L M Shaw

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Integrin function in breast carcinoma progression
    L M Shaw
    Dana 601, Beth Israel, Deaconess Medical Center, Boston, Massachusetts 00215, USA
    J Mammary Gland Biol Neoplasia 4:367-76. 1999
  2. ncbi request reprint Integrin laminin receptors and breast carcinoma progression
    A M Mercurio
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Mammary Gland Biol Neoplasia 6:299-309. 2001
  3. pmc Identification of insulin receptor substrate 1 (IRS-1) and IRS-2 as signaling intermediates in the alpha6beta4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion
    L M Shaw
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Mol Cell Biol 21:5082-93. 2001
  4. ncbi request reprint The alpha 6 beta 4 integrin and epithelial cell migration
    A M Mercurio
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts 02115, USA
    Curr Opin Cell Biol 13:541-5. 2001
  5. ncbi request reprint Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells
    R E Bachelder
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Cancer Res 61:5736-40. 2001
  6. ncbi request reprint The metastatic odyssey: the integrin connection
    A M Mercurio
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Surg Oncol Clin N Am 10:313-28, viii-ix. 2001
  7. ncbi request reprint cag+ Helicobacter pylori induce transactivation of the epidermal growth factor receptor in AGS gastric epithelial cells
    S Keates
    Division of Gastroenterology and Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Biol Chem 276:48127-34. 2001

Detail Information

Publications7

  1. ncbi request reprint Integrin function in breast carcinoma progression
    L M Shaw
    Dana 601, Beth Israel, Deaconess Medical Center, Boston, Massachusetts 00215, USA
    J Mammary Gland Biol Neoplasia 4:367-76. 1999
    ..Although this field is still emerging and much remains to be learned, potential integrin-dependent signaling targets have been identified...
  2. ncbi request reprint Integrin laminin receptors and breast carcinoma progression
    A M Mercurio
    Department of Pathology, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Mammary Gland Biol Neoplasia 6:299-309. 2001
    ..Recent work by our group and others on mechanisms of breast carcinoma invasion and survival that are influenced by the alpha6 integrins are discussed...
  3. pmc Identification of insulin receptor substrate 1 (IRS-1) and IRS-2 as signaling intermediates in the alpha6beta4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion
    L M Shaw
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Mol Cell Biol 21:5082-93. 2001
    ..Taken together, these results imply a key role for the IRS proteins in the alpha6beta4-dependent promotion of carcinoma invasion...
  4. ncbi request reprint The alpha 6 beta 4 integrin and epithelial cell migration
    A M Mercurio
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center, and Harvard Medical School, Boston, Massachusetts 02115, USA
    Curr Opin Cell Biol 13:541-5. 2001
    ....
  5. ncbi request reprint Vascular endothelial growth factor is an autocrine survival factor for neuropilin-expressing breast carcinoma cells
    R E Bachelder
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Cancer Res 61:5736-40. 2001
    ..The identification of this VEGF autocrine signaling pathway has important implications for tumor metastasis and therapeutic intervention...
  6. ncbi request reprint The metastatic odyssey: the integrin connection
    A M Mercurio
    Division of Cancer Biology and Angiogenesis, Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    Surg Oncol Clin N Am 10:313-28, viii-ix. 2001
    ..Numerous studies have implicated these integrins in cancer progression and have provided a rationale for studying the mechanistic basis of their contribution to aggressive disease...
  7. ncbi request reprint cag+ Helicobacter pylori induce transactivation of the epidermal growth factor receptor in AGS gastric epithelial cells
    S Keates
    Division of Gastroenterology and Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Biol Chem 276:48127-34. 2001
    ..Transactivation of gastric epithelial cell EGF receptors may be instrumental in regulating both proliferative and inflammatory responses induced by cag+ H. pylori infection...