnancy outcomes among HIV-infected women in Tanzania
    Kosuke Kawai
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Am J Clin Nutr 91:391-7. 2010
    ..The minimum dosage of multivitamins necessary for optimal benefits is unknown...
  47. pmc Vitamin D status of HIV-infected women and its association with HIV disease progression, anemia, and mortality
    Saurabh Mehta
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS ONE 5:e8770. 2010
    ....
  48. pmc Fat, protein, and meat consumption and renal cell cancer risk: a pooled analysis of 13 prospective studies
    Jung Eun Lee
    Channing Laboratory, Brigham and Women s Hospital, and Harvard Medical School, Boston, MA 02115, USA
    J Natl Cancer Inst 100:1695-706. 2008
    ....
  49. pmc Primary prevention of stroke by healthy lifestyle
    Stephanie E Chiuve
    Harvard School of Public Health, Department of Nutrition, 665 Huntington Ave, Boston, MA 02115, USA
    Circulation 118:947-54. 2008
    ..The combination of healthy lifestyle factors is associated with lower risk of coronary heart disease, diabetes, and total cardiovascular disease. Little is known about the impact of multiple lifestyle factors on the risk of stroke...
  50. pmc Whole grain, bran, and germ intake and risk of type 2 diabetes: a prospective cohort study and systematic review
    Jeroen S L de Munter
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, United States of America
    PLoS Med 4:e261. 2007
    ..We evaluated intakes of whole grain, bran, and germ in relation to risk of type 2 diabetes in prospective cohort studies...
  51. ncbi request reprint Effect of multivitamin and vitamin A supplements on weight gain during pregnancy among HIV-1-infected women
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 76:1082-90. 2002
    ..Multivitamin supplementation was shown to be effective in preventing adverse pregnancy outcomes among HIV-positive women. These protective effects could be mediated in part by an improvement in the pattern of gestational weight gain...
  52. ncbi request reprint Mercury and the risk of coronary heart disease in men
    Kazuko Yoshizawa
    Department of Nutrition, Harvard School of Public Health, Boston, USA
    N Engl J Med 347:1755-60. 2002
    ..A high dietary intake of mercury from consumption of fish has been hypothesized to increase the risk of coronary heart disease...
  53. ncbi request reprint Premenopausal fat intake and risk of breast cancer
    Eunyoung Cho
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02115, USA
    J Natl Cancer Inst 95:1079-85. 2003
    ..We conducted a prospective analysis of the relation between dietary fat intake and breast cancer risk among premenopausal women enrolled in the Nurses' Health Study II...
  54. ncbi request reprint Premenopausal intakes of vitamins A, C, and E, folate, and carotenoids, and risk of breast cancer
    Eunyoung Cho
    Channing Laboratory, Department of Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 12:713-20. 2003
    ..We found no evidence that higher intakes of vitamins C and E, and folate in early adult life reduce risk of breast cancer. However, intake of vitamin A may be related to a reduced risk of breast cancer among smokers...
  55. ncbi request reprint Joint association of alcohol and folate intake with risk of major chronic disease in women
    Rui Jiang
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 158:760-71. 2003
    ..Adequate folate intake may be important in the primary prevention of overall major chronic disease in women, especially among younger women consuming more than two alcoholic drinks per day...
  56. ncbi request reprint Early life menstrual characteristics and pregnancy experiences among women with and without major depression: the Harvard study of moods and cycles
    Bernard L Harlow
    Obstetrics and Gynecology Epidemiology Center at Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    J Affect Disord 79:167-76. 2004
    ..Other than premenstrual dysphoria, few studies have examined the extent to which basic characteristics of the menstrual cycle and the occurrence of other reproductive landmarks impact on the risk of major depression...
  57. ncbi request reprint Diet and risk of ischemic heart disease in India
    Tanuja Rastogi
    Department of Nutrition, Harvard School of Public Health, Boston, USA
    Am J Clin Nutr 79:582-92. 2004
    ..Ischemic heart disease (IHD) is a leading cause of death in India. Dietary changes could reduce risk, but few studies have addressed the association between diet and IHD risk in India...
  58. pmc Common ataxia telangiectasia mutated haplotypes and risk of breast cancer: a nested case-control study
    Rulla M Tamimi
    Program in Molecular and Genetic Epidemiology, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Breast Cancer Res 6:R416-22. 2004
    ..Five biallelic haplotype tagging single nucleotide polymorphisms are estimated to capture 99% of the haplotype diversity in Caucasian populations...
  59. ncbi request reprint A randomized trial of multivitamin supplements and HIV disease progression and mortality
    Wafaie W Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 351:23-32. 2004
    ..Results from observational studies suggest that micronutrient status is a determinant of the progression of human immunodeficiency virus (HIV) disease...
  60. ncbi request reprint Selenium status is associated with accelerated HIV disease progression among HIV-1-infected pregnant women in Tanzania
    Roland Kupka
    Department of Nutrition, Harvard School of Public Health, Boston MA, USA
    J Nutr 134:2556-60. 2004
    ..Selenium status may be important for clinical outcomes related to HIV disease in sub-Saharan Africa...
  61. ncbi request reprint Randomized trial of vitamin supplements in relation to transmission of HIV-1 through breastfeeding and early child mortality
    Wafaie W Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    AIDS 16:1935-44. 2002
    ..HIV-1 transmission through breastfeeding is a global problem and has been associated with poor maternal micronutrient status...
  62. ncbi request reprint Insulin resistance in HIV-infected men and women in the nutrition for healthy living cohort
    Clara Y Jones
    Division of Nutrition and Infectious Disease, Department of Public Health and Family Medicine, Tufts University School of Medicine, Boston, MA 02111, USA
    J Acquir Immune Defic Syndr 40:202-11. 2005
    ..We evaluated insulin resistance (IR) in an HIV-infected cohort and compared our results with those of the National Health and Nutrition Examination Survey III (NHANES III)...
  63. ncbi request reprint Reproducibility of plasma steroid hormones, prolactin, and insulin-like growth factor levels among premenopausal women over a 2- to 3-year period
    Stacey A Missmer
    Channing Laboratory, Brigham and Women s Hospital, 181 Longwood Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 15:972-8. 2006
    ..For estrone and estradiol, where ICCs were relatively low, it is important to use reproducibility data such as those to correct for measurement error in epidemiologic studies...
  64. ncbi request reprint Intake of the major carotenoids and the risk of epithelial ovarian cancer in a pooled analysis of 10 cohort studies
    Anita Koushik
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Int J Cancer 119:2148-54. 2006
    ..These results suggest that consumption of the major carotenoids during adulthood does not play a major role in the incidence of ovarian cancer...
  65. ncbi request reprint Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women
    A Heather Eliassen
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Ave, Boston, MA 02115, USA
    J Natl Cancer Inst 98:1406-15. 2006
    ..We prospectively evaluated associations between plasma sex hormone levels and breast cancer risk among premenopausal women in a case-control study nested within the Nurses' Health Study II...
  66. ncbi request reprint Childhood social environment and Hodgkin's lymphoma: new findings from a population-based case-control study
    Ellen T Chang
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 13:1361-70. 2004
    ..This study examines the current role of childhood social environment in the development of Hodgkin's lymphoma...
  67. ncbi request reprint Multivitamin supplementation improves hematologic status in HIV-infected women and their children in Tanzania
    Wafaie W Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Clin Nutr 85:1335-43. 2007
    ..Anemia is a frequent complication among HIV-infected persons and is associated with faster disease progression and mortality...
  68. ncbi request reprint Vitamin A supplements ameliorate the adverse effect of HIV-1, malaria, and diarrheal infections on child growth
    Eduardo Villamor
    Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
    Pediatrics 109:E6. 2002
    ..We hypothesize that vitamin A supplementation could ameliorate the adverse effect of these infections on child growth...

Research Grants8

  1. MEASUREMENT ERRORS IN CANCER EPIDEMIOLOGY
    Donna Spiegelman; Fiscal Year: 2007
    ..User-friendly, public use software development will be a focus of all new methods development. ..
  2. MEASUREMENT ERRORS IN ENVIRONMENTAL EPIDEMIOLOGY
    Donna Spiegelman; Fiscal Year: 2002
    ..The Berkson measurement error model will be considered, and missing data methodology will be incorporated when relevant. ..
  3. MEASUREMENT ERRORS IN ENVIRONMENTAL EPIDEMIOLOGY
    Donna Spiegelman; Fiscal Year: 2009
    ....
  4. MEASUREMENT ERRORS IN ENVIRONMENTAL EPIDEMIOLOGY
    DONNA L SPIEGELMAN; Fiscal Year: 2010
    ....