Richard I Sherwood

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Prospective isolation and global gene expression analysis of definitive and visceral endoderm
    Richard I Sherwood
    Department of Molecular and Cellular Biology, Harvard Stem Cell Institute, Harvard University, 7 Divinity Ave, Cambridge, MA 02138, USA
    Dev Biol 304:541-55. 2007
  2. pmc Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal
    Kathy K Niakan
    Stowers Medical Institute, Harvard University, Cambridge, Massachusetts 02138, USA
    Genes Dev 24:312-26. 2010
  3. pmc Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation
    Alice E Chen
    Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA
    Development 140:675-86. 2013
  4. pmc Transcriptional dynamics of endodermal organ formation
    Richard I Sherwood
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA
    Dev Dyn 238:29-42. 2009
  5. pmc Genetic targeting of the endoderm with claudin-6CreER
    William J Anderson
    Department of Molecular and Cellular Biology, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts 02138, USA
    Dev Dyn 237:504-12. 2008
  6. ncbi request reprint Little evidence for developmental plasticity of adult hematopoietic stem cells
    Amy J Wagers
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Science 297:2256-9. 2002
  7. ncbi request reprint Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle
    Richard I Sherwood
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Cell 119:543-54. 2004
  8. ncbi request reprint Determinants of skeletal muscle contributions from circulating cells, bone marrow cells, and hematopoietic stem cells
    Richard I Sherwood
    Department of Pathology and Developmental Biology, Stanford University School of Medicine, Stanford, California, USA
    Stem Cells 22:1292-304. 2004

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Prospective isolation and global gene expression analysis of definitive and visceral endoderm
    Richard I Sherwood
    Department of Molecular and Cellular Biology, Harvard Stem Cell Institute, Harvard University, 7 Divinity Ave, Cambridge, MA 02138, USA
    Dev Biol 304:541-55. 2007
    ..These results shed light on the mechanism of endoderm formation and should facilitate investigation of endoderm formation from embryonic stem cells...
  2. pmc Sox17 promotes differentiation in mouse embryonic stem cells by directly regulating extraembryonic gene expression and indirectly antagonizing self-renewal
    Kathy K Niakan
    Stowers Medical Institute, Harvard University, Cambridge, Massachusetts 02138, USA
    Genes Dev 24:312-26. 2010
    ..By elaborating the function of Sox17, our results provide insight into how the transcriptional network promoting ES cell self-renewal is interrupted, allowing cellular differentiation...
  3. pmc Functional evaluation of ES cell-derived endodermal populations reveals differences between Nodal and Activin A-guided differentiation
    Alice E Chen
    Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA
    Development 140:675-86. 2013
    ..Our findings underscore the importance of functional cell-type evaluation during stepwise differentiation of stem cells...
  4. pmc Transcriptional dynamics of endodermal organ formation
    Richard I Sherwood
    Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts 02138, USA
    Dev Dyn 238:29-42. 2009
    ..These results contribute to understanding the mechanism of endodermal organogenesis and should assist efforts to replicate this process using pluripotent stem cells...
  5. pmc Genetic targeting of the endoderm with claudin-6CreER
    William J Anderson
    Department of Molecular and Cellular Biology, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts 02138, USA
    Dev Dyn 237:504-12. 2008
    ..Cldn6 null mice are viable and fertile with no obvious phenotypic abnormalities. We also report a lineage analysis of the fate of Cldn6-expressing embryonic cells, which is relevant to the development of the pancreas, lung, and liver...
  6. ncbi request reprint Little evidence for developmental plasticity of adult hematopoietic stem cells
    Amy J Wagers
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Science 297:2256-9. 2002
    ..These data indicate that "transdifferentiation" of circulating HSCs and/or their progeny is an extremely rare event, if it occurs at all...
  7. ncbi request reprint Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle
    Richard I Sherwood
    Department of Pathology, Stanford University School of Medicine, Stanford, CA 94305, USA
    Cell 119:543-54. 2004
    ..Together, these studies describe the clonal isolation of functional adult myogenic progenitors and demonstrate that these cells do not arise from hematopoietic or other bone marrow or circulating precursors...
  8. ncbi request reprint Determinants of skeletal muscle contributions from circulating cells, bone marrow cells, and hematopoietic stem cells
    Richard I Sherwood
    Department of Pathology and Developmental Biology, Stanford University School of Medicine, Stanford, California, USA
    Stem Cells 22:1292-304. 2004
    ..It is not yet clear whether such events represent a normal myogenic pathway or a pathological response to muscle damage...