Research Topics
Genomes and GenesSpecies | Markus SchürksSummaryAffiliation: Harvard University Country: USA Publications
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Publications
Migraine and mortality: a systematic review and meta-analysisMarkus Schürks
Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215 1204, USA
Cephalalgia 31:1301-14. 2011..To evaluate the evidence on the association between migraine and mortality...
Genetic determinants of cardiovascular events among women with migraine: a genome-wide association studyMarkus Schürks
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
PLoS ONE 6:e22106. 2011..Migraine is associated with an increased risk for cardiovascular disease (CVD). Both migraine and CVD are highly heritable. However, the genetic liability for CVD among migraineurs is unclear...
Tumour necrosis factor gene polymorphisms and migraine: a systematic review and meta-analysisMarkus Schürks
Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, 3rd f, Boston, MA 02215 1204, USA
Cephalalgia 31:1381-404. 2011..Data on the association between TNFα and TNFβ gene polymorphisms and migraine are conflicting...
Vascular risk factors, cardiovascular disease, and restless legs syndrome in menAnke C Winter
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Mass, USA
Am J Med 126:228-35, 235.e1-2. 2013..We therefore aim to evaluate the associations between prevalent vascular risk factors, prevalent cardiovascular disease, and restless legs syndrome...
Vascular risk factors, cardiovascular disease, and restless legs syndrome in womenAnke C Winter
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Mass, USA
Am J Med 126:220-7, 227.e1-2. 2013..We therefore aimed to analyze the relationships between vascular risk factors, prevalent cardiovascular disease, and restless legs syndrome...
Migraine and restless legs syndrome in womenMarkus Schürks
Brigham and Women s Hospital, Boston, MA, USA
Cephalalgia 32:382-9. 2012..Few clinic-based studies report an association between migraine and restless legs syndrome (RLS); however, population-based data are unavailable...
Association between polymorphisms in the beta2-adrenoceptor gene and migraine in womenMarkus Schürks
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
Headache 49:235-44. 2009..To investigate the role of three common polymorphisms in the beta2-adrenoceptor gene in migraine...
Migraine and risk of haemorrhagic stroke in women: prospective cohort studyTobias Kurth
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
BMJ 341:c3659. 2010..To examine the association between migraine and migraine aura status with risk of haemorrhagic stroke...
MTHFR 677C>T polymorphism and cluster headacheMarkus Schürks
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
Headache 51:201-7. 2011..An association between the 677C>T polymorphism (rs1801133) in the methylenetetrahydrofolate reductase gene (MTHFR) and cluster headache is plausible, but has not been investigated...
MTHFR 677C>T and ACE D/I polymorphisms in migraine: a systematic review and meta-analysisMarkus Schürks
Division of Preventive Medicine, Department of Medicine Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
Headache 50:588-99. 2010..Data on the association between the MTHFR 677C>T and ACE D/I polymorphisms and migraine including aura status are conflicting...
Migraine and cardiovascular disease: systematic review and meta-analysisMarkus Schürks
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215 1204, USA
BMJ 339:b3914. 2009..To evaluate the association between migraine and cardiovascular disease, including stroke, myocardial infarction, and death due to cardiovascular disease...
Association between polymorphisms in the beta2-adrenergic receptor gene with myocardial infarction and ischaemic stroke in womenMarkus Schürks
Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215 1204, USA
Thromb Haemost 101:351-8. 2009....
A candidate gene association study of 77 polymorphisms in migraineMarkus Schürks
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 CommonwealthAvenue East, 3rd Floor, Boston, MA 02215 1204, SUA
J Pain 10:759-66. 2009..Our data suggest an association of polymorphisms implicated in inflammatory pathways and migraine in women. TNF, CCR2, TGFB1, NOS3, and IL9 warrant further investigation...
Polymorphisms in the renin-angiotensin system and migraine in womenMarkus Schürks
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
Headache 49:292-9. 2009..Recent findings suggest an association between the renin-angiotensin system and migraine. However, genetic studies are scarce and controversial...
STin2 VNTR polymorphism in the serotonin transporter gene and migraine: pooled and meta-analysesMarkus Schürks
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, 3rd Floor, Boston, MA 02215 1204, USA
J Headache Pain 11:317-26. 2010..12 alleles compared to STin2.12 alleles, respectively, 10/12 and 10/10 genotypes compared to the 12/12 genotype against migraine among populations of European descent. Associations in non-European populations may differ...
Migraine and restless legs syndrome in menAnke C Winter
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, USA
Cephalalgia 33:130-5. 2013..Population-based data, however, have been limited to women. The aim of this study is to evaluate the association between migraine and RLS in a male cohort...
Migraine frequency and risk of cardiovascular disease in womenTobias Kurth
Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, USA
Neurology 73:581-8. 2009..Migraine has been associated with risk of cardiovascular disease (CVD). Data on the association between migraine frequency and CVD are sparse...
Migraine, migraine features, and cardiovascular diseaseMarkus Schürks
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
Headache 50:1031-40. 2010..Many studies support an association between migraine and cardiovascular disease (CVD). This association appears particularly in migraine with aura and is also modified by additional factors...
Migraine and functional outcome from ischemic cerebral events in womenPamela M Rist
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
Circulation 122:2551-7. 2010..Studies have linked migraine with aura to an increased risk of ischemic stroke, particularly among women. Data on the relationship of migraine and functional outcome from ischemic cerebral events are sparse...
Restless legs syndrome and risk of incident cardiovascular disease in women and men: prospective cohort studyAnke C Winter
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
BMJ Open 2:e000866. 2012..To evaluate the association between restless legs syndrome (RLS) and incident cardiovascular disease (CVD)...
Genome-wide association study reveals three susceptibility loci for common migraine in the general populationDaniel I Chasman
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Nat Genet 43:695-8. 2011..TRPM8 has been the focus of neuropathic pain models, whereas LRP1 modulates neuronal glutamate signaling, plausibly linking both genes to migraine pathophysiology...
Effects of vitamin E on stroke subtypes: meta-analysis of randomised controlled trialsMarkus Schürks
Division of Preventive Medicine, Department of Medicine Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
BMJ 341:c5702. 2010..To evaluate the effect of vitamin E supplementation on incident total, ischaemic, and haemorrhagic stroke...
Sex hormone receptor gene polymorphisms and migraine: a systematic review and meta-analysisMarkus Schürks
Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
Cephalalgia 30:1306-28. 2010..Data on the association between sex hormone receptor polymorphisms and migraine are conflicting...
5-HTTLPR polymorphism in the serotonin transporter gene and migraine: a systematic review and meta-analysisMarkus Schürks
Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
Cephalalgia 30:1296-305. 2010..For each study with genotype information, we calculated odds ratios (OR) and 95% confidence intervals (CI) assuming additive, dominant, and recessive genetic models. We then calculated pooled ORs and 95% CIs...
Dihydroergotamine: role in the treatment of migraineMarkus Schürks
Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
Expert Opin Drug Metab Toxicol 5:1141-8. 2009..Dihydroergotamine belongs to the oldest migraine-specific drugs. Mainly used by headache experts today, its properties are unfamiliar to many physicians...
Newest aspects on the association between migraine and cardiovascular disease: the role of modifying factorsTobias Kurth
INSERM Unit 708, Neuroepidemiology, Hopital de la Pitie Salpetriere, 47 Boulevard de l Hopital, 75651 Paris Cedex 13, France
Curr Pain Headache Rep 13:231-6. 2009..These new findings await confirmation in independent patient populations and are currently not sufficient to argue for a change in diagnostic testing or treatment...
Cluster headache and lifestyle habitsMarkus Schürks
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, 3rd Floor, Boston, MA 02215, USA
Curr Pain Headache Rep 12:115-21. 2008..Present studies are purely descriptive. Thus, the associations sketched give no information about the long-term effects of smoking or alcohol consumption on the course of CH...
Migraine, migraine aura, and cervical artery dissection: a systematic review and meta-analysisPamela M Rist
Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
Cephalalgia 31:886-96. 2011..We evaluated the current evidence on the association between migraine, including aura status, and cervical artery dissection...
Interrelationships among the MTHFR 677C>T polymorphism, migraine, and cardiovascular diseaseMarkus Schürks
Department of Medicine, Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02215 1204, USA
Neurology 71:505-13. 2008..Interrelationships among the MTHFR 677C>T polymorphism (rs1801133), migraine, and cardiovascular disease (CVD) are plausible but remain controversial...
Migraine, vascular risk, and cardiovascular events in women: prospective cohort studyTobias Kurth
Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
BMJ 337:a636. 2008..To evaluate whether the association between migraine with aura and increased risk of cardiovascular disease is modified by vascular risk groups as measured by the Framingham risk score for coronary heart disease...
Migraine features, associated symptoms and triggers: a principal component analysis in the Women's Health StudyMarkus Schürks
Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215 1204, USA
Cephalalgia 31:861-9. 2011..Migraine has a wide clinical spectrum. Our aim was to group information on migraine characteristics into meaningful components and to identify key components of the migraine phenotype...
Genetics of cluster headacheMarkus Schürks
Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
Curr Pain Headache Rep 14:132-9. 2010..Genetic studies in CH are notoriously difficult due to the complex nature of the disorder and the low prevalence of CH...
