J M Serrador

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Dynamic cerebral autoregulation after intracerebral hemorrhage: A case-control study
    Kazuma Nakagawa
    Neuroscience Institute, The Queen s Medical Center, Honolulu, Hawaii, USA
    BMC Neurol 11:108. 2011
  2. pmc Vestibular effects on cerebral blood flow
    Jorge M Serrador
    Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA
    BMC Neurosci 10:119. 2009
  3. ncbi request reprint Cerebral pressure-flow relations in hypertensive elderly humans: transfer gain in different frequency domains
    Jorge M Serrador
    Hebrew Rehabilitation Center for Aged, Beth Israel Deaconess Medical Center Gerontology Palmer 117, One Deaconess Road, Boston, MA 02215, USA
    J Appl Physiol 98:151-9. 2005
  4. pmc Cerebral hypoperfusion precedes nausea during centrifugation
    Jorge M Serrador
    Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Aviat Space Environ Med 76:91-6. 2005
  5. ncbi request reprint Cerebral blood flow during orthostasis: role of arterial CO2
    J M Serrador
    Division on Aging, Harvard Medical School, Beth Israel Deaconess Medical Center, One Deaconess Rd, Palmer 117, Boston, MA 02215, USA
    Am J Physiol Regul Integr Comp Physiol 290:R1087-93. 2006
  6. pmc Loss of otolith function with age is associated with increased postural sway measures
    Jorge M Serrador
    Harvard Medical School, Boston, MA, United States Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neurosci Lett 465:10-5. 2009
  7. pmc The sit-to-stand technique for the measurement of dynamic cerebral autoregulation
    Farzaneh A Sorond
    Department of Neurology, Stroke Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Ultrasound Med Biol 35:21-9. 2009
  8. pmc Cerebrovascular hemodynamics, gait, and falls in an elderly population: MOBILIZE Boston Study
    F A Sorond
    Department of Neurology, Stroke Division, Brigham and Women s Hospital, 45 Francis St, Boston, MA 02115, USA
    Neurology 74:1627-33. 2010
  9. ncbi request reprint Effect of acute exposure to hypergravity (GX vs. GZ) on dynamic cerebral autoregulation
    J M Serrador
    Cerebral Blood Flow Research Lab, School of Kinesiology, The University of Western Ontario, London, Ontario, Canada N6A 3K7
    J Appl Physiol 91:1986-94. 2001
  10. pmc Enhanced vasoreactivity and its response to antihypertensive therapy in hypertensive elderly women
    Lewis A Lipsitz
    Hebrew SeniorLife, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Hypertension 47:377-83. 2006

Research Grants

  1. VESTIBULAR-CEREBROVASCULAR INTERACTIONS IN HUMANS
    Jorge Serrador; Fiscal Year: 2004

Collaborators

Detail Information

Publications16

  1. pmc Dynamic cerebral autoregulation after intracerebral hemorrhage: A case-control study
    Kazuma Nakagawa
    Neuroscience Institute, The Queen s Medical Center, Honolulu, Hawaii, USA
    BMC Neurol 11:108. 2011
    ..Dynamic cerebral autoregulation after intracerebral hemorrhage (ICH) remains poorly understood. We performed a case-control study to compare dynamic autoregulation between ICH patients and healthy controls...
  2. pmc Vestibular effects on cerebral blood flow
    Jorge M Serrador
    Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA
    BMC Neurosci 10:119. 2009
    ..In this study, we tested the hypothesis that stimulation of the vestibular system, specifically the otoliths organs, would result in changes in cerebral blood flow...
  3. ncbi request reprint Cerebral pressure-flow relations in hypertensive elderly humans: transfer gain in different frequency domains
    Jorge M Serrador
    Hebrew Rehabilitation Center for Aged, Beth Israel Deaconess Medical Center Gerontology Palmer 117, One Deaconess Road, Boston, MA 02215, USA
    J Appl Physiol 98:151-9. 2005
    ..Pressure regulation of cerebral blood flow is unrelated to cerebrovascular reactivity to CO(2)...
  4. pmc Cerebral hypoperfusion precedes nausea during centrifugation
    Jorge M Serrador
    Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Aviat Space Environ Med 76:91-6. 2005
    ..The goal of this work was to determine if changes in cerebral blood flow precede the development of nausea in subjects susceptible to motion sickness...
  5. ncbi request reprint Cerebral blood flow during orthostasis: role of arterial CO2
    J M Serrador
    Division on Aging, Harvard Medical School, Beth Israel Deaconess Medical Center, One Deaconess Rd, Palmer 117, Boston, MA 02215, USA
    Am J Physiol Regul Integr Comp Physiol 290:R1087-93. 2006
    ..Furthermore, the reduction in Pa(CO(2)) did not fully explain the decrease in CFV throughout HUT. These data suggest that factors in addition to a reduction in Pa(CO(2)) play a role in the CBF response to orthostatic stress...
  6. pmc Loss of otolith function with age is associated with increased postural sway measures
    Jorge M Serrador
    Harvard Medical School, Boston, MA, United States Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neurosci Lett 465:10-5. 2009
    ..These data suggest a role for loss of otolith function in contributing to fall risk in the elderly. Further prospective, longitudinal studies are necessary to confirm these findings...
  7. pmc The sit-to-stand technique for the measurement of dynamic cerebral autoregulation
    Farzaneh A Sorond
    Department of Neurology, Stroke Division, Brigham and Women s Hospital, Boston, MA 02115, USA
    Ultrasound Med Biol 35:21-9. 2009
    ..The sit-to-stand technique appears to be a suitable measure of individual ARI values for inferring dynamic cerebral autoregulation...
  8. pmc Cerebrovascular hemodynamics, gait, and falls in an elderly population: MOBILIZE Boston Study
    F A Sorond
    Department of Neurology, Stroke Division, Brigham and Women s Hospital, 45 Francis St, Boston, MA 02115, USA
    Neurology 74:1627-33. 2010
    ..To determine whether alterations in cerebral blood flow regulation are associated with slow gait speed and falls in community-dwelling elderly individuals...
  9. ncbi request reprint Effect of acute exposure to hypergravity (GX vs. GZ) on dynamic cerebral autoregulation
    J M Serrador
    Cerebral Blood Flow Research Lab, School of Kinesiology, The University of Western Ontario, London, Ontario, Canada N6A 3K7
    J Appl Physiol 91:1986-94. 2001
    ..We speculate that this leftward shift may have been due to vestibular activation (especially during +GX) or potentially to an adaptation to reduced cerebral perfusion pressure during +GZ...
  10. pmc Enhanced vasoreactivity and its response to antihypertensive therapy in hypertensive elderly women
    Lewis A Lipsitz
    Hebrew SeniorLife, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Hypertension 47:377-83. 2006
    ..These results highlight the beneficial effects of antihypertensive therapy on the systemic vasculature, particularly for elderly women in whom enhanced vasoreactivity may contribute to excessive cardiovascular morbidity and mortality...
  11. pmc Cardiovascular, inflammatory, and metabolic consequences of sleep deprivation
    Janet M Mullington
    Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School Division of Cardiology, Boston Medical Center, Boston University School of Medicine, Boston, MA, USA
    Prog Cardiovasc Dis 51:294-302. 2009
    ..These studies show that insufficient sleep alters established cardiovascular risk factors in a direction that is known to increase the risk of cardiac morbidity...
  12. pmc Cerebral blood flow regulation during cognitive tasks: effects of healthy aging
    Farzaneh A Sorond
    Department of Neurology, Stroke Division, Brigham and Women s Hospital, Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, MA 02115, USA
    Cortex 44:179-84. 2008
    ..Our data suggest that there is differential blood flow increase in the ACA and PCA in young versus elderly subjects during cognitive tasks...
  13. pmc Autoregulation in the posterior circulation is altered by the metabolic state of the visual cortex
    Kazuma Nakagawa
    Department of Neurology, Stroke Division, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Stroke 40:2062-7. 2009
    ..We examined the role of cerebral vasodilation caused by metabolic activation (ie, visual stimulus) on autoregulatory characteristics in the 2 vascular territories...
  14. pmc Regional cerebral autoregulation during orthostatic stress: age-related differences
    Farzaneh A Sorond
    Brigham and Women s Hospital, Neurology Stroke Division, 45 Francis St, Boston, MA 02115, USA
    J Gerontol A Biol Sci Med Sci 60:1484-7. 2005
    ....
  15. doi request reprint Elderly women regulate brain blood flow better than men do
    Brian M Deegan
    Electrical and Electronic Engineering, School of Engineering and Informatics, NUI Galway, University Road, Galway, Ireland
    Stroke 42:1988-93. 2011
    ..This study was designed to determine whether cerebral autoregulation, assessed using transcranial Doppler ultrasound, is more effective in elderly females than in males...
  16. ncbi request reprint Head position modifies cerebrovascular response to orthostatic stress
    Timothy D Wilson
    Neurovascular Research Laboratory, The University of Western Ontario, Thames Hall 3110, London, Canada N6A 3K7
    Brain Res 961:261-8. 2003
    ..05) during LBNP. These results suggest that the vestibular system may affect cerebrovascular tone during simulated postural stress by either constriction or dilation, depending on the vestibular stimulus...

Research Grants1

  1. VESTIBULAR-CEREBROVASCULAR INTERACTIONS IN HUMANS
    Jorge Serrador; Fiscal Year: 2004
    ..This work may lead to new methods to diagnose those at risk for falls, as well as ways to train the vestibular system to minimize cerebral hypo-perfusion, syncope, and falls in the elderly. ..