Research Topics
Species | Sulpicio G SorianoSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Levels of soluble adhesion molecules are elevated in the cerebrospinal fluid of children with moyamoya syndromeSulpicio G Soriano
Department of Anesthesia Anesthesia and Critical Care Laboratory, Children s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Neurosurgery 50:544-9. 2002....- Pediatric neuroanesthesiaSulpicio G Soriano
Children s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
Neuroimaging Clin N Am 17:259-67. 2007..The aim of this paper is to highlight these age-dependent approaches to the pediatric neurosurgical patient... - Antiepileptic-induced resistance to neuromuscular blockers: mechanisms and clinical significanceSulpicio G Soriano
Harvard Medical School and Children s Hospital, Boston, Massachusetts 02115, USA
Clin Pharmacokinet 43:71-81. 2004.... - Pediatric neuroanesthesiaSulpicio G Soriano
Children s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
Anesthesiol Clin North America 20:389-404. 2002..A basic understanding of age-dependent variables and the interaction of anesthetic and surgical procedures are essential in minimizing perioperative morbidity and mortality... - Neuroanesthesia. Innovative techniques and monitoringSulpicio G Soriano
Department of Anesthesia, Children s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Anesthesiol Clin North America 20:137-51. 2002..A danger in this process, however, is the potential for public opinion, outside regulatory bodies, or medico-legal implications to drive change and enforce standards of care before appropriate data are available... - Mice deficient in fractalkine are less susceptible to cerebral ischemia-reperfusion injurySulpicio G Soriano
Department of Anesthesia, Children s Hospital, Boston, 300 Longwood Avenue, Boston, MA 02115, USA
J Neuroimmunol 125:59-65. 2002..The findings of this study indicate a possible role for FKN in augmenting postischemic injury and mortality after transient focal cerebral ischemia... - Perioperative management of diabetes insipidus in childrenLisa Wise-Faberowski
Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts, USA
J Neurosurg Anesthesiol 16:220-5. 2004..6 +/- 9.2 mEq/L versus 8.36 +/- 6.43 mEq/L in those children managed by the protocol. Hyponatremia occurred less frequently in the children managed with this protocol compared with historical controls... 
Sevoflurane binds and allosterically blocks integrin lymphocyte function-associated antigen-1Koichi Yuki
Department of Anesthesiology, Perioperative and Pain Medicine, Children s Hospital Boston, and Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts 02115, USA
Anesthesiology 113:600-9. 2010..It remains to be determined whether the allosteric inhibition of LFA-1 by isoflurane can be generalized to other anesthetics such as sevoflurane...- Noxious stimulation attenuates ketamine-induced neuroapoptosis in the developing rat brainJia Ren Liu
Department of Anesthesiology, Perioperative and Pain Medicine, Children s Hospital, Boston, Massachusetts 02115, USA
Anesthesiology 117:64-71. 2012..We hypothesized that concurrent noxious stimulation would attenuate ketamine-induced caspase-3 activation... - Anesthetic concerns for pediatric patients in an intraoperative MRI suiteCraig D McClain
Children s Hospital Boston Harvard Medical School, Boston, Massachusetts 02115, USA
Curr Opin Anaesthesiol 24:480-6. 2011..Failure to recognize the differences between the diagnostic MRI environment and the iMRI environment can compromise the safety of the patient and operating room staff and present logistical problems... - Perioperative management of diabetes insipidus in children [corrected]Lisa Wise-Faberowski
Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts, USA
J Neurosurg Anesthesiol 16:14-9. 2004..6 +/- 9.2 mEq/L versus 8.36 +/- 6.43 mEq/L in those children managed by the protocol. Hyponatremia occurred less frequently in the children managed with this protocol compared with historical controls... - Long-term outcome in children with moyamoya syndrome after cranial revascularization by pial synangiosisR Michael Scott
Department of Neurosurgery, The Children s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
J Neurosurg 100:142-9. 2004..This study was undertaken to determine if a standardized neurosurgical revascularization procedure, pial synangiosis, conferred long-term benefit in pediatric patients... - Efficacy of tranexamic acid in pediatric craniosynostosis surgery: a double-blind, placebo-controlled trialSusan M Goobie
Department of Anesthesia, Perioperative, and Pain Medicine, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
Anesthesiology 114:862-71. 2011..The primary and secondary outcome variables were reduction in perioperative blood loss and reduction in blood transfusion, respectively... - Population pharmacokinetics of tranexamic acid in paediatric patients undergoing craniosynostosis surgerySusan M Goobie
Department of Anesthesia, Perioperative and Pain Medicine, Boston Children s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
Clin Pharmacokinet 52:267-76. 2013..The pharmacokinetics of TXA have not been fully characterized in paediatric patients and dosing regimens remain diverse in practice. A mixed-effects population analysis would characterize patient variability and guide dosing practices... - Endoscopic strip craniectomy in early infancy: the initial five years of anesthesia experiencePetra M Meier
Department of Anesthesiology, Perioperative and Pain Medicine, Children s Hospital Boston, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
Anesth Analg 112:407-14. 2011..The hypothesis was that infants with low body weight and syndromes would have a higher risk of perioperative blood transfusion and that those with respiratory complications are more likely to be admitted to the intensive care unit (ICU)... 
Spinal anesthesia in infant rats: development of a model and assessment of neurologic outcomesBarak Yahalom
Department of Anesthesiology, Perioperative and Pain Medicine, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
Anesthesiology 114:1325-35. 2011..Spinal anesthesia is an alternative to general anesthesia for some infant surgeries. To test for potential toxicity, a spinal anesthesia model in infant rats was developed...- Anesthesia for epilepsy surgery in childrenSulpicio G Soriano
Department of Anesthesiology, Perioperative and Pain Medicine, Children s Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
Childs Nerv Syst 22:834-43. 2006..OBJECTIVE: This review will provide a systematic approach to pediatric patients undergoing epilepsy surgery... - Sedative drug modulates T-cell and lymphocyte function-associated antigen-1 functionKoichi Yuki
Department of Anesthesiology, Pain and Perioperative Medicine, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
Anesth Analg 112:830-8. 2011..In the current study, we examined the effect of propofol, midazolam, and dexmedetomidine on LFA-1/ICAM-1 binding, and the subsequent biological effects... - Let's not throw the baby out with the bath water: potential neurotoxicity of anesthetic drugs in infants and childrenSulpicio G Soriano
Department of Anaesthesia, Harvard Medical School and Children's Hospital, Boston, Massachusetts, USA
J Neurosurg Anesthesiol 17:207-9. 2005 - Clinical research approaches to studying pediatric anesthetic neurotoxicityMary Ellen McCann
Department of Anesthesiology, Perioperative and Pain Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
Neurotoxicology 30:766-71. 2009.... - Anaesthetic management of children with tuberous sclerosisZe ev Shenkman
Department of Anaesthesia, Children s Hospital, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Paediatr Anaesth 12:700-4. 2002..Tuberous sclerosis (TS) is a hamartomatous disease that usually presents with cutaneous and intracranial lesions, but can also affect other organ systems... - Selective anesthesia-induced neuroinflammation in developing mouse brain and cognitive impairmentXia Shen
Geriatric Anesthesia Research Unit, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129 2060, USA
Anesthesiology 118:502-15. 2013..The authors therefore have established an animal model with single versus multiple exposures of anesthetic(s) in young versus adult mice, aiming to distinguish the role of different types of anesthesia in cognitive impairment... - Acute intraoperative neurogenic pulmonary edema during endoscopic ventriculoperitoneal shunt revisionGalina Davidyuk
Department of Anesthesiology, Perioperative and PainMedicine, Childrens Hospital Boston, Harvard Medical School, Boston, Massachussets 02115, USA
Anesth Analg 110:594-5. 2010.... - Detection of unanticipated intracranial hemorrhage during intraoperative magnetic resonance image-guided neurosurgery. Report of two casesCraig D McClain
Department of Anesthesiology, Perioperative and Pain Medicine, Children s Hospital Boston, Massachusetts 02115, USA
J Neurosurg 106:398-400. 2007..These cases illustrate the ability of iMR imaging to aid in differentiating unexpected and/or unexplained intraoperative events in pediatric neurosurgery... - Is anesthesia bad for the newborn brain?Mary Ellen McCann
Department of Anesthesia Pediatrics, Harvard Medical School, Boston, MA, USA
Anesthesiol Clin 27:269-84. 2009..In this article, the authors review the relevant preclinical and clinical data that are currently available on this topic... - An assessment of the effects of general anesthetics on developing brain structure and neurocognitive functionAndreas W Loepke
Department of Anesthesia, Cincinnati Children s Hospital Medical Center, 3333 Burnet Ave, Cincinnati, OH, USA
Anesth Analg 106:1681-707. 2008..In the present review, we assess the evidence for the effects of commonly used anesthetics on neuronal structure and neurocognitive function in newborn humans and animals... - General anesthetics in pediatric anesthesia: influences on the developing brainMary Ellen McCann
Department of Anaesthesia Pediatrics, Harvard Medical School, Senior Associate in Anesthesiology, Children s Hospital Boston, Massachusetts, USA 02115
Curr Drug Targets 13:944-51. 2012..This paper examines the evidence for the effects of commonly used anesthetics on neuronal structure and neurocognitive function in laboratory models and reviews the relevant clinical human epidemiologic data... - The volatile anesthetic isoflurane perturbs conformational activation of integrin LFA-1 by binding to the allosteric regulatory cavityKoichi Yuki
Department of Anaesthesia, Harvard Medical School, 200 Longwood Ave, Rm 253, Boston, MA 02115, USA
FASEB J 22:4109-16. 2008..These results provide a potential mechanism for the immunomodulatory properties of isoflurane... - Detection of intestinal inflammation by MicroPET imaging using a (64)Cu-labeled anti-beta(7) integrin antibodyJason L J Dearling
Division of Nuclear Medicine, Department of Radiology, Children s Hospital, Boston, Massachusetts 02115, USA
Inflamm Bowel Dis 16:1458-66. 2010..The aim of this study was to investigate the possibility of imaging colitis radioimmunodetection by targeting the beta(7) integrin with a radiolabeled antibody... - Ketamine activates cell cycle signaling and apoptosis in the neonatal rat brainSulpicio G Soriano
Department of Anesthesiology, Perioperative and Pain Medicine, Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
Anesthesiology 112:1155-63. 2010..To explore this hypothesis, the authors characterized the effect of ketamine on the cell cycle signaling pathway in the developing rodent brain in vivo and in vitro... - Anesthetic management of pial synangiosis and intracranial hemorrhage with a Fontan circulationBalachundhar Subramaniam
Department of Anesthesiology, Perioperative and Pain Medicine, Children's Hospital Boston, Boston, MA 02115, USA
Paediatr Anaesth 16:72-6. 2006..The case highlights the importance of understanding Fontan physiology and its interrelationship with the cerebral circulation in the setting of cerebrovascular insufficiency and raised intracranial pressure... - Anesthesia and analgesia during and after surgery in neonatesCharles B Berde
Department of Anaesthesia, Children s Hospital, Harvard Medical School, Boston, MA 02115, USA
Clin Ther 27:900-21. 2005..Over the past 20 years, there has been a growing body of research on the clinical pharmacology and clinical outcomes of these agents in neonates and infants... - Prolonged exposure to ketamine increases brain derived neurotrophic factor levels in developing rat brainsJuan C Ibla
Department of Anesthesiology, Perioperative and Pain Medicine, Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
Curr Drug Saf 4:11-6. 2009..The ketamine-treated rat pups had increased neurodegeneration, BDNF and TrkB cDNA products and protein levels. This increased expression of BDNF may be a response to ketamine-induced injury... - Summary proceedings from the neonatal pain-control groupKanwaljeet J S Anand
Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
Pediatrics 117:S9-S22. 2006..Full-length articles on procedural pain, sedation and analgesia for ventilated infants, perioperative pain, and study designs for neonatal pain research were published in Clinical Therapeutics (June 2005)... - Analgesia and anesthesia for neonates: study design and ethical issuesK J S Anand
Department of Pediatrics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, USA
Clin Ther 27:814-43. 2005.... - Of mice and men: should we extrapolate rodent experimental data to the care of human neonates?Sulpicio G Soriano
Anesthesiology 102:866-8; author reply 868-9. 2005 - Society of Neurosurgical Anesthesia and Critical Care (SNACC) newsletter: report of the 2002 annual meeting, Orlando, FloridaMary Ann Cheng
Department of Anesthesiology, Washington University School of Medicine, St Louis, Missouri, USA
J Neurosurg Anesthesiol 15:165-7. 2003 - Repeated administration of ketamine may lead to neuronal degeneration in the developing rat brainHideaki Hayashi
Department of Anesthesia, Kansai Rosai Hospital, Japan
Paediatr Anaesth 12:770-4. 2002..CONCLUSIONS: These findings suggest that the duration of ketamine exposure correlates with increased neuronal degeneration in the developing rat brain... - Lidocaine pretreatment for the prevention of propofol-induced transient motor disturbances in children during anesthesia induction: a randomized controlled trial in children undergoing invasive hematologic proceduresFederico Bilotta
Department of Anesthesiology, Intensive Care and Pain Medicine, University of Rome La Sapienza, Rome, Italy
Paediatr Anaesth 16:1232-7. 2006.... - CON: The toxic effects of anesthetics in the developing brain: the clinical perspectiveAndreas W Loepke
Anesth Analg 106:1664-9. 2008