Markus Schürks

Summary

Affiliation: Harvard University
Country: USA

Publications

  1. pmc Epigenetics in primary headaches: a new avenue for research
    Markus Schürks
    J Headache Pain 9:191-2. 2008
  2. doi Dihydroergotamine: role in the treatment of migraine
    Markus Schürks
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Expert Opin Drug Metab Toxicol 5:1141-8. 2009
  3. pmc MTHFR 677C->T and ACE D/I polymorphisms and migraine attack frequency in women
    M Schurks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215 1204, USA
    Cephalalgia 30:447-56. 2010
  4. pmc Agreement of self-reported migraine with ICHD-II criteria in the Women's Health Study
    M Schurks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, 3rd Fl, Boston, MA 02215 1204, USA
    Cephalalgia 29:1086-90. 2009
  5. pmc Migraine and cardiovascular disease: systematic review and meta-analysis
    Markus Schürks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215 1204, USA
    BMJ 339:b3914. 2009
  6. doi Genetics of cluster headache
    Markus Schürks
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Curr Pain Headache Rep 14:132-9. 2010
  7. pmc STin2 VNTR polymorphism in the serotonin transporter gene and migraine: pooled and meta-analyses
    Markus Schürks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, 3rd Floor, Boston, MA 02215 1204, USA
    J Headache Pain 11:317-26. 2010
  8. pmc 5-HTTLPR polymorphism in the serotonin transporter gene and migraine: a systematic review and meta-analysis
    Markus Schürks
    Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Cephalalgia 30:1296-305. 2010
  9. pmc Sex hormone receptor gene polymorphisms and migraine: a systematic review and meta-analysis
    Markus Schürks
    Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Cephalalgia 30:1306-28. 2010
  10. pmc Effects of vitamin E on stroke subtypes: meta-analysis of randomised controlled trials
    Markus Schürks
    Division of Preventive Medicine, Department of Medicine Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    BMJ 341:c5702. 2010

Detail Information

Publications43

  1. pmc Epigenetics in primary headaches: a new avenue for research
    Markus Schürks
    J Headache Pain 9:191-2. 2008
  2. doi Dihydroergotamine: role in the treatment of migraine
    Markus Schürks
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Expert Opin Drug Metab Toxicol 5:1141-8. 2009
    ..Dihydroergotamine belongs to the oldest migraine-specific drugs. Mainly used by headache experts today, its properties are unfamiliar to many physicians...
  3. pmc MTHFR 677C->T and ACE D/I polymorphisms and migraine attack frequency in women
    M Schurks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA 02215 1204, USA
    Cephalalgia 30:447-56. 2010
    ..78; 95% confidence interval 0.61, 0.99). We did not find a specific pattern of association of the ACE D/I polymorphism with attack frequency for MA or MoA...
  4. pmc Agreement of self-reported migraine with ICHD-II criteria in the Women's Health Study
    M Schurks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, 3rd Fl, Boston, MA 02215 1204, USA
    Cephalalgia 29:1086-90. 2009
    ..In addition, questionnaire-based migraine assessment according to full ICHD-II criteria in large population-based studies is feasible...
  5. pmc Migraine and cardiovascular disease: systematic review and meta-analysis
    Markus Schürks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215 1204, USA
    BMJ 339:b3914. 2009
    ..To evaluate the association between migraine and cardiovascular disease, including stroke, myocardial infarction, and death due to cardiovascular disease...
  6. doi Genetics of cluster headache
    Markus Schürks
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Curr Pain Headache Rep 14:132-9. 2010
    ..Genetic studies in CH are notoriously difficult due to the complex nature of the disorder and the low prevalence of CH...
  7. pmc STin2 VNTR polymorphism in the serotonin transporter gene and migraine: pooled and meta-analyses
    Markus Schürks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, 3rd Floor, Boston, MA 02215 1204, USA
    J Headache Pain 11:317-26. 2010
    ..12 alleles compared to STin2.12 alleles, respectively, 10/12 and 10/10 genotypes compared to the 12/12 genotype against migraine among populations of European descent. Associations in non-European populations may differ...
  8. pmc 5-HTTLPR polymorphism in the serotonin transporter gene and migraine: a systematic review and meta-analysis
    Markus Schürks
    Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Cephalalgia 30:1296-305. 2010
    ..For each study with genotype information, we calculated odds ratios (OR) and 95% confidence intervals (CI) assuming additive, dominant, and recessive genetic models. We then calculated pooled ORs and 95% CIs...
  9. pmc Sex hormone receptor gene polymorphisms and migraine: a systematic review and meta-analysis
    Markus Schürks
    Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Cephalalgia 30:1306-28. 2010
    ..Data on the association between sex hormone receptor polymorphisms and migraine are conflicting...
  10. pmc Effects of vitamin E on stroke subtypes: meta-analysis of randomised controlled trials
    Markus Schürks
    Division of Preventive Medicine, Department of Medicine Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    BMJ 341:c5702. 2010
    ..To evaluate the effect of vitamin E supplementation on incident total, ischaemic, and haemorrhagic stroke...
  11. pmc Migraine features, associated symptoms and triggers: a principal component analysis in the Women's Health Study
    Markus Schürks
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215 1204, USA
    Cephalalgia 31:861-9. 2011
    ..Migraine has a wide clinical spectrum. Our aim was to group information on migraine characteristics into meaningful components and to identify key components of the migraine phenotype...
  12. pmc A candidate gene association study of 77 polymorphisms in migraine
    Markus Schürks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 CommonwealthAvenue East, 3rd Floor, Boston, MA 02215 1204, SUA
    J Pain 10:759-66. 2009
    ..Our data suggest an association of polymorphisms implicated in inflammatory pathways and migraine in women. TNF, CCR2, TGFB1, NOS3, and IL9 warrant further investigation...
  13. pmc ACE D/I polymorphism, migraine, and cardiovascular disease in women
    M Schurks
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, 3rd Fl, Boston, MA 02215 1204, USA
    Neurology 72:650-6. 2009
    ..Interrelationships among the ACE deletion/insertion (D/I) polymorphism (rs1799752), migraine, and cardiovascular disease (CVD) are biologically plausible but remain controversial...
  14. pmc Association between polymorphisms in the beta2-adrenergic receptor gene with myocardial infarction and ischaemic stroke in women
    Markus Schürks
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215 1204, USA
    Thromb Haemost 101:351-8. 2009
    ....
  15. doi [Pathophysiology of migraine and clinical implications]
    M Schurks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, 3rd Fl, Boston, MA 02215 1204, USA
    Schmerz 22:523-6, 528-30. 2008
    ..Triptans have a peripheral and central mode of action, but they are no longer effective once central sensitization has occurred...
  16. ncbi Cluster headache and lifestyle habits
    Markus Schürks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, 3rd Floor, Boston, MA 02215, USA
    Curr Pain Headache Rep 12:115-21. 2008
    ..Present studies are purely descriptive. Thus, the associations sketched give no information about the long-term effects of smoking or alcohol consumption on the course of CH...
  17. doi [What is migraine?]
    M Schurks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, 02215 1204, Boston, USA
    Nervenarzt 80:1154, 1156-9. 2009
    ..The age- and sex-specific pattern along with the effect of external factors on the course of migraine argue in favor of the involvement of epigenetic mechanisms. Knowledge about migraine is still limited, which hampers a definition...
  18. ncbi Migraine, allodynia, and implications for treatment
    M Schurks
    Division of Preventive Medicine, Department of Medicine, Brigham and Womens Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Eur J Neurol 15:1279-85. 2008
    ..Regardless--based on available randomized controlled trials--the recommendation prevails to initiate abortive treatment as soon as possible after attack onset when pain is still mild...
  19. pmc Vascular risk factors, cardiovascular disease, and restless legs syndrome in men
    Anke C Winter
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Mass, USA
    Am J Med 126:228-35, 235.e1-2. 2013
    ..We therefore aim to evaluate the associations between prevalent vascular risk factors, prevalent cardiovascular disease, and restless legs syndrome...
  20. pmc Vascular risk factors, cardiovascular disease, and restless legs syndrome in women
    Anke C Winter
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, Mass, USA
    Am J Med 126:220-7, 227.e1-2. 2013
    ..We therefore aimed to analyze the relationships between vascular risk factors, prevalent cardiovascular disease, and restless legs syndrome...
  21. pmc Tumour necrosis factor gene polymorphisms and migraine: a systematic review and meta-analysis
    Markus Schürks
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, 3rd f, Boston, MA 02215 1204, USA
    Cephalalgia 31:1381-404. 2011
    ..Data on the association between TNFα and TNFβ gene polymorphisms and migraine are conflicting...
  22. pmc MTHFR 677C>T and ACE D/I polymorphisms in migraine: a systematic review and meta-analysis
    Markus Schürks
    Division of Preventive Medicine, Department of Medicine Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Headache 50:588-99. 2010
    ..Data on the association between the MTHFR 677C>T and ACE D/I polymorphisms and migraine including aura status are conflicting...
  23. pmc Migraine and restless legs syndrome in men
    Anke C Winter
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, USA
    Cephalalgia 33:130-5. 2013
    ..Population-based data, however, have been limited to women. The aim of this study is to evaluate the association between migraine and RLS in a male cohort...
  24. pmc Migraine and restless legs syndrome in women
    Markus Schürks
    Brigham and Women s Hospital, Boston, MA, USA
    Cephalalgia 32:382-9. 2012
    ..Few clinic-based studies report an association between migraine and restless legs syndrome (RLS); however, population-based data are unavailable...
  25. pmc Association between polymorphisms in the beta2-adrenoceptor gene and migraine in women
    Markus Schürks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Headache 49:235-44. 2009
    ..To investigate the role of three common polymorphisms in the beta2-adrenoceptor gene in migraine...
  26. doi MTHFR 677C>T polymorphism and cluster headache
    Markus Schürks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Headache 51:201-7. 2011
    ..An association between the 677C>T polymorphism (rs1801133) in the methylenetetrahydrofolate reductase gene (MTHFR) and cluster headache is plausible, but has not been investigated...
  27. pmc Migraine and risk of haemorrhagic stroke in women: prospective cohort study
    Tobias Kurth
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    BMJ 341:c3659. 2010
    ..To examine the association between migraine and migraine aura status with risk of haemorrhagic stroke...
  28. pmc Genetic determinants of cardiovascular events among women with migraine: a genome-wide association study
    Markus Schürks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS ONE 6:e22106. 2011
    ..Migraine is associated with an increased risk for cardiovascular disease (CVD). Both migraine and CVD are highly heritable. However, the genetic liability for CVD among migraineurs is unclear...
  29. doi Circulating fetuin-A and risk of ischemic stroke in women
    Monik C Jimenez
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA
    Clin Chem 60:165-73. 2014
    ..In a recent study, higher circulating fetuin-A was associated with cardiovascular events, particularly ischemic stroke. However, these data have not been replicated...
  30. pmc Interrelationships among the MTHFR 677C>T polymorphism, migraine, and cardiovascular disease
    Markus Schürks
    Department of Medicine, Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA 02215 1204, USA
    Neurology 71:505-13. 2008
    ..Interrelationships among the MTHFR 677C>T polymorphism (rs1801133), migraine, and cardiovascular disease (CVD) are plausible but remain controversial...
  31. pmc Migraine, migraine features, and cardiovascular disease
    Markus Schürks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Headache 50:1031-40. 2010
    ..Many studies support an association between migraine and cardiovascular disease (CVD). This association appears particularly in migraine with aura and is also modified by additional factors...
  32. pmc Polymorphisms in the renin-angiotensin system and migraine in women
    Markus Schürks
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02215 1204, USA
    Headache 49:292-9. 2009
    ..Recent findings suggest an association between the renin-angiotensin system and migraine. However, genetic studies are scarce and controversial...
  33. pmc Migraine, headache, and the risk of depression: Prospective cohort study
    Pamela M Rist
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, MA 02215, USA
    Cephalalgia 33:1017-25. 2013
    ..While cross-sectional studies have shown associations between migraine and depression, few studies have been able to evaluate the association between migraine and incident depression...
  34. pmc Migraine frequency and risk of cardiovascular disease in women
    Tobias Kurth
    Division of Preventive Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, USA
    Neurology 73:581-8. 2009
    ..Migraine has been associated with risk of cardiovascular disease (CVD). Data on the association between migraine frequency and CVD are sparse...
  35. pmc Migraine and functional outcome from ischemic cerebral events in women
    Pamela M Rist
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass, USA
    Circulation 122:2551-7. 2010
    ..Studies have linked migraine with aura to an increased risk of ischemic stroke, particularly among women. Data on the relationship of migraine and functional outcome from ischemic cerebral events are sparse...
  36. pmc Restless legs syndrome and risk of incident cardiovascular disease in women and men: prospective cohort study
    Anke C Winter
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    BMJ Open 2:e000866. 2012
    ..To evaluate the association between restless legs syndrome (RLS) and incident cardiovascular disease (CVD)...
  37. ncbi Newest aspects on the association between migraine and cardiovascular disease: the role of modifying factors
    Tobias Kurth
    INSERM Unit 708, Neuroepidemiology, Hopital de la Pitie Salpetriere, 47 Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Curr Pain Headache Rep 13:231-6. 2009
    ..These new findings await confirmation in independent patient populations and are currently not sufficient to argue for a change in diagnostic testing or treatment...
  38. pmc Low dehydroepiandrosterone sulfate is associated with increased risk of ischemic stroke among women
    Monik C Jimenez
    Division of Preventive Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Stroke 44:1784-9. 2013
    ..DHEAS may influence ischemic stroke risk through atherosclerotic-related mechanisms (endothelial function and smooth muscle cell proliferation) or insulin resistance...
  39. pmc Migraine and mortality: a systematic review and meta-analysis
    Markus Schürks
    Division of Preventive Medicine, Brigham and Women s Hospital, 900 Commonwealth Avenue East, Boston, MA 02215 1204, USA
    Cephalalgia 31:1301-14. 2011
    ..To evaluate the evidence on the association between migraine and mortality...
  40. pmc Genome-wide association study reveals three susceptibility loci for common migraine in the general population
    Daniel I Chasman
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Nat Genet 43:695-8. 2011
    ..TRPM8 has been the focus of neuropathic pain models, whereas LRP1 modulates neuronal glutamate signaling, plausibly linking both genes to migraine pathophysiology...
  41. pmc Migraine, migraine aura, and cervical artery dissection: a systematic review and meta-analysis
    Pamela M Rist
    Brigham and Women s Hospital, Harvard Medical School, 900 Commonwealth Avenue East, Boston, MA 02215, USA
    Cephalalgia 31:886-96. 2011
    ..We evaluated the current evidence on the association between migraine, including aura status, and cervical artery dissection...
  42. pmc Migraine, vascular risk, and cardiovascular events in women: prospective cohort study
    Tobias Kurth
    Division of Preventive Medicine, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    BMJ 337:a636. 2008
    ..To evaluate whether the association between migraine with aura and increased risk of cardiovascular disease is modified by vascular risk groups as measured by the Framingham risk score for coronary heart disease...
  43. doi Genome-wide meta-analysis identifies new susceptibility loci for migraine
    Verneri Anttila
    Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge, UK
    Nat Genet 45:912-7. 2013
    ..Three of these loci were identified in disease subgroup analyses. Brain tissue expression quantitative trait locus analysis suggests potential functional candidate genes at four loci: APOA1BP, TBC1D7, FUT9, STAT6 and ATP5B...