Jun S Song

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Monte Carlo calculation of rectal dose when using an intrarectal balloon during prostate radiation therapy
    Jun S Song
    Department of Radiation Oncology, Brigham and Women s Hospital, Boston, MA, USA
    Med Dosim 32:151-6. 2007
  2. pmc Model-based analysis of two-color arrays (MA2C)
    Jun S Song
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA
    Genome Biol 8:R178. 2007
  3. doi request reprint Defining the rectal dose constraint for permanent radioactive seed implantation of the prostate
    Michele Albert
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA
    Urol Oncol 26:147-52. 2008
  4. pmc Identifying positioned nucleosomes with epigenetic marks in human from ChIP-Seq
    Yong Zhang
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, Harvard School of Public Health, 44 Binney St, Boston, MA 02115, USA
    BMC Genomics 9:537. 2008
  5. ncbi request reprint Build-up and surface dose measurements on phantoms using micro-MOSFET in 6 and 10 MV x-ray beams and comparisons with Monte Carlo calculations
    Hong F Xiang
    Department of Radiation Oncology, Dana Farber and Brigham Women s Cancer Center, Harvard Medical School, Boston, Massachusetts 02115, USA
    Med Phys 34:1266-73. 2007
  6. pmc Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF
    Rizwan Haq
    Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Cancer Cell 23:302-15. 2013
  7. pmc Chromatin structure analyses identify miRNA promoters
    Fatih Ozsolak
    Department of Dermatology and Cutaneous Biology Research Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Genes Dev 22:3172-83. 2008
  8. pmc BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition
    Rizwan Haq
    Division of Medical Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 110:4321-6. 2013
  9. pmc YY1 regulates melanocyte development and function by cooperating with MITF
    Juying Li
    Department of Dermatology, Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    PLoS Genet 8:e1002688. 2012
  10. ncbi request reprint Microarray blob-defect removal improves array analysis
    Jun S Song
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, Harvard School of Public Health, Boston, MA, USA
    Bioinformatics 23:966-71. 2007

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Monte Carlo calculation of rectal dose when using an intrarectal balloon during prostate radiation therapy
    Jun S Song
    Department of Radiation Oncology, Brigham and Women s Hospital, Boston, MA, USA
    Med Dosim 32:151-6. 2007
    ..Differential dose volume histograms are also computed and compared for individual fields in the anterior expansion of the rectum, and the TPS is again shown to predict higher mean dose in the region by 0.3 approximately 1.0 Gy...
  2. pmc Model-based analysis of two-color arrays (MA2C)
    Jun S Song
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA
    Genome Biol 8:R178. 2007
    ..The tools have been implemented as a stand-alone Java program called MA2C, which can display various plots of statistical analysis for quality control...
  3. doi request reprint Defining the rectal dose constraint for permanent radioactive seed implantation of the prostate
    Michele Albert
    Department of Radiation Oncology, Brigham and Women s Hospital and Dana Farber Cancer Institute, Boston, MA 02115, USA
    Urol Oncol 26:147-52. 2008
    ..This study was performed to define the rectal dose constraint that would predict late rectal bleeding requiring argon plasma coagulation (APC) following prostate brachy mono-therapy...
  4. pmc Identifying positioned nucleosomes with epigenetic marks in human from ChIP-Seq
    Yong Zhang
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, Harvard School of Public Health, 44 Binney St, Boston, MA 02115, USA
    BMC Genomics 9:537. 2008
    ..In vivo positioning and covalent modifications of nucleosomes play an important role in epigenetic regulation, but genome-wide studies of positioned nucleosomes and their modifications in human still remain limited...
  5. ncbi request reprint Build-up and surface dose measurements on phantoms using micro-MOSFET in 6 and 10 MV x-ray beams and comparisons with Monte Carlo calculations
    Hong F Xiang
    Department of Radiation Oncology, Dana Farber and Brigham Women s Cancer Center, Harvard Medical School, Boston, Massachusetts 02115, USA
    Med Phys 34:1266-73. 2007
    ..0%-3.5%, and 1%-2% systematical error due to phantom setup geometry asymmetry. Micro-MOSFET can be used for skin dose measurements in 6 and 10 MV beams with an estimated accuracy of +/- 6%...
  6. pmc Oncogenic BRAF regulates oxidative metabolism via PGC1α and MITF
    Rizwan Haq
    Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
    Cancer Cell 23:302-15. 2013
    ..Conversely, treatment of BRAF-mutated melanomas with BRAF inhibitors renders them addicted to oxidative phosphorylation. Our data thus identify an adaptive metabolic program that limits the efficacy of BRAF inhibitors...
  7. pmc Chromatin structure analyses identify miRNA promoters
    Fatih Ozsolak
    Department of Dermatology and Cutaneous Biology Research Center, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Genes Dev 22:3172-83. 2008
    ..The high-throughput identification of miRNA promoter and enhancer regulatory elements sheds light on evolution of miRNA transcription and permits rapid identification of transcriptional networks of miRNAs...
  8. pmc BCL2A1 is a lineage-specific antiapoptotic melanoma oncogene that confers resistance to BRAF inhibition
    Rizwan Haq
    Division of Medical Oncology, Department of Medicine, Massachusetts General Hospital, Boston, MA 02115, USA
    Proc Natl Acad Sci U S A 110:4321-6. 2013
    ..These studies identify MITF-BCL2A1 as a lineage-specific oncogenic pathway in melanoma and underscore its role for improved response to BRAF-directed therapy...
  9. pmc YY1 regulates melanocyte development and function by cooperating with MITF
    Juying Li
    Department of Dermatology, Cutaneous Biology Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
    PLoS Genet 8:e1002688. 2012
    ....
  10. ncbi request reprint Microarray blob-defect removal improves array analysis
    Jun S Song
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, Harvard School of Public Health, Boston, MA, USA
    Bioinformatics 23:966-71. 2007
    ....
  11. pmc A high-resolution map of nucleosome positioning on a fission yeast centromere
    Jun S Song
    Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Genome Res 18:1064-72. 2008
    ..In addition, sequence analysis of nucleosome-free regions identifies novel binding sites of Ams2p. We conclude that centromeric nucleosome positions are stable and may be derived from the underlying DNA sequence...
  12. ncbi request reprint High-throughput mapping of the chromatin structure of human promoters
    Fatih Ozsolak
    Melanoma Program in Medical Oncology, and Department of Pediatric Oncology, Dana Farber Cancer Institute, Children s Hospital Boston, Harvard Medical School, 44 Binney Street, Boston, Massachusetts 02115, USA
    Nat Biotechnol 25:244-8. 2007
    ..This study presents a global view of human nucleosome positioning and provides a high-throughput tool for analyzing chromatin structure in development and disease...
  13. ncbi request reprint A comparative study of rectal dose histograms in prostate brachytherapy: some analytic and numerical results
    Jun S Song
    Department of Radiation Oncology, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Med Phys 32:437-47. 2005
    ..The digitized computation agrees quite well with the pre-digitization numerical integration, within 1% or 0.2 cm3, because of the low dose-gradient effect near the rectum in prostate brachytherapy...
  14. pmc Lineage-specific transcriptional regulation of DICER by MITF in melanocytes
    Carmit Levy
    Department of Dermatology, Cutaneous Biology Research Center, Mass General Hospital, Harvard Medical School, MA 02115, USA
    Cell 141:994-1005. 2010
    ..These observations highlight a central mechanism underlying lineage-specific miRNA regulation which could exist for other cell types during development...
  15. pmc Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets
    David S Johnson
    Department of Genetics, Stanford University Medical Center, Stanford, California 94305, USA
    Genome Res 18:393-403. 2008
    ..The spike-in DNA samples and the data presented here provide a stable benchmark against which future ChIP platforms, protocol improvements, and analysis methods can be evaluated...