Research Topics
| M M SilveriSummaryAffiliation: Harvard University Country: USA Publications
Research Grants
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Detail Information
Publications
Adolescent brain development and underage drinking in the United States: identifying risks of alcohol use in college populationsMarisa M Silveri
Harvard Medical School, Belmont, MA 02478, USA
Harv Rev Psychiatry 20:189-200. 2012....
Preliminary evidence for white matter metabolite differences in marijuana-dependent young men using 2D J-resolved magnetic resonance spectroscopic imaging at 4 TeslaMarisa M Silveri
Brain Imaging Center, McLean Hospital, Belmont, MA, USA Department of Psychiatry, Harvard Medical School, Boston, MA 02478, USA
Psychiatry Res 191:201-11. 2011..These preliminary findings suggest that mI, and distribution of this glial metabolite in WM, is altered by MRJ use and is associated with behavioral and affective features reported by young MRJ-dependent men...
Adolescents at risk for alcohol abuse demonstrate altered frontal lobe activation during Stroop performanceMarisa M Silveri
Brain Imaging Center, McLean Hospital, Belmont, Massachusetts 02478, USA
Alcohol Clin Exp Res 35:218-28. 2011....
Citicoline enhances frontal lobe bioenergetics as measured by phosphorus magnetic resonance spectroscopyM M Silveri
Cognitive Neuroimaging Laboratory, McLean Hospital and Harvard Medical School, 115 Mill Street, Belmont, MA 02478 9106, USA
NMR Biomed 21:1066-75. 2008....
Relationship between white matter volume and cognitive performance during adolescence: effects of age, sex and risk for drug useMarisa M Silveri
Cognitive Neuroimaging Laboratory, Brain Imaging Center, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
Addiction 103:1509-20. 2008..The present study examined the relationship between white matter volume and cognitive processing speed in adolescents with and without a familial substance abuse history...
Sex differences in the relationship between white matter microstructure and impulsivity in adolescentsMarisa M Silveri
Cognitive Neuroimaging and Neuropsychology Laboratory, McLean Hospital, Belmont, MA 02478, USA
Magn Reson Imaging 24:833-41. 2006..These data further suggest a neurobiological mechanism underlying some of the emotional and cognitive changes commonly observed in males versus females during the adolescent period...
Characterizing the ontogeny of ethanol-associated increases in corticosteroneMarisa M Silveri
Department of Psychiatry, Harvard Medical School, and Cognitive Neuroimaging Laboratory, McLean Hospital, Belmont, MA 02478, USA
Alcohol 32:145-55. 2004....
White matter abnormalities observed in bipolar disorder: a diffusion tensor imaging studyDeborah A Yurgelun-Todd
Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Bipolar Disord 9:504-12. 2007..The objective of the present study was to examine white matter tract integrity, using diffusion tensor imaging (DTI), in bipolar patients and healthy comparison subjects...
Differences in regional blood volume during a 28-day period of abstinence in chronic cannabis smokersJennifer T Sneider
Cognitive Neuroimaging Laboratory, Brain Imaging Center, McLean Hospital, Belmont, MA 02478, United States
Eur Neuropsychopharmacol 18:612-9. 2008..These findings suggest that while CBV levels begin to normalize with continued abstinence from cannabis, specifically in frontal areas, other temporal and cerebellar brain regions show slower CBV decreases...
Trajectories of adolescent emotional and cognitive development: effects of sex and risk for drug useMarisa M Silveri
Cognitive Neuroimaging Laboratory, Brain Imaging Center, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
Ann N Y Acad Sci 1021:363-70. 2004..Furthermore, these data also suggest that history of familial drug abuse may have a more pronounced impact on emotional and cognitive development in adolescent girls than boys...
Altered regional blood volume in chronic cannabis smokersJennifer T Sneider
Cognitive Neuroimaging Laboratory, Brain Imaging Center, McLean Hospital, Belmont, MA 02478, USA
Exp Clin Psychopharmacol 14:422-8. 2006..It would be of interest to extend the investigation beyond 6-36 hr of abstinence from cannabis to determine whether increased CBV values persist for several weeks or eventually normalize...
Cerebral phosphorus metabolite and transverse relaxation time abnormalities in heroin-dependent subjects at onset of methadone maintenance treatmentMarisa M Silveri
Brain Imaging Center, McLean Hospital, Department of Psychiatry, Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA
Psychiatry Res 131:217-26. 2004..Taken together, these cross-sectional data suggest that the first month of MM treatment may be associated with altered cerebral bioenergetics and phospholipid metabolite levels...
Methadone maintenance improves cognitive performance after two months of treatmentStaci A Gruber
Cognitive Neuroimaging Laboratory, McLean Hospital, Belmont, MA 02478, USA
Exp Clin Psychopharmacol 14:157-64. 2006..Results suggest that opiate-dependent subjects exhibit significant improvement in cognitive function after MM treatment. Future investigations are needed to confirm these findings...
Functional magnetic resonance imaging studies of schizophrenic patients during word production: effects of D-cycloserineDeborah A Yurgelun-Todd
Cognitive Neuroimaging Laboratory, Brain Imaging Center, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
Psychiatry Res 138:23-31. 2005..These results suggest that the addition of D-cycloserine to conventional neuroleptics may improve negative symptoms through enhanced temporal lobe function...
White matter hyperintensities in subjects with cocaine and opiate dependence and healthy comparison subjectsIn Kyoon Lyoo
McLean Hospital Brain Imaging Center and Department of Psychiatry, Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA
Psychiatry Res 131:135-45. 2004..Also, there was a trend for lower WMH severity in substance-dependent women relative to the healthy comparison group, possibly due to estrogen's protective effect against cerebrovascular accidents...
Neuropsychological consequences of opiate useStaci A Gruber
Cognitive Neuroimaging Laboratory, McLean Hospital Harvard Medical School, 115 Mill Street, Belmont, MA 02478, USA
Neuropsychol Rev 17:299-315. 2007..Factors that contribute to addiction and recovery are also discussed, as it is difficult to disentangle the effects of opiate use on cognitive performance from other factors that may affect neurobehavioral measures...
The effects of NMDA and GABAA pharmacological manipulations on acute and rapid tolerance to ethanol during ontogenyM M Silveri
Department of Psychiatry, Harvard Medical School and Cognitive Neuroimaging and Neuropsychology Laboratory, Brain Imaging Center, McLean Hospital, Belmont, Massachusetts 02478, USA
Alcohol Clin Exp Res 28:884-94. 2004..In contrast, rapid tolerance to ethanol-induced sedation emerges slowly during ontogeny. This study tested the hypothesis that ontogenetic differences in glutamate and/or gamma-aminobutyric acid systems influence tolerance expression...
Oral methylphenidate challenge selectively decreases putaminal T2 in healthy subjectsMarisa M Silveri
Brain Imaging Center, McLean Hospital and Department of Psychiatry, Harvard Medical School, Belmont, MA 02478, USA
Drug Alcohol Depend 76:173-80. 2004..These data suggest that T2 relaxometry can be used to study the time course of regional cerebral blood volume responses to MPH and perhaps to other stimulant drugs...
Prefrontal and temporal gray matter density decreases in opiate dependenceIn Kyoon Lyoo
McLean Hospital Brain Imaging Center and Department of Psychiatry, Harvard Medical School, Belmont, MA, USA
Psychopharmacology (Berl) 184:139-44. 2006..There have been only a few structural brain-imaging studies, with varied findings, of opiate-dependent subjects. Voxel-based morphometry (VBM) is suitable for studying whole brain-wise structural brain changes in opiate-dependent subjects...
Performance on the Stroop predicts treatment compliance in cocaine-dependent individualsChris C Streeter
Division of Psychiatry, Boston University School of Medicine, Boston, MA 02118, USA
Neuropsychopharmacology 33:827-36. 2008..The Stroop task is a widely available, reliable, and valid instrument that can be easily employed to identify and tailor interventions of at risk individuals in the hope of improving treatment compliance...
S-adenosyl-L-methionine: effects on brain bioenergetic status and transverse relaxation time in healthy subjectsMarisa M Silveri
Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Biol Psychiatry 54:833-9. 2003..These findings suggest that S-adenosyl-L-methionine alters parameters associated with cerebral bioenergetic status and that some effects of S-adenosyl-L-methionine (T2RT) occur in a gender-specific manner...
Research Grants
- Neurobiological consequences of binge alcohol consumption in young adultsMarisa M Silveri; Fiscal Year: 2010....
- Neurocognition, Brain GABA & Adolescent Alcohol UseMARISA SILVERI; Fiscal Year: 2007..Findings from the proposed study will document the impact of alcohol use on the central nervous system during development, which has implications for both identification and treatment of alcohol-related disorders. ..
