Research Topics
Genomes and Genes
| Yiqing SongSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Associations of dietary flavonoids with risk of type 2 diabetes, and markers of insulin resistance and systemic inflammation in women: a prospective study and cross-sectional analysisYiqing Song
Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02215, USA
J Am Coll Nutr 24:376-84. 2005..The aim of the present study was to examine the association of dietary flavonol and flavone intake with type 2 diabetes, and biomarkers of insulin resistance and systemic inflammation...
Effects of oral magnesium supplementation on glycaemic control in Type 2 diabetes: a meta-analysis of randomized double-blind controlled trialsY Song
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Diabet Med 23:1050-6. 2006..The aim of this study was to assess the evidence on the effect of oral magnesium supplementation on glycaemic control in patients with Type 2 diabetes...
Dietary magnesium intake and risk of cardiovascular disease among womenYiqing Song
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 96:1135-41. 2005..In conclusion, the results do not support the hypothesis that magnesium intake reduces the development of CHD, although a modest inverse association with stroke cannot be ruled out...
Magnesium intake, C-reactive protein, and the prevalence of metabolic syndrome in middle-aged and older U.S. womenYiqing Song
Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
Diabetes Care 28:1438-44. 2005..The aim of this study was to examine whether and to what extent magnesium intake is related to systemic inflammation and the metabolic syndrome...
FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal womenYiqing Song
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Obesity (Silver Spring) 16:2472-80. 2008..In conclusion, common genetic variants in the intron 1 of FTO gene may confer a modest susceptibility to obesity in an ethnicity-specific manner, but may be unlikely to contribute to a clinically significant diabetes risk...
Sex hormone-binding globulin and risk of type 2 diabetes in women and menEric L Ding
Department of Nutrition, Harvard School of Public Health, Boston, USA
N Engl J Med 361:1152-63. 2009..Circulating sex hormone-binding globulin levels are inversely associated with insulin resistance, but whether these levels can predict the risk of developing type 2 diabetes is uncertain...
Common genetic variants of the ion channel transient receptor potential membrane melastatin 6 and 7 (TRPM6 and TRPM7), magnesium intake, and risk of type 2 diabetes in womenYiqing Song
Department of Medicine, Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
BMC Med Genet 10:4. 2009..However, it is unclear whether common genetic variation in TRPM6 and TRPM7 contributes to risk of type 2 diabetes...
Relation of genetic variation in the gene coding for C-reactive protein with its plasma protein concentrations: findings from the Women's Health Initiative Observational CohortCathy C Lee
Department of Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA
Clin Chem 55:351-60. 2009....
Magnesium intake and plasma concentrations of markers of systemic inflammation and endothelial dysfunction in womenYiqing Song
Division of Preventive Medicine and Epidemiology, Harvard School of Public Health, Boston, MA, USA
Am J Clin Nutr 85:1068-74. 2007..Relations between magnesium intake and systemic inflammation and endothelial dysfunction are not well established...
Effects of vitamins C and E and beta-carotene on the risk of type 2 diabetes in women at high risk of cardiovascular disease: a randomized controlled trialYiqing Song
Division of Preventive Medicine and Cardiology Division, Harvard School of Public Health, Boston, MA 02215, USA
Am J Clin Nutr 90:429-37. 2009..Vitamin C, vitamin E, and beta-carotene are major antioxidants and as such may protect against the development of type 2 diabetes via reduction of oxidative stress...
Effect of combined folic acid, vitamin B(6), and vitamin B(12) on colorectal adenomaYiqing Song
Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
J Natl Cancer Inst 104:1562-75. 2012..Folic acid, vitamin B(6), and vitamin B(12) act in concert in the one-carbon metabolism and may protect against colorectal neoplasia. We examined the effect of combined B-vitamin treatment on the occurrence of colorectal adenoma...
Effect of homocysteine-lowering treatment with folic Acid and B vitamins on risk of type 2 diabetes in women: a randomized, controlled trialYiqing Song
Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Diabetes 58:1921-8. 2009..We investigated whether homocysteine-lowering treatment by B vitamin supplementation prevents the risk of type 2 diabetes...
Dietary magnesium intake and risk of incident hypertension among middle-aged and older US women in a 10-year follow-up studyYiqing Song
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Am J Cardiol 98:1616-21. 2006..In conclusion, the results suggest that higher intake of dietary magnesium may have a modest effect on the development of hypertension in women...
Insulin sensitivity and insulin secretion determined by homeostasis model assessment and risk of diabetes in a multiethnic cohort of women: the Women's Health Initiative Observational StudyYiqing Song
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
Diabetes Care 30:1747-52. 2007..However, prospective data regarding its relation to diabetes risk in ethnically diverse populations are limited...
Genetic variants in the UCP2-UCP3 gene cluster and risk of diabetes in the Women's Health Initiative Observational StudyYi Hsiang Hsu
Institute for Aging Research, Hebrew Senior Life and Harvard Medical School, Boston, Massachusetts, USA
Diabetes 57:1101-7. 2008..Genetic variants in the UCP2-UCP3 gene cluster, located on chromosome 11q13, may play a significant role in the development of type 2 diabetes...
Circulating levels of endothelial adhesion molecules and risk of diabetes in an ethnically diverse cohort of womenYiqing Song
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Diabetes 56:1898-904. 2007..S. postmenopausal women, implicating an etiological role of endothelial dysfunction in the pathogenesis of type 2 diabetes...
Dietary calcium, vitamin D, and the prevalence of metabolic syndrome in middle-aged and older U.S. womenSimin Liu
Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215, USA
Diabetes Care 28:2926-32. 2005..To examine whether and to what extent intakes of calcium and vitamin D are related to the metabolic syndrome in middle-aged or older women...
Genome-wide association study identifies nidogen 1 (NID1) as a susceptibility locus to cutaneous nevi and melanoma riskHongmei Nan
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
Hum Mol Genet 20:2673-9. 2011..5 × 10(-6)) and in primary melanoma (P = 4.6 × 10(-4)) compared with the normal skin...
Common genetic variation in calpain-10 gene (CAPN10) and diabetes risk in a multi-ethnic cohort of American postmenopausal womenYiqing Song
Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02215, USA
Hum Mol Genet 16:2960-71. 2007..37 for haplotypes in block 2). In conclusion, we did not observe any significant associations of the common SNPs or haplotypes across the CAPN10 gene with diabetes risk in our large and ethnically diverse cohort of postmenopausal women...
Plasma homocysteine and cysteine and risk of breast cancer in womenJennifer Lin
Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02215, USA
Cancer Res 70:2397-405. 2010..The increased risk of breast cancer associated with high cysteine levels warrants further investigation...
Comparison of usefulness of body mass index versus metabolic risk factors in predicting 10-year risk of cardiovascular events in womenYiqing Song
Department of Medicine, Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 100:1654-8. 2007..In conclusion, MS may largely account for the increased risk of CVD associated with BMI in apparently healthy women...
Asthma, chronic obstructive pulmonary disease, and type 2 diabetes in the Women's Health StudyYiqing Song
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215, USA
Diabetes Res Clin Pract 90:365-71. 2010..Chronic airway inflammation in asthma or chronic obstructive pulmonary disease (COPD) may be involved in the pathogenesis of type 2 diabetes; however, prospective data have been limited...
A prospective study of red meat consumption and type 2 diabetes in middle-aged and elderly women: the women's health studyYiqing Song
Division of Preventive Medicine, Department of Medicine, BrighamWomen's Hospital, Harvard Medical School, 900 Commonwealth Ave. East, Boston, MA 02215, USA
Diabetes Care 27:2108-15. 2004..CONCLUSIONS: Our data indicate that higher consumption of total red meat, especially various processed meats, may increase risk of developing type 2 diabetes in women...
A prospective study of dairy intake and the risk of type 2 diabetes in womenSimin Liu
Division of Preventive Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
Diabetes Care 29:1579-84. 2006..Although studies have indicated that increased dairy intake may reduce risk of overweight and insulin resistance syndrome, data directly relating dairy intake to type 2 diabetes remain sparse...
Vitamin E and risk of type 2 diabetes in the women's health study randomized controlled trialSimin Liu
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Diabetes 55:2856-62. 2006..83-1.04) (P = 0.21) compared with those randomized to placebo. In this large trial with 10-year follow-up, alternate-day doses of 600 IU vitamin E provided no significant benefit for type 2 diabetes in initially healthy women...
Dietary magnesium intake in relation to plasma insulin levels and risk of type 2 diabetes in womenYiqing Song
Division of Preventive Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02215, USA
Diabetes Care 27:59-65. 2004..5 pmol/l among those at the highest quartile (P = 0.03 for trend). CONCLUSIONS: These findings support a protective role of higher intake of magnesium in reducing the risk of developing type 2 diabetes, especially in overweight women...
Dietary intake of whole and refined grain breakfast cereals and weight gain in menLydia A Bazzano
Department of Medicine, Beth Israel Deaconess Hospital, Boston, Massachusetts, USA
Obes Res 13:1952-60. 2005..78 and 0.88; 95% confidence interval, 0.67 to 0.91 and 0.76 to 1.00, respectively). DISCUSSION: BMI and weight gain were inversely associated with intake of breakfast cereals, independently of other risk factors...
Systematic review: Vitamin D and calcium supplementation in prevention of cardiovascular eventsLu Wang
Brigham and Women s Hospital and Harvard School of Public Health, Boston, Massachusetts 02215, USA
Ann Intern Med 152:315-23. 2010..Vitamin D and calcium may affect the cardiovascular system independently and interactively...
A prospective study of the APOA1 XmnI and APOC3 SstI polymorphisms in the APOA1/C3/A4 gene cluster and risk of incident myocardial infarction in menSimin Liu
Department of Medicine, Division of Preventive Medicine, Brigham and Women s Hospital and Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
Atherosclerosis 177:119-26. 2004..However, whether genetic variations in the APOA1/C3/A4 gene cluster are associated with the risk of myocardial infarction (MI) remains uncertain and prospective data are sparse...
A germline variant in the interferon regulatory factor 4 gene as a novel skin cancer risk locusJiali Han
Clinical Research Program, Department of Dermatology, Brigham and Women s Hospital, and Harvard Medical School, Boston, Massachusetts, USA
Cancer Res 71:1533-9. 2011..6 × 10(-3)). Given that the T allele was shown previously to be associated with increased expression of IRF4 locus, further studies are warranted to elucidate the role of the IRF4 gene in human pigmentation and skin cancer development...
Multivitamins, individual vitamin and mineral supplements, and risk of diabetes among older U.S. adultsYiqing Song
Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Diabetes Care 34:108-14. 2011..Understanding the relationship between multivitamin use and diabetes risk is important given the wide use of multivitamin supplements among U.S. adults...
Are variants in the CAPN10 gene related to risk of type 2 diabetes? A quantitative assessment of population and family-based association studiesYiqing Song
Division of Preventive Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02215, USA
Am J Hum Genet 74:208-22. 2004..Our findings also suggest that both large-scale, well-designed association studies and functional studies are warranted to either reliably confirm or conclusively refute the initial hypothesis regarding the role of CAPN10 in T2D risk...
Adverse effects of cyclooxygenase 2 inhibitors on renal and arrhythmia events: meta-analysis of randomized trialsJingjing Zhang
Renal Division, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass, USA
JAMA 296:1619-32. 2006..A COX-2 inhibitor class effect was not evident. Future safety monitoring is warranted and may benefit from an active and continuous cumulative surveillance system...
Sex differences of endogenous sex hormones and risk of type 2 diabetes: a systematic review and meta-analysisEric L Ding
Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass, USA
JAMA 295:1288-99. 2006..High testosterone levels are associated with higher risk of type 2 diabetes in women but with lower risk in men; the inverse association of SHBG with risk was stronger in women than in men...
Is nondiabetic hyperglycemia a risk factor for cardiovascular disease? A meta-analysis of prospective studiesEmily B Levitan
Division of Preventive Medicine, Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02215, USA
Arch Intern Med 164:2147-55. 2004..Although hyperglycemia increases the risk of cardiovascular disease (CVD) in diabetic patients, the risk associated with blood glucose levels in the nondiabetic range remains unsettled...
Meta-analysis: apolipoprotein E genotypes and risk for coronary heart diseaseYiqing Song
Brigham and Women s Hospital, Harvard Medical School, and Harvard School of Public Health, Boston, Massachusetts 02215, USA
Ann Intern Med 141:137-47. 2004..Despite many population studies, however, the impact of apoE polymorphism on risk for CHD remains uncertain...
A prospective study of inflammatory cytokines and diabetes mellitus in a multiethnic cohort of postmenopausal womenSimin Liu
Department of Epidemiology, University of California, Los Angeles, CA 90095 1772, USA
Arch Intern Med 167:1676-85. 2007..However, prospective studies that comprehensively assess their roles in the development of type 2 diabetes are few, especially in minority populations...
Magnesium intake and the metabolic syndrome: epidemiologic evidence to dateKa He
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
J Cardiometab Syndr 1:351-5. 2006..The purpose of this brief review is to summarize the epidemiologic data relating magnesium to the metabolic syndrome and to discuss the potential mechanisms...
Fish consumption and incidence of stroke: a meta-analysis of cohort studiesKa He
Department of Preventive Medicine, The Feinberg School of Medicine, Northwestern University, 680 N Lake Shore Dr, Suite 1102, Chicago, IL 60611, USA
Stroke 35:1538-42. 2004..Results from observational studies on fish consumption and risk of stroke are inconsistent. We quantitatively assessed the relationship between fish intake and incidence of stroke using a meta-analysis of cohort studies...
The tau gene haplotype h1 confers a susceptibility to Parkinson's diseaseJun Zhang
Department of Neurology, The Third Hospital of Beijing University, Beijing, China
Eur Neurol 53:15-21. 2005....
Accuracy of administrative coding for type 2 diabetes in children, adolescents, and young adultsEric L Ding
Diabetes Care 30:e98; author reply e99. 2007
Risks and benefits of omega 3 fats: a few thoughts on systematic reviewKa He
BMJ 332:915; discussion 915-6. 2006
Accumulated evidence on fish consumption and coronary heart disease mortality: a meta-analysis of cohort studiesKa He
Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, 680 North Lake Shore Drive, Suite 1102, Chicago, Ill 60611, USA
Circulation 109:2705-11. 2004..Results from observational studies on fish consumption and coronary heart disease (CHD) mortality are inconsistent...
