N E Sibinga

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Interferon-gamma-mediated inhibition of cyclin A gene transcription is independent of individual cis-acting elements in the cyclin A promoter
    N E Sibinga
    Cardiovascular Biology Laboratory, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Biol Chem 274:12139-46. 1999
  2. ncbi Embryonic expression suggests an important role for CRP2/SmLIM in the developing cardiovascular system
    M K Jain
    Cardiovascular Biology Laboratory, Harvard School of Public Health, The Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA
    Circ Res 83:980-5. 1998
  3. ncbi Transforming growth factor-beta 1 inhibits cytokine-mediated induction of human metalloelastase in macrophages
    M W Feinberg
    Program of Developmental Cardiovascular Biology, The Department of Medicine, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Biol Chem 275:25766-73. 2000
  4. ncbi Characterization of the mUBC9-binding sites required for E2A protein degradation
    G S Huggins
    Cardiovascular Biology Laboratory, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Biol Chem 274:28690-6. 1999
  5. ncbi Molecular cloning and characterization of SmLIM, a developmentally regulated LIM protein preferentially expressed in aortic smooth muscle cells
    M K Jain
    Cardiovascular Biology Laboratory, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Biol Chem 271:10194-9. 1996

Collaborators

Detail Information

Publications5

  1. ncbi Interferon-gamma-mediated inhibition of cyclin A gene transcription is independent of individual cis-acting elements in the cyclin A promoter
    N E Sibinga
    Cardiovascular Biology Laboratory, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Biol Chem 274:12139-46. 1999
    ..We hypothesize that IFN-gamma inhibits cyclin A transcription by modifying co-activators or general transcription factors within the complex that drives transcription of the cyclin A gene...
  2. ncbi Embryonic expression suggests an important role for CRP2/SmLIM in the developing cardiovascular system
    M K Jain
    Cardiovascular Biology Laboratory, Harvard School of Public Health, The Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA
    Circ Res 83:980-5. 1998
    ..These patterns of expression were maintained in the adult animal and suggest an important role for this gene family in the development of smooth and striated muscle...
  3. ncbi Transforming growth factor-beta 1 inhibits cytokine-mediated induction of human metalloelastase in macrophages
    M W Feinberg
    Program of Developmental Cardiovascular Biology, The Department of Medicine, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    J Biol Chem 275:25766-73. 2000
    ..Taken together, MMP-12 is induced by several factors implicated in atherosclerosis. The inhibition of MMP-12 expression by TGF-beta1 suggests that TGF-beta1, acting via Smad3, may promote plaque stability...
  4. ncbi Characterization of the mUBC9-binding sites required for E2A protein degradation
    G S Huggins
    Cardiovascular Biology Laboratory, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Biol Chem 274:28690-6. 1999
    ..Our experiments indicate that the E2A DD mediates E2A protein interactions with the ubiquitin-proteasome system and that the E2A DD is required for metabolism of these widely expressed proteins...
  5. ncbi Molecular cloning and characterization of SmLIM, a developmentally regulated LIM protein preferentially expressed in aortic smooth muscle cells
    M K Jain
    Cardiovascular Biology Laboratory, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    J Biol Chem 271:10194-9. 1996
    ..The down-regulation of SmLIM by phenotypic change in vascular smooth muscle cells suggests that it may be involved in their growth and differentiation...