Research Topics
| Soko SetoguchiSummaryAffiliation: Harvard University Country: USA Publications
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Detail Information
Publications
Repeated hospitalizations predict mortality in the community population with heart failureSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02130, USA
Am Heart J 154:260-6. 2007..The impact of repeated heart failure (HF) hospitalization on mortality has not been studied for a large community population with HF. We aimed to characterize survival of patients in relation to the number of HF hospitalizations...
Improvements in long-term mortality after myocardial infarction and increased use of cardiovascular drugs after discharge: a 10-year trend analysisSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02120, USA
J Am Coll Cardiol 51:1247-54. 2008..We sought to assess the relationship between increasing use of cardiovascular medications and trends in long-term prognosis after myocardial infarction (MI) in the elderly...
Prevalence of atrial fibrillation and warfarin use in older patients receiving hemodialysisWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Nephrol 25:341-53. 2012..Little is known about the use of warfarin in hemodialysis (HD) patients with atrial fibrillation (AF). We studied temporal trends of AF among older HD patients, and of warfarin use among those with AF...
Tumor necrosis factor-alpha antagonist use and heart failure in elderly patients with rheumatoid arthritisSoko Setoguchi
Divisions of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard MedicalSchool, Boston, MA 02130, USA
Am Heart J 156:336-41. 2008..Although TNFAs had significant benefits in treating rheumatoid arthritis (RA), little is known whether the drugs pose an increased risk of HF in older patients with RA...
Immunosuppressive medications and hospitalization for cardiovascular events in patients with rheumatoid arthritisDaniel H Solomon
Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Arthritis Rheum 54:3790-8. 2006..This study was undertaken to investigate the effects of various immunosuppressive medications on the risk of cardiovascular events among a group of older patients with RA...
Anti-tumor necrosis factor alpha therapy and the risk of serious bacterial infections in elderly patients with rheumatoid arthritisSebastian Schneeweiss
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
Arthritis Rheum 56:1754-64. 2007..To assess the association between the initiation of anti-tumor necrosis factor alpha (anti-TNFalpha) therapy and the risk of serious bacterial infections in routine care...
Effectiveness and safety of warfarin initiation in older hemodialysis patients with incident atrial fibrillationWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Clin J Am Soc Nephrol 6:2662-8. 2011..Although generally recommended in atrial fibrillation (AF) patients, the effectiveness and safety of oral anticoagulation in dialysis patients with AF is unknown...
Trends in adherence to secondary prevention medications in elderly post-myocardial infarction patientsNiteesh K Choudhry
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02120, USA
Pharmacoepidemiol Drug Saf 17:1189-96. 2008..Poor levels of medication adherence for patients with coronary heart disease (CHD) have been documented but it is unclear whether adherence has improved over time...
Potential causes of higher mortality in elderly users of conventional and atypical antipsychotic medicationsSoko Setoguchi
Department of Medicine, Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, USA
J Am Geriatr Soc 56:1644-50. 2008....
Ten-year trends of cardiovascular drug use after myocardial infarction among community-dwelling persons > or =65 years of ageSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 100:1061-7. 2007..The underuse of statins and BBs was marked in black patients and did not improve over time...
Subgroup analyses to determine cardiovascular risk associated with nonsteroidal antiinflammatory drugs and coxibs in specific patient groupsDaniel H Solomon
Brigham and Women s Hospital, 1620 Tremont Street, Boston, MA 02120, USA
Arthritis Rheum 59:1097-104. 2008..There is substantial concern regarding the potential cardiovascular adverse effects of selective coxibs and nonselective NSAIDs, but many patients with arthritis experience important clinical benefits from these agents...
Associations of kidney function with cardiovascular medication use after myocardial infarctionWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02120, USA
Clin J Am Soc Nephrol 3:1415-22. 2008..It is unknown whether adherence to recommended medications after myocardial infarction (MI) differs by kidney function...
Agreement of diagnosis and its date for hematologic malignancies and solid tumors between medicare claims and cancer registry dataSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Cancer Causes Control 18:561-9. 2007..However, linkage between cancer registry and claims data including pharmacy-dispensing information is not always available. We examined the accuracy of claims-based definitions of incident cancers and their date of diagnosis...
Hospice, opiates, and acute care service use among the elderly before death from heart failure or cancerSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
Am Heart J 160:139-44. 2010..Advances in heart failure (HF) treatments have prolonged survival, but more patients die of HF than of any type of cancer. Little is known about the current practice in end-of-life (EOL) care in HF...
Maximum potential benefit of implantable defibrillators in preventing sudden death after hospital admission because of heart failureSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02130, USA
CMAJ 180:611-6. 2009..However, criteria to identify those who would benefit most from this therapy are lacking. We assessed the maximum potential benefit of preventing sudden death in patients with repeated hospital admissions because of heart failure...
Propranolol and the risk of hospitalized myopathy: translating chemical genomics findings into population-level hypothesesSoko Setoguchi
Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Am Heart J 159:428-33. 2010..We tested this hypothesis in a large population to assess whether (1) propranolol use is associated with an increased risk of myopathy and (2) the concurrent use of propranolol with a statin may further increase risk of myopathy...
Trends in the use and outcomes of implantable cardioverter-defibrillators in patients undergoing dialysis in the United StatesDavid M Charytan
Renal Division, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Am J Kidney Dis 58:409-17. 2011..Sudden cardiac death constitutes the leading cause of death in patients receiving dialysis. Little is known about the trends in implantable cardioverter-defibrillator (ICD) use and the outcomes of such device placement...
Use of disease-modifying antirheumatic drugs during pregnancy and risk of preeclampsiaKristin Palmsten
Harvard School of Public Health, Boston, Massachusetts, USA
Arthritis Care Res (Hoboken) 64:1730-8. 2012....
Assessing residual confounding of the association between antipsychotic medications and risk of death using survey dataSebastian Schneeweiss
Division of Pharmacoepidemiology and Pharmacoeconomics, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts, USA
CNS Drugs 23:171-80. 2009..Nonrandomised studies on the causal effects of psychotropic medications may be biased by patient characteristics that are not fully adjusted...
Comparison of prospective and retrospective indicators of the quality of end-of-life cancer careSoko Setoguchi
Division of General Medicine and Primary Care, Brigham and Women s Hospital, Boston, MA 02120 1613, USA
J Clin Oncol 26:5671-8. 2008..To compare prospectively and retrospectively defined benchmarks for the quality of end-of-life care, including a novel indicator for the use of opiate analgesia...
Gender differences in the management and prognosis of myocardial infarction among patients > or = 65 years of ageSoko Setoguchi
Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Am J Cardiol 101:1531-6. 2008..Men, especially those aged > or =75 years, however, had worse short- and long-term prognoses compared with women of a similar age. The mortality was highest and the gender effect was more pronounced during the MI hospitalizations...
Validity of claims-based definitions of left ventricular systolic dysfunction in Medicare patientsQian Li
Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
Pharmacoepidemiol Drug Saf 20:700-8. 2011..We aimed to assess the validity of claims data-based definitions of systolic dysfunction (SD)...
Risk of death associated with the use of conventional versus atypical antipsychotic drugs among elderly patientsSebastian Schneeweiss
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 021205, USA
CMAJ 176:627-32. 2007..We assessed the short-term mortality in a population-based cohort of elderly people in British Columbia who were prescribed conventional and atypical antipsychotic medications...
Evaluating uses of data mining techniques in propensity score estimation: a simulation studySoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02130, USA
Pharmacoepidemiol Drug Saf 17:546-55. 2008....
Long-term trends of angiotensin-converting enzyme inhibitor and angiotensin-receptor blocker use after heart failure hospitalization in community-dwelling seniorsSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02120, United States
Int J Cardiol 125:172-7. 2008..Little is known about recent trends in the use of ACEI/ARB in community-dwelling seniors...
Algorithms to estimate the beginning of pregnancy in administrative databasesAndrea V Margulis
Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
Pharmacoepidemiol Drug Saf 22:16-24. 2013..Therefore, we sought to develop and validate algorithms to estimate the gestational age at birth using information available in these databases...
Elevated risk of preeclampsia in pregnant women with depression: depression or antidepressants?Kristin Palmsten
Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
Am J Epidemiol 175:988-97. 2012..24) for TCA monotherapy. Study results suggest that women who use antidepressants during pregnancy, especially SNRIs and TCAs, have an elevated risk of preeclampsia. These associations may reflect drug effects or more severe depression...
Comparison of cardiovascular outcomes in elderly patients with diabetes who initiated rosiglitazone vs pioglitazone therapyWolfgang C Winkelmayer
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, 1620 Tremont St, Ste 3030, Boston, MA 02120, USA
Arch Intern Med 168:2368-75. 2008..We compared cardiovascular outcomes and mortality between patients initiating pioglitazone vs rosiglitazone therapy...
Statins and the risk of lung, breast, and colorectal cancer in the elderlySoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont St, Suite 3030, Boston, MA 02130, USA
Circulation 115:27-33. 2007..Long-term statin users tend to be healthier, less frail, and more adherent to therapy than nonusers, however. This could explain such apparent "protective" effects...
Tumor necrosis factor alpha antagonist use and cancer in patients with rheumatoid arthritisSoko Setoguchi
Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02130, USA
Arthritis Rheum 54:2757-64. 2006..This study was undertaken to estimate the association between treatment with biologic disease-modifying antirheumatic drugs (DMARDs) and development of cancer in patients with RA...
Follow-up of patients with new cardiovascular implantable electronic devices: are experts' recommendations implemented in routine clinical practice?Sana M Al-Khatib
Duke Clinical Research Institute, Department of Medicine, Duke University School of Medicine, Durham, NC 27715, USA
Circ Arrhythm Electrophysiol 6:108-16. 2013..A 2008 expert consensus statement outlined the minimum frequency of follow-up of patients with cardiovascular implantable electronic devices (CIEDs)...
Psychotropic medication use for behavioral symptoms of dementiaPhilip S Wang
Department of Psychiatry, Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women s Hospital, Harvard Medical School, 1620 Tremont Street, Suite 3030, Boston, MA 02120, USA
Curr Neurol Neurosci Rep 6:490-5. 2006..Also, although various psychotropic medications used for behavioral disturbances in dementia patients may be somewhat effective, they have been increasingly associated with important safety risks...
Bone mineral density in older adult patients with rheumatoid arthritis: an analysis of NHANES IIIMitsuyo Kinjo
Teine Keijinkai Hospital, Teine ku Sapporo city, Japan
J Rheumatol 34:1971-5. 2007..We examined the relationship between BMD and RA in a representative US population-based sample from the Third National Health and Nutrition Examination Survey (NHANES III: 1988-1994)...
Treatment of older adult patients diagnosed with rheumatoid arthritis: improved but not optimalGabriela Schmajuk
Stanford University, Palo Alto, California, USA
Arthritis Rheum 57:928-34. 2007..Our objective was to determine the rate and predictors of DMARD use in a cohort of elderly patients with RA...
Ventricular arrhythmias and cerebrovascular events in the elderly using conventional and atypical antipsychotic medicationsPhilip S Wang
J Clin Psychopharmacol 27:707-10. 2007
Mortality and adherence to pharmacotherapy after acute myocardial infarctionMitsuyo Kinjo
JAMA 297:1877-8; author reply 1878. 2007
Tetrahydrobiopterin improves impaired endothelium-dependent forearm vasodilation in patients with heart failureSoko Setoguchi
Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
J Cardiovasc Pharmacol 39:363-8. 2002..The administration of BH(4) did not alter the baseline FBF in either group. These results suggest that an acute administration of BH(4 ) improves endothelium-dependent forearm vasodilation in patients with CHF...
