Affiliation: Harvard University
- The demise of ipecacMichael Shannon
Program in Medical Toxicology, Division of Emergency Medicine, Children s Hospital Harvard Medical School, Boston, MA 02115, USA
Pediatrics 112:1180-1. 2003
- Severe lead poisoning in pregnancyMichael Shannon
Pediatric Environmental Health Center and the Division of Emergency Medicine, Children s Hospital, Harvard Medical School, Boston, Mass 02115, USA
Ambul Pediatr 3:37-9. 2003..The scope and consequences of severe lead poisoning in pregnancy (blood lead level > or =45 microg/dL) have not been well characterized...
- Children's environmental health: one year in a pediatric environmental health specialty unitMichael Shannon
Division of Emergency Medicine and the Program in Clinical Toxicology, Children s Hospital, Boston, Mass 02115, USA
Ambul Pediatr 3:53-6. 2003..This descriptive study profiles the children seen in one unit of this program...
- Glass thermometer injuries: it is not just about the mercuryNadine Aprahamian
Division of Emergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
Pediatr Emerg Care 25:645-7. 2009..Once broken, however, there is the dual hazard of broken glass and exposure to mercury. Previous studies have focused only on the mercury hazard rather than injuries related to thermometer glass...
- The serotonin syndromeEdward W Boyer
Division of Medical Toxicology, Department of Emergency Medicine, University of Massachusetts, Worcester, USA
N Engl J Med 352:1112-20. 2005
- Effects of 4-methylpyrazole on ethanol neurobehavioral toxicity in CD-1 miceAna Maria Páez
Division of Emergency Medicine and the Program in Clinical Pharmacology Toxicology, Children s Hospital Boston, Harvard Medical School, Boston, MA, USA
Acad Emerg Med 11:820-6. 2004..This was a study to determine whether ADH blockade with 4-MP prolongs ethanol neurobehavioral toxicity in a murine model...
- Efficacy of an educational Web site for educating physicians about bioterrorismSarita Chung
Children s Hospital Boston, Department of Pediatrics, Harvard Medical School, Boston, MA 02215, USA
Acad Emerg Med 11:143-8. 2004..To determine whether a Web-based educational intervention improves emergency physicians' knowledge about bioterrorism and to survey physicians' knowledge and sources of information on bioterrorism...
- Building a trauma center and system in Tuscany, ItalyKevin M Ban
Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, One Deaconess Road, West CC2, 2nd Floor, Boston, MA 02215, USA
Intern Emerg Med 1:302-4. 2006..Systems measurements will be achieved through a comprehensive quality improvement and risk management program. Ultimately, all Tuscan regional pediatric major trauma will be consolidated at the Meyer Pediatric Hospital in Florence...
- The Internet and psychoactive substance use among innovative drug usersEdward W Boyer
Department of Emergency Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
Pediatrics 115:302-5. 2005..The Internet contains an extraordinary amount of information on the recreational use of psychoactive substances. We investigated the effect of the Internet on the drug-use knowledge, attitudes, and behaviors of adolescents...
- Polymorphism of the ADRB2 gene and response to inhaled beta- agonists in children with asthma: a meta-analysisYaron Finkelstein
Clinical Pharmacology Unit, and Division of Emergency Medicine, Boston Children s Hospital, Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
J Asthma 46:900-5. 2009....
- Holiday ornament-related injuries in childrenAmir Kimia
Division of Emergency Medicine, Harvard Medical School, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
Pediatr Emerg Care 25:819-22. 2009..Holiday ornament injuries in children have not been well documented in the medical literature. Our aim was to investigate the patterns of injuries sustained from these ornaments as a first measure toward prevention...
- Bench to bedside: Pharmacogenomics, adverse drug interactions, and the cytochrome P450 systemRishi Sikka
Department of Emergency Medicine, Boston University School of Medicine, Boston, MA, USA
Acad Emerg Med 12:1227-35. 2005..These enzymes, CYP3A4, CYP2D6, CYP2C9, CYP2C19, CYP2E1, and CYP1A2, are reviewed with regard to their phenotypic variation in the population and the resulting clinical and therapeutic implications...
- Reuniting children with their families during disasters: a proposed plan for greater successSarita Chung
The Center for Biopreparedness, Division of Emergency Medicine, Children s Hospital Boston, USA
Am J Disaster Med 2:113-7. 2007..Additional advanced features of such a system will be explored. If successful, the use of such a system would address an important unmet need in pediatric emergency preparedness...
- Emergency care for children in pediatric and general emergency departmentsFlorence T Bourgeois
Division of Emergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
Pediatr Emerg Care 23:94-102. 2007..We examine the pediatric emergency department (ED) population and their clinical course in pediatric versus general EDs and identify potential factors contributing to differences in performance metrics between the 2 ED settings...
- Comparative analysis of zinc protoporphyrin and blood lead levels in lead-exposed Andean childrenS Allen Counter
Department of Neurology, Harvard Medical School The Biological Laboratories, Cambridge, MA 02138, USA
Clin Biochem 40:787-92. 2007..The objective of this study was to investigate the zinc protoporphyrin/heme ratio (ZPP/heme) as a biomarker for chronic lead (Pb) poisoning in children with a history of high Pb exposure...
- Transient psychosis in an immune-competent patient after oral trimethoprim-sulfamethoxazole administrationMohsen Saidinejad
Division of Emergency Medicine Program in Medical Toxicology, Massachusetts and Rhode Island Poison Control Center, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
Pediatrics 115:e739-41. 2005..Central nervous system toxicity is very rare; when reported, it has been in an immune-compromised or an elderly patient...
- Environmental evaluation of a child with developmental disabilityJaved Hussain
Pediatric Environmental Health Center, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
Pediatr Clin North Am 54:47-62, viii. 2007..A detailed environmental history and physical examination may help clarify whether there is a plausible relationship between an environmental toxicant and a child's disability...
- Association of race/ethnicity with emergency department wait timesCatherine A James
Division of Emergency Medicine, Children s Hospital Boston, and Department of Pediatrics, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA
Pediatrics 115:e310-5. 2005..To determine whether wait times for children treated in emergency departments (EDs) nationally are associated with patient race/ethnicity...
- 4-methylpyrazole decreases 1,4-butanediol toxicity by blocking its in vivo biotransformation to gamma-hydroxybutyric acidLawrence S Quang
Division of Emergency Medicine, Children s Hospital Boston Harvard Medical School, Boston, Massachusetts, USA
Ann N Y Acad Sci 1025:528-37. 2004..In this murine model of 1,4-BD overdose, 4-MP conferred antidotal effects by inhibiting alcohol dehydrogenase-mediated biotransformation of 1,4-BD to gamma-hydroxybutyric acid...
- Retropharyngeal cellulitis in a 5-week-old infantFlorence T Bourgeois
Department of Medicine, Children s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Pediatrics 109:E51. 2002..We report the case of a 5-week-old infant who had sudden irritability and was found to have retropharyngeal cellulitis caused by group B Streptococcus...
- Enzyme and receptor antagonists for preventing toxicity from the gamma-hydroxybutyric acid precursor 1,4-butanediol in CD-1 miceLawrence S Quang
Division of Emergency Medicine, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
Ann N Y Acad Sci 965:461-72. 2002..However, pretreatment of CD-1 mice with NCS-382 alone produced prolonged failure of the rotarod test, an unexpected synergistic effect with 1,4-BD and presumably GHB, which has not previously been demonstrated...
- Management of calcium channel antagonist overdoseSteven D Salhanick
Children s Hospital, Boston, Massachusetts 02115, USA
Drug Saf 26:65-79. 2003..Charcoal should be given to the asymptomatic patient with a history of calcium channel antagonist overdose...
- Poisoning from a dietary supplement administered during hospitalizationEdward W Boyer
Department of Emergency Medicine, University of Massachusetts, Worcester, Massachusetts 01655, USA
Pediatrics 109:E49. 2002..We present the case of a child who received a DS on a daily basis as an outpatient, continued its use after admission to the hospital, and became poisoned by it during his hospitalization...
- Adult patient visits to children's hospital emergency departmentsFlorence T Bourgeois
Department of Medicine Division of Emergency Medicine, Children s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
Pediatrics 111:1268-72. 2003..In recent years visits by adults to CHEDs appear to have increased...
- Succimer (meso-2,3-dimercaptosuccinic acid (DMSA)) treatment of Andean children with environmental lead exposureS Allen Counter
Department of Neurology, Harvard Medical School, Biological Laboratories, Harvard University, 16 Divinity Avenue, Cambridge, Massachusetts 02138, USA
Int J Occup Environ Health 9:164-8. 2003....
- Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 30-2003. A 21-year-old man with sudden alteration of mental statusDavid N Tancredi
Department of Emergency Medicine, Massachusetts General Hospital, Boston, USA
N Engl J Med 349:1267-75. 2003
- Laboratory diagnosis of 1,4-BD and GHB overdose by routine urine organic acid analysisLawrence S Quang
Clin Toxicol (Phila) 43:321-3. 2005
- Ondansetron decreases vomiting associated with acute gastroenteritis: a randomized, controlled trialJohn J Reeves
Department of Pediatric Emergency Medicine, University Medical Center, Las Vegas, Nevada 89102, USA
Pediatrics 109:e62. 2002..The objective of this study was to evaluate the efficacy of ondansetron for the treatment of vomiting associated with acute gastroenteritis in children...
- Diagnosis of acute appendicitis in children using a clinical practice guidelineDouglas S Smink
Department of Surgery, Children s Hospital Boston, Boston, MA 02115, USA
J Pediatr Surg 39:458-63; discussion 458-63. 2004..The authors sought to determine surgical outcomes and diagnostic accuracy in the CPG period...
- Which drug tests in medical emergencies?Edward W Boyer
Clin Chem 49:353-4. 2003
- d-Penicillamine Chelation in lead-poisoned Children - A Phase ll/lll TrialMichael Shannon; Fiscal Year: 2007..This trial may also provide a basis for examining the drug's efficacy in improving neurodevelopment outcome in children exposed to harmful amounts of lead. ..