Kiersten S Smith

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Behavioral responses during the initial exposures to a low dose of cocaine in late preweanling and adult rats
    Kiersten S Smith
    Center for Molecular and Behavioral Neuroscience, Rutgers University, USA
    Neurotoxicol Teratol 30:202-12. 2008
  2. pmc Reduction of fear-potentiated startle by benzodiazepines in C57BL/6J mice
    Kiersten S Smith
    Department of Psychiatry, McLean Hospital and Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA
    Psychopharmacology (Berl) 213:697-706. 2011
  3. pmc Behavioral differences between late preweanling and adult female Sprague-Dawley rat exploration of animate and inanimate stimuli and food
    Kiersten S Smith
    Department of Psychiatry, Harvard Medical School, Belmont, MA 02478, USA
    Behav Brain Res 217:326-36. 2011
  4. pmc Benzodiazepine-induced anxiolysis and reduction of conditioned fear are mediated by distinct GABAA receptor subtypes in mice
    Kiersten S Smith
    Laboratory of Genetic Neuropharmacology, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Neuropharmacology 63:250-8. 2012
  5. pmc Comparison of infant and adult rats in exploratory activity, diurnal patterns, and responses to novel and anxiety-provoking environments
    Kiersten S Smith
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, US
    Behav Neurosci 121:449-61. 2007
  6. pmc Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels
    Antonio Riccio
    Howard Hughes Medical Institute, Department of Cardiology, Boston Children s Hospital, Boston, Massachusetts 02115, Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Massachusetts 02478, and Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St Petersburg 194223, Russia
    J Neurosci 34:3653-67. 2014
  7. pmc Anxiety and depression: mouse genetics and pharmacological approaches to the role of GABA(A) receptor subtypes
    Kiersten S Smith
    Laboratory of Genetic Neuropharmacology, McLean Hospital, Belmont, MA, USA
    Neuropharmacology 62:54-62. 2012
  8. pmc Neural Basis of Benzodiazepine Reward: Requirement for α2 Containing GABAA Receptors in the Nucleus Accumbens
    Elif Engin
    1 Laboratory of Genetic Neuropharmacology, McLean Hospital, Belmont, MA, USA 2 Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Neuropsychopharmacology 39:1805-15. 2014
  9. pmc Antidepressant-like properties of α2-containing GABA(A) receptors
    Isabel Vollenweider
    Laboratory of Genetic Neuropharmacology, McLean Hospital, and Department of Psychiatry, Harvard Medical School, Belmont, MA 02478, USA
    Behav Brain Res 217:77-80. 2011

Collaborators

Detail Information

Publications9

  1. pmc Behavioral responses during the initial exposures to a low dose of cocaine in late preweanling and adult rats
    Kiersten S Smith
    Center for Molecular and Behavioral Neuroscience, Rutgers University, USA
    Neurotoxicol Teratol 30:202-12. 2008
    ..The behavioral patterns of this age group offer a preclinical model of the early effects of drugs of abuse...
  2. pmc Reduction of fear-potentiated startle by benzodiazepines in C57BL/6J mice
    Kiersten S Smith
    Department of Psychiatry, McLean Hospital and Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA
    Psychopharmacology (Berl) 213:697-706. 2011
    ..Recent surges in the diagnosis of posttraumatic stress disorder (PTSD) from combat-exposed veterans have prompted an urgent need to understand the pathophysiology underlying this debilitating condition...
  3. pmc Behavioral differences between late preweanling and adult female Sprague-Dawley rat exploration of animate and inanimate stimuli and food
    Kiersten S Smith
    Department of Psychiatry, Harvard Medical School, Belmont, MA 02478, USA
    Behav Brain Res 217:326-36. 2011
    ..These data provide a basis for the use of the preweanling as a preclinical model for understanding and medicating human disorders during development that are characterized by dysfunctional interactions with specific stimuli...
  4. pmc Benzodiazepine-induced anxiolysis and reduction of conditioned fear are mediated by distinct GABAA receptor subtypes in mice
    Kiersten S Smith
    Laboratory of Genetic Neuropharmacology, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Neuropharmacology 63:250-8. 2012
    ..This raises the possibility that GABAergic pharmacological interventions for specific anxiety disorders can be differentially tailored...
  5. pmc Comparison of infant and adult rats in exploratory activity, diurnal patterns, and responses to novel and anxiety-provoking environments
    Kiersten S Smith
    Center for Molecular and Behavioral Neuroscience, Rutgers University, Newark, NJ 07102, US
    Behav Neurosci 121:449-61. 2007
    ..Such differences may allow enhanced gathering of environmental information by the infant and are important to consider in the design of experiments using infants...
  6. pmc Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels
    Antonio Riccio
    Howard Hughes Medical Institute, Department of Cardiology, Boston Children s Hospital, Boston, Massachusetts 02115, Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, Massachusetts 02478, and Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St Petersburg 194223, Russia
    J Neurosci 34:3653-67. 2014
    ..Thus, TRPC4 and the structurally and functionally related subunit, TRPC5, may both contribute to the mechanisms underlying regulation of innate fear responses. ..
  7. pmc Anxiety and depression: mouse genetics and pharmacological approaches to the role of GABA(A) receptor subtypes
    Kiersten S Smith
    Laboratory of Genetic Neuropharmacology, McLean Hospital, Belmont, MA, USA
    Neuropharmacology 62:54-62. 2012
    ..This article is part of a Special Issue entitled 'Anxiety and Depression'...
  8. pmc Neural Basis of Benzodiazepine Reward: Requirement for α2 Containing GABAA Receptors in the Nucleus Accumbens
    Elif Engin
    1 Laboratory of Genetic Neuropharmacology, McLean Hospital, Belmont, MA, USA 2 Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Neuropsychopharmacology 39:1805-15. 2014
    ..Findings imply that α2GABAARs in the NAc are involved in at least some reward-related properties of benzodiazepines, which might partially underlie repeated drug-taking behavior. ..
  9. pmc Antidepressant-like properties of α2-containing GABA(A) receptors
    Isabel Vollenweider
    Laboratory of Genetic Neuropharmacology, McLean Hospital, and Department of Psychiatry, Harvard Medical School, Belmont, MA 02478, USA
    Behav Brain Res 217:77-80. 2011
    ..2-containing GABA(A) receptors may therefore represent a novel target for the development of more effective antidepressants...