Jennifer A Sinnott

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Artifact due to differential error when cases and controls are imputed from different platforms
    Jennifer A Sinnott
    Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA
    Hum Genet 131:111-9. 2012
  2. pmc Molecular differences in transition zone and peripheral zone prostate tumors
    Jennifer A Sinnott
    Department of Epidemiology and Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA, Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Carcinogenesis 36:632-8. 2015
  3. pmc Tumor expression of adiponectin receptor 2 and lethal prostate cancer
    Jennifer R Rider
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Carcinogenesis 36:639-47. 2015
  4. pmc Association of prostate cancer risk variants with gene expression in normal and tumor tissue
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts
    Cancer Epidemiol Biomarkers Prev 24:255-60. 2015
  5. pmc Gleason grade progression is uncommon
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Res 73:5163-8. 2013
  6. pmc mRNA expression signature of Gleason grade predicts lethal prostate cancer
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    J Clin Oncol 29:2391-6. 2011
  7. pmc Omnibus risk assessment via accelerated failure time kernel machine modeling
    Jennifer A Sinnott
    Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Boston, Massachusetts 02115, U S A
    Biometrics 69:861-73. 2013
  8. pmc Genome-wide association study of prostate cancer mortality
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Cancer Epidemiol Biomarkers Prev 19:2869-76. 2010

Detail Information

Publications8

  1. pmc Artifact due to differential error when cases and controls are imputed from different platforms
    Jennifer A Sinnott
    Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA
    Hum Genet 131:111-9. 2012
    ..Every SNP found with genome-wide significance should be validated on another platform to verify that its significance is not an artifact of study design...
  2. pmc Molecular differences in transition zone and peripheral zone prostate tumors
    Jennifer A Sinnott
    Department of Epidemiology and Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA, Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Carcinogenesis 36:632-8. 2015
    ..Zone of origin may be important to consider in prostate tumor biomarker research. ..
  3. pmc Tumor expression of adiponectin receptor 2 and lethal prostate cancer
    Jennifer R Rider
    Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Carcinogenesis 36:639-47. 2015
    ..2-3.0). Results were similar when additionally controlling for categories of PSA at diagnosis and Ki-67 expression quartiles. These results strengthen the evidence for the role of AdipoR2 in prostate cancer progression. ..
  4. pmc Association of prostate cancer risk variants with gene expression in normal and tumor tissue
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts Channing Division of Network Medicine, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts
    Cancer Epidemiol Biomarkers Prev 24:255-60. 2015
    ..One possibility is that these variants influence gene expression in prostate tissue. We therefore examined the association of prostate cancer risk variants with the expression of genes nearby and genome-wide...
  5. pmc Gleason grade progression is uncommon
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Cancer Res 73:5163-8. 2013
    ..This has implications for the understanding of tumor progression and prognosis, and may help patients diagnosed with lower grade disease feel more comfortable choosing active surveillance...
  6. pmc mRNA expression signature of Gleason grade predicts lethal prostate cancer
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    J Clin Oncol 29:2391-6. 2011
    ....
  7. pmc Omnibus risk assessment via accelerated failure time kernel machine modeling
    Jennifer A Sinnott
    Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Boston, Massachusetts 02115, U S A
    Biometrics 69:861-73. 2013
    ..We propose a robust Omnibus Test that combines information across kernels, and an approach for selecting the best kernel for estimation. The methods are illustrated with an application in breast cancer. ..
  8. pmc Genome-wide association study of prostate cancer mortality
    Kathryn L Penney
    Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Cancer Epidemiol Biomarkers Prev 19:2869-76. 2010
    ..Identifying genetic variants associated with lethal prostate cancer could inform clinical decision making...