Research Topics
Genomes and Genes | Daniel SchwartzSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Predicting protein post-translational modifications using meta-analysis of proteome scale data setsDaniel Schwartz
Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
Mol Cell Proteomics 8:365-79. 2009..New motif discovery is a byproduct of this approach, and the phosphorylation motif analyses provide strong evidence of evolutionary conservation of both known and novel kinase motifs...
Using the scan-x Web site to predict protein post-translational modificationsMichael F Chou
Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
Curr Protoc Bioinformatics . 2011..This tool is accessible from virtually any computer with a Web browser. The only requirement is a means of searching for a protein of interest in one of the represented organisms...
Extensive phosphorylation with overlapping specificity by Mycobacterium tuberculosis serine/threonine protein kinasesSladjana Prisic
Division of Infectious Diseases, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
Proc Natl Acad Sci U S A 107:7521-6. 2010..tuberculosis and create a resource for understanding how specific phosphorylation events modulate protein activity. The results further provide the potential to predict likely cognate STPKs for newly identified phosphoproteins...
Biological sequence motif discovery using motif-xMichael F Chou
Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
Curr Protoc Bioinformatics . 2011..The protocols presented demonstrate the use of motif-x in three common user scenarios...
Using bacteria to determine protein kinase specificity and predict target substratesMichael F Chou
Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
PLoS ONE 7:e52747. 2012....
Collection and motif-based prediction of phosphorylation sites in human virusesDaniel Schwartz
Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
Sci Signal 3:rs2. 2010....
An iterative statistical approach to the identification of protein phosphorylation motifs from large-scale data setsDaniel Schwartz
Department of Cell Biology, 240 Longwood Ave, Harvard Medical School, Boston, Massachusetts 02115, USA
Nat Biotechnol 23:1391-8. 2005....
Identification of 14-3-3epsilon substrates from embryonic murine brainBryan A Ballif
Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115, USA
J Proteome Res 5:2372-9. 2006..Phosphorylation of the deubiquitinating enzyme USP8 at serine 680 was found essential for its interaction with 14-3-3epsilon and for maintaining USP8 in the cytosol...
Ultraconserved elements: analyses of dosage sensitivity, motifs and boundariesCharleston W K Chiang
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA
Genetics 180:2277-93. 2008....
Phosphoproteomic analysis of the developing mouse brainBryan A Ballif
Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA
Mol Cell Proteomics 3:1093-101. 2004....
