Affiliation: Harvard University
- Effects of central nervous system antiretroviral penetration on cognitive functioning in the ALLRT cohortMarlene Smurzynski
Harvard School of Public Health, Department of Biostatistics, Boston, Massachusetts 02115, USA
AIDS 25:357-65. 2011..We assessed the relationship between estimates of antiretroviral therapy penetration into the CNS, using a published ranking system, and neurocognitive status in HIV-positive participants with plasma HIV-1 RNA (vRNA) suppression...
- AIDS clinical trials group longitudinal linked randomized trials (ALLRT): rationale, design, and baseline characteristicsMarlene Smurzynski
Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, Massachusetts 02115, USA
HIV Clin Trials 9:269-82. 2008..We describe the rationale, design, and baseline characteristics of the ALLRT cohort and its potential to address important research questions related to ARV therapy...
- Relationship between CD4+ T-cell counts/HIV-1 RNA plasma viral load and AIDS-defining events among persons followed in the ACTG longitudinal linked randomized trials studyMarlene Smurzynski
Department of Biostatistics, Harvard School of Public Health, Boston, MA, USA
J Acquir Immune Defic Syndr 55:117-27. 2010..AIDS-defining events (ADEs) decreased in the era of highly active antiretroviral therapy but still lead to hospitalizations and deaths. Understanding factors related to ADEs is important to mitigate events...
- Factors associated with remaining on initial randomized efavirenz-containing regimensMarlene Smurzynski
aCenter for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, Massachusetts bFred Hutchinson Cancer Research Center, Seattle, Washington cUniversity of Washington, Seattle, Washington dNorthwestern University Feinberg School of Medicine, Division of Infectious Diseases, Chicago, Illinois eBirmingham Veterans Affairs Medical Center and University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA
AIDS 27:1887-97. 2013..Efavirenz (EFV) along with two nucleoside reverse transcriptase inhibitors (NRTIs) is a recommended initial antiretroviral regimen. Understanding characteristics related to EFV success is clinically useful...
- No risk of myocardial infarction associated with initial antiretroviral treatment containing abacavir: short and long-term results from ACTG A5001/ALLRTHeather J Ribaudo
Center for Biostatistics in AIDS Research, Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Clin Infect Dis 52:929-40. 2011....
- Virologic and serologic outcomes of mono versus dual HBV therapy and characterization of HIV/HBV coinfection in a US cohortMinhee Kang
Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, MA Department of Medicine, Division of Infectious Diseases, New York University, New York, NY Division of Infectious Diseases, Ohio State University, Columbus, OH and Department of Epidemiology and Biostatistics, George Washington University Milken Institute, School of Public Health, Washington, DC
J Acquir Immune Defic Syndr 66:172-80. 2014..To characterize HIV/hepatitis B virus (HBV) coinfection in the AIDS Clinical Trials Group Longitudinal Linked Randomized Trials cohort and compare long-term HBV outcomes between regimens with 1 (MONO) or 2 (DUAL) anti-HBV agents...
- Suppression of HIV-1 replication by antiretroviral therapy improves renal function in persons with low CD4 cell counts and chronic kidney diseaseRobert C Kalayjian
Department of Medicine, MetroHealth Medical Center, Cleveland, Ohio, USA
AIDS 22:481-7. 2008..To examine the association between changes in glomerular filtration rates (GFR) and antiretroviral therapy (ART)-mediated suppression of plasma HIV-1 viremia...
- The prevalence and incidence of neurocognitive impairment in the HAART eraKevin R Robertson
Department of Neurology, UNC, Chapel Hill, North Carolina 27599, USA
AIDS 21:1915-21. 2007..The effects of HAART on neurological disease are less well understood. The aim of this study was to assess the prevalence and incidence of neurocognitive impairment in individuals who initiated HAART as part of an AIDS clinical trial...
- Key components of a theory-guided HIV prevention outreach model: pre-outreach preparation, community assessment, and a network of key informantsChandra L Ford
Department of Social Medicine, School of Medicine, University of North Carolina at Chapel Hill, USA
AIDS Educ Prev 19:173-86. 2007..This model enabled a systematic approach to reaching community members and documenting the steps taken to do so...
- Predictors of repeat testing and HIV seroconversion in a sexually transmitted disease clinic populationLisa B Hightow
Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Sex Transm Dis 31:455-9. 2004..This study assessed the extent of and characteristics associated with repeat HIV testing in persons presenting to a sexually transmitted disease (STD) clinic...
- Failure to return for HIV posttest counseling in an STD clinic populationLisa B Hightow
Department of Medicine, University of North Carolina at Chapel Hill, USA
AIDS Educ Prev 15:282-90. 2003..To maximize the potential benefit of counseling and testing, interventions need to be designed to target those at highest risk of not returning...
- Real-time, universal screening for acute HIV infection in a routine HIV counseling and testing populationChristopher D Pilcher
Department of Medicien, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7030, USA
JAMA 288:216-21. 2002..However, HIV nucleic acid-based testing is widely used to screen for antibody-negative acute infection among low-risk blood donors...