M P Soares

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Differential inhibition of B-cell development and xenoreactive natural antibody production by administration of anti-mu or anti-delta monoclonal antibodies in adult rats
    M Soares
    Experimental Immunology Unit, Faculty of Medicine, University of Louvain, Brussels, Belgium
    Transplantation 66:357-64. 1998
  2. ncbi request reprint Expression of heme oxygenase-1 can determine cardiac xenograft survival
    M P Soares
    Immunobiology Research Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Nat Med 4:1073-7. 1998
  3. ncbi request reprint Long-term survival of hamster hearts in presensitized rats
    Y Lin
    Immunobiology Research Center, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    J Immunol 164:4883-92. 2000
  4. ncbi request reprint Accommodated xenografts survive in the presence of anti-donor antibodies and complement that precipitate rejection of naive xenografts
    Y Lin
    Immunobiology Research Center, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Immunol 163:2850-7. 1999
  5. ncbi request reprint Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants
    K Sato
    Immunobiology Research Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    J Immunol 166:4185-94. 2001
  6. pmc Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis
    S Brouard
    Immunobiology Research Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Exp Med 192:1015-26. 2000
  7. ncbi request reprint Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cells
    J Anrather
    Immunobiology Research Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biol Chem 274:13594-603. 1999
  8. ncbi request reprint Heavy chain ferritin acts as an antiapoptotic gene that protects livers from ischemia reperfusion injury
    P O Berberat
    Immunobiology Research Center, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    FASEB J 17:1724-6. 2003
  9. ncbi request reprint Heme oxygenase-1, a protective gene that prevents the rejection of transplanted organs
    M P Soares
    Beth Israel Deaconess Medical Center, Department of Surgery, Harvard Medical School, Boston, MA 02215, USA
    Immunol Rev 184:275-85. 2001
  10. ncbi request reprint Statin-mediated cytoprotection of human vascular endothelial cells: a role for Kruppel-like factor 2-dependent induction of heme oxygenase-1
    F Ali
    Bywaters Centre for Vascular Inflammation, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK
    J Thromb Haemost 5:2537-46. 2007

Collaborators

Detail Information

Publications10

  1. ncbi request reprint Differential inhibition of B-cell development and xenoreactive natural antibody production by administration of anti-mu or anti-delta monoclonal antibodies in adult rats
    M Soares
    Experimental Immunology Unit, Faculty of Medicine, University of Louvain, Brussels, Belgium
    Transplantation 66:357-64. 1998
    ....
  2. ncbi request reprint Expression of heme oxygenase-1 can determine cardiac xenograft survival
    M P Soares
    Immunobiology Research Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Nat Med 4:1073-7. 1998
    ..We show here that the expression of the HO-1 gene is functionally associated with xenograft survival, and that rapid expression of HO-1 in cardiac xenografts can be essential to ensure long-term xenograft survival...
  3. ncbi request reprint Long-term survival of hamster hearts in presensitized rats
    Y Lin
    Immunobiology Research Center, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    J Immunol 164:4883-92. 2000
    ..Th2 responses and protective genes are associated with resistance to IgM- and IgG-mediated, complement-dependent and -independent forms of rejection...
  4. ncbi request reprint Accommodated xenografts survive in the presence of anti-donor antibodies and complement that precipitate rejection of naive xenografts
    Y Lin
    Immunobiology Research Center, Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    J Immunol 163:2850-7. 1999
    ..We hypothesize that this resistance involves expression by accommodated xenografts of protective genes...
  5. ncbi request reprint Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants
    K Sato
    Immunobiology Research Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    J Immunol 166:4185-94. 2001
    ..Additional mechanisms by which CO overcomes graft rejection may involve its ability to suppress endothelial cell apoptosis...
  6. pmc Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis
    S Brouard
    Immunobiology Research Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Exp Med 192:1015-26. 2000
    ..Taken together, these data demonstrate that the antiapoptotic effect of HO-1 in ECs is mediated by CO and more specifically via the activation of p38 MAPK by CO...
  7. ncbi request reprint Regulation of NF-kappaB RelA phosphorylation and transcriptional activity by p21(ras) and protein kinase Czeta in primary endothelial cells
    J Anrather
    Immunobiology Research Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Biol Chem 274:13594-603. 1999
    ..Raf/MEK, small GTPases, phosphatidylinositol 3-kinase, and stress-activated protein kinase pathways are not involved in this mechanism of regulation...
  8. ncbi request reprint Heavy chain ferritin acts as an antiapoptotic gene that protects livers from ischemia reperfusion injury
    P O Berberat
    Immunobiology Research Center, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    FASEB J 17:1724-6. 2003
    ..These findings unveil the anti-apoptotic function of H-ferritin and suggest that H-ferritin can be used in a therapeutic manner to prevent liver IRI and thus maximize the organ donor pool used for transplantation...
  9. ncbi request reprint Heme oxygenase-1, a protective gene that prevents the rejection of transplanted organs
    M P Soares
    Beth Israel Deaconess Medical Center, Department of Surgery, Harvard Medical School, Boston, MA 02215, USA
    Immunol Rev 184:275-85. 2001
    ..The data reviewed focus on the role of one of such genes, the stress responsive gene heme oxygenase-1, and of its byproduct carbon monoxide, which can suppress graft rejection and lead to long-term graft survival...
  10. ncbi request reprint Statin-mediated cytoprotection of human vascular endothelial cells: a role for Kruppel-like factor 2-dependent induction of heme oxygenase-1
    F Ali
    Bywaters Centre for Vascular Inflammation, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK
    J Thromb Haemost 5:2537-46. 2007
    ..This led to an investigation of the role of HO-1 in statin-mediated cytoprotection in primary human endothelial cells (ECs), and the ability of Kruppel-like factor 2 (KLF2) to regulate HO-1 function...