Jorge Sepulcre

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi request reprint Integration of visual and motor functional streams in the human brain
    Jorge Sepulcre
    Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA Athinioula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA Electronic address
    Neurosci Lett 567:68-73. 2014
  2. pmc In vivo characterization of the early states of the amyloid-beta network
    Jorge Sepulcre
    Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Brain 136:2239-52. 2013
  3. pmc Stepwise connectivity of the modal cortex reveals the multimodal organization of the human brain
    Jorge Sepulcre
    Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Neurosci 32:10649-61. 2012
  4. pmc Network assemblies in the functional brain
    Jorge Sepulcre
    Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Curr Opin Neurol 25:384-91. 2012
  5. pmc Modeling the effector - regulatory T cell cross-regulation reveals the intrinsic character of relapses in Multiple Sclerosis
    Nieves Velez de Mendizabal
    Division of Neurosciences, CIMA University of Navarra, Avenida Pio XII 55, 31008 Pamplona, Spain
    BMC Syst Biol 5:114. 2011
  6. pmc The organization of local and distant functional connectivity in the human brain
    Jorge Sepulcre
    Howard Hughes Medical Institute, Cambridge, Massachusetts, United States of America
    PLoS Comput Biol 6:e1000808. 2010
  7. pmc Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease
    Randy L Buckner
    Department of Psychology and Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138, USA
    J Neurosci 29:1860-73. 2009
  8. pmc The dynamics of cortical and hippocampal atrophy in Alzheimer disease
    Mert R Sabuncu
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, 02129, USA
    Arch Neurol 68:1040-8. 2011
  9. pmc Individual variability in functional connectivity architecture of the human brain
    Sophia Mueller
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuron 77:586-95. 2013
  10. pmc The organization of the human cerebral cortex estimated by intrinsic functional connectivity
    B T Thomas Yeo
    Harvard University, Department of Psychology, Center for Brain Science, Cambridge, MA 02138, USA
    J Neurophysiol 106:1125-65. 2011

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Integration of visual and motor functional streams in the human brain
    Jorge Sepulcre
    Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA Athinioula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA Electronic address
    Neurosci Lett 567:68-73. 2014
    ..Our results show that motor and visual connectivity merge in a multimodal integration network that links together perception, action and cognition in the human functional connectome. ..
  2. pmc In vivo characterization of the early states of the amyloid-beta network
    Jorge Sepulcre
    Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Brain 136:2239-52. 2013
    ....
  3. pmc Stepwise connectivity of the modal cortex reveals the multimodal organization of the human brain
    Jorge Sepulcre
    Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Neurosci 32:10649-61. 2012
    ..We identify the large-scale multimodal integration network and essential connectivity axes for perceptual integration in the human brain...
  4. pmc Network assemblies in the functional brain
    Jorge Sepulcre
    Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Curr Opin Neurol 25:384-91. 2012
    ..This review focuses on recent advances in functional connectivity MRI and renewed interest in studying the large-scale functional network assemblies in the brain. We also consider some methodological aspects of graph theoretical analysis...
  5. pmc Modeling the effector - regulatory T cell cross-regulation reveals the intrinsic character of relapses in Multiple Sclerosis
    Nieves Velez de Mendizabal
    Division of Neurosciences, CIMA University of Navarra, Avenida Pio XII 55, 31008 Pamplona, Spain
    BMC Syst Biol 5:114. 2011
    ..g. failure in central tolerance, activation by pathogens) that are able to trigger the immune system...
  6. pmc The organization of local and distant functional connectivity in the human brain
    Jorge Sepulcre
    Howard Hughes Medical Institute, Cambridge, Massachusetts, United States of America
    PLoS Comput Biol 6:e1000808. 2010
    ..We discuss the implications of these observations and applications of the present method for exploring normal and atypical brain function...
  7. pmc Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease
    Randy L Buckner
    Department of Psychology and Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138, USA
    J Neurosci 29:1860-73. 2009
    ....
  8. pmc The dynamics of cortical and hippocampal atrophy in Alzheimer disease
    Mert R Sabuncu
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, 02129, USA
    Arch Neurol 68:1040-8. 2011
    ..To characterize rates of regional Alzheimer disease (AD)-specific brain atrophy across the presymptomatic, mild cognitive impairment, and dementia stages...
  9. pmc Individual variability in functional connectivity architecture of the human brain
    Sophia Mueller
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuron 77:586-95. 2013
    ..Our findings have potential implications for understanding brain evolution and development, guiding intervention, and interpreting statistical maps in neuroimaging...
  10. pmc The organization of the human cerebral cortex estimated by intrinsic functional connectivity
    B T Thomas Yeo
    Harvard University, Department of Psychology, Center for Brain Science, Cambridge, MA 02138, USA
    J Neurophysiol 106:1125-65. 2011
    ..We conclude by discussing the organization of these large-scale cerebral networks in relation to monkey anatomy and their potential evolutionary expansion in humans to support cognition...
  11. pmc Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden
    Alexander Drzezga
    Department of Radiology, Massachusetts General Hospital and Harvard University Medical School, Boston, MA 02114, USA
    Brain 134:1635-46. 2011
    ....
  12. pmc Functional-anatomic fractionation of the brain's default network
    Jessica R Andrews-Hanna
    Department of Psychology and Center for Brain Science, Harvard University, Cambridge, MA 02138, USA
    Neuron 65:550-62. 2010
    ..During certain experimentally directed and spontaneous acts of future-oriented thought, these dissociated components are simultaneously engaged, presumably to facilitate construction of mental models of personally significant events...
  13. pmc Evidence from intrinsic activity that asymmetry of the human brain is controlled by multiple factors
    Hesheng Liu
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 106:20499-503. 2009
    ..These findings show the feasibility of measuring brain asymmetry using intrinsic activity fluctuations and suggest that multiple genetic or environmental mechanisms control cerebral lateralization...
  14. pmc Localization of focal epileptic discharges using functional connectivity magnetic resonance imaging
    Steven M Stufflebeam
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    J Neurosurg 114:1693-7. 2011
    ..The object of this study was to investigate whether the degree of coupling of spontaneous brain activity as measured with functional connectivity MR imaging (fcMR imaging) can accurately identify and localize epileptic discharges...