Peter J Siekmeier

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Development of antipsychotic medications with novel mechanisms of action based on computational modeling of hippocampal neuropathology
    Peter J Siekmeier
    Laboratory for Computational Neuroscience, McLean Hospital, Belmont, Massachusetts, United States of America
    PLoS ONE 8:e58607. 2013
  2. ncbi Modeling of context-dependent retrieval in hippocampal region CA1: implications for cognitive function in schizophrenia
    Peter J Siekmeier
    Department of Psychiatry, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Schizophr Res 89:177-90. 2007
  3. ncbi Evidence of multistability in a realistic computer simulation of hippocampus subfield CA1
    Peter J Siekmeier
    Harvard Medical School and McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Behav Brain Res 200:220-31. 2009
  4. ncbi Patterns of spontaneous magnetoencephalographic activity in patients with schizophrenia
    Peter J Siekmeier
    Harvard Medical School and McLean Hospital, Belmont, Massachusetts 02478, USA
    J Clin Neurophysiol 27:179-90. 2010
  5. ncbi Enhanced semantic priming in schizophrenia: a computer model based on excessive pruning of local connections in association cortex
    Peter J Siekmeier
    Department of Psychiatry, McLean Hospital, Belmont, Massachusetts, USA
    Br J Psychiatry 180:345-50. 2002

Research Grants

  1. Computational Modeling of Hippocampus in Schizophrenia
    Peter Siekmeier; Fiscal Year: 2007

Detail Information

Publications5

  1. ncbi Development of antipsychotic medications with novel mechanisms of action based on computational modeling of hippocampal neuropathology
    Peter J Siekmeier
    Laboratory for Computational Neuroscience, McLean Hospital, Belmont, Massachusetts, United States of America
    PLoS ONE 8:e58607. 2013
    ..As such, they generate specific falsifiable hypotheses, which can guide postmortem and other laboratory research. Significantly, this work also suggests specific non-obvious targets for potential pharmacologic agents...
  2. ncbi Modeling of context-dependent retrieval in hippocampal region CA1: implications for cognitive function in schizophrenia
    Peter J Siekmeier
    Department of Psychiatry, McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Schizophr Res 89:177-90. 2007
    ..As such, it can shed light on the etiology of schizophrenia in a fundamental way, and also holds the promise of pointing the way to more effective treatments...
  3. ncbi Evidence of multistability in a realistic computer simulation of hippocampus subfield CA1
    Peter J Siekmeier
    Harvard Medical School and McLean Hospital, 115 Mill Street, Belmont, MA 02478, USA
    Behav Brain Res 200:220-31. 2009
    ..Ways that this methodology could shed light on the etiology of mental illness, such as schizophrenia, are discussed...
  4. ncbi Patterns of spontaneous magnetoencephalographic activity in patients with schizophrenia
    Peter J Siekmeier
    Harvard Medical School and McLean Hospital, Belmont, Massachusetts 02478, USA
    J Clin Neurophysiol 27:179-90. 2010
    ....
  5. ncbi Enhanced semantic priming in schizophrenia: a computer model based on excessive pruning of local connections in association cortex
    Peter J Siekmeier
    Department of Psychiatry, McLean Hospital, Belmont, Massachusetts, USA
    Br J Psychiatry 180:345-50. 2002
    ..Its findings shed light on the mechanisms underlying cognitive priming more generally, and how it might emerge developmentally...

Research Grants2

  1. Computational Modeling of Hippocampus in Schizophrenia
    Peter Siekmeier; Fiscal Year: 2007
    ....