Myron Spector

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Effects of cross-linking type II collagen-GAG scaffolds on chondrogenesis in vitro: dynamic pore reduction promotes cartilage formation
    Scott M Vickers
    Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    Tissue Eng 12:1345-55. 2006
  2. ncbi request reprint Novel cell-scaffold interactions encountered in tissue engineering: contractile behavior of musculoskeletal connective tissue cells
    M Spector
    Department of Orthopedic Surgery, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Tissue Eng 8:351-7. 2002
  3. ncbi request reprint Biomaterials-based tissue engineering and regenerative medicine solutions to musculoskeletal problems
    Myron Spector
    Tissue Engineering, VA Boston Healthcare System, and Orthopaedic Research Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Swiss Med Wkly 136:293-301. 2006
  4. doi request reprint The presence and distribution of lubricin in the caprine intervertebral disc
    Kristy M Shine
    Tissue Engineering, VA Boston Healthcare System, 150 South Huntington Avenue, MS 151, Boston, Massachusetts 02130, USA
    J Orthop Res 26:1398-406. 2008
  5. ncbi request reprint Musculoskeletal connective tissue cells with muscle: expression of muscle actin in and contraction of fibroblasts, chondrocytes, and osteoblasts
    M Spector
    Department of Orthopaedic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Wound Repair Regen 9:11-8. 2001
  6. doi request reprint Basement membrane molecule expression attendant to chondrogenesis by nucleus pulposus cells and mesenchymal stem cells
    Wei Seong Toh
    Tissue Engineering, VA Boston Healthcare System, 150 South Huntington Avenue, MS 151, Boston, Massachusetts 02130, USA
    J Orthop Res 31:1136-43. 2013
  7. doi request reprint Lubricin and smooth muscle α-actin-containing myofibroblasts in the pseudomembranes around loose hip and knee prostheses
    Thomas Cheriyan
    VA Boston Healthcare Systems, Boston, MA 02130, USA
    Acta Biomater 9:5751-8. 2013
  8. doi request reprint Modulation of mesenchymal stem cell chondrogenesis in a tunable hyaluronic acid hydrogel microenvironment
    Wei Seong Toh
    Tissue Engineering, VA Boston Healthcare System, Boston, MA 02130, USA
    Biomaterials 33:3835-45. 2012
  9. pmc Engineering endostatin-producing cartilaginous constructs for cartilage repair using nonviral transfection of chondrocyte-seeded and mesenchymal-stem-cell-seeded collagen scaffolds
    Lily Jeng
    Tissue Engineering Laboratories, VA Boston Healthcare System, Boston, Massachusetts 02130, USA
    Tissue Eng Part A 16:3011-21. 2010
  10. doi request reprint Chondrogenic differentiation and lubricin expression of caprine infraspinatus tendon cells
    Tadanao Funakoshi
    Tissue Engineering, VA Boston Healthcare System, Boston, Massachusetts 02130, USA
    J Orthop Res 28:716-25. 2010

Collaborators

Detail Information

Publications55

  1. ncbi request reprint Effects of cross-linking type II collagen-GAG scaffolds on chondrogenesis in vitro: dynamic pore reduction promotes cartilage formation
    Scott M Vickers
    Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    Tissue Eng 12:1345-55. 2006
    ..This approach may provide a useful alternative to traditional means of increasing cell number density and retention of synthesized molecules that promote cartilage formation in tissue-engineered constructs...
  2. ncbi request reprint Novel cell-scaffold interactions encountered in tissue engineering: contractile behavior of musculoskeletal connective tissue cells
    M Spector
    Department of Orthopedic Surgery, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Tissue Eng 8:351-7. 2002
    ....
  3. ncbi request reprint Biomaterials-based tissue engineering and regenerative medicine solutions to musculoskeletal problems
    Myron Spector
    Tissue Engineering, VA Boston Healthcare System, and Orthopaedic Research Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Swiss Med Wkly 136:293-301. 2006
    ....
  4. doi request reprint The presence and distribution of lubricin in the caprine intervertebral disc
    Kristy M Shine
    Tissue Engineering, VA Boston Healthcare System, 150 South Huntington Avenue, MS 151, Boston, Massachusetts 02130, USA
    J Orthop Res 26:1398-406. 2008
    ..Cells from both the annulus and nucleus were found capable of synthesizing lubricin in vitro, suggesting that these cells may be a potential source of the glycoprotein under some conditions...
  5. ncbi request reprint Musculoskeletal connective tissue cells with muscle: expression of muscle actin in and contraction of fibroblasts, chondrocytes, and osteoblasts
    M Spector
    Department of Orthopaedic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Wound Repair Regen 9:11-8. 2001
    ....
  6. doi request reprint Basement membrane molecule expression attendant to chondrogenesis by nucleus pulposus cells and mesenchymal stem cells
    Wei Seong Toh
    Tissue Engineering, VA Boston Healthcare System, 150 South Huntington Avenue, MS 151, Boston, Massachusetts 02130, USA
    J Orthop Res 31:1136-43. 2013
    ..These results inform the use of MSCs for NP regeneration and suggest the possible involvement of certain BM molecules in chondrogenesis and cartilage regeneration...
  7. doi request reprint Lubricin and smooth muscle α-actin-containing myofibroblasts in the pseudomembranes around loose hip and knee prostheses
    Thomas Cheriyan
    VA Boston Healthcare Systems, Boston, MA 02130, USA
    Acta Biomater 9:5751-8. 2013
    ..There was a significant effect of location on the number of SMA-expressing cells, but not of implant type. These findings might explain why the management of loose prosthesis is so challenging...
  8. doi request reprint Modulation of mesenchymal stem cell chondrogenesis in a tunable hyaluronic acid hydrogel microenvironment
    Wei Seong Toh
    Tissue Engineering, VA Boston Healthcare System, Boston, MA 02130, USA
    Biomaterials 33:3835-45. 2012
    ....
  9. pmc Engineering endostatin-producing cartilaginous constructs for cartilage repair using nonviral transfection of chondrocyte-seeded and mesenchymal-stem-cell-seeded collagen scaffolds
    Lily Jeng
    Tissue Engineering Laboratories, VA Boston Healthcare System, Boston, Massachusetts 02130, USA
    Tissue Eng Part A 16:3011-21. 2010
    ..The ability to engineer endostatin-expressing cartilaginous constructs will be of value for future work exercising regulatory control of angiogenesis in cartilage repair...
  10. doi request reprint Chondrogenic differentiation and lubricin expression of caprine infraspinatus tendon cells
    Tadanao Funakoshi
    Tissue Engineering, VA Boston Healthcare System, Boston, Massachusetts 02130, USA
    J Orthop Res 28:716-25. 2010
    ..These data inform the use of tendon cells for rotator cuff repair, including for fibrocartilaginous zones...
  11. doi request reprint alpha-Smooth muscle actin-expressing cells and lubricin in periprosthetic tissue
    Tadanao Funakoshi
    Department of Orthopaedic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biomed Mater Res A 93:515-27. 2010
    ....
  12. ncbi request reprint Cartilaginous deposits in subchondral bone in regions of exposed bone in osteoarthritis of the human knee: histomorphometric study of PRG4 distribution in osteoarthritic cartilage
    Dong Zhang
    Tissue Engineering, VA Boston Healthcare System, Orthopaedic Research Laboratory, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02130, USA
    J Orthop Res 25:873-83. 2007
    ..These cells may be able to contribute to the resurfacing of the joint in certain cartilage repair procedures...
  13. ncbi request reprint Plasmid size influences chitosan nanoparticle mediated gene transfer to chondrocytes
    Ximing Xu
    Tissue Engineering, VA Boston Healthcare System, Boston, Massachusetts 02130, USA
    J Biomed Mater Res A 84:1038-48. 2008
    ..These results indicate that although a large plasmid can be successfully incorporated within chitosan nanoparticles, the size of the plasmid incorporated within the nanoparticles may still significantly affect gene transfer to cells...
  14. doi request reprint Lubricin in human breast tissue expander capsules
    Thomas Cheriyan
    VA Boston Healthcare Systems, Boston, Massachusetts 02130, USA
    J Biomed Mater Res B Appl Biomater 100:1961-9. 2012
    ..Varying degrees of synovial metaplasia were seen at the tissue-implant interface. α-SMA-containing cells were also seen in all but one patient. The findings might help us better understand factors involved in capsule formation...
  15. doi request reprint Viscoelastic characterization of rat cerebral cortex and type I collagen scaffolds for central nervous system tissue engineering
    Paul Z Elias
    Tissue Engineering Laboratories, VA Boston Healthcare System, 150 South Huntington Ave, Boston, MA 02130, USA
    J Mech Behav Biomed Mater 12:63-73. 2012
    ..Similarities and differences between the mechanical behavior of the brain and collagen scaffolds of varying collagen concentration are discussed in relation to application of biomaterials for regenerative medicine...
  16. doi request reprint Engineering endostatin-expressing cartilaginous constructs using injectable biopolymer hydrogels
    Lily Jeng
    Tissue Engineering, VA Boston Healthcare System, Boston, MA 02130, USA
    Acta Biomater 8:2203-12. 2012
    ....
  17. doi request reprint Extracorporeal shockwave-induced expression of lubricin in tendons and septa
    Dafang Zhang
    Harvard Medical School, Boston, MA 02115, USA
    Cell Tissue Res 346:255-62. 2011
    ..Increased lubricin expression may contribute to the beneficial effects of ESWT in providing pain and symptom relief in musculoskeletal disorders by decreasing erosive wear...
  18. doi request reprint Non-viral endostatin plasmid transfection of mesenchymal stem cells via collagen scaffolds
    Xiao Dan Sun
    Tissue Engineering, VA Boston Healthcare System, Mail Stop 151 Research, 150 S Huntington Ave, Boston, MA 02130, USA
    Biomaterials 30:1222-31. 2009
    ..The results demonstrate the promise of the non-viral delivery of the gene for this potent anti-angiogenic protein to MSCs via a collagen scaffold...
  19. doi request reprint Lubricin distribution in the torn human anterior cruciate ligament and meniscus
    Dafang Zhang
    Harvard Medical School, Boston, Massachusetts 02115, USA
    J Orthop Res 29:1916-22. 2011
    ..In all tissues, lubricin was found in the matrix and intracellularly. The surface layer of lubricin coating torn edges of ACLs and menisci may interfere with the integrative healing process needed for repair...
  20. doi request reprint Chemotactic recruitment of adult neural progenitor cells into multifunctional hydrogels providing sustained SDF-1α release and compatible structural support
    Teck Chuan Lim
    Tissue Engineering Laboratories, VA Boston Healthcare System, Mail Stop 151 Research, 150 S Huntington Ave, Boston, MA 02130, USA
    FASEB J 27:1023-33. 2013
    ..Overall, Gtn-HPA/SDF-1α-PCN hydrogels prove to be promising biomaterials for injection into cavitary brain lesions to recruit endogenous NPCs and enhance neural tissue repair/regeneration...
  21. ncbi request reprint Contractile forces generated by articular chondrocytes in collagen-glycosaminoglycan matrices
    Janice M Zaleskas
    Department of Orthopaedic Surgery, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Biomaterials 25:1299-308. 2004
    ..Adult articular chondrocytes are capable of generating a SMA-enabled force of contraction sufficient to model extracellular matrix molecules...
  22. pmc Distribution of lubricin in the ruptured human rotator cuff and biceps tendon: a pilot study
    Tadanao Funakoshi
    Department of Orthopaedic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Clin Orthop Relat Res 468:1588-99. 2010
    ..Lubricin is a lubricant for diarthrodial joint tissues and has antiadhesion properties; its presence in the (caprine) rotator cuff suggests it may have a role in intrafascicular lubrication...
  23. doi request reprint Astrocyte infiltration into injectable collagen-based hydrogels containing FGF-2 to treat spinal cord injury
    Daniel J Macaya
    Tissue Engineering, VA Boston Healthcare System, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02130, USA
    Biomaterials 34:3591-602. 2013
    ..Overall, injectable collagen-genipin hydrogels containing FGF-2-containing LMTs are a promising candidate for the treatment for SCI through the attraction of astrocytes into the graft...
  24. pmc Presence and distribution of the lubricating protein, lubricin, in the meibomian gland in rabbits
    Thomas Cheriyan
    Tissue Engineering, VA Boston Healthcare System, Boston, MA 02130, USA
    Mol Vis 17:3055-61. 2011
    ..This study investigates the presence of lubricin in the meibomian gland, lacrimal gland and ocular surface of healthy rabbits; prompted by the hypothesis that lubricin acts as boundary lubricant and anti-adhesive protein in the eye...
  25. doi request reprint Lubricin distribution in the human intervertebral disc
    Kristy M Shine
    Tissue Engineering, VA Boston Healthcare System, Boston, MA 02130, USA
    J Bone Joint Surg Am 91:2205-12. 2009
    ..In this immunohistochemical study, we determined the presence and distribution of lubricin in the cells, extracellular matrix, and tissue surfaces of human nucleus pulposus and anulus fibrosus tissues...
  26. doi request reprint Biomaterial-mediated delivery of microenvironmental cues for repair and regeneration of articular cartilage
    Wei Seong Toh
    Tissue Engineering Laboratories, VA Boston Healthcare System, MS 151, Boston, Massachusetts 02130, USA
    Mol Pharm 8:994-1001. 2011
    ..The latest advances in cartilage tissue engineering and regeneration are critically reviewed to demonstrate an outline of challenges toward biomaterial-based approaches of cartilage regeneration...
  27. ncbi request reprint Alpha-smooth muscle actin in pathological human disc nucleus pulposus cells in vivo and in vitro
    Dawn Hastreiter
    Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Wound Repair Regen 12:430-8. 2004
    ..008), with values decreasing through 4 weeks and then slightly rising at 6 weeks. The role of alpha-SMA in intervertebral disc pathology warrants further investigation...
  28. ncbi request reprint Delivery of plasmid IGF-1 to chondrocytes via cationized gelatin nanoparticles
    Ximing Xu
    Tissue Engineering, VA Boston Healthcare System, Boston, Massachusetts 02130, USA
    J Biomed Mater Res A 84:73-83. 2008
    ..A peak in the amount of released IGF-1 was detected at a gelatin:IGF-1 weight ratio of 250:1...
  29. doi request reprint Development of hyaluronic acid-based scaffolds for brain tissue engineering
    Tzu Wei Wang
    Tissue Engineering Laboratories, VA Boston Healthcare System, Mail Stop 151 Research, 150 S Huntington Ave, Boston, MA 02130, USA
    Acta Biomater 5:2371-84. 2009
    ....
  30. pmc Tissue-Engineered Cartilaginous Constructs for the Treatment of Caprine Cartilage Defects, Including Distribution of Laminin and Type IV Collagen
    Lily Jeng
    1 Tissue Engineering, VA Boston Healthcare System, Boston, Massachusetts
    Tissue Eng Part A 19:2267-74. 2013
    ..Future work is needed to elucidate the role of basement membrane molecules during cartilage repair and regeneration. ..
  31. doi request reprint Lubricin distribution in the goat infraspinatus tendon: a basis for interfascicular lubrication
    Tadanao Funakoshi
    Tissue Engineering, VA Boston Healthcare System, 150 South Huntington Avenue, MS 151, Boston, MA 02130, USA
    J Bone Joint Surg Am 90:803-14. 2008
    ..The hypothesis was that lubricin, also known as superficial zone protein or proteoglycan 4, serves as an interfascicular lubricant...
  32. ncbi request reprint Genetically enhanced engineering of meniscus tissue using ex vivo delivery of transforming growth factor-beta 1 complementary deoxyribonucleic acid
    Andre F Steinert
    Center for Molecular Orthopedics, Department of Orthopedic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Tissue Eng 13:2227-37. 2007
    ..These results indicate that TGF-beta1 cDNA delivery may affect cell-based meniscus repair approaches in vivo...
  33. doi request reprint Clinical application of extracorporeal shock wave therapy in orthopedics: focused versus unfocused shock waves
    Casper Bindzus Foldager
    Department of Orthopedics, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Ultrasound Med Biol 38:1673-80. 2012
    ..The aim of the present review is to investigate differences in outcome in select orthopaedic applications using focused and unfocused shock waves...
  34. ncbi request reprint Treatment of penetrating brain injury in a rat model using collagen scaffolds incorporating soluble Nogo receptor
    Paul Z Elias
    Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA Tissue Engineering Laboratories, VA Boston Healthcare System, Boston, MA, USA
    J Tissue Eng Regen Med . 2012
    ..Copyright © 2012 John Wiley & Sons, Ltd...
  35. doi request reprint The use of extracorporeal shock wave-stimulated periosteal cells for orthotopic bone generation
    Cathal J Kearney
    Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, USA
    Tissue Eng Part A 18:1500-8. 2012
    ..These results successfully demonstrated the efficacy of ESW-stimulated periosteum for orthotopic bone generation...
  36. doi request reprint The effect of injectable gelatin-hydroxyphenylpropionic acid hydrogel matrices on the proliferation, migration, differentiation and oxidative stress resistance of adult neural stem cells
    Teck Chuan Lim
    Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Biomaterials 33:3446-55. 2012
    ..Overall, Gtn-HPA hydrogels are promising injectable matrices for supporting and influencing aNSCs in ways that may be beneficial for brain tissue regeneration after injuries...
  37. doi request reprint The reparative response to cross-linked collagen-based scaffolds in a rat spinal cord gap model
    Rahmatullah H Cholas
    Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Biomaterials 33:2050-9. 2012
    ....
  38. ncbi request reprint Early bone apposition in vivo on plasma-sprayed and electrochemically deposited hydroxyapatite coatings on titanium alloy
    Hao Wang
    Department of Materials Science and Engineering, Massachusetts Institute of Technology, 77 Massachusetts Ave, Cambridge, and Tissue Engineering, VA Boston Healthcare System, MA 02139, USA
    Biomaterials 27:4192-203. 2006
    ....
  39. ncbi request reprint Contractile actin expression in torn human menisci
    B Y Lin
    Department of Orthopaedic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Wound Repair Regen 10:259-66. 2002
    ..This underscores the importance of providing a bridging scaffold into which such cells can migrate...
  40. ncbi request reprint Proteoglycans synthesized by canine intervertebral disc cells grown in a type I collagen-glycosaminoglycan matrix
    Yuan Rong
    Department of Orthopedic Suergery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Tissue Eng 8:1037-47. 2002
    ..The results provide a foundation for future investigations of collagen-glycosaminoglycan matrices for intervertebral disc tissue engineering...
  41. ncbi request reprint Composition of joint fluid in patients undergoing total knee replacement and revision arthroplasty: correlation with flow properties
    Dan Mazzucco
    Division of Health Sciences and Technology, Massachusetts Institute of Technology, and Tissue Engineering, VA Boston Healthcare System, USA
    Biomaterials 25:4433-45. 2004
    ..The variation in composition and lower HA concentration in joints necessitating revision may relate to variation in arthroplasty lubrication leading to highly variable wear rates and clinical outcomes...
  42. ncbi request reprint A glimpse of tissue engineering in China
    Zhou Xiang
    Department of Orthopaedic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Tissue Eng 8:169-74. 2002
    ..A brief summary of some of the papers may begin to suggest possibilities for collaboration between tissue engineers inside and outside of China, as well as to facilitate dissemination of important findings...
  43. ncbi request reprint Cell outgrowth from the human ACL in vitro: regional variation and response to TGF-beta1
    Martha Meaney Murray
    Department of Orthopedic Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Orthop Res 20:875-80. 2002
    ..However, this study is only a first step, and additional experiments are needed to further optimize tissue engineering parameters for enhancement of the repair of the ACL...
  44. ncbi request reprint Rheology of joint fluid in total knee arthroplasty patients
    Dan Mazzucco
    Department of Orthopaedic Surgery, Brigham and Women s Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    J Orthop Res 20:1157-63. 2002
    ..Both groups exhibited degenerate flow properties when compared to synovial fluid from healthy individuals. Further examination of the connection between flow properties and the tribology of joint replacement prostheses is warranted...
  45. ncbi request reprint Fabrication and characterization of porous hyaluronic acid-collagen composite scaffolds
    Shunqing Tang
    Department of Biomedical Engineering, Jinan University, Guangzhou 510632, China
    J Biomed Mater Res A 82:323-35. 2007
    ..The demonstration that these scaffolds can be populated by chondrocytes and support in vitro formation of cartilaginous tissue warrants further investigation of this material system for tissue engineering...
  46. ncbi request reprint Bone bonding to hydroxyapatite and titanium surfaces on femoral stems retrieved from human subjects at autopsy
    Alexandra E Porter
    Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge MA 02139, USA
    Biomaterials 25:5199-208. 2004
    ..Many ultrastructural features of the bone bonded to the HA coatings on these implants from human subjects were comparable to those found on HA-coated devices implanted in a canine model...
  47. ncbi request reprint Formation of lung alveolar-like structures in collagen-glycosaminoglycan scaffolds in vitro
    Patty Chen
    Division of Health Sciences and Technology, Harvard Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    Tissue Eng 11:1436-48. 2005
    ..This culture system may be of value in facilitating exploration of strategies for preparing such scaffolds for the regeneration of lung tissue in vivo...
  48. ncbi request reprint Collagen-GAG scaffolds grafted onto myocardial infarcts in a rat model: a delivery vehicle for mesenchymal stem cells
    Zhou Xiang
    Department of Orthopaedic Surgery, Huaxi Hospital, Sichuan University, Chengdu, China
    Tissue Eng 12:2467-78. 2006
    ..BrdU-positive cells appeared both in the degraded scaffold and the infarct region. DHT cross-linked collagen-GAG scaffolds warrant continued investigation as delivery vehicles for implantation of cells into infarcted cardiac tissue...
  49. ncbi request reprint Scaffold-based articular cartilage repair
    Ramille M Capito
    Department of Material Science and Engineering Department, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    IEEE Eng Med Biol Mag 22:42-50. 2003
  50. ncbi request reprint Periosteum stimulates subchondral bone densification in autologous chondrocyte transplantation in a sheep model
    Martin Russlies
    Department of Orthopaedic Surgery, University Hospital Lubeck, 23538 Lubeck, Germany
    Cell Tissue Res 319:133-42. 2005
    ..These findings warrant evaluation of subchondral bone changes in patients treated by ACT and the correlation of these changes with clinical outcome...
  51. ncbi request reprint Quantitation of osteoblast-like cell mineralization on tissue culture polystyrene and Ti-6Al-4V alloy disks by Tc-99m-MDP labeling and imaging in vitro
    Hao Wang
    Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    Bone 36:84-92. 2005
    ..The results warrant implementation of this scintigraphic method for quantitative studies of osteoblast-mediated mineralization in vitro...
  52. ncbi request reprint Biomanufacturing: a US-China National Science Foundation-sponsored workshop
    Wei Sun
    Mechanical Engineering and Mechanics, Drexel University, Philadelphia, Pennsylvania, USA
    Tissue Eng 12:1169-81. 2006
    ..In formulating the questions that remain to be answered and discussing the knowledge required to further advance the field, the Workshop provided a basis for recommendations for future work...
  53. ncbi request reprint Translation from research to applications
    Ernst Hunziker
    ITI Research Institute for Dental and Skeletal Biology, University of Bern, Bern, Switzerland
    Tissue Eng 12:3341-64. 2006
    ..b>Myron Spector discussed collagen-glycosaminoglycan (GAG) scaffolds for musculoskeletal tissue engineering...
  54. ncbi request reprint Collagen-based matrices with axially oriented pores
    Marta Madaghiele
    Department of Engineering for Innovation, University of Lecce, Lecce, 73100 Italy
    J Biomed Mater Res A 85:757-67. 2008
    ..In particular the definition of an orientation index (OI) was employed as a means to quantify the orientation of the pore channels inside the scaffolds...
  55. doi request reprint Incorporation of hyaluronic acid into collagen scaffolds for the control of chondrocyte-mediated contraction and chondrogenesis
    Shunqing Tang
    Department of Biomedical Engineering, Jinan University, Guangzhou 510632, People s Republic of China
    Biomed Mater 2:S135-41. 2007
    ..HA can play a useful role in adjusting the mechanical behavior of tissue engineering scaffolds and chondrogenesis in chondrocyte-seeded scaffolds...