Jorge Sepulcre

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. ncbi Stepwise connectivity of the modal cortex reveals the multimodal organization of the human brain
    Jorge Sepulcre
    Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Neurosci 32:10649-61. 2012
  2. ncbi Network assemblies in the functional brain
    Jorge Sepulcre
    Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Curr Opin Neurol 25:384-91. 2012
  3. ncbi Modeling the effector - regulatory T cell cross-regulation reveals the intrinsic character of relapses in Multiple Sclerosis
    Nieves Velez de Mendizabal
    Division of Neurosciences, CIMA University of Navarra, Avenida Pio XII 55, 31008 Pamplona, Spain
    BMC Syst Biol 5:114. 2011
  4. ncbi The organization of local and distant functional connectivity in the human brain
    Jorge Sepulcre
    Howard Hughes Medical Institute, Cambridge, Massachusetts, United States of America
    PLoS Comput Biol 6:e1000808. 2010
  5. ncbi Individual variability in functional connectivity architecture of the human brain
    Sophia Mueller
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuron 77:586-95. 2013
  6. ncbi Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease
    Randy L Buckner
    Department of Psychology and Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138, USA
    J Neurosci 29:1860-73. 2009
  7. ncbi The dynamics of cortical and hippocampal atrophy in Alzheimer disease
    Mert R Sabuncu
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, 02129, USA
    Arch Neurol 68:1040-8. 2011
  8. ncbi The organization of the human cerebral cortex estimated by intrinsic functional connectivity
    B T Thomas Yeo
    Harvard University, Department of Psychology, Center for Brain Science, Cambridge, MA 02138, USA
    J Neurophysiol 106:1125-65. 2011
  9. ncbi Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden
    Alexander Drzezga
    Department of Radiology, Massachusetts General Hospital and Harvard University Medical School, Boston, MA 02114, USA
    Brain 134:1635-46. 2011
  10. ncbi Functional-anatomic fractionation of the brain's default network
    Jessica R Andrews-Hanna
    Department of Psychology and Center for Brain Science, Harvard University, Cambridge, MA 02138, USA
    Neuron 65:550-62. 2010

Collaborators

Detail Information

Publications12

  1. ncbi Stepwise connectivity of the modal cortex reveals the multimodal organization of the human brain
    Jorge Sepulcre
    Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Neurosci 32:10649-61. 2012
    ..We identify the large-scale multimodal integration network and essential connectivity axes for perceptual integration in the human brain...
  2. ncbi Network assemblies in the functional brain
    Jorge Sepulcre
    Division of Nuclear Medicine and Molecular Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Curr Opin Neurol 25:384-91. 2012
    ..This review focuses on recent advances in functional connectivity MRI and renewed interest in studying the large-scale functional network assemblies in the brain. We also consider some methodological aspects of graph theoretical analysis...
  3. ncbi Modeling the effector - regulatory T cell cross-regulation reveals the intrinsic character of relapses in Multiple Sclerosis
    Nieves Velez de Mendizabal
    Division of Neurosciences, CIMA University of Navarra, Avenida Pio XII 55, 31008 Pamplona, Spain
    BMC Syst Biol 5:114. 2011
    ..g. failure in central tolerance, activation by pathogens) that are able to trigger the immune system...
  4. ncbi The organization of local and distant functional connectivity in the human brain
    Jorge Sepulcre
    Howard Hughes Medical Institute, Cambridge, Massachusetts, United States of America
    PLoS Comput Biol 6:e1000808. 2010
    ..We discuss the implications of these observations and applications of the present method for exploring normal and atypical brain function...
  5. ncbi Individual variability in functional connectivity architecture of the human brain
    Sophia Mueller
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Neuron 77:586-95. 2013
    ..Our findings have potential implications for understanding brain evolution and development, guiding intervention, and interpreting statistical maps in neuroimaging...
  6. ncbi Cortical hubs revealed by intrinsic functional connectivity: mapping, assessment of stability, and relation to Alzheimer's disease
    Randy L Buckner
    Department of Psychology and Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138, USA
    J Neurosci 29:1860-73. 2009
    ....
  7. ncbi The dynamics of cortical and hippocampal atrophy in Alzheimer disease
    Mert R Sabuncu
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, 02129, USA
    Arch Neurol 68:1040-8. 2011
    ..To characterize rates of regional Alzheimer disease (AD)-specific brain atrophy across the presymptomatic, mild cognitive impairment, and dementia stages...
  8. ncbi The organization of the human cerebral cortex estimated by intrinsic functional connectivity
    B T Thomas Yeo
    Harvard University, Department of Psychology, Center for Brain Science, Cambridge, MA 02138, USA
    J Neurophysiol 106:1125-65. 2011
    ..We conclude by discussing the organization of these large-scale cerebral networks in relation to monkey anatomy and their potential evolutionary expansion in humans to support cognition...
  9. ncbi Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden
    Alexander Drzezga
    Department of Radiology, Massachusetts General Hospital and Harvard University Medical School, Boston, MA 02114, USA
    Brain 134:1635-46. 2011
    ....
  10. ncbi Functional-anatomic fractionation of the brain's default network
    Jessica R Andrews-Hanna
    Department of Psychology and Center for Brain Science, Harvard University, Cambridge, MA 02138, USA
    Neuron 65:550-62. 2010
    ..During certain experimentally directed and spontaneous acts of future-oriented thought, these dissociated components are simultaneously engaged, presumably to facilitate construction of mental models of personally significant events...
  11. ncbi Evidence from intrinsic activity that asymmetry of the human brain is controlled by multiple factors
    Hesheng Liu
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA 02129, USA
    Proc Natl Acad Sci U S A 106:20499-503. 2009
    ..These findings show the feasibility of measuring brain asymmetry using intrinsic activity fluctuations and suggest that multiple genetic or environmental mechanisms control cerebral lateralization...
  12. ncbi Localization of focal epileptic discharges using functional connectivity magnetic resonance imaging
    Steven M Stufflebeam
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    J Neurosurg 114:1693-7. 2011
    ..The object of this study was to investigate whether the degree of coupling of spontaneous brain activity as measured with functional connectivity MR imaging (fcMR imaging) can accurately identify and localize epileptic discharges...